DE4111939A1 - Parenteral verabreichbare, hitzesterilisierbare o/w-emulsion eines roentgenkontrastmittels - Google Patents

Parenteral verabreichbare, hitzesterilisierbare o/w-emulsion eines roentgenkontrastmittels

Info

Publication number
DE4111939A1
DE4111939A1 DE4111939A DE4111939A DE4111939A1 DE 4111939 A1 DE4111939 A1 DE 4111939A1 DE 4111939 A DE4111939 A DE 4111939A DE 4111939 A DE4111939 A DE 4111939A DE 4111939 A1 DE4111939 A1 DE 4111939A1
Authority
DE
Germany
Prior art keywords
emulsion
fatty acid
emulsion according
ray contrast
emulsifiers
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
DE4111939A
Other languages
German (de)
English (en)
Other versions
DE4111939C2 (enrdf_load_stackoverflow
Inventor
Klaus Dr Sommermeyer
Heino Foth
Bernd Eschenbach
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fresenius SE and Co KGaA
Original Assignee
Fresenius SE and Co KGaA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fresenius SE and Co KGaA filed Critical Fresenius SE and Co KGaA
Priority to DE4111939A priority Critical patent/DE4111939A1/de
Priority to IL101231A priority patent/IL101231A0/xx
Priority to CN92101848A priority patent/CN1065595A/zh
Priority to SI9210299A priority patent/SI9210299A/sl
Priority to IE102792A priority patent/IE921027A1/en
Priority to NZ242237A priority patent/NZ242237A/en
Priority to MX9201589A priority patent/MX9201589A/es
Priority to SK1097-93A priority patent/SK109793A3/sk
Priority to PCT/EP1992/000794 priority patent/WO1992018168A1/de
Priority to FI934478A priority patent/FI934478L/fi
Priority to CS931939A priority patent/CZ193993A3/cs
Priority to HU9302863A priority patent/HUT65238A/hu
Priority to CA002101430A priority patent/CA2101430A1/en
Priority to BR9205944A priority patent/BR9205944A/pt
Priority to EP92907897A priority patent/EP0578707A1/de
Priority to AU15362/92A priority patent/AU1536292A/en
Priority to JP4507150A priority patent/JPH06506453A/ja
Priority to ZA922580A priority patent/ZA922580B/xx
Priority to PT100378A priority patent/PT100378A/pt
Publication of DE4111939A1 publication Critical patent/DE4111939A1/de
Application granted granted Critical
Publication of DE4111939C2 publication Critical patent/DE4111939C2/de
Priority to NO933672A priority patent/NO933672L/no
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/04—X-ray contrast preparations
    • A61K49/0433—X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
    • A61K49/0447—Physical forms of mixtures of two different X-ray contrast-enhancing agents, containing at least one X-ray contrast-enhancing agent which is a halogenated organic compound
    • A61K49/0461—Dispersions, colloids, emulsions or suspensions

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
DE4111939A 1991-04-12 1991-04-12 Parenteral verabreichbare, hitzesterilisierbare o/w-emulsion eines roentgenkontrastmittels Granted DE4111939A1 (de)

Priority Applications (20)

Application Number Priority Date Filing Date Title
DE4111939A DE4111939A1 (de) 1991-04-12 1991-04-12 Parenteral verabreichbare, hitzesterilisierbare o/w-emulsion eines roentgenkontrastmittels
IL101231A IL101231A0 (en) 1991-04-12 1992-03-15 Heat-sterilizable oil-in-water emulsion of an x-ray contrast medium for parenteral administration
CN92101848A CN1065595A (zh) 1991-04-12 1992-03-20 非胃肠用药的可加热灭菌的水包油乳剂型x-射线造影剂
SI9210299A SI9210299A (sl) 1991-04-12 1992-03-25 Oljno-vodna emulzija rentgenskega kontrastnega sredstva
IE102792A IE921027A1 (en) 1991-04-12 1992-04-01 Heat-sterilizable oil-in-water emulsion of an x-ray contrast¹medium for parenteral administration
NZ242237A NZ242237A (en) 1991-04-12 1992-04-03 Heat sterilisable x-ray contrast medium for parenteral administration
MX9201589A MX9201589A (es) 1991-04-12 1992-04-07 Emulsion aceite/agua de un medio de contraste roentgenologico, susceptible de ser administrada por via parenteral y de ser esterilizada por medio de calor.
JP4507150A JPH06506453A (ja) 1991-04-12 1992-04-08 Ｘ線造影剤の腸管外適用可能で、加熱滅菌可能な水中油型エマルジョン
FI934478A FI934478L (fi) 1991-04-12 1992-04-08 Parenteralt administrerbar, vaermesteriliserbar o/w-emulsion av ett roentgenkontrastmedel
CS931939A CZ193993A3 (en) 1991-04-12 1992-04-08 Parenterally applicable, heat stabilized emulsion of the oil-in-water emulsion type of x-ray contrast agent
SK1097-93A SK109793A3 (en) 1991-04-12 1992-04-08 Parenterally administrable heat sterilisable o/w emulsions of an x-ray contrast agent
CA002101430A CA2101430A1 (en) 1991-04-12 1992-04-08 Parenterally administrable, heat sterilisable o/w emulsions of an x-ray contrast agent
BR9205944A BR9205944A (pt) 1991-04-12 1992-04-08 Emulsão tipo óleo em água de um agente de contraste de ralos X a base de compostos orgânicos iodados, esterilizável por ação do calor e administrável via parenteral, e processo para a sua preparação
EP92907897A EP0578707A1 (de) 1991-04-12 1992-04-08 Parenteral verabreichbare, hitzesterilisierbare o/w-emulsion eines röntgenkontrastmittels
AU15362/92A AU1536292A (en) 1991-04-12 1992-04-08 Parenterally administrable, heat sterilisable o/w emulsions of an x-ray contrast agent
PCT/EP1992/000794 WO1992018168A1 (de) 1991-04-12 1992-04-08 Parenteral verabreichbare, hitzesterilisierbare o/w-emulsion eines röntgenkontrastmittels
HU9302863A HUT65238A (en) 1991-04-12 1992-04-08 Parenterally administrable, heat sterilisable o/w-emulsions of an x-ray contrast agent
ZA922580A ZA922580B (en) 1991-04-12 1992-04-09 Oil-in-water-emulsion of an x-ray contract medium
PT100378A PT100378A (pt) 1991-04-12 1992-04-10 Emulsao do tipo de oleo em agua de um agente de contraste de raios x a base de compostos organicos iodados, esterizavel por accao do calor, administravel por via parenterica, e processo para a sua preparacao
NO933672A NO933672L (no) 1991-04-12 1993-10-12 Parenteralt tildelbar, varmesteriliserbar O/W-emulsjon for et r!ntgenkontrastmiddel

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4111939A DE4111939A1 (de) 1991-04-12 1991-04-12 Parenteral verabreichbare, hitzesterilisierbare o/w-emulsion eines roentgenkontrastmittels

Publications (2)

Publication Number Publication Date
DE4111939A1 true DE4111939A1 (de) 1992-10-22
DE4111939C2 DE4111939C2 (enrdf_load_stackoverflow) 1993-02-25

Family

ID=6429433

Family Applications (1)

Application Number Title Priority Date Filing Date
DE4111939A Granted DE4111939A1 (de) 1991-04-12 1991-04-12 Parenteral verabreichbare, hitzesterilisierbare o/w-emulsion eines roentgenkontrastmittels

Country Status (19)

Country Link
EP (1) EP0578707A1 (enrdf_load_stackoverflow)
JP (1) JPH06506453A (enrdf_load_stackoverflow)
CN (1) CN1065595A (enrdf_load_stackoverflow)
AU (1) AU1536292A (enrdf_load_stackoverflow)
BR (1) BR9205944A (enrdf_load_stackoverflow)
CA (1) CA2101430A1 (enrdf_load_stackoverflow)
CZ (1) CZ193993A3 (enrdf_load_stackoverflow)
DE (1) DE4111939A1 (enrdf_load_stackoverflow)
FI (1) FI934478L (enrdf_load_stackoverflow)
HU (1) HUT65238A (enrdf_load_stackoverflow)
IE (1) IE921027A1 (enrdf_load_stackoverflow)
IL (1) IL101231A0 (enrdf_load_stackoverflow)
MX (1) MX9201589A (enrdf_load_stackoverflow)
NO (1) NO933672L (enrdf_load_stackoverflow)
NZ (1) NZ242237A (enrdf_load_stackoverflow)
PT (1) PT100378A (enrdf_load_stackoverflow)
SK (1) SK109793A3 (enrdf_load_stackoverflow)
WO (1) WO1992018168A1 (enrdf_load_stackoverflow)
ZA (1) ZA922580B (enrdf_load_stackoverflow)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4316722A1 (de) * 1993-05-19 1994-11-24 Fresenius Ag Parenteral verabreichbare, unter Hitzesterilisationsbedingungen stabile O/W-Emulsion eines Röntgenkontrastmittels

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE470086B (sv) * 1991-04-23 1993-11-08 Kabi Pharmacia Ab Organspecifik emulsion
JP4670229B2 (ja) * 2003-06-10 2011-04-13 味の素株式会社 Ｃｔコロノグラフィにおける消化管造影用組成物
US20140065067A1 (en) * 2010-12-17 2014-03-06 Universite De Strasbourg Radiopaque iodinated products intended for use medical imaging and their methods
JP6578504B2 (ja) * 2013-04-30 2019-09-25 パナソニックＩｐマネジメント株式会社 スクロール圧縮機
CN114288427A (zh) * 2022-03-01 2022-04-08 福建宸润生物科技有限公司 一种肠胃道口服ct造影剂

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1617275B1 (de) * 1966-04-13 1971-05-13 Ab Leo R¦ntgenkontrastmittel
DE2602907C2 (de) * 1976-01-27 1978-03-30 Stephan Dr.Med. 4400 Muenster Roth Röntgenkontrastmittel auf der Basis einer Emulsion von jodierten ölen
US4404182A (en) * 1980-01-08 1983-09-13 The United States Of America As Represented By The Department Of Health And Human Services Ethiodized oil emulsion for intravenous hepatography
EP0294534A1 (en) * 1987-06-11 1988-12-14 Kabi Pharmacia AB Iodine containing emulsion
DE3722540C2 (enrdf_load_stackoverflow) * 1987-07-08 1990-06-13 Fresenius Ag, 6370 Oberursel, De

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR222337A1 (es) * 1978-07-04 1981-05-15 Nyegaard & Co As Procedimiento para preparar una solucion esteril inyectable fisiologicamente aceptable de un agente de contraste de rayos x

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1617275B1 (de) * 1966-04-13 1971-05-13 Ab Leo R¦ntgenkontrastmittel
DE2602907C2 (de) * 1976-01-27 1978-03-30 Stephan Dr.Med. 4400 Muenster Roth Röntgenkontrastmittel auf der Basis einer Emulsion von jodierten ölen
US4404182A (en) * 1980-01-08 1983-09-13 The United States Of America As Represented By The Department Of Health And Human Services Ethiodized oil emulsion for intravenous hepatography
EP0294534A1 (en) * 1987-06-11 1988-12-14 Kabi Pharmacia AB Iodine containing emulsion
DE3722540C2 (enrdf_load_stackoverflow) * 1987-07-08 1990-06-13 Fresenius Ag, 6370 Oberursel, De

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
E. Grimes et al., Journal of Pharmaceutical Science 68 (1979), 52-56 *
J. Reinick et al., Radiology 162 (1987), 43-47 *
M. Vermess et al., J. Comput. Assist. Tomogr. 3 (1979), 25-31 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4316722A1 (de) * 1993-05-19 1994-11-24 Fresenius Ag Parenteral verabreichbare, unter Hitzesterilisationsbedingungen stabile O/W-Emulsion eines Röntgenkontrastmittels
WO1994026316A1 (de) * 1993-05-19 1994-11-24 Fresenius Ag Parenteral verabreichbare, unter hitzesterilisationsbedingungen stabile o/w-emulsion eines röntgenkontrastmittels

Also Published As

Publication number Publication date
BR9205944A (pt) 1994-07-05
PT100378A (pt) 1993-06-30
AU1536292A (en) 1992-11-17
IL101231A0 (en) 1992-11-15
NO933672D0 (no) 1993-10-12
CN1065595A (zh) 1992-10-28
DE4111939C2 (enrdf_load_stackoverflow) 1993-02-25
HU9302863D0 (en) 1993-12-28
WO1992018168A1 (de) 1992-10-29
CZ193993A3 (en) 1994-03-16
NZ242237A (en) 1993-04-28
JPH06506453A (ja) 1994-07-21
ZA922580B (en) 1992-11-25
HUT65238A (en) 1994-05-02
MX9201589A (es) 1992-10-01
IE921027A1 (en) 1992-10-21
FI934478A0 (fi) 1993-10-11
NO933672L (no) 1993-10-12
CA2101430A1 (en) 1992-10-13
SK109793A3 (en) 1994-05-11
FI934478A7 (fi) 1993-10-11
FI934478L (fi) 1993-10-11
EP0578707A1 (de) 1994-01-19

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Legal Events

Date Code Title Description
OP8 Request for examination as to paragraph 44 patent law
D2 Grant after examination
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee