DE50213751D1 - Matrix-filmtablette mit kontrollierter freisetzung von natürlichen gemischen konjugierter oestrogene - Google Patents

Matrix-filmtablette mit kontrollierter freisetzung von natürlichen gemischen konjugierter oestrogene

Info

Publication number
DE50213751D1
DE50213751D1 DE50213751T DE50213751T DE50213751D1 DE 50213751 D1 DE50213751 D1 DE 50213751D1 DE 50213751 T DE50213751 T DE 50213751T DE 50213751 T DE50213751 T DE 50213751T DE 50213751 D1 DE50213751 D1 DE 50213751D1
Authority
DE
Germany
Prior art keywords
oestrogene
conjugated
controlled release
matrix film
natural mixtures
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE50213751T
Other languages
German (de)
English (en)
Inventor
Bernd Thumbeck
Klaus Budde
Gerhard Kristen
Margit Wiards
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Products GmbH
Original Assignee
Solvay Pharmaceuticals GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Solvay Pharmaceuticals GmbH filed Critical Solvay Pharmaceuticals GmbH
Application granted granted Critical
Publication of DE50213751D1 publication Critical patent/DE50213751D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/30—Oestrogens

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Endocrinology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Diabetes (AREA)
  • Reproductive Health (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
DE50213751T 2001-12-14 2002-12-12 Matrix-filmtablette mit kontrollierter freisetzung von natürlichen gemischen konjugierter oestrogene Expired - Lifetime DE50213751D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP01129830 2001-12-14
PCT/EP2002/014103 WO2003051336A1 (de) 2001-12-14 2002-12-12 Matrix-filmtablette mit kontrollierter freisetzung von natürlichen gemischen konjugierter oestrogene

Publications (1)

Publication Number Publication Date
DE50213751D1 true DE50213751D1 (de) 2009-09-17

Family

ID=8179548

Family Applications (1)

Application Number Title Priority Date Filing Date
DE50213751T Expired - Lifetime DE50213751D1 (de) 2001-12-14 2002-12-12 Matrix-filmtablette mit kontrollierter freisetzung von natürlichen gemischen konjugierter oestrogene

Country Status (18)

Country Link
US (1) US8268351B2 (enExample)
EP (1) EP1465602B1 (enExample)
JP (1) JP4695837B2 (enExample)
CN (1) CN100542538C (enExample)
AR (1) AR037760A1 (enExample)
AT (1) ATE438384T1 (enExample)
AU (1) AU2002361396B2 (enExample)
BR (1) BR0215044A (enExample)
CA (1) CA2470207C (enExample)
DE (1) DE50213751D1 (enExample)
DK (1) DK1465602T3 (enExample)
ES (1) ES2328910T3 (enExample)
MX (1) MXPA04005769A (enExample)
PL (1) PL205739B1 (enExample)
PT (1) PT1465602E (enExample)
SI (1) SI1465602T1 (enExample)
TW (1) TWI252111B (enExample)
WO (1) WO2003051336A1 (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7303763B2 (en) * 2001-02-12 2007-12-04 Watson Laboratories, Inc. Compositions for conjugated estrogens and associated methods
ES2377729T3 (es) * 2002-02-21 2012-03-30 Valeant International (Barbados) Srl Formulaciones de liberación modificada de al menos una forma de tramadol
US8323692B2 (en) 2002-02-21 2012-12-04 Valeant International Bermuda Controlled release dosage forms
US6992075B2 (en) * 2003-04-04 2006-01-31 Barr Laboratories, Inc. C(14) estrogenic compounds
GB0329498D0 (en) * 2003-12-19 2004-01-28 Novartis Ag Organic compounds
JP4521554B2 (ja) * 2004-03-31 2010-08-11 マイラン製薬株式会社 シクロスポリン製剤
DE102004035938A1 (de) * 2004-07-23 2006-02-16 Röhm GmbH & Co. KG Verfahren zur Herstellung von überzogenen Arzneiformen mit stabilem Wirkstofffreigabeprofil
EP1679065A1 (en) 2005-01-07 2006-07-12 OctoPlus Sciences B.V. Controlled release compositions for interferon based on PEGT/PBT block copolymers
JP5162141B2 (ja) * 2007-02-20 2013-03-13 エスエス製薬株式会社 フィルムコーティング用組成物
JP4864024B2 (ja) * 2008-02-15 2012-01-25 エスエス製薬株式会社 時限放出製剤
US20090232897A1 (en) * 2008-03-14 2009-09-17 Bijayananda Sahoo Pharmaceutical compositions comprising conjugated estrogens

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3753767A (en) * 1971-08-02 1973-08-21 Colgate Palmolive Co Method of sugar-coating tablets
DE3535536A1 (de) * 1985-10-04 1987-04-09 Lentia Gmbh Verfahren zum gleichzeitigen trocknen und granulieren von extraktstoffen aus enteiweisstem kaelberblut
US5208225A (en) * 1986-02-27 1993-05-04 Warner-Lambert Company Compositions containing fixed combinations
US5108995A (en) * 1987-09-24 1992-04-28 Jencap Research Ltd. Hormone preparation and method
EP0322020A1 (en) * 1987-12-22 1989-06-28 Akzo N.V. Pharmaceutical dosage unit for treating climacteric complaints and osteoporosis
HU9500322D0 (en) * 1994-02-08 1995-03-28 Solvay Deutschland Process for separating estrogenes from the urine of mares with foal
US5458887A (en) * 1994-03-02 1995-10-17 Andrx Pharmaceuticals, Inc. Controlled release tablet formulation
DE4429398C2 (de) * 1994-08-09 1997-09-11 Jenapharm Gmbh Verwendung von Estra-1,3,5(10)-trien-Derivaten zur hormonalen Kontrazeption
IE80467B1 (en) * 1995-07-03 1998-07-29 Elan Corp Plc Controlled release formulations for poorly soluble drugs
WO1997004752A1 (en) * 1995-07-26 1997-02-13 Duramed Pharmaceuticals, Inc. Pharmaceutical compositions of conjugated estrogens and methods for their use
DE19540253C2 (de) * 1995-10-28 1998-06-04 Jenapharm Gmbh Mehrphasenpräparat zur Kontrazeption auf der Basis natürlicher Estrogene
CN1101683C (zh) * 1996-08-30 2003-02-19 索尔瓦药物有限公司 由牝马尿获取雌激素的方法
CN1101682C (zh) * 1996-08-30 2003-02-19 索尔瓦药物有限公司 由牝马尿液获取雌激素的方法
DK0923381T3 (da) 1996-08-30 2004-05-10 Solvay Pharm Gmbh Fremgangsmåde til fremstilling af östrogener ud fra hoppeurin
ATE264110T1 (de) 1996-08-30 2004-04-15 Solvay Pharm Gmbh Prozess zur gewinnung von oestrogenen aus stutenharn
AU8699298A (en) * 1997-08-11 1999-03-01 Alza Corporation Prolonged release active agent dosage form adapted for gastric retention
US6022554A (en) * 1997-12-15 2000-02-08 American Home Products Corporation Polymeric microporous film coated subcutaneous implant
DE19845358A1 (de) * 1998-10-02 2000-04-06 Roehm Gmbh Überzogene Arzneiformen mit kontrollierter Wirkstoffabgabe
EP1027888B1 (en) * 1999-02-10 2009-06-10 Pfizer Products Inc. Osmotic system for delivery of solid amorphous dispersions of drugs
US6706283B1 (en) 1999-02-10 2004-03-16 Pfizer Inc Controlled release by extrusion of solid amorphous dispersions of drugs
US6632451B2 (en) * 1999-06-04 2003-10-14 Dexcel Pharma Technologies Ltd. Delayed total release two pulse gastrointestinal drug delivery system
DK1183014T3 (da) * 1999-06-14 2004-02-09 Cosmo Spa Smagsmaskerede orale farmaceutiske sammensætninger med kontrolleret frigivelse
US20010034340A1 (en) * 2000-03-20 2001-10-25 American Home Products Corporation Hormone replacement therapy

Also Published As

Publication number Publication date
ATE438384T1 (de) 2009-08-15
EP1465602B1 (de) 2009-08-05
CN100542538C (zh) 2009-09-23
CA2470207C (en) 2012-07-10
AU2002361396B2 (en) 2008-02-14
AR037760A1 (es) 2004-12-01
US20050019408A1 (en) 2005-01-27
WO2003051336A1 (de) 2003-06-26
JP2005513059A (ja) 2005-05-12
CN1607943A (zh) 2005-04-20
PL205739B1 (pl) 2010-05-31
JP4695837B2 (ja) 2011-06-08
EP1465602A1 (de) 2004-10-13
AU2002361396A1 (en) 2003-06-30
DK1465602T3 (da) 2009-09-28
MXPA04005769A (es) 2004-09-10
HK1075005A1 (zh) 2005-12-02
TW200408414A (en) 2004-06-01
TWI252111B (en) 2006-04-01
ES2328910T3 (es) 2009-11-19
BR0215044A (pt) 2004-11-03
US8268351B2 (en) 2012-09-18
CA2470207A1 (en) 2003-06-26
PL369367A1 (en) 2005-04-18
SI1465602T1 (sl) 2009-12-31
PT1465602E (pt) 2009-09-07

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