DE593911C - Solid carriers for therapeutic and technical purposes - Google Patents

Solid carriers for therapeutic and technical purposes

Info

Publication number
DE593911C
DE593911C DEG79338D DEG0079338D DE593911C DE 593911 C DE593911 C DE 593911C DE G79338 D DEG79338 D DE G79338D DE G0079338 D DEG0079338 D DE G0079338D DE 593911 C DE593911 C DE 593911C
Authority
DE
Germany
Prior art keywords
therapeutic
solid carriers
technical purposes
gelatin
substances
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DEG79338D
Other languages
German (de)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ASTA AG CHEM FAB
Original Assignee
ASTA AG CHEM FAB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ASTA AG CHEM FAB filed Critical ASTA AG CHEM FAB
Priority to DEG79338D priority Critical patent/DE593911C/en
Application granted granted Critical
Publication of DE593911C publication Critical patent/DE593911C/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicinal Preparation (AREA)

Description

Feste Trägerstoffe für therapeutische und technische Zwecke Quellbare Stoffe, insbesondere Gelatine und gehärtete Gelatine, sind bereits als Trägerstoffe bekannt. Auch hat man Citronensäure enthaltenden Gelatinelösungen Arzneimittel zugesetzt. Der Gelatine haftet jedoch bei ihrer Verwendung als Trägerstoff, auch bei Gegenwart von Citronensäure, der Nachteil an, daß sie nicht immer gegenüber den ihr zugesetzten Stoffen, wie Jodsalzen, Nitriten usw., indifferent ist.Solid carriers for therapeutic and technical purposes, swellable Substances, especially gelatin and hardened gelatin, are already used as carriers known. Medicinal products have also been added to gelatin solutions containing citric acid. However, the gelatine adheres when it is used as a carrier, even when it is present of citric acid, the disadvantage that it is not always compared to the added Substances such as iodized salts, nitrites, etc., is indifferent.

Es wurde gefunden, daß mit Salzsäure versetzte Gelatine, sei es in Gegenwart von Flüssigkeiten - also als feste kolloidale Lösungen -, sei es auch nach Entfernung der Flüssigkeit - also in trockenem Zustande, als Gel - sich als Trägerstoffe sowohl für therapeutische als auch für tecluiische Zwecke, z. B. zur Herstellung von Schädlingsbekämpfungsmitteln, eignet. So können beispielsweise wasserlösliche Stoffe in der mit Salzsäure versetzten Gelatine ohne weiteres gelöst oder diesem Gelatine-Salzsäure-Gemisch gelöst zugesetzt werden. Wasserunlösliche Stoffe können diesem Gelatine-Salzsäure-Gemisch in geeigneter. Weise beigemischt werden. Dies gilt nicht nur für feste, in Wasser unlösliche Stoffe, sondern auch für in Wasser unlösliche Flüssigkeiten, wie Kreosot, Guajacol u. dgl. Gegebenenfalls können die wasserunlöslichen Stoffe auch in anderen geeigneten Lösungsmitteln gelöst zugesetzt werden. Man kann derartige Massen trocken oder auch feucht in geeigneter Weise zerkleinern oder durch Tablettieren, " Ausgießen u. dgl. in geeigneter Weise formen, wobei diesen Trägerstoffen vordem Trocknen oder auch nach dem Trocknen andere Stoffe zugemischt sein können.It has been found that gelatin mixed with hydrochloric acid, be it in Presence of liquids - i.e. as solid colloidal solutions - be it either after removal of the liquid - that is, in the dry state, as a gel - it turns out to be Carriers for both therapeutic and tecluiische purposes, e.g. B. to Manufacture of pesticides, suitable. For example, water-soluble Substances in the gelatin mixed with hydrochloric acid are easily dissolved or this Gelatin-hydrochloric acid mixture can be added in solution. Substances that are insoluble in water can this gelatin-hydrochloric acid mixture is suitable. Way to be mixed. this applies not only to solid substances that are insoluble in water, but also to water insoluble liquids such as creosote, guaiacol and the like added to water-insoluble substances dissolved in other suitable solvents will. Such masses can be comminuted in a suitable manner, dry or wet or by tabletting, "pouring out" and the like in a suitable manner, whereby these Carriers mixed with other substances before drying or after drying could be.

Die erhaltenen Präparate sind haltbar. Es .ist außerdem auch möglich, die Trägerstoffe in üblicher Weise, z. B. durch Formaldehyd, zu härten bzw. gehärtet zu verwenden. Die Menge der zu verwendenden Salzsäure wechselt nach der Art der jeweils zu verwendenden Gelatine und ist daher von Fall zu Fall durch Versuche festzustellen.The preparations obtained are stable. It is also possible the carriers in the usual way, for. B. by formaldehyde to harden or hardened to use. The amount of hydrochloric acid to be used varies according to the type of gelatine to be used in each case and must therefore be determined by tests on a case-by-case basis.

Als Lösungsmittel wird man, von Ausnahmefällen abgesehen, im allgemeinen Wasser. verwenden.The solvent used is, apart from exceptional cases, in general Water. use.

Claims (1)

PA TRNT ANSPRUCI3 Feste Trägerstoffe für therapeutische und technische Zwecke, bestehend aus einem Gemisch von Gelatine oder festen Gelatinelösungen mit Salzsäure.PA TRNT ANSPRUCI3 Solid carriers for therapeutic and technical Purposes consisting of a mixture of gelatin or solid gelatin solutions with Hydrochloric acid.
DEG79338D 1931-04-03 1931-04-03 Solid carriers for therapeutic and technical purposes Expired DE593911C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DEG79338D DE593911C (en) 1931-04-03 1931-04-03 Solid carriers for therapeutic and technical purposes

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DEG79338D DE593911C (en) 1931-04-03 1931-04-03 Solid carriers for therapeutic and technical purposes

Publications (1)

Publication Number Publication Date
DE593911C true DE593911C (en) 1934-04-25

Family

ID=7136861

Family Applications (1)

Application Number Title Priority Date Filing Date
DEG79338D Expired DE593911C (en) 1931-04-03 1931-04-03 Solid carriers for therapeutic and technical purposes

Country Status (1)

Country Link
DE (1) DE593911C (en)

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