DE3690488C2 - - Google Patents
Info
- Publication number
- DE3690488C2 DE3690488C2 DE3690488A DE3690488A DE3690488C2 DE 3690488 C2 DE3690488 C2 DE 3690488C2 DE 3690488 A DE3690488 A DE 3690488A DE 3690488 A DE3690488 A DE 3690488A DE 3690488 C2 DE3690488 C2 DE 3690488C2
- Authority
- DE
- Germany
- Prior art keywords
- reagent
- embedding
- feed pump
- containers
- container
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 239000003153 chemical reaction reagent Substances 0.000 claims description 95
- 230000007246 mechanism Effects 0.000 claims description 37
- 210000000078 claw Anatomy 0.000 claims description 12
- 238000002360 preparation method Methods 0.000 claims description 7
- 239000002699 waste material Substances 0.000 description 20
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 18
- 239000011347 resin Substances 0.000 description 10
- 229920005989 resin Polymers 0.000 description 10
- 230000008878 coupling Effects 0.000 description 9
- 238000010168 coupling process Methods 0.000 description 9
- 238000005859 coupling reaction Methods 0.000 description 9
- 239000007788 liquid Substances 0.000 description 9
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 5
- 230000006835 compression Effects 0.000 description 5
- 238000007906 compression Methods 0.000 description 5
- 239000000463 material Substances 0.000 description 5
- 101000793686 Homo sapiens Azurocidin Proteins 0.000 description 4
- 239000000969 carrier Substances 0.000 description 3
- 238000010276 construction Methods 0.000 description 3
- 239000012530 fluid Substances 0.000 description 3
- 238000005470 impregnation Methods 0.000 description 3
- 238000012360 testing method Methods 0.000 description 3
- SXRSQZLOMIGNAQ-UHFFFAOYSA-N Glutaraldehyde Chemical compound O=CCCCC=O SXRSQZLOMIGNAQ-UHFFFAOYSA-N 0.000 description 2
- 239000007789 gas Substances 0.000 description 2
- 238000007654 immersion Methods 0.000 description 2
- 230000008595 infiltration Effects 0.000 description 2
- 238000001764 infiltration Methods 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 230000035515 penetration Effects 0.000 description 2
- 230000008569 process Effects 0.000 description 2
- 235000010678 Paulownia tomentosa Nutrition 0.000 description 1
- 240000002834 Paulownia tomentosa Species 0.000 description 1
- 230000005679 Peltier effect Effects 0.000 description 1
- VMHLLURERBWHNL-UHFFFAOYSA-M Sodium acetate Chemical compound [Na+].CC([O-])=O VMHLLURERBWHNL-UHFFFAOYSA-M 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 239000000853 adhesive Substances 0.000 description 1
- 230000001070 adhesive effect Effects 0.000 description 1
- 229910052782 aluminium Inorganic materials 0.000 description 1
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 229910052799 carbon Inorganic materials 0.000 description 1
- 239000004020 conductor Substances 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 230000018109 developmental process Effects 0.000 description 1
- 230000005284 excitation Effects 0.000 description 1
- 239000004744 fabric Substances 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 238000011835 investigation Methods 0.000 description 1
- 229910052751 metal Inorganic materials 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 238000000386 microscopy Methods 0.000 description 1
- 238000000399 optical microscopy Methods 0.000 description 1
- 238000004382 potting Methods 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 235000017281 sodium acetate Nutrition 0.000 description 1
- 239000001632 sodium acetate Substances 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/36—Embedding or analogous mounting of samples
Landscapes
- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Sampling And Sample Adjustment (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP60206578A JPH0640054B2 (ja) | 1985-09-20 | 1985-09-20 | 電子顕微鏡標本作成用包埋装置 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE3690488C2 true DE3690488C2 (OSRAM) | 1992-03-12 |
Family
ID=16525721
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE19863690488 Pending DE3690488T (OSRAM) | 1985-09-20 | 1986-09-19 | |
| DE3690488A Expired - Fee Related DE3690488C2 (OSRAM) | 1985-09-20 | 1986-09-19 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE19863690488 Pending DE3690488T (OSRAM) | 1985-09-20 | 1986-09-19 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US4834943A (OSRAM) |
| JP (1) | JPH0640054B2 (OSRAM) |
| DE (2) | DE3690488T (OSRAM) |
| GB (1) | GB2189599B (OSRAM) |
| SE (1) | SE460229B (OSRAM) |
| WO (1) | WO1987001803A1 (OSRAM) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5080869A (en) * | 1990-08-14 | 1992-01-14 | Mccormick James B | Apparatus and method for preparing tissue samples for histological examination |
| JPH0465508U (OSRAM) * | 1990-10-13 | 1992-06-08 | ||
| US5304350A (en) * | 1992-01-16 | 1994-04-19 | Kloehn Instrument Inc. | Slide type analytic device, method, and preparation apparatus |
| DE4400815A1 (de) * | 1994-01-13 | 1995-07-20 | Mls Gmbh | Verfahren und Vorrichtung zum Einbetten eines Gegenstandes, insbesondere eines Probematerials, in eine Einbettmasse |
| JP3847559B2 (ja) * | 1998-02-27 | 2006-11-22 | ベンタナ・メデイカル・システムズ・インコーポレーテツド | 独立スライド加熱器を有する自動化分子病理学装置 |
| US20070166834A1 (en) * | 1998-10-05 | 2007-07-19 | Biopath Automation, L.L.C. | Apparatus and method for harvesting and handling tissue samples for biopsy analysis |
| US6780380B2 (en) | 2001-01-16 | 2004-08-24 | Triangle Biomedical Sciences, Inc. | Tissue processor |
| US6458598B1 (en) * | 2001-08-13 | 2002-10-01 | Dako A/S | Process for preparing and presenting a tissue sample for histological study |
| EP1552266B1 (en) * | 2002-09-26 | 2015-10-28 | BioPath Automation, L.L.C. | Apparatus and methods for automated handling and embedding of tissue samples |
| EP2002894B1 (en) * | 2002-09-26 | 2011-12-28 | BioPath Automation, L.L.C. | Staging tool for tissue samples and method of staging a tissue sample cassette |
| US7179424B2 (en) | 2002-09-26 | 2007-02-20 | Biopath Automation, L.L.C. | Cassette for handling and holding tissue samples during processing, embedding and microtome procedures, and methods therefor |
| US7648678B2 (en) * | 2002-12-20 | 2010-01-19 | Dako Denmark A/S | Method and system for pretreatment of tissue slides |
| US7975586B2 (en) * | 2006-02-06 | 2011-07-12 | Leica Biosystems Richmond, Inc. | Microtome and method of reversibly altering a microtome |
| EP2091440B1 (en) * | 2006-12-12 | 2020-04-22 | BioPath Automation, L.L.C. | Biopsy support with sectionable resilient cellular material |
| DE102008025787B3 (de) * | 2008-05-29 | 2010-02-11 | Hirt Zerspanungstechnik Gmbh | Vorrichtung zum Entfernen von überschüssigem Einbettmedium |
| WO2010078240A1 (en) * | 2008-12-30 | 2010-07-08 | Biopath Automation, L.L.C. | Systems and methods for processing tissue samples for histopathology |
| US8329120B2 (en) | 2009-01-22 | 2012-12-11 | Biopath Automation, L.L.C. | Microtome sectionable biopsy support for orienting tissue samples |
| CN103492851B (zh) * | 2011-04-22 | 2016-09-07 | Fei公司 | 样品的自动化制备 |
| US8624199B2 (en) | 2011-10-28 | 2014-01-07 | Fei Company | Sample block holder |
| US8664595B2 (en) | 2012-06-28 | 2014-03-04 | Fei Company | Cluster analysis of unknowns in SEM-EDS dataset |
| US9188555B2 (en) | 2012-07-30 | 2015-11-17 | Fei Company | Automated EDS standards calibration |
| US8937282B2 (en) | 2012-10-26 | 2015-01-20 | Fei Company | Mineral identification using mineral definitions including variability |
| US9778215B2 (en) | 2012-10-26 | 2017-10-03 | Fei Company | Automated mineral classification |
| US9091635B2 (en) | 2012-10-26 | 2015-07-28 | Fei Company | Mineral identification using mineral definitions having compositional ranges |
| US9048067B2 (en) | 2012-10-26 | 2015-06-02 | Fei Company | Mineral identification using sequential decomposition into elements from mineral definitions |
| US9194829B2 (en) | 2012-12-28 | 2015-11-24 | Fei Company | Process for performing automated mineralogy |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2739649A1 (de) * | 1977-05-16 | 1978-11-30 | Fisher Scientific Co | Verfahren und vorrichtung zum behandeln von histologischen gewebeproben |
| EP0139424A2 (en) * | 1983-09-16 | 1985-05-02 | Pelam, Inc. | Method and apparatus for preparing and embedding tissue samples for histological examination |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4155978A (en) * | 1977-04-27 | 1979-05-22 | Nihon Denshi Kabushiki Kaisha | Automatic chemical analyzer |
| US4234540A (en) * | 1979-08-24 | 1980-11-18 | Coulter Electronics, Inc. | Apparatus for monitoring chemical reactions and employing moving photometer means |
| JPS5444592A (en) * | 1977-09-14 | 1979-04-09 | Hitachi Ltd | Automatic analytical apparatus |
| US4668476A (en) * | 1984-03-23 | 1987-05-26 | Applied Biosystems, Inc. | Automated polypeptide synthesis apparatus |
-
1985
- 1985-09-20 JP JP60206578A patent/JPH0640054B2/ja not_active Expired - Lifetime
-
1986
- 1986-09-19 GB GB8711501A patent/GB2189599B/en not_active Expired - Lifetime
- 1986-09-19 WO PCT/JP1986/000488 patent/WO1987001803A1/ja active Application Filing
- 1986-09-19 US US07/057,524 patent/US4834943A/en not_active Expired - Fee Related
- 1986-09-19 DE DE19863690488 patent/DE3690488T/de active Pending
- 1986-09-19 DE DE3690488A patent/DE3690488C2/de not_active Expired - Fee Related
-
1987
- 1987-05-19 SE SE8702056A patent/SE460229B/sv not_active IP Right Cessation
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2739649A1 (de) * | 1977-05-16 | 1978-11-30 | Fisher Scientific Co | Verfahren und vorrichtung zum behandeln von histologischen gewebeproben |
| EP0139424A2 (en) * | 1983-09-16 | 1985-05-02 | Pelam, Inc. | Method and apparatus for preparing and embedding tissue samples for histological examination |
Also Published As
| Publication number | Publication date |
|---|---|
| WO1987001803A1 (en) | 1987-03-26 |
| SE8702056L (sv) | 1987-05-19 |
| JPH0640054B2 (ja) | 1994-05-25 |
| SE460229B (sv) | 1989-09-18 |
| US4834943A (en) | 1989-05-30 |
| JPS6267424A (ja) | 1987-03-27 |
| GB2189599B (en) | 1990-04-04 |
| DE3690488T (OSRAM) | 1988-01-28 |
| GB8711501D0 (en) | 1987-06-17 |
| SE8702056D0 (sv) | 1987-05-19 |
| GB2189599A (en) | 1987-10-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| OP8 | Request for examination as to paragraph 44 patent law | ||
| D2 | Grant after examination | ||
| 8364 | No opposition during term of opposition | ||
| 8328 | Change in the person/name/address of the agent |
Free format text: PATENTANWAELTE REICHEL UND REICHEL, 60322 FRANKFURT |
|
| 8339 | Ceased/non-payment of the annual fee |