DE3780179D1 - Herstellung von menschlichem erythropoietin. - Google Patents

Herstellung von menschlichem erythropoietin.

Info

Publication number
DE3780179D1
DE3780179D1 DE8787300399T DE3780179T DE3780179D1 DE 3780179 D1 DE3780179 D1 DE 3780179D1 DE 8787300399 T DE8787300399 T DE 8787300399T DE 3780179 T DE3780179 T DE 3780179T DE 3780179 D1 DE3780179 D1 DE 3780179D1
Authority
DE
Germany
Prior art keywords
cells
gene
human
plasmid
namalwa
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8787300399T
Other languages
English (en)
Other versions
DE3780179T2 (de
Inventor
Hideki Yanagi
Ikuzo Ogawa
Minoru Okamoto
Tatsunobu Hozumi
Ayuko Soga
Tadahiko Yoshima
Masahiro Tsutsumi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sumitomo Chemical Co Ltd
Original Assignee
Sumitomo Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sumitomo Chemical Co Ltd filed Critical Sumitomo Chemical Co Ltd
Publication of DE3780179D1 publication Critical patent/DE3780179D1/de
Application granted granted Critical
Publication of DE3780179T2 publication Critical patent/DE3780179T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/505—Erythropoietin [EPO]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DE19873780179 1986-01-23 1987-01-19 Herstellung von menschlichem erythropoietin. Expired - Fee Related DE3780179T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP61012868A JPS62171696A (ja) 1986-01-23 1986-01-23 ヒトエリスロポエチンの製造方法

Publications (2)

Publication Number Publication Date
DE3780179D1 true DE3780179D1 (de) 1992-08-13
DE3780179T2 DE3780179T2 (de) 1993-02-04

Family

ID=11817393

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19873780179 Expired - Fee Related DE3780179T2 (de) 1986-01-23 1987-01-19 Herstellung von menschlichem erythropoietin.

Country Status (3)

Country Link
EP (1) EP0232034B1 (de)
JP (1) JPS62171696A (de)
DE (1) DE3780179T2 (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU4104889A (en) * 1988-09-07 1990-03-15 Bioclones (Pty) Ltd Purification of erythropoietin
FR2657880A1 (fr) * 1990-02-02 1991-08-09 Fondation Nale Transfusion San Production de proteines recombinantes a partir de cellules lymphoblastouides humaines et d'heteromyelomes.
DE69131069T2 (de) * 1990-07-13 1999-07-15 Snow Brand Milk Products Co., Ltd., Sapporo, Hokkaido Plasmid das für die aminosäuresequenz von tcf-ii kodierende dns enthalt, transformierte zelle und produktion einer physiologisch aktiven substanz mit ihrer verwendung
US5888774A (en) * 1994-12-19 1999-03-30 Cangene Corporation Recombinant DNA molecules and expression vectors for erythropoietin
US5952226A (en) * 1996-11-05 1999-09-14 Modex Therapeutiques Hypoxia responsive EPO producing cells
US6391633B1 (en) 1997-07-23 2002-05-21 Roche Diagnostics Gmbh Production of erythropoietin by endogenous gene activation
PT1000154E (pt) 1997-07-23 2007-03-30 Roche Diagnostics Gmbh Identificação de linhas celulares humanas para a produção de proteínas humanas por activação endógena de genes
US6548296B1 (en) 1997-07-23 2003-04-15 Roche Diagnostics Gmbh Methods for identifying human cell lines useful for endogenous gene activation, isolated human lines identified thereby, and uses thereof
ES2281133T3 (es) 1997-07-23 2007-09-16 Roche Diagnostics Gmbh Identificacion de lineas celulares humanas para la produccion de proteinas humanas mediante la activacion endogena de genes.
EP0986644B1 (de) * 1997-07-23 2006-10-04 Boehringer Mannheim GmbH Herstellung von erythropoietin durch endogene genaktivierung mit viralen promotoren
EP0984062A1 (de) * 1998-09-04 2000-03-08 Cytos Biotechnology AG Herstellung von menschlichem Erythropoietin
BR9905867A (pt) * 1998-11-06 2001-01-23 Bio Sidus S A Linhagem celular produtora de eritropoietina humana recombinante e a eritropoietina humana recombinante produzida por esta célula
AU2001296354A1 (en) 2000-09-25 2002-04-02 Baylor College Of Medicine Improved system for regulation of transgene expression
CN101062407A (zh) 2006-04-29 2007-10-31 中国科学院上海生命科学研究院 促红细胞生成素在预防或治疗视网膜损伤中的用途
HRP20212024T1 (hr) 2009-05-02 2022-04-01 Genzyme Corporation Genska terapija za neurodegenerativne poremećaje
WO2022159414A1 (en) 2021-01-22 2022-07-28 University Of Rochester Erythropoietin for gastroinfestinal dysfunction

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6045849B2 (ja) * 1980-08-25 1985-10-12 林原 健 ヒトエリトロポエチンの製造方法
NZ210501A (en) * 1983-12-13 1991-08-27 Kirin Amgen Inc Erythropoietin produced by procaryotic or eucaryotic expression of an exogenous dna sequence

Also Published As

Publication number Publication date
JPS62171696A (ja) 1987-07-28
EP0232034B1 (de) 1992-07-08
EP0232034A3 (en) 1988-01-13
DE3780179T2 (de) 1993-02-04
EP0232034A2 (de) 1987-08-12

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Legal Events

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8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee