DE3761138D1 - Nitratderivate und ihre verwendung als gefaesserweiterer. - Google Patents

Nitratderivate und ihre verwendung als gefaesserweiterer.

Info

Publication number
DE3761138D1
DE3761138D1 DE8787400454T DE3761138T DE3761138D1 DE 3761138 D1 DE3761138 D1 DE 3761138D1 DE 8787400454 T DE8787400454 T DE 8787400454T DE 3761138 T DE3761138 T DE 3761138T DE 3761138 D1 DE3761138 D1 DE 3761138D1
Authority
DE
Germany
Prior art keywords
extension
nitrate derivatives
nitrate
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8787400454T
Other languages
English (en)
Inventor
Takahiro Kumonaka
Shigeru Taguchi
Yasushi Green Heights C Suwabe
Toshio Wakabayashi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Terumo Corp
Original Assignee
Terumo Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Terumo Corp filed Critical Terumo Corp
Application granted granted Critical
Publication of DE3761138D1 publication Critical patent/DE3761138D1/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/12—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by halogen atoms or by nitro or nitroso groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/57—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of rings other than six-membered aromatic rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE8787400454T 1986-03-05 1987-03-02 Nitratderivate und ihre verwendung als gefaesserweiterer. Expired - Fee Related DE3761138D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP61048158A JPS62205052A (ja) 1986-03-05 1986-03-05 硝酸エステル誘導体およびこれを含有する血管拡張剤

Publications (1)

Publication Number Publication Date
DE3761138D1 true DE3761138D1 (de) 1990-01-18

Family

ID=12795568

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8787400454T Expired - Fee Related DE3761138D1 (de) 1986-03-05 1987-03-02 Nitratderivate und ihre verwendung als gefaesserweiterer.

Country Status (5)

Country Link
US (1) US4780560A (de)
EP (1) EP0236227B1 (de)
JP (1) JPS62205052A (de)
KR (1) KR900000887B1 (de)
DE (1) DE3761138D1 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4994456A (en) * 1989-03-01 1991-02-19 Nisshin Flour Milling Co., Ltd. Pyridinecarboxylic acid amide derivatives and pharmaceutical compositions comprising same
EP0473027B1 (de) * 1990-08-31 1995-07-26 Nisshin Flour Milling Co., Ltd. Pyridincarbonsäure-Amid-Derivate und diese enthaltende pharmazeutische Zusammensetzungen
IT1256450B (it) * 1992-11-26 1995-12-05 Soldato Piero Del Esteri nitrici con attivita' farmacologica e procedimento per la loro preparazione
US5925658A (en) * 1995-03-02 1999-07-20 Sankyo Company, Limited Optically active thiazolidinone derivative
US20050137191A1 (en) * 1996-06-04 2005-06-23 Thatcher Gregory R. Nitrate esters and their use for mitigating cellular damage
US6310052B1 (en) 1996-06-04 2001-10-30 Queen's University At Kingston Nitrate esters and their use for neurological conditions
US7115661B1 (en) 1999-12-29 2006-10-03 Queen's University At Kingston Methods and compositions for mitigating pain
US20100179192A1 (en) 2007-07-09 2010-07-15 Nicox S.A. Use of nitric oxide releasing compounds in the treatment of chronic pain
CN101928226B (zh) * 2009-07-30 2013-08-21 许景峰 N-(2-羟乙基)阿魏酰胺硝酸酯类化合物及其制备方法
CN102050802B (zh) * 2010-11-10 2013-01-09 许景峰 一种具有抗缺氧药理活性的n-（2-羟乙基）阿魏酰胺硝酸酯衍生物及其制备方法
EP3778559A4 (de) * 2018-04-11 2021-05-12 Mitsubishi Gas Chemical Company, Inc. Verfahren zur herstellung von dicyanoalkan und bis(aminomethyl)alkan

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB906319A (en) * 1959-11-01 1962-09-19 American Cyanamid Co 3,4,5-tri (lower) alkoxycinnamamides and process for preparation
FR2040181A1 (de) * 1969-04-02 1971-01-22 Lipha
JPS5732255A (en) * 1980-08-05 1982-02-20 Kowa Co Trimethoxyphenyl derivative

Also Published As

Publication number Publication date
EP0236227B1 (de) 1989-12-13
KR870008830A (ko) 1987-10-21
EP0236227A1 (de) 1987-09-09
JPS62205052A (ja) 1987-09-09
US4780560A (en) 1988-10-25
KR900000887B1 (ko) 1990-02-17

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee