DE3851535T2 - Mutanter Stamm von einem methylotrophen Organismus und Verfahren zur Herstellung eines Proteins in methylotrophen Organismus. - Google Patents

Mutanter Stamm von einem methylotrophen Organismus und Verfahren zur Herstellung eines Proteins in methylotrophen Organismus.

Info

Publication number
DE3851535T2
DE3851535T2 DE3851535T DE3851535T DE3851535T2 DE 3851535 T2 DE3851535 T2 DE 3851535T2 DE 3851535 T DE3851535 T DE 3851535T DE 3851535 T DE3851535 T DE 3851535T DE 3851535 T2 DE3851535 T2 DE 3851535T2
Authority
DE
Germany
Prior art keywords
methylotrophic
expression
protein
organism
methanol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE3851535T
Other languages
English (en)
Other versions
DE3851535D1 (de
Inventor
Rainer O Dr Roggenkampe
Zbigniew A Dr Janowicz
Cornelis P Prof Dr Hollenberg
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Dynavax GmbH
Original Assignee
Rhein Biotech GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhein Biotech GmbH filed Critical Rhein Biotech GmbH
Publication of DE3851535D1 publication Critical patent/DE3851535D1/de
Application granted granted Critical
Publication of DE3851535T2 publication Critical patent/DE3851535T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • C12N15/815—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts for yeasts other than Saccharomyces

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
DE3851535T 1988-12-20 1988-12-20 Mutanter Stamm von einem methylotrophen Organismus und Verfahren zur Herstellung eines Proteins in methylotrophen Organismus. Expired - Fee Related DE3851535T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP88121327A EP0374282B1 (de) 1988-12-20 1988-12-20 Mutanter Stamm von einem methylotrophen Organismus und Verfahren zur Herstellung eines Proteins in methylotrophen Organismus

Publications (2)

Publication Number Publication Date
DE3851535D1 DE3851535D1 (de) 1994-10-20
DE3851535T2 true DE3851535T2 (de) 1995-02-02

Family

ID=8199690

Family Applications (1)

Application Number Title Priority Date Filing Date
DE3851535T Expired - Fee Related DE3851535T2 (de) 1988-12-20 1988-12-20 Mutanter Stamm von einem methylotrophen Organismus und Verfahren zur Herstellung eines Proteins in methylotrophen Organismus.

Country Status (5)

Country Link
EP (1) EP0374282B1 (de)
JP (1) JPH02276568A (de)
AT (1) ATE111524T1 (de)
DE (1) DE3851535T2 (de)
ES (1) ES2065331T3 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5204261A (en) * 1991-04-24 1993-04-20 Phillips Petroleum Company Catalase-negative pichia pastoris
CA2101610A1 (en) * 1992-08-07 1994-02-08 William D. Prevatt Production of bacillus entomotoxins in methylotrophic yeast
JPH06209763A (ja) * 1993-01-13 1994-08-02 Green Cross Corp:The 変異株

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1341130C (en) * 1984-07-27 2000-10-31 Adrianus Marinus Ledeboer Use of oxidoreductases in bleaching and/or detergent compositions and their preparation by microorganisms engineered by recombinant dna technology
US4855231A (en) * 1984-10-30 1989-08-08 Phillips Petroleum Company Regulatory region for heterologous gene expression in yeast
ATE58169T1 (de) * 1986-11-24 1990-11-15 Unilever Nv Verfahren zur herstellung einer catalasefreien, oxidase enthaltenden hefe und deren verwendung.

Also Published As

Publication number Publication date
JPH02276568A (ja) 1990-11-13
DE3851535D1 (de) 1994-10-20
ES2065331T3 (es) 1995-02-16
ATE111524T1 (de) 1994-09-15
EP0374282B1 (de) 1994-09-14
EP0374282A1 (de) 1990-06-27

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee