DE3876843T2 - Verfahren zur reinigung des granulocyt-koloniestimulierungsfaktors. - Google Patents

Verfahren zur reinigung des granulocyt-koloniestimulierungsfaktors.

Info

Publication number
DE3876843T2
DE3876843T2 DE8888303757T DE3876843T DE3876843T2 DE 3876843 T2 DE3876843 T2 DE 3876843T2 DE 8888303757 T DE8888303757 T DE 8888303757T DE 3876843 T DE3876843 T DE 3876843T DE 3876843 T2 DE3876843 T2 DE 3876843T2
Authority
DE
Germany
Prior art keywords
csf
folded
microorganism
glutathione
solution
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8888303757T
Other languages
German (de)
English (en)
Other versions
DE3876843D1 (de
Inventor
Thomas C Boone
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kirin Brewery Co Ltd
Amgen Inc
Original Assignee
Kirin Brewery Co Ltd
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kirin Brewery Co Ltd, Amgen Inc filed Critical Kirin Brewery Co Ltd
Application granted granted Critical
Publication of DE3876843D1 publication Critical patent/DE3876843D1/de
Publication of DE3876843T2 publication Critical patent/DE3876843T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/53—Colony-stimulating factor [CSF]
    • C07K14/535—Granulocyte CSF; Granulocyte-macrophage CSF
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DE8888303757T 1987-04-28 1988-04-26 Verfahren zur reinigung des granulocyt-koloniestimulierungsfaktors. Expired - Fee Related DE3876843T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US4333187A 1987-04-28 1987-04-28

Publications (2)

Publication Number Publication Date
DE3876843D1 DE3876843D1 (de) 1993-02-04
DE3876843T2 true DE3876843T2 (de) 1993-04-29

Family

ID=21926624

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8888303757T Expired - Fee Related DE3876843T2 (de) 1987-04-28 1988-04-26 Verfahren zur reinigung des granulocyt-koloniestimulierungsfaktors.

Country Status (15)

Country Link
EP (1) EP0289267B1 (en, 2012)
JP (1) JPH0771506B2 (en, 2012)
KR (1) KR960001740B1 (en, 2012)
AT (1) ATE83780T1 (en, 2012)
AU (1) AU621051B2 (en, 2012)
CA (1) CA1302652C (en, 2012)
DE (1) DE3876843T2 (en, 2012)
ES (1) ES2036680T3 (en, 2012)
FI (1) FI94867C (en, 2012)
GR (1) GR3006984T3 (en, 2012)
IL (1) IL86163A (en, 2012)
NO (1) NO175638C (en, 2012)
NZ (1) NZ224371A (en, 2012)
WO (1) WO1988008428A1 (en, 2012)
ZA (1) ZA882808B (en, 2012)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4929700A (en) * 1987-04-16 1990-05-29 Cetus Corporation Production of purified, biologically active, bacterially produced recombinant human CSF-1
CA1339757C (en) 1987-04-16 1998-03-17 Robert F. Halenbeck Production of purified biologically active, bacterially produced recombinant human csf-1
EP0719860B1 (en) * 1988-05-13 2009-12-16 Amgen Inc. Process for isolating and purifying G-CSF
JP2517100B2 (ja) * 1989-03-08 1996-07-24 協和醗酵工業株式会社 ヒト顆粒球コロニ―刺激因子活性を有する蛋白質の精製法
GB9107846D0 (en) * 1990-04-30 1991-05-29 Ici Plc Polypeptides
US6911204B2 (en) 2000-08-11 2005-06-28 Favrille, Inc. Method and composition for altering a B cell mediated pathology
US8161889B2 (en) 2006-11-16 2012-04-24 Mitsubishi Heavy Industries, Ltd. Bogie structure for a track vehicle

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GR79124B (en, 2012) * 1982-12-22 1984-10-02 Genentech Inc
US4530787A (en) * 1984-03-28 1985-07-23 Cetus Corporation Controlled oxidation of microbially produced cysteine-containing proteins
CN1031465C (zh) * 1984-11-20 1996-04-03 先灵生物技术公司 编码表现有人粒细胞巨口噬细胞和嗜伊红细胞生长因子活性多之肽cDNA克隆
GB8508340D0 (en) * 1985-03-29 1985-05-09 Creighton T E Production of protein
US4748234A (en) * 1985-06-26 1988-05-31 Cetus Corporation Process for recovering refractile bodies containing heterologous proteins from microbial hosts
DE3537708A1 (de) * 1985-10-23 1987-04-23 Boehringer Mannheim Gmbh Verfahren zur aktivierung von t-pa nach expression in prokaryonten
US4734362A (en) * 1986-02-03 1988-03-29 Cambridge Bioscience Corporation Process for purifying recombinant proteins, and products thereof

Also Published As

Publication number Publication date
EP0289267B1 (en) 1992-12-23
KR890701616A (ko) 1989-12-21
KR960001740B1 (en) 1996-02-05
NO175638C (no) 1994-11-09
NZ224371A (en) 1990-11-27
CA1302652C (en) 1992-06-02
EP0289267A2 (en) 1988-11-02
EP0289267A3 (en) 1989-11-08
ZA882808B (en) 1988-10-20
JPS6427492A (en) 1989-01-30
ATE83780T1 (de) 1993-01-15
IL86163A (en) 1992-11-15
DE3876843D1 (de) 1993-02-04
AU1711588A (en) 1988-12-02
WO1988008428A1 (en) 1988-11-03
NO175638B (en, 2012) 1994-08-01
AU621051B2 (en) 1992-03-05
GR3006984T3 (en, 2012) 1993-06-30
ES2036680T3 (es) 1993-06-01
NO885777D0 (no) 1988-12-27
FI885986L (fi) 1988-12-27
NO885777L (no) 1988-12-27
JPH0771506B2 (ja) 1995-08-02
FI94867C (fi) 1995-11-10
FI94867B (fi) 1995-07-31
IL86163A0 (en) 1988-11-15

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee