DE3785967D1 - Monoklonale antikoerper gegen c5a und des-arg74-c5a, ihre herstellung und ihre verwendung. - Google Patents

Monoklonale antikoerper gegen c5a und des-arg74-c5a, ihre herstellung und ihre verwendung.

Info

Publication number
DE3785967D1
DE3785967D1 DE8787303762T DE3785967T DE3785967D1 DE 3785967 D1 DE3785967 D1 DE 3785967D1 DE 8787303762 T DE8787303762 T DE 8787303762T DE 3785967 T DE3785967 T DE 3785967T DE 3785967 D1 DE3785967 D1 DE 3785967D1
Authority
DE
Germany
Prior art keywords
arg74
des
production
monoclonal antibodies
antibodies against
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8787303762T
Other languages
English (en)
Other versions
DE3785967T2 (de
Inventor
James W Larrick
Brian M Fendly
Tracey E Deinhart
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis Vaccines and Diagnostics Inc
Original Assignee
Cetus Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cetus Corp filed Critical Cetus Corp
Publication of DE3785967D1 publication Critical patent/DE3785967D1/de
Application granted granted Critical
Publication of DE3785967T2 publication Critical patent/DE3785967T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DE87303762T 1986-04-28 1987-04-28 Monoklonale Antikörper gegen C5A und DES-ARG74-C5A, ihre Herstellung und ihre Verwendung. Expired - Fee Related DE3785967T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US85678086A 1986-04-28 1986-04-28
US94783986A 1986-12-30 1986-12-30

Publications (2)

Publication Number Publication Date
DE3785967D1 true DE3785967D1 (de) 1993-07-01
DE3785967T2 DE3785967T2 (de) 1993-12-02

Family

ID=27127377

Family Applications (1)

Application Number Title Priority Date Filing Date
DE87303762T Expired - Fee Related DE3785967T2 (de) 1986-04-28 1987-04-28 Monoklonale Antikörper gegen C5A und DES-ARG74-C5A, ihre Herstellung und ihre Verwendung.

Country Status (4)

Country Link
EP (1) EP0245993B1 (de)
JP (2) JP2703764B2 (de)
DE (1) DE3785967T2 (de)
ES (1) ES2054667T3 (de)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113416254A (zh) * 2014-03-07 2021-09-21 瑞颂医药公司 具有改善的药物动力学的抗c5抗体

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO162210C (no) * 1987-07-20 1989-11-22 Fasting Biotech As Monoklonale antistoffer mot c5a for in-vitro anvendelse ved immunologiske kvantitative teknikker eller ved isolering av c5a.
DE3924924A1 (de) * 1989-07-27 1991-02-07 Goetze Otto Verfahren zum nachweis und/oder der quantitativen bestimmung von komplementpeptid c5a und/oder c5adesarg
US5837499A (en) * 1993-12-06 1998-11-17 Ciba-Geigy Corporation DNA encoding C5A receptor antagonists having substantially no agonist activity and methods of expressing same
CN1142854A (zh) * 1993-12-06 1997-02-12 西巴-盖尔基股份公司 基本上不具有激动剂活性的C5a受体拮抗剂
US5807824A (en) * 1993-12-06 1998-09-15 Ciba-Geigy Corporation C5A receptor antagonists having substantially no agonist activity
AU3729295A (en) 1994-09-23 1996-04-09 Alexion Pharmaceuticals, Inc. Methods for the treatment of inflammatory joint disease
US6673346B1 (en) 1999-08-31 2004-01-06 The Regents Of The University Of Michigan Compositions and methods for the treatment of sepsis
US7432356B2 (en) 2001-08-17 2008-10-07 Genentech, Inc. Complement pathway inhibitors binding to C5 and C5a without preventing formation of C5b
AU2003290605A1 (en) * 2002-11-05 2004-06-03 The Regents Of The University Of Michigan Compositions and methods for the diagnosis and treatment of sepsis
AU2004241069B2 (en) 2003-05-15 2010-09-09 Genentech, Inc. Methods and compositions for the prevention and treatment of sepsis
CA2797856C (en) * 2010-04-30 2018-09-18 Alexion Pharmaceuticals, Inc. Anti-c5a antibodies and methods for using the antibodies
ES2784773T3 (es) * 2010-08-06 2020-09-30 Enolcon Gmbh Acumulador de calor de alta temperatura para centrales térmicas de energía solar
EP2468295A1 (de) 2010-12-21 2012-06-27 Affiris AG Impfstoffe basierend auf Komplementprotein C5a Peptide
EP2666785A1 (de) * 2012-05-23 2013-11-27 Affiris AG Auf Komplementfaktor C5a basierender Impfstoff
CA2920666A1 (en) 2013-08-12 2015-02-19 Genentech, Inc. Compositions and method for treating complement-associated conditions
SG11201608868PA (en) 2014-05-01 2016-11-29 Genentech Inc Anti-factor d antibody variants and uses thereof
EP3368090A1 (de) 2015-10-30 2018-09-05 H. Hoffnabb-La Roche Ag Anti-faktor-d-antikörpervarianten-konjugate und verwendungen davon
CN108289951A (zh) 2015-10-30 2018-07-17 豪夫迈·罗氏有限公司 抗-因子d抗体和缀合物
JP6923212B2 (ja) * 2016-02-17 2021-08-18 国立大学法人 東京医科歯科大学 動脈硬化性疾患の発症の予測因子および検査方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0286099A3 (de) * 1983-05-06 1988-12-21 Velos Group Monoklonale Antikörper, die mit Kernendotoxin reagieren

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113416254A (zh) * 2014-03-07 2021-09-21 瑞颂医药公司 具有改善的药物动力学的抗c5抗体

Also Published As

Publication number Publication date
EP0245993A3 (en) 1989-07-26
EP0245993A2 (de) 1987-11-19
DE3785967T2 (de) 1993-12-02
JPH10130167A (ja) 1998-05-19
JP2820402B2 (ja) 1998-11-05
JPS62269699A (ja) 1987-11-24
EP0245993B1 (de) 1993-05-26
JP2703764B2 (ja) 1998-01-26
ES2054667T3 (es) 1994-08-16

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: CHIRON CORP. (N.D.GES.D. STAATES DELAWARE), EMERYV

8339 Ceased/non-payment of the annual fee