DE3751513D1 - Nachweis von Viren durch Verstärkung und Hybridisation. - Google Patents

Nachweis von Viren durch Verstärkung und Hybridisation.

Info

Publication number
DE3751513D1
DE3751513D1 DE3751513T DE3751513T DE3751513D1 DE 3751513 D1 DE3751513 D1 DE 3751513D1 DE 3751513 T DE3751513 T DE 3751513T DE 3751513 T DE3751513 T DE 3751513T DE 3751513 D1 DE3751513 D1 DE 3751513D1
Authority
DE
Germany
Prior art keywords
viruses
hybridization
amplification
detection
sequence
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE3751513T
Other languages
English (en)
Other versions
DE3751513T2 (de
Inventor
John Joseph Sninsky
Shirley Lee Kwok
David Henry Mack
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27420125&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE3751513(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of DE3751513D1 publication Critical patent/DE3751513D1/de
Application granted granted Critical
Publication of DE3751513T2 publication Critical patent/DE3751513T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701—Specific hybridization probes
    • C12Q1/706—Specific hybridization probes for hepatitis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701—Specific hybridization probes
    • C12Q1/702—Specific hybridization probes for retroviruses
    • C12Q1/703—Viruses associated with AIDS

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Oncology (AREA)
  • Hospice & Palliative Care (AREA)
  • Communicable Diseases (AREA)
  • AIDS & HIV (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
DE3751513T 1986-01-10 1987-01-09 Nachweis von Viren durch Verstärkung und Hybridisation. Expired - Lifetime DE3751513T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US81812786A 1986-01-10 1986-01-10
US93495586A 1986-11-26 1986-11-26
US93558186A 1986-11-26 1986-11-26

Publications (2)

Publication Number Publication Date
DE3751513D1 true DE3751513D1 (de) 1995-10-19
DE3751513T2 DE3751513T2 (de) 1996-03-28

Family

ID=27420125

Family Applications (1)

Application Number Title Priority Date Filing Date
DE3751513T Expired - Lifetime DE3751513T2 (de) 1986-01-10 1987-01-09 Nachweis von Viren durch Verstärkung und Hybridisation.

Country Status (11)

Country Link
EP (1) EP0229701B1 (de)
JP (2) JP2576980B2 (de)
KR (1) KR910004250B1 (de)
AT (1) ATE127857T1 (de)
AU (1) AU606043B2 (de)
DE (1) DE3751513T2 (de)
DK (1) DK174886B1 (de)
ES (1) ES2078214T3 (de)
IE (1) IE69565B1 (de)
IL (1) IL81219A0 (de)
NZ (1) NZ218865A (de)

Families Citing this family (62)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5386022A (en) * 1985-03-28 1995-01-31 Hoffman-La Roche Inc. Primes and probes for the amplification and detection of aids associated nucleic acids
CA1338457C (en) * 1986-08-22 1996-07-16 Henry A. Erlich Purified thermostable enzyme
US5079351A (en) * 1986-11-26 1992-01-07 Cetus Corporation Oligonucleotides and kits for detection of htlvi and htlvii viruses by hybridization
EP0272098A3 (de) * 1986-12-15 1990-06-06 City Of Hope National Medical Center Verfahren zur Vergrösserung und zum Nachweis von RNS-Sequenzen
IL86724A (en) * 1987-06-19 1995-01-24 Siska Diagnostics Inc Methods and kits for amplification and testing of nucleic acid sequences
US4994368A (en) * 1987-07-23 1991-02-19 Syntex (U.S.A.) Inc. Amplification method for polynucleotide assays
US5273879A (en) * 1987-07-23 1993-12-28 Syntex (U.S.A.) Inc. Amplification method for polynucleotide assays
US6090591A (en) * 1987-07-31 2000-07-18 The Board Of Trustees Of The Leland Stanford Junior University Selective amplification of target polynucleotide sequences
IE72468B1 (en) 1987-07-31 1997-04-09 Univ Leland Stanford Junior Selective amplification of target polynucleotide sequences
US5359100A (en) * 1987-10-15 1994-10-25 Chiron Corporation Bifunctional blocked phosphoramidites useful in making nucleic acid mutimers
US5124246A (en) * 1987-10-15 1992-06-23 Chiron Corporation Nucleic acid multimers and amplified nucleic acid hybridization assays using same
JP2634208B2 (ja) * 1987-11-13 1997-07-23 パイオニア・ハイ―ブレツド・インターナシヨナル・インコーポレイテツド 制限断片長多型性分析方法及びその装置
US4902624A (en) * 1987-11-23 1990-02-20 Eastman Kodak Company Temperature cycling cuvette
FI79342C (fi) * 1987-12-23 1989-12-11 Orion Yhtymae Oy Apparat, del av en apparat och foerfarande foer maongfaldigande av nukleinsyror.
SE8801070D0 (sv) * 1988-03-23 1988-03-23 Pharmacia Ab Method for immobilizing a dna sequence on a solid support
JPH03504199A (ja) * 1988-05-10 1991-09-19 イー・アイ・デユポン・ド・ネモアース・アンド・コンパニー 迅速な核酸検出法
NO165894C (no) * 1988-05-24 1991-04-24 Gunnar Paulsen Analysemetode for gener.
US5389512A (en) * 1988-10-07 1995-02-14 Hoffman-La Roche Inc. Method for determining the relative amount of a viral nucleic acid segment in a sample by the polymerase chain reaction
FR2645173B1 (fr) * 1989-03-29 1994-06-17 Pasteur Institut Clonage et expression de genes codant pour des peptides et/ou des fragments de peptides du virus mokola, application a la preparation d'un v
FR2652091B1 (fr) * 1989-09-20 1994-07-22 Pasteur Institut Sequences nucleotidiques issues du genome des retrovirus du type hiv-1, hiv-2 et siv, et leurs applications notamment pour l'amplification des genomes de ces retrovirus et pour le diagnostic in-vitro des infections dues a ces virus.
US7022814B1 (en) 1992-01-21 2006-04-04 Institut Pasteur And Institut National De La Sante Et De La Recherche Medicale Nucleotide sequences derived from the genome of retroviruses of the HIV-1, HIV-2 and SIV type, and their uses in particular for the amplification of the genomes of these retroviruses and for the in vitro diagnosis of the diseases due to these viruses
CA2585164C (fr) 1989-06-02 2010-02-02 Institut Pasteur Sequences nucleotidiques issues du genome des retrovirus du type hiv-1, hiv-2 et siv, et leurs applications notamment pour l'amplification des genomes de ces retrovirus et pour lediagnostic in vitro des infections dues a ces virus
FR2647809B1 (fr) * 1989-06-02 1991-09-20 Pasteur Institut Amorces oligonucleotidiques pour l'amplification du genome des retrovirus du type hiv-1, hiv-2 et siv, et leurs applications au diagnostic in vitro des infections dues a ces virus
FR2647810B1 (fr) * 1989-06-02 1994-07-22 Pasteur Institut Amorces oligonucleotidiques pour l'amplification du genome des retrovirus du type hiv-2 et siv, et leurs applications au diagnostic in vitro des infections dues a ces virus
IE64040B1 (en) * 1989-06-15 1995-06-28 Akzo Nv Method for determining nucleic acid
FR2648475B1 (fr) * 1989-06-15 1991-09-13 Biotechnologie Ste Europ Procede de recherche et de preparation de sondes chez les pestivirus, oligonucleotides et sondes obtenus et procede de detection des pestivirus
FI95398C (fi) * 1989-06-24 1996-01-25 Boehringer Ingelheim Int Menetelmä ihmisen nuhaviruksen serotyypittämiseksi
DE69034177T2 (de) * 1989-07-11 2005-10-27 Gen-Probe Inc., San Diego Verfahren zur Amplifikation von Nukleinsäuresequenzen
CA2020958C (en) * 1989-07-11 2005-01-11 Daniel L. Kacian Nucleic acid sequence amplification methods
US6589734B1 (en) 1989-07-11 2003-07-08 Gen-Probe Incorporated Detection of HIV
GB8918226D0 (en) * 1989-08-09 1989-09-20 Wellcome Found Dna assays
USRE39282E1 (en) 1989-08-09 2006-09-12 Smithkline Beecham Corporation Nucleic acid derivatives
WO1991002091A1 (en) * 1989-08-10 1991-02-21 Northwestern University Method of identifying herpesviruses and oligonucleotides for use therein
US5196305A (en) * 1989-09-12 1993-03-23 Eastman Kodak Company Diagnostic and amplification methods using primers having thymine at 3' end to overcome primer-target mismatch at the 3' end
EP0435229A1 (de) * 1989-12-27 1991-07-03 Sanwa Kagaku Kenkyusho Co., Ltd. DNS-Gen von einem Non-A Non-B Hepatitis-Virus, seine Klonierung und Verwendung
CA2032203C (en) * 1989-12-29 2009-05-19 Christine L. Brakel Amplification capture assay
US5223414A (en) 1990-05-07 1993-06-29 Sri International Process for nucleic acid hybridization and amplification
IT1249534B (it) * 1990-06-18 1995-02-28 Conbiotec Consorzio Per Le Bio Metodo per la rivelazione specifica di una sequenza nucleotidica bersaglio in un campione di materiale genetico.
US5871910A (en) * 1990-10-31 1999-02-16 Institut Pasteur Probes for the detection of nucleotide sequences implicated in the expression of resistance to glycopeptides, in particular in gram-positive bacteria
FR2668489A1 (fr) * 1990-10-31 1992-04-30 Pasteur Institut Sequences nucleotidiques et polypeptidiques impliquees dans l'expression de la resistance aux glycopeptides. utilisation pour le diagnostic.
FR2677039B1 (fr) * 1991-05-31 1994-09-09 Cis Bio Int Oligonucleotides, utilisables comme reactifs pour la detection in vitro des infections a retrovirus de type hiv et procede de detection de retrovirus de type hiv.
CA2124797C (en) 1991-12-23 2004-03-30 Bruce D. Irvine Hiv probes for use in solution phase sandwich hybridization assays
AU681082B2 (en) * 1992-05-06 1997-08-21 Gen-Probe Incorporated Nucleic acid sequence amplification method, composition and kit
AU683414B2 (en) * 1992-05-06 1997-11-13 Gen-Probe Incorporated Nucleic acid amplification oligonucleotides and probes to human hepatitis B virus
AU4248593A (en) * 1992-05-14 1993-12-13 Mark Holodniy Polymerase chain reaction assays for monitoring antiviral therapy
AU686616B2 (en) 1993-03-26 1998-02-12 Gen-Probe Incorporated Detection of human immunodeficiency virus type 1
US5736334A (en) * 1993-04-12 1998-04-07 Abbott Laboratories Nucleotide sequences and process for amplifying and detection of hepatitis B viral DNA
EP0771320A4 (de) 1993-07-29 1998-11-25 Univ California Lock-polynukleotid das die mhc-ii-expression unterdrückt und verwendung desselben
ZA973367B (en) 1996-04-19 1997-11-18 Innogenetics Nv Method for typing and detecting HBV.
US6143496A (en) 1997-04-17 2000-11-07 Cytonix Corporation Method of sampling, amplifying and quantifying segment of nucleic acid, polymerase chain reaction assembly having nanoliter-sized sample chambers, and method of filling assembly
US6136533A (en) * 1997-07-03 2000-10-24 Id Biomedical Additives for use in cycling probe reactions
US6503709B1 (en) 1997-07-03 2003-01-07 Id Biomedical Corporation Methods for rapidly detecting methicillin resistant staphylococci
US6274316B1 (en) 1997-07-03 2001-08-14 Id Biomedical Corporation Compositions and methods for detecting vancomycin resistant enterococci by cycling probe reactions
JP2002505071A (ja) 1997-11-04 2002-02-19 ロシュ ダイアグノスティックス ゲーエムベーハー 特異的かつ高感度な核酸検出方法
US6579682B1 (en) 1998-03-10 2003-06-17 The Regents Of University Of California Methods and tools for identifying compounds which modulate atherosclerosis by impacting LDL-proteoglycan binding
DE19850186A1 (de) * 1998-10-30 2000-05-25 Roche Diagnostics Gmbh Neue Primer und Sonden zum Nachweis von HIV
DE19921419A1 (de) * 1999-05-08 2000-11-16 Univ Ruprecht Karls Heidelberg Verfahren zum spezifischen Nachweis und zur Identifizierung retroviraler Nukleinsäuren / Retroviren in einem Untersuchungsgut
SG90149A1 (en) * 2000-07-18 2002-07-23 Government Of The Republic Of Diagnostic assay
WO2003064679A2 (en) 2002-01-30 2003-08-07 Id Biomedical Corporation Methods for detecting vancomycin-resistant microorganisms and compositions therefor
KR100460747B1 (ko) * 2002-09-09 2004-12-08 주식회사 바이오메드랩 인체포진 바이러스의 프로브, 이를 이용한 인체포진바이러스의 유전형 분석용 키트 및 유전형 분석방법
AU2004203649B2 (en) 2003-08-12 2006-01-12 F. Hoffmann-La Roche Ag Thermostable Taq polymerase fragment
AU2006246975B2 (en) 2005-05-17 2011-08-11 Ozgene Pty Ltd Sequential cloning system

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0062286A1 (de) * 1981-03-31 1982-10-13 Albert Einstein College Of Medicine Of Yeshiva University Diagnostischer Nachweis von Hepatitis-B-Virus
US4591552A (en) 1982-09-29 1986-05-27 New York Blood Center, Inc. Detection of hepatitis B surface antigen (or antibody to same) with labeled synthetic peptide
JP2539189B2 (ja) * 1983-03-21 1996-10-02 ウエブスター，ジヨン エー．，ジユニヤ 有機体の同定および特徴づけ方法
US4520113A (en) 1984-04-23 1985-05-28 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Serological detection of antibodies to HTLV-III in sera of patients with AIDS and pre-AIDS conditions
US9328391B1 (en) 1984-08-22 2016-05-03 The United States Of America As Represented By The Secretary, Department Of Health And Human Services Cloning and expression of HIV-1 DNA
JPS62500452A (ja) 1984-09-19 1987-02-26 ザ　リ−ジエンツ　オブ　ザ　ユニバ−シテイ　オブ　カリフオルニア ヒト細胞形質転換に関連するレトロウイルスポリペプチド
US4683202A (en) * 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
ES8706823A1 (es) * 1985-03-28 1987-06-16 Cetus Corp Un procedimiento para detectar la presencia o ausencia de al menos una secuencia especifica de acidos nucleicos en una muestra
ZA862335B (en) * 1985-03-28 1987-11-25 Cetus Corp Process for amplifying nucleic acid sequences
US5079351A (en) * 1986-11-26 1992-01-07 Cetus Corporation Oligonucleotides and kits for detection of htlvi and htlvii viruses by hybridization

Also Published As

Publication number Publication date
EP0229701B1 (de) 1995-09-13
JP2574640B2 (ja) 1997-01-22
KR870007427A (ko) 1987-08-19
KR910004250B1 (ko) 1991-06-24
JPH06233700A (ja) 1994-08-23
ES2078214T3 (es) 1995-12-16
DK10787A (da) 1987-07-11
ATE127857T1 (de) 1995-09-15
EP0229701A3 (en) 1990-03-07
DK10787D0 (da) 1987-01-09
AU6710987A (en) 1987-07-16
JP2576980B2 (ja) 1997-01-29
JPS62217161A (ja) 1987-09-24
AU606043B2 (en) 1991-01-31
DE3751513T2 (de) 1996-03-28
EP0229701A2 (de) 1987-07-22
IE870057L (en) 1987-07-10
NZ218865A (en) 1989-05-29
DK174886B1 (da) 2004-01-19
IL81219A0 (en) 1987-08-31
IE69565B1 (en) 1996-10-02

Similar Documents

Publication Publication Date Title
DE3751513D1 (de) Nachweis von Viren durch Verstärkung und Hybridisation.
ES2114850T3 (es) Deteccion de los virus htlvi y htlvii mediante hibridacion.
DE69233083D1 (de) Primers und Sondern zum Nachweis von Hepatitis C
DE69840743D1 (de) Nukleinsäure-primer und -sonden zur detektion von hiv-1 und hiv-2
DE69527392D1 (de) Nachweis von Nukleinsäure-Amplifikation
ATE425259T1 (de) Nachweis von amplifizierten nukleinsäuresequenzen durch bifunktionelle haptenisierung und farbige mikropartikel
DE60041489D1 (de) Nachweis von hiv-1 durch amplifizierung von nukleinsäuren
ATE220726T1 (de) Oligonukleotid-primer für amplifizierung von hcv- nukleinsäure
ATE162226T1 (de) Eliminierung von falschen negativen in nuklein- säuren
DK0417842T3 (da) Diagnose- og amplifikationsfremgangsmåder, der overvinder fejlparring mellem primer og målsekvens på primerens 3-ende
RU92016387A (ru) Молекулярные зонды, способы амплификации
DE69737628D1 (de) Nukleinsäureprimer und -sonden zur detektion onkogener humaner papillomaviren
DK564089A (da) Fremgangsmaade og reagens til paavisning af humant papillomavirus og m-rna
ATE114726T1 (de) Verfahren zum schnellen nachweis von nukleinsäuren.
DE69121821D1 (de) Nukleotid-Sequenzen nützlich als typenspezifische Sonden, PCR Primers und LCR Sonden zur Amplifikation und zum Nachweis von humanem Papillomavirus, sowie dazu verwendete Kits und Verfahren
DE69724487D1 (de) Amplifizierung und Erkennung von Zielnukleinsäuren mit einem nachträglichen Inkubationsschritt
DE59814400D1 (de) Reduktion von Kreuzkontaminationen bei Nukleinsäureamplifikationen
Sninsky et al. Primers and probes for the amplification and detection of AIDS associated nucleic acids
Sninsky et al. Primes and probes for the amplification and detection of aids associated nucleic acids

Legal Events

Date Code Title Description
8363 Opposition against the patent