DE3667490D1 - Herstellung von peptiden mit c-terminalem prolinamid. - Google Patents

Herstellung von peptiden mit c-terminalem prolinamid.

Info

Publication number
DE3667490D1
DE3667490D1 DE8686302598T DE3667490T DE3667490D1 DE 3667490 D1 DE3667490 D1 DE 3667490D1 DE 8686302598 T DE8686302598 T DE 8686302598T DE 3667490 T DE3667490 T DE 3667490T DE 3667490 D1 DE3667490 D1 DE 3667490D1
Authority
DE
Germany
Prior art keywords
prolyl
terminal
peptides
production
peptide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8686302598T
Other languages
English (en)
Inventor
Hidetsune Sankyo Bio-S Tamaoki
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sankyo Co Ltd
Original Assignee
Sankyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankyo Co Ltd filed Critical Sankyo Co Ltd
Application granted granted Critical
Publication of DE3667490D1 publication Critical patent/DE3667490D1/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/003—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by transforming the C-terminal amino acid to amides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/585—Calcitonins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Endocrinology (AREA)
  • Analytical Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE8686302598T 1985-04-08 1986-04-08 Herstellung von peptiden mit c-terminalem prolinamid. Expired - Fee Related DE3667490D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP7270585 1985-04-08

Publications (1)

Publication Number Publication Date
DE3667490D1 true DE3667490D1 (de) 1990-01-18

Family

ID=13497032

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8686302598T Expired - Fee Related DE3667490D1 (de) 1985-04-08 1986-04-08 Herstellung von peptiden mit c-terminalem prolinamid.

Country Status (7)

Country Link
US (1) US4709014A (de)
EP (1) EP0197794B1 (de)
JP (1) JPS6229997A (de)
AT (1) ATE48646T1 (de)
CA (1) CA1251153A (de)
DE (1) DE3667490D1 (de)
ES (1) ES8800265A1 (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5332664A (en) * 1981-07-15 1994-07-26 Celltech Limited Human calcitonin precursor polyprotein structural gene
US6319685B1 (en) * 1984-09-27 2001-11-20 Unigene Laboratories, Inc. Alpha-amidating enzyme compositions and processes for their production and use
US5789234A (en) * 1987-08-14 1998-08-04 Unigene Laboratories, Inc. Expression systems for amidating enzyme
US5153308A (en) * 1988-06-16 1992-10-06 Teijin Limited S-sulfonated calcitonin derivatives
JP2535398B2 (ja) * 1989-01-17 1996-09-18 サントリー株式会社 アミド化ペプチドの製造方法
DK220890D0 (da) * 1990-09-14 1990-09-14 Ole Buchardt Fremgangsmaade til fremstilling af c-terminalt amiderede peptider
US5580751A (en) * 1990-09-14 1996-12-03 Carlsberg A/S Process for the preparation of C-terminally amidated peptides
DK67691D0 (da) * 1991-03-01 1991-04-15 Carlbiotech Ltd As Enzymatisk fremgangsmaade til c-terminal modificering af peptider og mellemprodukter til brug ved fremgangsmaaden
ATE173022T1 (de) * 1991-08-08 1998-11-15 Amylin Pharmaceuticals Inc Produktion von peptid-amiden
JP3187201B2 (ja) * 1992-05-14 2001-07-11 三共株式会社 Ｃ末端にプロリンアミドを有するペプチドの製法
US5656456A (en) * 1992-07-13 1997-08-12 Bionebraska, Inc. Chemical method for selective modification of the N- and/or C-terminal amino acid α-carbon reactive group of a recombinant polypeptide or a portion thereof
EP0651761B1 (de) * 1992-07-13 2002-10-09 Bionebraska, Inc. Verfahren zur modifizierung rekombinanter polypeptide
AU4415796A (en) * 1994-12-07 1996-06-26 Bionebraska, Inc. Production of c-terminal amidated peptides from recombinant protein constructs
WO1997045117A1 (en) * 1996-05-29 1997-12-04 Prototek, Inc. Prodrugs of thalidomide and methods for using same as modulators of t-cell function
WO2000010506A2 (en) * 1998-08-20 2000-03-02 University Of Vermont And State Agriculture College Angiogenesis inhibitors and uses thereof
US6461834B1 (en) 1998-11-06 2002-10-08 Bionebraska, Inc. Clostripain catalyzed amidation of peptides
US20130125449A1 (en) * 2011-11-22 2013-05-23 Anthony E. Winston Control of Dust Mites
EP3256144B1 (de) 2015-02-13 2021-03-24 The Board of Trustees of the University of Illionis Peptidhemmung von ccr3-vermittelten krankheiten oder zuständen
JP2022543056A (ja) 2019-07-29 2022-10-07 ザ ボード オブ トラスティーズ オブ ザ ユニヴァーシティ オブ イリノイ 創傷治癒を促進するための組成物および方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3342139A1 (de) * 1983-11-22 1985-05-30 Ciba-Geigy Ag, Basel Desulfatohirudine, verfahren zu ihrer herstellung und pharmazeutische mittel

Also Published As

Publication number Publication date
EP0197794A3 (en) 1988-08-10
CA1251153A (en) 1989-03-14
ES553792A0 (es) 1987-11-01
EP0197794A2 (de) 1986-10-15
ATE48646T1 (de) 1989-12-15
EP0197794B1 (de) 1989-12-13
ES8800265A1 (es) 1987-11-01
US4709014A (en) 1987-11-24
JPS6229997A (ja) 1987-02-07
JPH0570433B2 (de) 1993-10-05

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee