DE60001177D1 - LC-NMR System, enthaltend eine Vorrichtung zum Einfangen von mindestens einer Komponente eines Chromatographieflusses - Google Patents

LC-NMR System, enthaltend eine Vorrichtung zum Einfangen von mindestens einer Komponente eines Chromatographieflusses

Info

Publication number
DE60001177D1
DE60001177D1 DE60001177T DE60001177T DE60001177D1 DE 60001177 D1 DE60001177 D1 DE 60001177D1 DE 60001177 T DE60001177 T DE 60001177T DE 60001177 T DE60001177 T DE 60001177T DE 60001177 D1 DE60001177 D1 DE 60001177D1
Authority
DE
Germany
Prior art keywords
capturing
component
system containing
nmr system
chromatography flow
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60001177T
Other languages
English (en)
Other versions
DE60001177T2 (de
Inventor
Martin Hofmann
Manfred Dr Spraul
Markus Dr Godejohann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bruker Biospin GmbH
Original Assignee
Bruker Biospin GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bruker Biospin GmbH filed Critical Bruker Biospin GmbH
Publication of DE60001177D1 publication Critical patent/DE60001177D1/de
Application granted granted Critical
Publication of DE60001177T2 publication Critical patent/DE60001177T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/84—Preparation of the fraction to be distributed
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/84—Preparation of the fraction to be distributed
    • G01N2030/8411—Intermediate storage of effluent, including condensation on surface
    • G01N2030/8417—Intermediate storage of effluent, including condensation on surface the store moving as a whole, e.g. moving wire
DE60001177T 2000-10-25 2000-10-25 LC-NMR System, enthaltend eine Vorrichtung zum Einfangen von mindestens einer Komponente eines Chromatographieflusses Expired - Lifetime DE60001177T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP00123101A EP1202054B1 (de) 2000-10-25 2000-10-25 LC-NMR System, enthaltend eine Vorrichtung zum Einfangen von mindestens einer Komponente eines Chromatographieflusses

Publications (2)

Publication Number Publication Date
DE60001177D1 true DE60001177D1 (de) 2003-02-13
DE60001177T2 DE60001177T2 (de) 2003-10-23

Family

ID=8170187

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60001177T Expired - Lifetime DE60001177T2 (de) 2000-10-25 2000-10-25 LC-NMR System, enthaltend eine Vorrichtung zum Einfangen von mindestens einer Komponente eines Chromatographieflusses

Country Status (3)

Country Link
US (1) US6614228B2 (de)
EP (1) EP1202054B1 (de)
DE (1) DE60001177T2 (de)

Families Citing this family (47)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2290731A1 (en) * 1999-11-26 2001-05-26 D. Jed Harrison Apparatus and method for trapping bead based reagents within microfluidic analysis system
US6432290B1 (en) 1999-11-26 2002-08-13 The Governors Of The University Of Alberta Apparatus and method for trapping bead based reagents within microfluidic analysis systems
DE60001177T2 (de) * 2000-10-25 2003-10-23 Bruker Biospin Gmbh LC-NMR System, enthaltend eine Vorrichtung zum Einfangen von mindestens einer Komponente eines Chromatographieflusses
US6774634B2 (en) * 2002-01-29 2004-08-10 Varian, Inc. Automated NMR analysis using solvents and sample tube materials to control frequency shifts
US20030217923A1 (en) * 2002-05-24 2003-11-27 Harrison D. Jed Apparatus and method for trapping bead based reagents within microfluidic analysis systems
DE60200516T2 (de) 2002-08-30 2004-09-23 Bruker Biospin Gmbh Mehrwegschaltventil für ein Flüssigkeitsströmungssystem
EP2404676A1 (de) 2002-12-30 2012-01-11 The Regents of the University of California Mikrofluidische Steuerungsstrukturen
JP3816883B2 (ja) * 2003-03-06 2006-08-30 株式会社日立ハイテクノロジーズ 液体クロマトグラフ質量分析装置
CA2536809A1 (en) * 2003-09-05 2005-03-17 Sumitomo Chemical Company, Limited Liquid chromatographic apparatus
FR2867089B1 (fr) * 2004-03-03 2006-06-09 Bionisis Sa Installation de separation de composants dans plusieurs voies paralleles
ITMI20040740A1 (it) * 2004-04-15 2004-07-15 Ecoenergetics S R L Analizzatore automatico per la rilevazione di azoto proveniente da composti organici
DE102004024070B3 (de) 2004-05-13 2005-11-03 Bruker Biospin Gmbh Trocknung von SPE-Kartuschen
US7799553B2 (en) * 2004-06-01 2010-09-21 The Regents Of The University Of California Microfabricated integrated DNA analysis system
CN102759466A (zh) 2004-09-15 2012-10-31 英特基因有限公司 微流体装置
US7749365B2 (en) 2006-02-01 2010-07-06 IntegenX, Inc. Optimized sample injection structures in microfluidic separations
WO2008030631A2 (en) 2006-02-03 2008-03-13 Microchip Biotechnologies, Inc. Microfluidic devices
KR100623090B1 (ko) * 2006-03-07 2006-09-13 가톨릭대학교 산학협력단 자기공명영상 장비를 이용한 자기공명분광 성능 평가용팬텀
US7766033B2 (en) * 2006-03-22 2010-08-03 The Regents Of The University Of California Multiplexed latching valves for microfluidic devices and processors
DE102006022953B3 (de) * 2006-05-17 2007-12-20 Bruker Biospin Gmbh Verfahren zur Kopplung eines Gaschromatographen mit einem NMR-Spektrometer und zugehörige Apparatur
WO2008052138A2 (en) 2006-10-25 2008-05-02 The Regents Of The University Of California Inline-injection microdevice and microfabricated integrated dna analysis system using same
CN101715483A (zh) 2007-02-05 2010-05-26 微芯片生物工艺学股份有限公司 微流体和纳米流体装置、系统和应用
WO2009015296A1 (en) 2007-07-24 2009-01-29 The Regents Of The University Of California Microfabricated dropley generator
JP5433580B2 (ja) 2007-11-02 2014-03-05 バイオシアス ライフ サイエンシーズ， インコーポレイテッド 試料注入システム
KR20110030415A (ko) 2008-01-22 2011-03-23 인터젠엑스 인크. 만능 샘플 제조 시스템 및 집적 분석 시스템에서의 용도
US8672532B2 (en) 2008-12-31 2014-03-18 Integenx Inc. Microfluidic methods
WO2010118414A1 (en) * 2009-04-10 2010-10-14 Waters Technologies Corporation Apparatus and method for coupled lc-nmr analysis
US9470664B2 (en) 2009-04-10 2016-10-18 Waters Technologies Corporation Chromatographic interface
KR20120030130A (ko) 2009-06-02 2012-03-27 인터젠엑스 인크. 다이아프램 밸브를 포함하는 유체 장치
EP3586945A3 (de) 2009-06-05 2020-03-04 IntegenX Inc. Universelles probenvorbereitungssystem und verwendung in einem integrierten analysesystem
US8584703B2 (en) 2009-12-01 2013-11-19 Integenx Inc. Device with diaphragm valve
US8512538B2 (en) 2010-05-28 2013-08-20 Integenx Inc. Capillary electrophoresis device
WO2012024657A1 (en) 2010-08-20 2012-02-23 IntegenX, Inc. Microfluidic devices with mechanically-sealed diaphragm valves
US9121058B2 (en) 2010-08-20 2015-09-01 Integenx Inc. Linear valve arrays
US20150136604A1 (en) 2011-10-21 2015-05-21 Integenx Inc. Sample preparation, processing and analysis systems
US10865440B2 (en) 2011-10-21 2020-12-15 IntegenX, Inc. Sample preparation, processing and analysis systems
CN114471756B (zh) 2013-11-18 2024-04-16 尹特根埃克斯有限公司 用于样本分析的卡盒和仪器
US10208332B2 (en) 2014-05-21 2019-02-19 Integenx Inc. Fluidic cartridge with valve mechanism
WO2016065073A1 (en) 2014-10-22 2016-04-28 Integenx Inc. Systems and methods for sample preparation, processing and analysis
EP3178557B1 (de) 2015-12-11 2018-11-28 Biotage AB Vorrichtung zur flusssteuerung
US11067548B2 (en) 2016-04-04 2021-07-20 Entech Instruments Inc. Multi-capillary column pre-concentration system for enhanced sensitivity in gas chromatography (GC) and gas chromatography-mass spectrometry (GCMS)
CN110383059A (zh) * 2017-03-16 2019-10-25 株式会社岛津制作所 分液色谱仪
US10935524B2 (en) 2017-07-27 2021-03-02 CEM Corporation, Lucidity Division Gas chromatograph device with inductively heated column and method of use thereof
EP3688453A1 (de) 2017-10-25 2020-08-05 Entech Instruments Inc. Probenvorkonzentrationssystem und verfahren zur verwendung mit gaschromatografie
US11162925B2 (en) 2017-11-03 2021-11-02 Entech Instruments Inc. High performance sub-ambient temperature multi-capillary column preconcentration system for volatile chemical analysis by gas chromatography
DE102019205509B3 (de) 2019-04-16 2020-10-08 Bruker Biospin Gmbh Totvolumen-freie Fraktionssammel-Vorrichtung
US11946912B2 (en) 2020-06-30 2024-04-02 Entech Instruments Inc. System and method of trace-level analysis of chemical compounds
WO2022131075A1 (ja) * 2020-12-16 2022-06-23 株式会社日立ハイテク 液体クロマトグラフのカラム接続方法及び液体クロマトグラフ

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3902848A (en) * 1974-06-26 1975-09-02 Research Corp Liquid chromatography detector and method
JP2892795B2 (ja) * 1989-09-12 1999-05-17 エーザイ株式会社 高速液体クロマトグラフィー質量分析における移動相の変換方法と装置
DE4104075C1 (de) * 1991-02-11 1992-03-19 Bruker Analytische Messtechnik Gmbh, 7512 Rheinstetten, De
US5449902A (en) * 1992-12-17 1995-09-12 Hitachi, Ltd. Apparatus for directly coupling analytical column with mass spectrometer
US5898493A (en) * 1996-06-07 1999-04-27 Iowa State University Research Foundation, Inc. Capillary electrophoresis-fluorescence line narrowing system (CE-FLNS) for on-line structural characterization
US6497820B1 (en) * 1998-02-03 2002-12-24 Arqule, Inc. Rapid method for separation of small molecules using reverse phase high performance liquid chromatography
US6498040B1 (en) * 1998-05-26 2002-12-24 Eisai Co., Ltd. HPLC apparatus for fractioning and preparing sample for NMR spectrometry and method of changing mobile phase
DE60001177T2 (de) * 2000-10-25 2003-10-23 Bruker Biospin Gmbh LC-NMR System, enthaltend eine Vorrichtung zum Einfangen von mindestens einer Komponente eines Chromatographieflusses

Also Published As

Publication number Publication date
US6614228B2 (en) 2003-09-02
EP1202054A1 (de) 2002-05-02
EP1202054B1 (de) 2003-01-08
US20020088946A1 (en) 2002-07-11
DE60001177T2 (de) 2003-10-23

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