DE3884314D1 - Polymermischung mit umkehrphasen Morphologie zur kontrollierten Wirkstoffabgabe. - Google Patents

Polymermischung mit umkehrphasen Morphologie zur kontrollierten Wirkstoffabgabe.

Info

Publication number
DE3884314D1
DE3884314D1 DE88111876T DE3884314T DE3884314D1 DE 3884314 D1 DE3884314 D1 DE 3884314D1 DE 88111876 T DE88111876 T DE 88111876T DE 3884314 T DE3884314 T DE 3884314T DE 3884314 D1 DE3884314 D1 DE 3884314D1
Authority
DE
Germany
Prior art keywords
drug delivery
reverse phase
polymer blend
controlled drug
phase morphology
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE88111876T
Other languages
English (en)
Other versions
DE3884314T2 (de
Inventor
David Stuart Kashdan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eastman Chemical Co
Original Assignee
Eastman Kodak Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eastman Kodak Co filed Critical Eastman Kodak Co
Publication of DE3884314D1 publication Critical patent/DE3884314D1/de
Application granted granted Critical
Publication of DE3884314T2 publication Critical patent/DE3884314T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7007—Drug-containing films, membranes or sheets
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
    • A01N25/08—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests containing solids as carriers or diluents
    • A01N25/10—Macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L1/00—Compositions of cellulose, modified cellulose or cellulose derivatives
    • C08L1/08—Cellulose derivatives
    • C08L1/10—Esters of organic acids, i.e. acylates
    • C08L1/14—Mixed esters, e.g. cellulose acetate-butyrate

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Agronomy & Crop Science (AREA)
  • Environmental Sciences (AREA)
  • Plant Pathology (AREA)
  • Wood Science & Technology (AREA)
  • Dentistry (AREA)
  • Pest Control & Pesticides (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Artificial Filaments (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE88111876T 1987-08-20 1988-07-23 Polymermischung mit umkehrphasen Morphologie zur kontrollierten Wirkstoffabgabe. Expired - Fee Related DE3884314T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/087,566 US4795641A (en) 1987-08-20 1987-08-20 Polymer blends having reverse phase morphology for controlled delivery of bioactive agents

Publications (2)

Publication Number Publication Date
DE3884314D1 true DE3884314D1 (de) 1993-10-28
DE3884314T2 DE3884314T2 (de) 1994-05-05

Family

ID=22205939

Family Applications (1)

Application Number Title Priority Date Filing Date
DE88111876T Expired - Fee Related DE3884314T2 (de) 1987-08-20 1988-07-23 Polymermischung mit umkehrphasen Morphologie zur kontrollierten Wirkstoffabgabe.

Country Status (5)

Country Link
US (1) US4795641A (de)
EP (1) EP0303853B1 (de)
JP (1) JP2662253B2 (de)
CA (1) CA1319468C (de)
DE (1) DE3884314T2 (de)

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IL90245A (en) * 1988-05-11 1994-04-12 Glaxo Group Ltd Resin adsorption containing ranitidine together with synthetic resin replaces cations, its preparation and pharmaceutical preparations containing it
US4880636A (en) * 1988-05-13 1989-11-14 Franz Robert M Film coated tablet of ranitidine HCl
DE3903247A1 (de) * 1989-02-03 1990-08-09 Shell Int Research Fungizid wirkende zusammensetzung, verfahren zu ihrer herstellung und ihre verwendung, insbesondere zur heilenden behandlung von an pilzerkrankungen leidenden pflanzen
US5229124A (en) * 1990-04-02 1993-07-20 Morton International, Inc. Microbicides immobilized in water soluble thermoplastic resins and aqueous dispersions of microbicides prepared therefrom
US5371211A (en) * 1990-12-04 1994-12-06 Eastman Kodak Company Cellulose esters and salts thereof
WO1992019209A2 (en) * 1991-04-30 1992-11-12 Fmc Corporation Taste-masked medicaments and their preparation
ES2107051T3 (es) * 1992-09-21 1997-11-16 Upjohn Co Formulaciones de proteinas de liberacion sostenida.
US5356634A (en) * 1992-11-13 1994-10-18 Eastman Chemical Company Controlled-release delivery system
US5981719A (en) 1993-03-09 1999-11-09 Epic Therapeutics, Inc. Macromolecular microparticles and methods of production and use
US6090925A (en) 1993-03-09 2000-07-18 Epic Therapeutics, Inc. Macromolecular microparticles and methods of production and use
US6313202B1 (en) * 1993-05-28 2001-11-06 Eastman Chemical Company Cellulose ester blends
US5288318A (en) * 1993-07-01 1994-02-22 The United States Of America As Represented By The Secretary Of The Army Cellulose acetate and starch based biodegradable injection molded plastics compositions and methods of manufacture
US5536505A (en) * 1993-12-15 1996-07-16 Eastman Chemical Company Controlled release matrix system using cellulose acetate/poly-2-ethyl-2-oxazoline blends
US5750119A (en) * 1994-01-13 1998-05-12 Mount Sinai School Of Medicine Of The City University Of New York Immunotherapeutic stress protein-peptide complexes against cancer
DE19622355A1 (de) * 1996-06-04 1997-12-11 Bayer Ag Formkörper die agrochemische Mittel freisetzen
US6734192B1 (en) * 1999-08-23 2004-05-11 Mp-1 Inc. Treatment of viral infections
NZ518281A (en) * 1999-12-23 2005-01-28 Pfizer Prod Inc Controlled release drug dosage core comprising a drug-containing composition and a water-swellable composition
US6929884B2 (en) * 2001-04-19 2005-08-16 Zinc Matrix Power, Inc. Method for manufacture of films containing insoluble solids embedded in cellulose-based films
US20040001889A1 (en) 2002-06-25 2004-01-01 Guohua Chen Short duration depot formulations
EP1545468A4 (de) * 2002-09-20 2007-06-20 Alpharma Inc Opioid-formulierungen mit verz gerter freisetzung und anwendungsverfahren
EP2218448B1 (de) 2002-12-13 2015-09-23 Durect Corporation Orale Darreichungsform mit flüssigen hochviskose Trägersystemen
RS51934B (en) * 2003-08-08 2012-02-29 Biovail Laboratories International Srl. BUPROPION HYDROCHLORIDE TABLE WITH MODIFIED RELEASE
US8627828B2 (en) * 2003-11-07 2014-01-14 U.S. Smokeless Tobacco Company Llc Tobacco compositions
CN102669810B (zh) * 2003-11-07 2014-11-05 美国无烟烟草有限责任公司 烟草组合物
EP1689787A2 (de) 2003-11-28 2006-08-16 Eastman Chemical Company Cellulose-mischpolymere und oxidationsverfahren
CA2581287C (en) * 2004-09-17 2015-08-25 Durect Corporation Sustained local anesthetic composition containing bupivacaine and saib
WO2006082518A1 (en) 2005-02-03 2006-08-10 Pfizer Products Inc. Pharmaceutical compositions with enhanced performance
US20070027105A1 (en) 2005-07-26 2007-02-01 Alza Corporation Peroxide removal from drug delivery vehicle
US20070142804A1 (en) * 2005-12-16 2007-06-21 Bernard Bobby L Hollow-core fibers
AU2007325918B2 (en) 2006-11-03 2013-10-17 Durect Corporation Transdermal delivery systems comprising bupivacaine
US20090036414A1 (en) * 2007-08-02 2009-02-05 Mutual Pharmaceutical Company, Inc. Mesalamine Formulations
JP2011506319A (ja) 2007-12-06 2011-03-03 デュレクト コーポレーション 疼痛、関節炎症状、または慢性疾患に伴う炎症の治療に有用な方法
US20100260844A1 (en) 2008-11-03 2010-10-14 Scicinski Jan J Oral pharmaceutical dosage forms
AU2014233453A1 (en) 2013-03-15 2015-10-01 Durect Corporation Compositions with a rheological modifier to reduce dissolution variability
BR112022013784A2 (pt) 2020-01-13 2022-10-11 Durect Corp Sistemas de distribuição de fármacos de liberação prolongada com impurezas reduzidas e métodos relacionados
WO2023079212A1 (en) * 2021-11-05 2023-05-11 Teknologian Tutkimuskeskus Vtt Oy Bimodal or multimodal cellulose materials and methods for producing such

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4060598A (en) * 1967-06-28 1977-11-29 Boehringer Mannheim G.M.B.H. Tablets coated with aqueous resin dispersions
US3538214A (en) * 1969-04-22 1970-11-03 Merck & Co Inc Controlled release medicinal tablets
EG10802A (en) * 1971-02-19 1976-10-31 Bayer Ag A process for embeding veterinary substances and their protection against the influence of the gastric juice of the rumen
JPS5518694B2 (de) * 1973-04-02 1980-05-21
US4077407A (en) * 1975-11-24 1978-03-07 Alza Corporation Osmotic devices having composite walls
US4177255A (en) * 1977-09-02 1979-12-04 Eastman Kodak Company Rumen-stable pellets
JPS5535031A (en) * 1978-09-04 1980-03-11 Shin Etsu Chem Co Ltd Enteric coating composition
US4503030A (en) * 1983-06-06 1985-03-05 Alza Corporation Device for delivering drug to certain pH environments
JPS6051124A (ja) * 1983-08-31 1985-03-22 Kohjin Co Ltd 腸溶性材コ−ティング液
IE56151B1 (en) * 1983-10-20 1991-05-08 Elan Corp Plc Tablet formulation
US4627850A (en) * 1983-11-02 1986-12-09 Alza Corporation Osmotic capsule
US4610870A (en) * 1984-10-05 1986-09-09 E. R. Squibb & Sons, Inc. Controlled release formulation
US4678516A (en) * 1984-10-09 1987-07-07 The Dow Chemical Company Sustained release dosage form based on highly plasticized cellulose ether gels
DE3524337A1 (de) * 1985-07-08 1987-01-08 Roehm Gmbh Arzneimittelumhuellung

Also Published As

Publication number Publication date
JPS6490231A (en) 1989-04-06
US4795641A (en) 1989-01-03
EP0303853A2 (de) 1989-02-22
JP2662253B2 (ja) 1997-10-08
EP0303853B1 (de) 1993-09-22
DE3884314T2 (de) 1994-05-05
CA1319468C (en) 1993-06-29
EP0303853A3 (en) 1990-11-22

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: EASTMAN CHEMICAL CO., KINGSPORT, TENN., US

8339 Ceased/non-payment of the annual fee