DE3777986D1 - Lipoxygenase-inhibitor verbindungen. - Google Patents
Lipoxygenase-inhibitor verbindungen.Info
- Publication number
- DE3777986D1 DE3777986D1 DE8787119337T DE3777986T DE3777986D1 DE 3777986 D1 DE3777986 D1 DE 3777986D1 DE 8787119337 T DE8787119337 T DE 8787119337T DE 3777986 T DE3777986 T DE 3777986T DE 3777986 D1 DE3777986 D1 DE 3777986D1
- Authority
- DE
- Germany
- Prior art keywords
- connections
- lipoxygenase inhibitor
- lipoxygenase
- inhibitor
- inhibitor connections
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- G—PHYSICS
- G10—MUSICAL INSTRUMENTS; ACOUSTICS
- G10H—ELECTROPHONIC MUSICAL INSTRUMENTS; INSTRUMENTS IN WHICH THE TONES ARE GENERATED BY ELECTROMECHANICAL MEANS OR ELECTRONIC GENERATORS, OR IN WHICH THE TONES ARE SYNTHESISED FROM A DATA STORE
- G10H2250/00—Aspects of algorithms or signal processing methods without intrinsic musical character, yet specifically adapted for or used in electrophonic musical processing
- G10H2250/055—Filters for musical processing or musical effects; Filter responses, filter architecture, filter coefficients or control parameters therefor
- G10H2250/125—Notch filters
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/582—Recycling of unreacted starting or intermediate materials
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/947,334 US4731382A (en) | 1986-12-29 | 1986-12-29 | Lipoxygenase inhibitory phenylalkanohydroxamic acids |
US07/133,601 US4861798A (en) | 1986-12-29 | 1987-12-22 | Lipoxygenase inhibitory compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
DE3777986D1 true DE3777986D1 (de) | 1992-05-07 |
Family
ID=26831511
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE8787119337T Expired - Fee Related DE3777986D1 (de) | 1986-12-29 | 1987-12-29 | Lipoxygenase-inhibitor verbindungen. |
Country Status (8)
Country | Link |
---|---|
US (1) | US4861798A (de) |
EP (1) | EP0273451B1 (de) |
JP (1) | JPS63264442A (de) |
AU (1) | AU614949B2 (de) |
DE (1) | DE3777986D1 (de) |
ES (1) | ES2041261T3 (de) |
GR (1) | GR3004259T3 (de) |
NZ (1) | NZ223104A (de) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH02196767A (ja) * | 1988-10-11 | 1990-08-03 | Kyowa Hakko Kogyo Co Ltd | ヒドロキサム酸誘導体 |
US5096919A (en) * | 1989-01-05 | 1992-03-17 | Ciba-Geigy Corporation | Pyrrolylphenyl-substituted hydroxamic acid derivatives |
US4960787A (en) * | 1989-02-06 | 1990-10-02 | Ciba-Geigy Corporation | Certain pyrrolyl-substituted hydroxamic acid derivatives |
JP3065636B2 (ja) * | 1989-06-29 | 2000-07-17 | 塩野義製薬株式会社 | [ジ―tert―ブチル(ヒドロキシ)フェニルチオ]置換ヒドロキサム酸誘導体 |
US5093363A (en) * | 1989-08-22 | 1992-03-03 | Shionogi & Co., Ltd. | 2,4,6-substituted phenol derivatives |
US5476873A (en) * | 1990-07-25 | 1995-12-19 | Abbott Laboratories | Acetylene derivatives having lipoxygenase inhibitory activity |
WO1992001682A1 (en) * | 1990-07-25 | 1992-02-06 | Abbott Laboratories | Acetylene derivatives having lipoxygenase inhibitory activity |
US5281623A (en) * | 1990-08-27 | 1994-01-25 | Eli Lilly And Company | Method for treating inflammation |
GB9024820D0 (en) * | 1990-11-15 | 1991-01-02 | Davies Michael J | Pharmaceutical compositions |
US5280046A (en) * | 1991-02-22 | 1994-01-18 | The University Of Colorado Foundation, Inc. | Method of treating type I diabetes |
US5117054A (en) * | 1991-09-26 | 1992-05-26 | Ortho Pharmaceutical Corporation | N-hydroxy, N-methyl propanamides |
US5208364A (en) * | 1992-06-25 | 1993-05-04 | Bristol-Myers Squibb Co. | Antibiotic 5-lipoxygenase inhibitors |
AU7862794A (en) * | 1993-10-19 | 1995-05-08 | Sumitomo Pharmaceuticals Company, Limited | 2,3-diaminopropionic acid derivative |
BR9408174A (pt) * | 1993-11-26 | 1997-05-27 | Pfizer | Compostos isoxazolina como agentes antiinflamatórios |
US5804601A (en) * | 1995-04-10 | 1998-09-08 | Takeda Chemical Industries, Ltd. | Aromatic hydroxamic acid compounds, their production and use |
US6777217B1 (en) * | 1996-03-26 | 2004-08-17 | President And Fellows Of Harvard College | Histone deacetylases, and uses related thereto |
US20030129724A1 (en) | 2000-03-03 | 2003-07-10 | Grozinger Christina M. | Class II human histone deacetylases, and uses related thereto |
CN101495116A (zh) * | 2005-03-22 | 2009-07-29 | 哈佛大学校长及研究员协会 | 蛋白降解病症的治疗 |
CA2642273C (en) | 2006-02-14 | 2016-09-20 | President And Fellows Of Harvard College | Bifunctional histone deacetylase inhibitors |
JP5497431B2 (ja) * | 2006-05-03 | 2014-05-21 | プレジデント アンド フェローズ オブ ハーバード カレッジ | ヒストンデアセチラーゼおよびチューブリンデアセチラーゼ阻害剤 |
JP5309318B2 (ja) * | 2007-03-09 | 2013-10-09 | 国立大学法人 岡山大学 | エステル、カルボン酸及びアミドの製造方法 |
AU2009274549B2 (en) | 2008-07-23 | 2014-05-01 | Dana-Farber Cancer Institute, Inc. | Deacetylase inhibitors and uses thereof |
CN106822080A (zh) | 2009-04-29 | 2017-06-13 | 阿马里纳药物爱尔兰有限公司 | 含有epa和心血管剂的药物组合物以及使用其的方法 |
US8716344B2 (en) | 2009-08-11 | 2014-05-06 | President And Fellows Of Harvard College | Class- and isoform-specific HDAC inhibitors and uses thereof |
CN102526213A (zh) * | 2012-01-31 | 2012-07-04 | 庞树有 | 治疗慢性结肠炎的中药组合物 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2397508A (en) * | 1943-05-29 | 1946-04-02 | Standard Oil Co | Hydroxamic acids |
JPS5946244A (ja) * | 1982-09-09 | 1984-03-15 | Nissan Chem Ind Ltd | ヒドロキサム酸誘導体およびその製造法 |
JPS61118346A (ja) * | 1984-11-12 | 1986-06-05 | Yamanouchi Pharmaceut Co Ltd | ω−(ジヒドロキシフエニル)アルカンカルボン酸誘導体 |
ATE80611T1 (de) * | 1985-03-16 | 1992-10-15 | Wellcome Found | Aryl-derivate. |
US4792560A (en) * | 1985-04-03 | 1988-12-20 | Rorer Pharmaceutical Corporation | Quinoline hydroxamates and their use as modulators of arachidonic acid metabolic pathways |
ZA862476B (en) * | 1985-04-03 | 1986-12-30 | Usv Pharma Corp | Hydroxamates as modulators of arachidonic acid metabolic pathways |
US4604407A (en) * | 1985-04-04 | 1986-08-05 | E. R. Squibb & Sons, Inc. | Hydroxamates |
US4731382A (en) * | 1986-12-29 | 1988-03-15 | Bristol-Myers Company | Lipoxygenase inhibitory phenylalkanohydroxamic acids |
-
1987
- 1987-12-22 US US07/133,601 patent/US4861798A/en not_active Expired - Fee Related
- 1987-12-29 ES ES198787119337T patent/ES2041261T3/es not_active Expired - Lifetime
- 1987-12-29 AU AU83103/87A patent/AU614949B2/en not_active Ceased
- 1987-12-29 EP EP87119337A patent/EP0273451B1/de not_active Expired - Lifetime
- 1987-12-29 DE DE8787119337T patent/DE3777986D1/de not_active Expired - Fee Related
-
1988
- 1988-01-04 JP JP63000242A patent/JPS63264442A/ja active Pending
- 1988-01-06 NZ NZ223104A patent/NZ223104A/en unknown
-
1992
- 1992-04-02 GR GR920400559T patent/GR3004259T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
JPS63264442A (ja) | 1988-11-01 |
AU614949B2 (en) | 1991-09-19 |
AU8310387A (en) | 1988-06-30 |
GR3004259T3 (de) | 1993-03-31 |
EP0273451A2 (de) | 1988-07-06 |
EP0273451B1 (de) | 1992-04-01 |
US4861798A (en) | 1989-08-29 |
EP0273451A3 (en) | 1989-05-03 |
NZ223104A (en) | 1991-05-28 |
ES2041261T3 (es) | 1993-11-16 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |