DE384587C - Process for the preparation of alkali silicate solutions intended for intravenous treatment - Google Patents
Process for the preparation of alkali silicate solutions intended for intravenous treatmentInfo
- Publication number
- DE384587C DE384587C DEK84713D DEK0084713D DE384587C DE 384587 C DE384587 C DE 384587C DE K84713 D DEK84713 D DE K84713D DE K0084713 D DEK0084713 D DE K0084713D DE 384587 C DE384587 C DE 384587C
- Authority
- DE
- Germany
- Prior art keywords
- alkali silicate
- preparation
- intravenous treatment
- silicate solutions
- solutions intended
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Inorganic Chemistry (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Description
Verfahren zur Herstellung von zur intravenösen Behandlung bestimmten Alkalisilikatlösungen. Die bislang zur intravenösen Behandlung von Herzkrankheiten, Asthma und Lungentuberkulose benutzte einprozentige Natriumsilikatlösung ist infolge ihres Gehaltes an freiem Alkali nicht in größerer Menge verwendbar.Process for the manufacture of products intended for intravenous treatment Alkali silicate solutions. The previously used intravenous treatment of heart disease, One percent sodium silicate solution used for asthma and pulmonary tuberculosis is owing Their free alkali content cannot be used in large quantities.
Versucht man sie durch eine indifferente Säure zu neutralisieren, so fällt die Kieselsäure entsprechend ihrem Charakter als schwächere Säure bald als Gel aus, so daß derartige Lösungen nicht haltbar sind.If you try to neutralize it with an indifferent acid, so the silica soon falls, according to its character as a weaker acid as a gel, so that such solutions are not stable.
Durch einen genau dosierten Zusatz von zehnprozentiger alkoholischer Jodlösung (25 ccm Jodlösung auf 300 ccm einprozentige Natriumsilikatlösung), wobei in der Wärme das überschüssige Natron zum Jod übergeht (Bildung von jodsaurem Natrium und Jodnatrium), wird die Alkaleszenz ganz erheblich herabgesetzt, ohne daß die Kieselsäure in die Gelform übergeht.With a precisely dosed addition of ten percent alcoholic iodine solution (25 ccm iodine solution to 300 ccm one percent sodium silicate solution), with the excess sodium being converted to iodine in the warmth (formation of sodium iodic acid and sodium iodine), the alkalescence is considerably reduced, without the silicic acid goes into gel form.
Es ergibt sich nun eine dauernd haltbare Kieselsäure-Jod-Lösung von. geringem Alkaligehalt, die ohne Schaden selbst in größerer Menge in die Vene eingespritzt werden kann.The result is a permanently stable silica-iodine solution of. low alkali, injected into the vein in large quantities without harm can be.
Das Mittel hat sich in der Praxis schon hervorragend bei der Behandlung von Herzerkrankungen, Aderverkalkungen, Bronchialasthma und Lungentuberkulose bewährt.In practice, the remedy has already proven to be excellent in treatment Proven against heart disease, calcification of the veins, bronchial asthma and pulmonary tuberculosis.
Das Problem der reizlosen intravenösen Kieselsäureverabfolgung ist damit gelöst, nachdem- alle bisherigen kolloidalen und wäßrigen hochdispersen Kieselsäurelösungen vom Körper nicht reaktionslos vertragen wurden.The problem with non-irritating intravenous silica administration is thus solved after all previous colloidal and aqueous highly disperse silica solutions were not tolerated by the body without reaction.
Claims (1)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DEK84713D DE384587C (en) | 1923-01-25 | 1923-01-25 | Process for the preparation of alkali silicate solutions intended for intravenous treatment |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DEK84713D DE384587C (en) | 1923-01-25 | 1923-01-25 | Process for the preparation of alkali silicate solutions intended for intravenous treatment |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE384587C true DE384587C (en) | 1923-11-03 |
Family
ID=7235161
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DEK84713D Expired DE384587C (en) | 1923-01-25 | 1923-01-25 | Process for the preparation of alkali silicate solutions intended for intravenous treatment |
Country Status (1)
| Country | Link |
|---|---|
| DE (1) | DE384587C (en) |
-
1923
- 1923-01-25 DE DEK84713D patent/DE384587C/en not_active Expired
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