DE3787315D1 - Menschliches Protein-S, ein Plasmaprotein, das die Blutgerinnung reguliert. - Google Patents

Menschliches Protein-S, ein Plasmaprotein, das die Blutgerinnung reguliert.

Info

Publication number
DE3787315D1
DE3787315D1 DE87304676T DE3787315T DE3787315D1 DE 3787315 D1 DE3787315 D1 DE 3787315D1 DE 87304676 T DE87304676 T DE 87304676T DE 3787315 T DE3787315 T DE 3787315T DE 3787315 D1 DE3787315 D1 DE 3787315D1
Authority
DE
Germany
Prior art keywords
protein
blood clotting
regulates blood
plasma
human
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE87304676T
Other languages
English (en)
Other versions
DE3787315T2 (de
Inventor
Jo Ann Hoskins
George Louis Long
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Application granted granted Critical
Publication of DE3787315D1 publication Critical patent/DE3787315D1/de
Publication of DE3787315T2 publication Critical patent/DE3787315T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Hematology (AREA)
  • Toxicology (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE87304676T 1986-05-27 1987-05-27 Menschliches Protein-S, ein Plasmaprotein, das die Blutgerinnung reguliert. Expired - Fee Related DE3787315T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US86666286A 1986-05-27 1986-05-27

Publications (2)

Publication Number Publication Date
DE3787315D1 true DE3787315D1 (de) 1993-10-14
DE3787315T2 DE3787315T2 (de) 1994-02-03

Family

ID=25348099

Family Applications (1)

Application Number Title Priority Date Filing Date
DE87304676T Expired - Fee Related DE3787315T2 (de) 1986-05-27 1987-05-27 Menschliches Protein-S, ein Plasmaprotein, das die Blutgerinnung reguliert.

Country Status (8)

Country Link
EP (1) EP0247843B1 (de)
JP (1) JP2557385B2 (de)
AU (1) AU600944B2 (de)
CA (1) CA1338260C (de)
DE (1) DE3787315T2 (de)
DK (1) DK171825B1 (de)
IE (1) IE60641B1 (de)
IL (1) IL82648A0 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH03501921A (ja) * 1987-05-18 1991-05-09 インテグレイテッド・ジェネティクス・インク 改良タンパク質分子、並びにその製造及び活性化方法
JP5662149B2 (ja) 2008-08-13 2015-01-28 協和発酵キリン株式会社 遺伝子組換えプロテインｓ組成物

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3504172A1 (de) * 1985-02-07 1986-08-07 Henkel KGaA, 4000 Düsseldorf Wirkstoffkonzentrate fuer alkalische zweikomponentenreiniger, verfahren zu ihrer herstellung und ihre verwendung
GR860984B (en) * 1985-04-17 1986-08-18 Zymogenetics Inc Expression of factor vii and ix activities in mammalian cells
US5258288A (en) * 1986-07-25 1993-11-02 Genzyme Corporation Vector containing DNA encoding mature human protein S

Also Published As

Publication number Publication date
DK266187A (da) 1987-11-28
IE60641B1 (en) 1994-07-27
AU600944B2 (en) 1990-08-30
CA1338260C (en) 1996-04-23
DK171825B1 (da) 1997-06-23
JPS62289199A (ja) 1987-12-16
DK266187D0 (da) 1987-05-26
AU7340487A (en) 1987-12-03
DE3787315T2 (de) 1994-02-03
EP0247843A3 (en) 1989-02-01
EP0247843A2 (de) 1987-12-02
IL82648A0 (en) 1987-11-30
IE871369L (en) 1987-11-27
JP2557385B2 (ja) 1996-11-27
EP0247843B1 (de) 1993-09-08

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee