DE3786174D1 - Weiche steroide mit anti-entzuendungswirkung. - Google Patents

Weiche steroide mit anti-entzuendungswirkung.

Info

Publication number
DE3786174D1
DE3786174D1 DE8787907186T DE3786174T DE3786174D1 DE 3786174 D1 DE3786174 D1 DE 3786174D1 DE 8787907186 T DE8787907186 T DE 8787907186T DE 3786174 T DE3786174 T DE 3786174T DE 3786174 D1 DE3786174 D1 DE 3786174D1
Authority
DE
Germany
Prior art keywords
alkyl
substd
opt
phenyl
beta
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8787907186T
Other languages
English (en)
Other versions
DE3786174T2 (de
Inventor
Nicholas S Bodor
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of DE3786174D1 publication Critical patent/DE3786174D1/de
Application granted granted Critical
Publication of DE3786174T2 publication Critical patent/DE3786174T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C07J31/006—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J21/005—Ketals
    • C07J21/006—Ketals at position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J3/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom
    • C07J3/005—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom the carbon atom being part of a carboxylic function

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
DE87907186T 1987-10-13 1987-10-13 Weiche steroide mit anti-entzündungswirkung. Expired - Fee Related DE3786174T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PCT/US1987/002590 WO1989003390A1 (en) 1987-10-13 1987-10-13 Soft steroids having anti-inflammatory activity
EP87907186A EP0334853B1 (de) 1987-10-13 1987-10-13 Weiche steroide mit anti-entzündungswirkung

Publications (2)

Publication Number Publication Date
DE3786174D1 true DE3786174D1 (de) 1993-07-15
DE3786174T2 DE3786174T2 (de) 1993-10-21

Family

ID=22202600

Family Applications (1)

Application Number Title Priority Date Filing Date
DE87907186T Expired - Fee Related DE3786174T2 (de) 1987-10-13 1987-10-13 Weiche steroide mit anti-entzündungswirkung.

Country Status (4)

Country Link
EP (1) EP0334853B1 (de)
AT (1) ATE90355T1 (de)
DE (1) DE3786174T2 (de)
WO (1) WO1989003390A1 (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4018168A1 (de) * 1990-06-01 1991-12-05 Schering Ag Ausgangsverbindungen fuer die herstellung von 10ss-h-steroiden und ein verfahren zur herstellung dieser ausgangsverbindungen
US6858596B2 (en) 2000-08-05 2005-02-22 Smithkline Beecham Corporation Formulation containing anti-inflammatory androstane derivative
GB0019172D0 (en) 2000-08-05 2000-09-27 Glaxo Group Ltd Novel compounds
BRPI0113042B8 (pt) 2000-08-05 2021-05-25 Glaxo Group Ltd composto da fórmula ou um seu solvato fisiologicamente aceitável, uso do mesmo, composição farmacêutica, formulação farmacêutica, método para o tratamento de um indivíduo humano ou animal com uma condição inflamatória e/ou alérgica, e, processo para preparar um composto ou um seu solvato
US6777399B2 (en) 2000-08-05 2004-08-17 Smithkline Beecham Corporation Anti-inflammatory androstane derivative compositions
GB2389530B (en) 2002-06-14 2007-01-10 Cipla Ltd Pharmaceutical compositions
CA2496867A1 (en) * 2002-08-28 2004-03-11 Hollis-Eden Pharmaceuticals, Inc. Therapeutic treatment methods
GB0316290D0 (en) * 2003-07-11 2003-08-13 Glaxo Group Ltd Novel compounds
JP2007510723A (ja) * 2003-11-03 2007-04-26 ノートン　ヘルスケアー　リミテッド ドライパウダー吸入器で使用するためのソフトステロイド組成物
US7579335B2 (en) 2005-01-10 2009-08-25 Glaxo Group Limited Androstane 17α-carbonate derivatives for use in the treatment of allergic and inflammatory conditions
PT105723B (pt) * 2011-05-26 2014-03-24 Hovione Farmaci Ncia S A Método para a preparação de compostos orgânicos biologicamente activos
US8900626B2 (en) 2011-06-20 2014-12-02 Senju Usa, Inc. Transdermal drug delivery system and method of using the same
US20150376225A1 (en) * 2013-01-23 2015-12-31 Sphaera Pharma Pvtd. Ltd. Novel compounds of 11beta-hydroxy-steroids for use in mitochondria biogenesis and diseases associated with mitochondrial dysfunction or depletion
WO2016013030A2 (en) 2014-07-23 2016-01-28 Sphaera Pharma Pvt. Ltd. Hydroxysteroid compounds, their intermediates, process of preparation, composition and uses thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3558675A (en) * 1969-06-30 1971-01-26 Merck & Co Inc Steroid carbonates and process
GB1438940A (en) * 1972-07-19 1976-06-09 Glaxo Lab Ltd 17beta-haloalkoxycarbonyl-17alpha-oxysteroids
US4093721A (en) * 1974-08-30 1978-06-06 Glaxo Laboratories Limited Pharmaceutical compositions of 6α,9α-difluoro-androst-4-ene-17β-carboxylates and derivatives thereof
US4263289A (en) * 1978-04-05 1981-04-21 Syntex (U.S.A.) Inc. Thio etianic acid derivatives
SE449106B (sv) * 1980-07-10 1987-04-06 Otsuka Pharma Co Ltd Steroid med anti-inflammatorisk verkan samt komposition innehallande denna

Also Published As

Publication number Publication date
EP0334853B1 (de) 1993-06-09
WO1989003390A1 (en) 1989-04-20
EP0334853A1 (de) 1989-10-04
EP0334853A4 (de) 1990-02-26
ATE90355T1 (de) 1993-06-15
DE3786174T2 (de) 1993-10-21

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee