DE3675348D1 - Lichtinduziertes toeten von karzinomzellen. - Google Patents

Lichtinduziertes toeten von karzinomzellen.

Info

Publication number
DE3675348D1
DE3675348D1 DE8686302602T DE3675348T DE3675348D1 DE 3675348 D1 DE3675348 D1 DE 3675348D1 DE 8686302602 T DE8686302602 T DE 8686302602T DE 3675348 T DE3675348 T DE 3675348T DE 3675348 D1 DE3675348 D1 DE 3675348D1
Authority
DE
Germany
Prior art keywords
light
carcinoma cells
induced killing
chromophore
mitochondria
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE8686302602T
Other languages
English (en)
Inventor
Allan Oseroff
John A Parrish
James Foley
Louis Cincotta
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ROWLAND SCIENCE INST
General Hospital Corp
Original Assignee
ROWLAND SCIENCE INST
General Hospital Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ROWLAND SCIENCE INST, General Hospital Corp filed Critical ROWLAND SCIENCE INST
Application granted granted Critical
Publication of DE3675348D1 publication Critical patent/DE3675348D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N5/0613—Apparatus adapted for a specific treatment
    • A61N5/062—Photodynamic therapy, i.e. excitation of an agent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N5/0601—Apparatus for use inside the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Pathology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Radiation-Therapy Devices (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Quinoline Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pyrane Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DE8686302602T 1985-04-08 1986-04-08 Lichtinduziertes toeten von karzinomzellen. Expired - Lifetime DE3675348D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/720,711 US4651739A (en) 1985-04-08 1985-04-08 Light-induced killing of carcinoma cells

Publications (1)

Publication Number Publication Date
DE3675348D1 true DE3675348D1 (de) 1990-12-06

Family

ID=24895006

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8686302602T Expired - Lifetime DE3675348D1 (de) 1985-04-08 1986-04-08 Lichtinduziertes toeten von karzinomzellen.

Country Status (6)

Country Link
US (1) US4651739A (de)
EP (1) EP0226264B1 (de)
JP (1) JP2505413B2 (de)
AT (1) ATE57948T1 (de)
CA (1) CA1338671C (de)
DE (1) DE3675348D1 (de)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS63111886A (ja) * 1986-10-29 1988-05-17 呉羽化学工業株式会社 光ダイオ−ドを用いた癌治療装置
US5304113A (en) * 1986-11-21 1994-04-19 The Mcw Research Foundation, Inc. Method of eradicating infectious biological contaminants
US4962197A (en) * 1988-02-12 1990-10-09 Rowland Institute For Science Photo-inactivation of cancer cells
US4906750A (en) * 1988-06-08 1990-03-06 Eastman Kodak Company Sulfoalkyl benzoxazoleinylidene butenylidene thiobarbituric acid derivatives
US4937344A (en) * 1988-06-08 1990-06-26 Eastman Kodak Company Novel sulfur-containing merocyanine dyes
US4885366A (en) * 1988-06-08 1989-12-05 Eastman Kodak Company Novel selenium-containing merocyanine dyes
US5152760A (en) * 1989-03-17 1992-10-06 The General Hospital Corporation Non-invasive sclerostomy
US5658892A (en) * 1993-01-15 1997-08-19 The General Hospital Corporation Compound delivery using high-pressure impulse transients
US5405369A (en) * 1994-01-25 1995-04-11 Medical College Of Ohio Photochemical ablation of gastro-intestinal tissue for augmentation of an organ
US5556612A (en) * 1994-03-15 1996-09-17 The General Hospital Corporation Methods for phototherapeutic treatment of proliferative skin diseases
US5885557A (en) * 1996-02-08 1999-03-23 Estee Lauder Inc. Compositions useful in the phototherapeutic treatment of proliferative skin disorders
US6416531B2 (en) * 1998-06-24 2002-07-09 Light Sciences Corporation Application of light at plural treatment sites within a tumor to increase the efficacy of light therapy
US7498156B2 (en) * 1998-07-21 2009-03-03 Caridianbct Biotechnologies, Llc Use of visible light at wavelengths of 500 to 550 nm to reduce the number of pathogens in blood and blood components
US7049110B2 (en) * 1998-07-21 2006-05-23 Gambro, Inc. Inactivation of West Nile virus and malaria using photosensitizers
US6258577B1 (en) 1998-07-21 2001-07-10 Gambro, Inc. Method and apparatus for inactivation of biological contaminants using endogenous alloxazine or isoalloxazine photosensitizers
KR20010075107A (ko) * 1998-09-17 2001-08-09 다께다 가즈히꼬 광화학 요법 치료제
US6183773B1 (en) 1999-01-04 2001-02-06 The General Hospital Corporation Targeting of sebaceous follicles as a treatment of sebaceous gland disorders
US6663658B1 (en) 1999-04-27 2003-12-16 The General Hospital Corporation Phototherapy method for treatment of acne
US7094378B1 (en) 2000-06-15 2006-08-22 Gambro, Inc. Method and apparatus for inactivation of biological contaminants using photosensitizers
US7220747B2 (en) 1999-07-20 2007-05-22 Gambro, Inc. Method for preventing damage to or rejuvenating a cellular blood component using mitochondrial enhancer
US6268120B1 (en) 1999-10-19 2001-07-31 Gambro, Inc. Isoalloxazine derivatives to neutralize biological contaminants
GB0002719D0 (en) * 2000-02-08 2000-03-29 Tissuemed Ltd Thermal ablation of tissue
US7985588B2 (en) * 2000-06-02 2011-07-26 Caridianbct Biotechnologies, Llc Induction of and maintenance of nucleic acid damage in pathogens using riboflavin and light
US7648699B2 (en) * 2000-06-02 2010-01-19 Caridianbct Biotechnologies, Llc Preventing transfusion related complications in a recipient of a blood transfusion
TW590780B (en) * 2000-06-02 2004-06-11 Gambro Inc Additive solutions containing riboflavin
US6843961B2 (en) * 2000-06-15 2005-01-18 Gambro, Inc. Reduction of contaminants in blood and blood products using photosensitizers and peak wavelengths of light
US9044523B2 (en) 2000-06-15 2015-06-02 Terumo Bct, Inc. Reduction of contaminants in blood and blood products using photosensitizers and peak wavelengths of light
EP2269645A3 (de) 2000-08-16 2011-01-12 The General Hospital Corporation doing business as Massachusetts General Hospital Topische photodynamische Therapie mit Aminolävulinsäure für Akne vulgaris
US20020107281A1 (en) * 2000-09-22 2002-08-08 Photogen, Inc. Phototherapeutic and chemotherapeutic immunotherapy against tumors
EP1276734A1 (de) * 2001-04-02 2003-01-22 Theratechnologies Inc. Halogenierte rhodamine derivate und deren verwendungen
DE602004025217D1 (de) 2003-04-04 2010-03-11 Tissuemed Ltd
US7220778B2 (en) * 2003-04-15 2007-05-22 The General Hospital Corporation Methods and devices for epithelial protection during photodynamic therapy
RU2396985C2 (ru) 2004-08-03 2010-08-20 Тиссьюмед Лимитед Материалы, обладающие адгезией к тканям
US8133336B2 (en) 2006-02-03 2012-03-13 Tissuemed Limited Tissue-adhesive materials
ES2454974T3 (es) * 2007-06-27 2014-04-14 The General Hospital Corporation Aparato para la inhibición óptica de la terapia fotodinámica
GB201201641D0 (en) * 2012-01-31 2012-03-14 Univ Central Lancashire Process for dye production
US20150182518A1 (en) 2012-10-26 2015-07-02 Canon Kabushiki Kaisha Cancer cell inhibitory drug and cancer stem-cell detection probe

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE73573C (de) * Badische Anilin- und Sodafabrik in Ludwigshafen a. Rh Verfahren zur Ueberführung von dialkylirten Rhodaminen in höher alkylirte Farbstoffe
US2251286A (en) * 1937-12-30 1941-08-05 Eastman Kodak Co Process of preparing oxatricarbocyanine dyes
US4181128A (en) * 1975-11-28 1980-01-01 Massachusetts Institute Of Technology Virus inactivation applicator and the like
US4336809A (en) * 1980-03-17 1982-06-29 Burleigh Instruments, Inc. Human and animal tissue photoradiation system and method
US4614190A (en) * 1981-09-08 1986-09-30 Alexei Stanco Photoradiation method and arrangement
JPS5940869A (ja) * 1982-08-31 1984-03-06 工業技術院長 レ−ザ光パルスを用いた癌の治療装置
US4512762A (en) * 1982-11-23 1985-04-23 The Beth Israel Hospital Association Method of treatment of atherosclerosis and a balloon catheter for same

Also Published As

Publication number Publication date
JP2505413B2 (ja) 1996-06-12
CA1338671C (en) 1996-10-22
EP0226264A1 (de) 1987-06-24
JPS61288872A (ja) 1986-12-19
ATE57948T1 (de) 1990-11-15
US4651739A (en) 1987-03-24
EP0226264B1 (de) 1990-10-31

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Legal Events

Date Code Title Description
8328 Change in the person/name/address of the agent

Free format text: EISENFUEHR, G., DIPL.-ING. SPEISER, D., DIPL.-ING., 2800 BREMEN STRASSE, J., DIPL.-ING., 8000 MUENCHEN RABUS, W., DR.-ING. BRUEGGE, J., DIPL.-ING., 2800 BREMEN MAIWALD, W., DIPL.-CHEM.DR., 8000 MUENCHEN KLINGHARDT, J., DIPL.-ING., PAT.-ANWAELTE, 2800 BREMEN

8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee