DE3582032D1 - Verfahren zur herstellung von auf einem traeger immobilisierten hochaktiven biologischen verbindungen. - Google Patents

Verfahren zur herstellung von auf einem traeger immobilisierten hochaktiven biologischen verbindungen.

Info

Publication number
DE3582032D1
DE3582032D1 DE8585308832T DE3582032T DE3582032D1 DE 3582032 D1 DE3582032 D1 DE 3582032D1 DE 8585308832 T DE8585308832 T DE 8585308832T DE 3582032 T DE3582032 T DE 3582032T DE 3582032 D1 DE3582032 D1 DE 3582032D1
Authority
DE
Germany
Prior art keywords
carrier
compounds
immobilization
concentration
functional groups
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8585308832T
Other languages
English (en)
Inventor
Peter Hermann
Kornelia Smalla
Jaroslava Turkova
Jiri Coupek
Ingo Wullhardt
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
TESSEK SDRUZENI
Original Assignee
TESSEK SDRUZENI
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by TESSEK SDRUZENI filed Critical TESSEK SDRUZENI
Application granted granted Critical
Publication of DE3582032D1 publication Critical patent/DE3582032D1/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424Serine endopeptidases (3.4.21)
    • C12N9/6427Chymotrypsins (3.4.21.1; 3.4.21.2); Trypsin (3.4.21.4)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/08Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer
    • C12N11/082Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/08Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer
    • C12N11/082Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • C12N11/087Acrylic polymers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/14Enzymes or microbial cells immobilised on or in an inorganic carrier
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/81Carrier - bound or immobilized peptides or proteins and the preparation thereof, e.g. biological cell or cell fragment as carrier
    • Y10S530/811Peptides or proteins is immobilized on, or in, an inorganic carrier
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/81Carrier - bound or immobilized peptides or proteins and the preparation thereof, e.g. biological cell or cell fragment as carrier
    • Y10S530/812Peptides or proteins is immobilized on, or in, an organic carrier

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • General Factory Administration (AREA)
  • Fats And Perfumes (AREA)
DE8585308832T 1984-12-11 1985-12-04 Verfahren zur herstellung von auf einem traeger immobilisierten hochaktiven biologischen verbindungen. Expired - Fee Related DE3582032D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CS849621A CS253971B1 (en) 1984-12-11 1984-12-11 Production method of high active biological effective compounds immobilized on carrier

Publications (1)

Publication Number Publication Date
DE3582032D1 true DE3582032D1 (de) 1991-04-11

Family

ID=5445756

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8585308832T Expired - Fee Related DE3582032D1 (de) 1984-12-11 1985-12-04 Verfahren zur herstellung von auf einem traeger immobilisierten hochaktiven biologischen verbindungen.

Country Status (8)

Country Link
US (1) US4775714A (de)
EP (1) EP0186347B1 (de)
JP (1) JPS61181376A (de)
AT (1) ATE61404T1 (de)
AU (1) AU597568B2 (de)
CS (1) CS253971B1 (de)
DE (1) DE3582032D1 (de)
DK (1) DK544085A (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU4529289A (en) * 1988-10-17 1990-05-14 Sepracor, Inc. Process for the covalent surface modification of hydrophobic polymers and articles made therefrom
US5166319A (en) * 1989-10-10 1992-11-24 Brunswick Corporation Interfacial condensation of bioactive compounds and the site-specific compounds and conjugates thereof
US5200471A (en) * 1990-11-05 1993-04-06 Minnesota Mining And Manufacturing Company Biomolecules covalently immobilized with a high bound specific biological activity and method of preparing same
DE4238389A1 (de) * 1992-11-13 1994-05-19 Bayer Ag Verfahren zur Durchführung immundiagnostischer Nachweise
WO1994022918A1 (en) * 1993-03-29 1994-10-13 Minnesota Mining And Manufacturing Company Method of coupling ligands within porous supports (p.e. azlactone) and uses thereof
CN115646466A (zh) * 2022-11-11 2023-01-31 南通裕弘分析仪器有限公司 核壳结构的有机无机杂化颗粒的制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CS179184B1 (en) * 1975-07-25 1977-10-31 Stanislav Vozka Method for preparation of precisely spherical particles of silica gel with controlled size and controled size pores.
US4440903A (en) * 1978-06-30 1984-04-03 Ramot University Authority For Applied Research And Industrial Development Ltd. Dihaloisocyanide derivatives of polymers for coupling nucleophiles
CS216992B1 (en) * 1980-07-21 1982-12-31 Miroslav Stol Composite polymere material for the biological and medicinal utilitation and method of preparation thereof
DE3106456A1 (de) * 1981-02-21 1982-10-07 Röhm GmbH, 6100 Darmstadt Verfahren zur herstellung von perlfoermigen, hydrophilen, gegenueber proteinen bindungsaktiven traegerpolymeren
DE3112336A1 (de) * 1981-03-28 1982-10-07 Röhm GmbH, 6100 Darmstadt "verfahren zur spaltung von milchzucker"
US4451568A (en) * 1981-07-13 1984-05-29 Battelle Memorial Institute Composition for binding bioactive substances
DE3243591A1 (de) * 1982-11-25 1984-05-30 Hoechst Ag, 6230 Frankfurt Vinylencarbonat-polymerysate, verfahren zu ihrer herstellung und ihre anwendung

Also Published As

Publication number Publication date
CS253971B1 (en) 1987-12-17
DK544085D0 (da) 1985-11-25
EP0186347B1 (de) 1991-03-06
DK544085A (da) 1986-06-12
EP0186347A2 (de) 1986-07-02
AU5107485A (en) 1986-06-19
EP0186347A3 (en) 1987-08-19
CS962184A1 (en) 1987-05-14
ATE61404T1 (de) 1991-03-15
US4775714A (en) 1988-10-04
JPS61181376A (ja) 1986-08-14
AU597568B2 (en) 1990-06-07

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee