DE3686365T2 - Herstellungsverfahren fuer humanes atriales natriuretisches polypeptid. - Google Patents

Herstellungsverfahren fuer humanes atriales natriuretisches polypeptid.

Info

Publication number
DE3686365T2
DE3686365T2 DE8686304723T DE3686365T DE3686365T2 DE 3686365 T2 DE3686365 T2 DE 3686365T2 DE 8686304723 T DE8686304723 T DE 8686304723T DE 3686365 T DE3686365 T DE 3686365T DE 3686365 T2 DE3686365 T2 DE 3686365T2
Authority
DE
Germany
Prior art keywords
hanp
fused
protective peptide
peptide
human atrial
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8686304723T
Other languages
English (en)
Other versions
DE3686365D1 (de
DE3686365T3 (de
Inventor
Ikuo Ueda
Mineo Niwa
Yoshimasa Saito
Hisashi Yamada
Yoshinori Ishii
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fujisawa Pharmaceutical Co Ltd
Original Assignee
Fujisawa Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26289399&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE3686365(T2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GB858515686A external-priority patent/GB8515686D0/en
Priority claimed from GB868600754A external-priority patent/GB8600754D0/en
Application filed by Fujisawa Pharmaceutical Co Ltd filed Critical Fujisawa Pharmaceutical Co Ltd
Publication of DE3686365D1 publication Critical patent/DE3686365D1/de
Publication of DE3686365T2 publication Critical patent/DE3686365T2/de
Application granted granted Critical
Publication of DE3686365T3 publication Critical patent/DE3686365T3/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/58—Atrial natriuretic factor complex; Atriopeptin; Atrial natriuretic peptide [ANP]; Cardionatrin; Cardiodilatin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/32—Fusion polypeptide fusions with soluble part of a cell surface receptor, "decoy receptors"
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/50—Fusion polypeptide containing protease site
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/74—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
    • C07K2319/75—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones
DE3686365T 1985-06-20 1986-06-19 Herstellungsverfahren für humanes atriales natriuretisches Polypeptid. Expired - Fee Related DE3686365T3 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB858515686A GB8515686D0 (en) 1985-06-20 1985-06-20 Production of-human atrial natriuretic polypeptide
GB868600754A GB8600754D0 (en) 1986-01-14 1986-01-14 Human atrial natriuretic polypeptide

Publications (3)

Publication Number Publication Date
DE3686365D1 DE3686365D1 (de) 1992-09-17
DE3686365T2 true DE3686365T2 (de) 1993-01-14
DE3686365T3 DE3686365T3 (de) 2000-07-27

Family

ID=26289399

Family Applications (1)

Application Number Title Priority Date Filing Date
DE3686365T Expired - Fee Related DE3686365T3 (de) 1985-06-20 1986-06-19 Herstellungsverfahren für humanes atriales natriuretisches Polypeptid.

Country Status (5)

Country Link
US (2) US6403336B1 (de)
EP (2) EP0440311A1 (de)
JP (1) JPH0633316B2 (de)
AT (1) ATE79409T1 (de)
DE (1) DE3686365T3 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3686365T3 (de) 1985-06-20 2000-07-27 Fujisawa Pharmaceutical Co Herstellungsverfahren für humanes atriales natriuretisches Polypeptid.
US5340725A (en) * 1986-10-09 1994-08-23 Fujisawa Pharmaceutical Co., Ltd. Expression vector for insulin-like growth factor I and method of production
EP0264074B1 (de) * 1986-10-09 1992-12-30 Fujisawa Pharmaceutical Co., Ltd. Expressionsvektor für menschlichen insulinähnlichen Wachstumsfaktor-I
DK175535B1 (da) * 1987-03-04 2004-11-29 Daiichi Suntory Pharma Co Ltd Fremgangsmåde til fremstilling af et fysiologisk aktivt cysteinholdigt peptid
US7049102B1 (en) 1989-09-22 2006-05-23 Board Of Trustees Of Leland Stanford University Multi-gene expression profile
AUPN283195A0 (en) * 1995-05-05 1995-06-01 Australian Water Technologies Pty Ltd Method for the detection of viable cryptosporidium parvum cells
DE19535445A1 (de) * 1995-09-23 1997-03-27 Boehringer Mannheim Gmbh Verfahren zur Herstellung von natriuretischen Peptiden über Streptavidin-Fusionsproteine
EP1281759B1 (de) * 2000-05-10 2009-07-08 Asubio Pharma Co., Ltd. Verfahren zur hemmung der bildung von nebenprodukten bei der herstellung von genetisch modifizierten polypeptiden
US7357124B2 (en) * 2002-05-10 2008-04-15 Philip Morris Usa Inc. Multiple capillary fuel injector for an internal combustion engine
US7459290B1 (en) 2004-03-30 2008-12-02 Iowa State University Research Foundation, Inc. Methods of using functional 30S subunits
US7337768B2 (en) * 2004-05-07 2008-03-04 Philip Morris Usa Inc. Multiple capillary fuel injector for an internal combustion engine
EP1951277A2 (de) * 2005-10-14 2008-08-06 Biorexis Pharmaceutical Corporation Mit natriuretischem peptid modifizierte transferrin-fusionsproteine

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE871782A (fr) * 1977-11-08 1979-05-07 Genentech Inc Procede permettant l'expression microbienne de polypeptides et moyens appropries
NL7811042A (nl) * 1977-11-08 1979-05-10 Genentech Inc Werkwijze en middel voor het tot uitdrukking brengen van microbieel polypeptide.
IE53166B1 (en) * 1980-08-05 1988-08-03 Searle & Co Synthetic urogastrone gene,corresponding plasmid recombinants,transformed cells,production thereof and urogastrone expression
EP0116784B1 (de) * 1982-02-22 1992-06-10 Queen's University At Kingston Atrial natriuretischer Faktor
GB8314362D0 (en) 1983-05-24 1983-06-29 Celltech Ltd Polypeptide and protein products
US4617149A (en) * 1983-09-21 1986-10-14 Eli Lilly And Company Growth hormone release factor analogs
US4703004A (en) * 1984-01-24 1987-10-27 Immunex Corporation Synthesis of protein with an identification peptide
US4952561A (en) * 1984-02-07 1990-08-28 Merck & Co., Inc. Cardiac atrial peptides
DK108685A (da) * 1984-03-19 1985-09-20 Fujisawa Pharmaceutical Co Vaekstfaktor i
US4745179A (en) * 1984-04-02 1988-05-17 Fujisawa Pharmaceutical Co., Ltd. 59 Valine insulin-like growth factor I and process for production thereof
US4851349A (en) * 1984-04-12 1989-07-25 Mitsubishi Chemical Industries Limited Expression vectors encoding cardionatrin and cardiodilatin
EP0180615B1 (de) * 1984-04-19 1995-04-05 Scios Nova Inc. Atrielle natriumuretische/gefässerweiterende polypeptide
AU600652B2 (en) * 1984-06-08 1990-08-23 Hisayuki Matsuo Human atrial natriuretic peptide and gene encoding same
CA1340625C (en) * 1984-06-29 1999-07-06 Peter L. Davies Cloned cardionatrin cdna
EP0221923A4 (de) * 1985-03-29 1990-03-22 Bioteknika International Sekretionsvektor.
WO1986006742A1 (en) * 1985-05-07 1986-11-20 California Biotechnology Inc. Fused proteine for enzyme immunoassay system
EP0207044A1 (de) * 1985-06-20 1986-12-30 Monsanto Company Freisetzung von Peptiden aus Polypeptiden
DE3686365T3 (de) 1985-06-20 2000-07-27 Fujisawa Pharmaceutical Co Herstellungsverfahren für humanes atriales natriuretisches Polypeptid.
JPS62135500A (ja) * 1985-06-20 1987-06-18 モンサント　コンパニ− ポリペプチドからのペプチドの放出
GB8518753D0 (en) * 1985-07-24 1985-08-29 Glaxo Group Ltd Microbiological products
DK175535B1 (da) * 1987-03-04 2004-11-29 Daiichi Suntory Pharma Co Ltd Fremgangsmåde til fremstilling af et fysiologisk aktivt cysteinholdigt peptid

Also Published As

Publication number Publication date
US20030170811A1 (en) 2003-09-11
JPH0633316B2 (ja) 1994-05-02
EP0440311A1 (de) 1991-08-07
ATE79409T1 (de) 1992-08-15
US6403336B1 (en) 2002-06-11
JPH067187A (ja) 1994-01-18
EP0206769B2 (de) 1999-11-10
DE3686365D1 (de) 1992-09-17
EP0206769A3 (en) 1988-12-28
EP0206769A2 (de) 1986-12-30
DE3686365T3 (de) 2000-07-27
EP0206769B1 (de) 1992-08-12

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Legal Events

Date Code Title Description
8363 Opposition against the patent
8366 Restricted maintained after opposition proceedings
8339 Ceased/non-payment of the annual fee