DE3856297D1 - Amorphe Form von Aztreonam - Google Patents

Amorphe Form von Aztreonam

Info

Publication number
DE3856297D1
DE3856297D1 DE3856297T DE3856297T DE3856297D1 DE 3856297 D1 DE3856297 D1 DE 3856297D1 DE 3856297 T DE3856297 T DE 3856297T DE 3856297 T DE3856297 T DE 3856297T DE 3856297 D1 DE3856297 D1 DE 3856297D1
Authority
DE
Germany
Prior art keywords
amorphous form
aztreonam
methylethoxy
ami
imino
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE3856297T
Other languages
English (en)
Other versions
DE3856297T2 (de
Inventor
Sailesh Amilal Varia
George Eugene Reier
James Douglas Pipkin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ER Squibb and Sons LLC
Original Assignee
ER Squibb and Sons LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ER Squibb and Sons LLC filed Critical ER Squibb and Sons LLC
Application granted granted Critical
Publication of DE3856297D1 publication Critical patent/DE3856297D1/de
Publication of DE3856297T2 publication Critical patent/DE3856297T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
DE3856297T 1987-07-01 1988-06-30 Amorphe Form von Aztreonam Expired - Fee Related DE3856297T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US6839287A 1987-07-01 1987-07-01

Publications (2)

Publication Number Publication Date
DE3856297D1 true DE3856297D1 (de) 1999-03-04
DE3856297T2 DE3856297T2 (de) 1999-06-02

Family

ID=22082279

Family Applications (1)

Application Number Title Priority Date Filing Date
DE3856297T Expired - Fee Related DE3856297T2 (de) 1987-07-01 1988-06-30 Amorphe Form von Aztreonam

Country Status (9)

Country Link
EP (1) EP0297580B1 (de)
JP (1) JP2701869B2 (de)
KR (1) KR890002141A (de)
CN (1) CN1028234C (de)
AT (1) ATE175965T1 (de)
CA (1) CA1339136C (de)
DE (1) DE3856297T2 (de)
ES (1) ES2127178T3 (de)
GR (1) GR3029873T3 (de)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IN191492B (de) * 1999-05-25 2003-12-06 Ranbaxy Lab Ltd
EP1415987B1 (de) 2000-10-20 2007-02-28 Eisai R&D Management Co., Ltd. Stickstoff-enthaltende aromatische ringverbindungen zur behandlung von tumorerkrankungen
US7138419B2 (en) 2000-12-27 2006-11-21 Corus Pharma, Inc. Process for manufacturing bulk solutions and a lyophilized pure α-aztreonam lysinate
US7214364B2 (en) 2000-12-27 2007-05-08 Corus Pharma, Inc. Inhalable aztreonam lysinate formulation for treatment and prevention of pulmonary bacterial infections
CA2433280C (en) 2000-12-27 2010-09-21 Salus Pharma, Inc. Inhalable aztreonam for treatment and prevention of pulmonary bacterial infections
WO2004013133A1 (en) 2002-08-05 2004-02-12 TEVA Gyógyszergyár Részvénytársaság Preparation of aztreonam
WO2004052333A1 (en) * 2002-12-11 2004-06-24 Pari Gmbh Pharmaceutical compositions for the pulmonary delivery of aztreonam
JPWO2004080462A1 (ja) 2003-03-10 2006-06-08 エーザイ株式会社 ｃ−Ｋｉｔキナーゼ阻害剤
WO2004103999A1 (en) 2003-05-15 2004-12-02 TEVA Gyógyszergyár Részvénytársaság AZTREONAM β POLYMORPH WITH VERY LOW RESIDUAL SOLVENT CONTENT
AU2004256124B2 (en) * 2003-07-02 2011-04-28 Corus Pharma, Inc. Aztreonam L-lysine and methods for the preparation thereof
BRPI0418200A (pt) 2003-12-25 2007-04-17 Eisai Co Ltd forma cristalina do sal de 4-(3-cloro-4-(ciclopropilaminocarbonila) aminofenóxi)-7-metóxi-6-quinolinacarboxamida ou o solvato do sal e um processo para a sua preparação
EP1797881B1 (de) 2004-09-17 2009-04-15 Eisai R&D Management Co., Ltd. Medizinische zusammensetzung mit verbesserter stabilität und reduzierten gelierungseigenschaften
ES2321336T3 (es) 2005-05-09 2009-06-04 Sicor Inc. Procedimiento para la fabricacion de aztreonam.
US7550483B2 (en) 2005-06-23 2009-06-23 Eisai R&D Management Co., Ltd. Amorphous salt of 4-(3-chloro-4-(cyclopropylaminocarbonyl)aminophenoxy)-7-methoxy-6-quinolinecarboxamide and process for preparing the same
EP1894918A4 (de) * 2005-06-23 2011-06-22 Eisai R&D Man Co Ltd Amorphes salz von 4-(3-chlor-4-(cyclopropylaminocarbonyl)aminophenoxy)-7-methoxy-6-chinolincarboxamid und herstellungsverfahren dafür
EP2281901B1 (de) 2005-08-02 2013-11-27 Eisai R&D Management Co., Ltd. Pharmazeutische anti-tumor Zusammensetzung mit Angiogeneseinhibitoren
EP2036557B1 (de) 2006-05-18 2015-10-21 Eisai R&D Management Co., Ltd. Antitumorales mittel gegen schilddrüsenkrebs
KR101472600B1 (ko) 2006-08-28 2014-12-15 에자이 알앤드디 매니지먼트 가부시키가이샤 미분화형 위암에 대한 항종양제
JP5319306B2 (ja) 2007-01-29 2013-10-16 エーザイ・アール・アンド・ディー・マネジメント株式会社 未分化型胃癌治療用組成物
US8952035B2 (en) 2007-11-09 2015-02-10 Eisai R&D Management Co., Ltd. Combination of anti-angiogenic substance and anti-tumor platinum complex
CN101579336B (zh) * 2009-07-07 2010-06-23 重庆市庆余堂制药有限公司 一种注射用氨曲南及其生产方法
CN102958523B (zh) 2010-06-25 2014-11-19 卫材R&D管理有限公司 使用具有激酶抑制作用的组合的抗肿瘤剂
CN101912356B (zh) * 2010-08-02 2012-01-11 王明 一种氨曲南/精氨酸药物组合物脂微球注射剂
WO2012144463A1 (ja) 2011-04-18 2012-10-26 エーザイ・アール・アンド・ディー・マネジメント株式会社 腫瘍治療剤
US9945862B2 (en) 2011-06-03 2018-04-17 Eisai R&D Management Co., Ltd. Biomarkers for predicting and assessing responsiveness of thyroid and kidney cancer subjects to lenvatinib compounds
BR112015009004A8 (pt) * 2012-12-21 2021-07-20 Eisai R&D Man Co Ltd forma amorfa de derivado de quinolina e método de produção da mesma
MX368099B (es) 2013-05-14 2019-09-19 Eisai R&D Man Co Ltd Biomarcadores para predecir y evaluar el grado de respuesta de sujetos con cancer de endometrio a compuestos de tipo lenvatinib.
HRP20221047T1 (hr) 2014-08-28 2022-11-11 Eisai R&D Management Co., Ltd. Derivat kinolina visoke čistoće i postupak za njegovu proizvodnju
CN107427505A (zh) 2015-02-25 2017-12-01 卫材R&D管理有限公司 用于抑制喹啉衍生物的苦味的方法
WO2016140717A1 (en) 2015-03-04 2016-09-09 Merck Sharp & Dohme Corp. Combination of a pd-1 antagonist and a vegfr/fgfr/ret tyrosine kinase inhibitor for treating cancer
US11369623B2 (en) 2015-06-16 2022-06-28 Prism Pharma Co., Ltd. Anticancer combination of a CBP/catenin inhibitor and an immune checkpoint inhibitor

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1181075A (en) * 1981-07-13 1985-01-15 David M. Floyd CRYSTALLINE ANHYDROUS FORM OF [3-S-[3.alpha.(Z),4 .beta.]]-3-[[(2-AMINO-4-THIAZOLYL) [(1-CARBOXY-1-METHYLETHOXY)IMINO]ACETYL] AMINO]-4-METHYL-2-OXO-1-AZETIDINESULFONIC ACID
YU44680B (en) * 1982-07-30 1990-12-31 Glaxo Lab Ltd Process for obtaining very pure amorphous form of cephuroxim axetile

Also Published As

Publication number Publication date
EP0297580A1 (de) 1989-01-04
ATE175965T1 (de) 1999-02-15
EP0297580B1 (de) 1999-01-20
DE3856297T2 (de) 1999-06-02
GR3029873T3 (en) 1999-07-30
CA1339136C (en) 1997-07-29
CN1028234C (zh) 1995-04-19
ES2127178T3 (es) 1999-04-16
CN1030238A (zh) 1989-01-11
JPS6422874A (en) 1989-01-25
JP2701869B2 (ja) 1998-01-21
KR890002141A (ko) 1989-04-08

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee