DE3853825D1 - Ionophore als reagenz zur bestimmung von ionen. - Google Patents
Ionophore als reagenz zur bestimmung von ionen.Info
- Publication number
- DE3853825D1 DE3853825D1 DE3853825T DE3853825T DE3853825D1 DE 3853825 D1 DE3853825 D1 DE 3853825D1 DE 3853825 T DE3853825 T DE 3853825T DE 3853825 T DE3853825 T DE 3853825T DE 3853825 D1 DE3853825 D1 DE 3853825D1
- Authority
- DE
- Germany
- Prior art keywords
- ionophores
- fused
- ions
- ion
- dimensional
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 239000002555 ionophore Substances 0.000 title abstract 4
- 230000000236 ionophoric effect Effects 0.000 title abstract 4
- 150000002500 ions Chemical class 0.000 title abstract 3
- 239000003153 chemical reaction reagent Substances 0.000 title 1
- NLMDJJTUQPXZFG-UHFFFAOYSA-N 1,4,10,13-tetraoxa-7,16-diazacyclooctadecane Chemical compound C1COCCOCCNCCOCCOCCN1 NLMDJJTUQPXZFG-UHFFFAOYSA-N 0.000 abstract 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 abstract 1
- WHXSMMKQMYFTQS-UHFFFAOYSA-N Lithium Chemical compound [Li] WHXSMMKQMYFTQS-UHFFFAOYSA-N 0.000 abstract 1
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 abstract 1
- 239000002739 cryptand Substances 0.000 abstract 1
- 230000007613 environmental effect Effects 0.000 abstract 1
- 125000005842 heteroatom Chemical group 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 229910052744 lithium Inorganic materials 0.000 abstract 1
- 230000007935 neutral effect Effects 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 229910052700 potassium Inorganic materials 0.000 abstract 1
- 239000011591 potassium Substances 0.000 abstract 1
- 229910052708 sodium Inorganic materials 0.000 abstract 1
- 239000011734 sodium Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/08—Bridged systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D498/18—Bridged systems
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Hematology (AREA)
- Engineering & Computer Science (AREA)
- Urology & Nephrology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Biotechnology (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/080,721 US5162525A (en) | 1987-07-31 | 1987-07-31 | Fluorogenic and chromogenic three-dimensional ionophores as selective reagents for detecting ions in biological fluids |
PCT/US1988/002043 WO1989000997A1 (en) | 1987-07-31 | 1988-06-14 | Ionophores as reagents for detecting ions |
Publications (2)
Publication Number | Publication Date |
---|---|
DE3853825D1 true DE3853825D1 (de) | 1995-06-22 |
DE3853825T2 DE3853825T2 (de) | 1995-11-09 |
Family
ID=22159183
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE3853825T Expired - Fee Related DE3853825T2 (de) | 1987-07-31 | 1988-06-14 | Ionophore als reagenz zur bestimmung von ionen. |
Country Status (7)
Country | Link |
---|---|
US (2) | US5162525A (de) |
EP (1) | EP0371992B1 (de) |
JP (1) | JPH0613523B2 (de) |
AT (1) | ATE122677T1 (de) |
CA (1) | CA1305133C (de) |
DE (1) | DE3853825T2 (de) |
WO (1) | WO1989000997A1 (de) |
Families Citing this family (82)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1988008137A1 (en) * | 1987-04-10 | 1988-10-20 | The Flinders University Of South Australia | Determination of ions in fluids |
US5162508A (en) * | 1987-12-18 | 1992-11-10 | Compagnie Oris Industrie | Rare earth cryptates, processes for their preparation, synthesis intermediates and application as fluorescent tracers |
US5154890A (en) * | 1990-11-07 | 1992-10-13 | Hewlett-Packard Company | Fiber optic potassium ion sensor |
US5187103A (en) * | 1991-01-31 | 1993-02-16 | Miles Inc. | Colorimetric method and reagent for the assay of lithium in a test sample |
KR970001146B1 (ko) * | 1993-07-16 | 1997-01-29 | 엘지전자 주식회사 | 가스측정용 바이오센서 및 그 제조방법 |
US5417959A (en) * | 1993-10-04 | 1995-05-23 | Mallinckrodt Medical, Inc. | Functionalized aza-crytand ligands for diagnostic imaging applications |
US5474743A (en) * | 1993-10-21 | 1995-12-12 | Minnesota Mining And Manufacturing Company | Cation-sensing composite structure and compounds for use therein |
US5958782A (en) * | 1993-10-21 | 1999-09-28 | Minnesota Mining And Manufacturing Company | Cation-sensing composite structure and compounds for use therein |
JPH09224724A (ja) * | 1996-02-25 | 1997-09-02 | Masamitsu Suzuki | 指 輪 |
EP0894261B1 (de) | 1996-04-16 | 2005-06-15 | Novartis AG | Kovalent immobilisierte fluorionophore als optische ionensensoren |
AU2384797A (en) | 1996-04-18 | 1997-11-12 | Novartis Ag | Fluoroionophores and their use in optical ion sensors |
EP0915865B1 (de) | 1996-07-22 | 2002-02-20 | Novartis AG | Kovalent immobilisierte fluoroionophoren für optische ionen-sensoren |
US5710372A (en) * | 1996-12-17 | 1998-01-20 | Cincinnati Milacron Inc. | Method of analysis for aqueous fluids |
ATE306844T1 (de) * | 1997-02-27 | 2005-11-15 | Terumo Cardiovascular Sys | Kassette zur messung von blut-parametern |
US5997818A (en) * | 1997-02-27 | 1999-12-07 | Minnesota Mining And Manufacturing Company | Cassette for tonometric calibration |
US5822137A (en) * | 1997-02-27 | 1998-10-13 | Minnesota Mining & Manufacturing Co. | Assembly for retaining optical components |
US6009339A (en) | 1997-02-27 | 1999-12-28 | Terumo Cardiovascular Systems Corporation | Blood parameter measurement device |
AT405462B (de) * | 1997-05-30 | 1999-08-25 | Avl List Gmbh | Verfahren zur bestimmung eines alkaliions |
AT405461B (de) * | 1997-05-30 | 1999-08-25 | Avl List Gmbh | Lumineszenzindikator |
US6391005B1 (en) | 1998-03-30 | 2002-05-21 | Agilent Technologies, Inc. | Apparatus and method for penetration with shaft having a sensor for sensing penetration depth |
US6211359B1 (en) | 1999-08-17 | 2001-04-03 | Avl Medical Instruments | Triaza-cryptand and method of determining an alkali ion |
KR100372559B1 (ko) * | 2000-08-14 | 2003-02-17 | 한국전력공사 | 칼륨이온을 선택적으로 흡착하는 새로운 발색성 칼릭스[4]아렌 아자크라운 에테르 유도체 |
US8641644B2 (en) | 2000-11-21 | 2014-02-04 | Sanofi-Aventis Deutschland Gmbh | Blood testing apparatus having a rotatable cartridge with multiple lancing elements and testing means |
US7579463B2 (en) * | 2000-12-20 | 2009-08-25 | Life Technologies Corporation | Crown ether derivatives |
US6962992B2 (en) | 2000-12-20 | 2005-11-08 | Molecullar Probes, Inc. | Crown ether derivatives |
US9427532B2 (en) | 2001-06-12 | 2016-08-30 | Sanofi-Aventis Deutschland Gmbh | Tissue penetration device |
US7316700B2 (en) | 2001-06-12 | 2008-01-08 | Pelikan Technologies, Inc. | Self optimizing lancing device with adaptation means to temporal variations in cutaneous properties |
AU2002348683A1 (en) | 2001-06-12 | 2002-12-23 | Pelikan Technologies, Inc. | Method and apparatus for lancet launching device integrated onto a blood-sampling cartridge |
US7344507B2 (en) | 2002-04-19 | 2008-03-18 | Pelikan Technologies, Inc. | Method and apparatus for lancet actuation |
US7981056B2 (en) | 2002-04-19 | 2011-07-19 | Pelikan Technologies, Inc. | Methods and apparatus for lancet actuation |
US9795747B2 (en) | 2010-06-02 | 2017-10-24 | Sanofi-Aventis Deutschland Gmbh | Methods and apparatus for lancet actuation |
US8337419B2 (en) | 2002-04-19 | 2012-12-25 | Sanofi-Aventis Deutschland Gmbh | Tissue penetration device |
US9226699B2 (en) | 2002-04-19 | 2016-01-05 | Sanofi-Aventis Deutschland Gmbh | Body fluid sampling module with a continuous compression tissue interface surface |
WO2002100460A2 (en) | 2001-06-12 | 2002-12-19 | Pelikan Technologies, Inc. | Electric lancet actuator |
US7041068B2 (en) | 2001-06-12 | 2006-05-09 | Pelikan Technologies, Inc. | Sampling module device and method |
US6660526B2 (en) * | 2001-12-21 | 2003-12-09 | Bayer Corporation | Potassium fluoroionophore |
US8784335B2 (en) | 2002-04-19 | 2014-07-22 | Sanofi-Aventis Deutschland Gmbh | Body fluid sampling device with a capacitive sensor |
US7909778B2 (en) | 2002-04-19 | 2011-03-22 | Pelikan Technologies, Inc. | Method and apparatus for penetrating tissue |
US7547287B2 (en) | 2002-04-19 | 2009-06-16 | Pelikan Technologies, Inc. | Method and apparatus for penetrating tissue |
US9248267B2 (en) | 2002-04-19 | 2016-02-02 | Sanofi-Aventis Deustchland Gmbh | Tissue penetration device |
US9314194B2 (en) | 2002-04-19 | 2016-04-19 | Sanofi-Aventis Deutschland Gmbh | Tissue penetration device |
US7901362B2 (en) | 2002-04-19 | 2011-03-08 | Pelikan Technologies, Inc. | Method and apparatus for penetrating tissue |
US7892185B2 (en) | 2002-04-19 | 2011-02-22 | Pelikan Technologies, Inc. | Method and apparatus for body fluid sampling and analyte sensing |
US7892183B2 (en) | 2002-04-19 | 2011-02-22 | Pelikan Technologies, Inc. | Method and apparatus for body fluid sampling and analyte sensing |
US8579831B2 (en) | 2002-04-19 | 2013-11-12 | Sanofi-Aventis Deutschland Gmbh | Method and apparatus for penetrating tissue |
US7331931B2 (en) | 2002-04-19 | 2008-02-19 | Pelikan Technologies, Inc. | Method and apparatus for penetrating tissue |
US7229458B2 (en) | 2002-04-19 | 2007-06-12 | Pelikan Technologies, Inc. | Method and apparatus for penetrating tissue |
US8221334B2 (en) | 2002-04-19 | 2012-07-17 | Sanofi-Aventis Deutschland Gmbh | Method and apparatus for penetrating tissue |
US7232451B2 (en) | 2002-04-19 | 2007-06-19 | Pelikan Technologies, Inc. | Method and apparatus for penetrating tissue |
US7674232B2 (en) | 2002-04-19 | 2010-03-09 | Pelikan Technologies, Inc. | Method and apparatus for penetrating tissue |
US8267870B2 (en) | 2002-04-19 | 2012-09-18 | Sanofi-Aventis Deutschland Gmbh | Method and apparatus for body fluid sampling with hybrid actuation |
US7976476B2 (en) | 2002-04-19 | 2011-07-12 | Pelikan Technologies, Inc. | Device and method for variable speed lancet |
US7297122B2 (en) | 2002-04-19 | 2007-11-20 | Pelikan Technologies, Inc. | Method and apparatus for penetrating tissue |
US7491178B2 (en) | 2002-04-19 | 2009-02-17 | Pelikan Technologies, Inc. | Method and apparatus for penetrating tissue |
US8360992B2 (en) | 2002-04-19 | 2013-01-29 | Sanofi-Aventis Deutschland Gmbh | Method and apparatus for penetrating tissue |
US8702624B2 (en) | 2006-09-29 | 2014-04-22 | Sanofi-Aventis Deutschland Gmbh | Analyte measurement device with a single shot actuator |
US9795334B2 (en) | 2002-04-19 | 2017-10-24 | Sanofi-Aventis Deutschland Gmbh | Method and apparatus for penetrating tissue |
US7198606B2 (en) | 2002-04-19 | 2007-04-03 | Pelikan Technologies, Inc. | Method and apparatus for a multi-use body fluid sampling device with analyte sensing |
US8574895B2 (en) | 2002-12-30 | 2013-11-05 | Sanofi-Aventis Deutschland Gmbh | Method and apparatus using optical techniques to measure analyte levels |
DE602004028463D1 (de) | 2003-05-30 | 2010-09-16 | Pelikan Technologies Inc | Verfahren und vorrichtung zur injektion von flüssigkeit |
DK1633235T3 (da) | 2003-06-06 | 2014-08-18 | Sanofi Aventis Deutschland | Apparat til udtagelse af legemsvæskeprøver og detektering af analyt |
WO2006001797A1 (en) | 2004-06-14 | 2006-01-05 | Pelikan Technologies, Inc. | Low pain penetrating |
EP1671096A4 (de) | 2003-09-29 | 2009-09-16 | Pelikan Technologies Inc | Verfahren und apparatur für eine verbesserte probeneinfangvorrichtung |
US9351680B2 (en) | 2003-10-14 | 2016-05-31 | Sanofi-Aventis Deutschland Gmbh | Method and apparatus for a variable user interface |
US7822454B1 (en) | 2005-01-03 | 2010-10-26 | Pelikan Technologies, Inc. | Fluid sampling device with improved analyte detecting member configuration |
EP1706026B1 (de) | 2003-12-31 | 2017-03-01 | Sanofi-Aventis Deutschland GmbH | Verfahren und vorrichtung zur verbesserung der fluidströmung und der probennahme |
EP1751546A2 (de) | 2004-05-20 | 2007-02-14 | Albatros Technologies GmbH & Co. KG | Bedruckbares wassergel für biosensoren |
US9775553B2 (en) | 2004-06-03 | 2017-10-03 | Sanofi-Aventis Deutschland Gmbh | Method and apparatus for a fluid sampling device |
WO2005120365A1 (en) | 2004-06-03 | 2005-12-22 | Pelikan Technologies, Inc. | Method and apparatus for a fluid sampling device |
US8652831B2 (en) | 2004-12-30 | 2014-02-18 | Sanofi-Aventis Deutschland Gmbh | Method and apparatus for analyte measurement test time |
US20060240560A1 (en) * | 2005-01-31 | 2006-10-26 | Eric Bakker | Microsphere optical ion sensors based on doped silica gel templates |
US8129365B2 (en) * | 2005-10-11 | 2012-03-06 | The Regents Of The University Of California | Water-soluble, fluorescent compounds for detection of potassium ions |
US8242203B2 (en) * | 2005-11-10 | 2012-08-14 | Eric Bakker | Covalently attached nile blue derivatives for optical sensors |
US7858383B2 (en) * | 2006-05-03 | 2010-12-28 | Opti Medical Systems | Chromoionophore and method of determining sodium ions |
US9279817B2 (en) | 2007-04-13 | 2016-03-08 | Aat Bioquest, Inc. | Carbofluorescein lactone ion indicators and their applications |
US20080254498A1 (en) * | 2007-04-13 | 2008-10-16 | Abd Bioquest, Inc. | Fluorescent ion indicators and their applications |
US9097730B2 (en) | 2007-04-13 | 2015-08-04 | Aat Bioquest, Inc. | Fluorescein lactone ion indicators and their applications |
EP2265324B1 (de) | 2008-04-11 | 2015-01-28 | Sanofi-Aventis Deutschland GmbH | Integriertes System zur Messung von Analyten |
US9375169B2 (en) | 2009-01-30 | 2016-06-28 | Sanofi-Aventis Deutschland Gmbh | Cam drive for managing disposable penetrating member actions with a single motor and motor and control system |
US8965476B2 (en) | 2010-04-16 | 2015-02-24 | Sanofi-Aventis Deutschland Gmbh | Tissue penetration device |
CN102749312B (zh) * | 2012-03-09 | 2014-06-25 | 华东师范大学 | 应用*啶鎓阴离子受体高选择性识别醋酸根离子的方法 |
CN106483111B (zh) * | 2016-09-26 | 2018-11-30 | 华南师范大学 | 芘苯并噻唑席夫碱在检测银离子上的应用 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2842862A1 (de) * | 1978-10-02 | 1980-04-10 | Boehringer Mannheim Gmbh | Verfahren zur bestimmung von ionen, polaren und/oder lipophilen substanzen in fluessigkeiten |
DE3202779A1 (de) * | 1982-01-28 | 1983-08-04 | Merck Patent Gmbh, 6100 Darmstadt | Kaliumreagens und verfahren zur bestimmung von kaliumionen |
CA1222438A (en) * | 1983-05-12 | 1987-06-02 | Steven C. Charlton | Unified test means for ion determination |
US4808539A (en) * | 1987-04-15 | 1989-02-28 | Technicon Instruments Corporation | Compounds, reagents and procedures for determining cations |
US5177221A (en) * | 1987-04-15 | 1993-01-05 | Miles Inc. | Chromogenic hemispherands and their preparation |
-
1987
- 1987-07-31 US US07/080,721 patent/US5162525A/en not_active Expired - Lifetime
-
1988
- 1988-06-14 DE DE3853825T patent/DE3853825T2/de not_active Expired - Fee Related
- 1988-06-14 WO PCT/US1988/002043 patent/WO1989000997A1/en active IP Right Grant
- 1988-06-14 AT AT88906625T patent/ATE122677T1/de not_active IP Right Cessation
- 1988-06-14 JP JP63506400A patent/JPH0613523B2/ja not_active Expired - Fee Related
- 1988-06-14 EP EP88906625A patent/EP0371992B1/de not_active Expired - Lifetime
- 1988-07-21 CA CA000572609A patent/CA1305133C/en not_active Expired - Lifetime
-
1991
- 1991-06-26 US US07/621,510 patent/US5439828A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
JPH0613523B2 (ja) | 1994-02-23 |
EP0371992A1 (de) | 1990-06-13 |
EP0371992B1 (de) | 1995-05-17 |
US5439828A (en) | 1995-08-08 |
WO1989000997A1 (en) | 1989-02-09 |
US5162525A (en) | 1992-11-10 |
ATE122677T1 (de) | 1995-06-15 |
CA1305133C (en) | 1992-07-14 |
DE3853825T2 (de) | 1995-11-09 |
JPH02501481A (ja) | 1990-05-24 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |