DE3579399D1 - Cephalosporinverbindungen und ihre herstellung. - Google Patents
Cephalosporinverbindungen und ihre herstellung.Info
- Publication number
- DE3579399D1 DE3579399D1 DE8585401741T DE3579399T DE3579399D1 DE 3579399 D1 DE3579399 D1 DE 3579399D1 DE 8585401741 T DE8585401741 T DE 8585401741T DE 3579399 T DE3579399 T DE 3579399T DE 3579399 D1 DE3579399 D1 DE 3579399D1
- Authority
- DE
- Germany
- Prior art keywords
- production
- cephalosporine compounds
- cephalosporine
- compounds
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Cephalosporin Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP59186464A JPS61178991A (ja) | 1984-09-07 | 1984-09-07 | 新規セフアロスポリン化合物 |
JP60157005A JPS6219593A (ja) | 1985-07-18 | 1985-07-18 | 新規セフエム化合物 |
Publications (1)
Publication Number | Publication Date |
---|---|
DE3579399D1 true DE3579399D1 (de) | 1990-10-04 |
Family
ID=26484598
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE8585401741T Expired - Lifetime DE3579399D1 (de) | 1984-09-07 | 1985-09-06 | Cephalosporinverbindungen und ihre herstellung. |
Country Status (7)
Country | Link |
---|---|
US (1) | US4839350A (de) |
EP (1) | EP0175610B1 (de) |
KR (1) | KR890001196B1 (de) |
CA (1) | CA1272714A (de) |
DE (1) | DE3579399D1 (de) |
ES (1) | ES8704955A1 (de) |
IE (1) | IE58487B1 (de) |
Families Citing this family (30)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS62205088A (ja) * | 1986-03-03 | 1987-09-09 | Meiji Seika Kaisha Ltd | 新規セフエム化合物 |
US5073551A (en) * | 1988-03-30 | 1991-12-17 | Sagami Chemical Research Center | Cephalosporin compounds |
JPH0678234B2 (ja) | 1988-04-19 | 1994-10-05 | 明治製菓株式会社 | 経口投与用抗菌組成物 |
JPH0686463B2 (ja) * | 1988-07-01 | 1994-11-02 | 明治製菓株式会社 | 新規セフェム化合物、その製造法及び抗菌剤 |
JPH0635464B2 (ja) * | 1988-09-02 | 1994-05-11 | 明治製菓株式会社 | 新規セフェム化合物、その製造法及び抗菌剤 |
IL94946A0 (en) * | 1989-07-13 | 1991-06-10 | Eisai Co Ltd | 3-substituted vinyl cephalosporin derivatives,their preparation and pharmaceutical compositions containing them |
EP0723965B1 (de) * | 1993-09-29 | 2001-05-30 | Meiji Seika Kaisha Ltd. | Neue cephalosporinderivate |
ES2155839T3 (es) | 1993-11-17 | 2001-06-01 | Biochemie Gmbh | Separacion de isomeros de cefalosporina. |
JPH0840907A (ja) | 1994-08-03 | 1996-02-13 | Meiji Seika Kaisha Ltd | セファロスポリン注射剤 |
AR004014A1 (es) * | 1995-10-13 | 1998-09-30 | Meiji Seika Kaisha | Una composicion antibacteriana de cefditoren pivoxilo para administracion oral y metodo para obtener dicha composicion |
TR199900614T2 (xx) * | 1996-09-20 | 1999-06-21 | Meiji Seika Kaisha, Ltd. | Kristal halinde Cefditoren pivoksil maddesi ve bu maddenin �retimi. |
SK283525B6 (sk) * | 1997-06-24 | 2003-09-11 | Meiji Seika Kaisha, Ltd. | Spôsob selektívnej výroby Z-izoméru kyseliny 7-N-nesubstituovaný alebo substituovaný-amino-3-[2-(4-substituovaný alebo nesubstituovaný-tiazol-5-yl)-vinyl]-3-cefem-4-karboxylovej |
DK1325923T3 (da) * | 2000-09-22 | 2007-04-02 | Zenyaku Kogyo Kk | Cephem-forbindelser og ESBL-detekterende reagenser indeholdende disse |
US20030060451A1 (en) * | 2001-05-29 | 2003-03-27 | Rajneesh Taneja | Enhancement of oral bioavailability of non-emulsified formulations of prodrug esters with lecithin |
JP5051865B2 (ja) | 2001-05-29 | 2012-10-17 | タケダ ファーマシューティカルズ ユー.エス.エー. インコーポレイティド | レシチンでのプロドラッグエステル非乳化調合物の経口バイオアベイラビリティの向上 |
KR20030066204A (ko) * | 2002-02-05 | 2003-08-09 | 씨제이 주식회사 | 세프디토렌 중간체의 제조방법 |
US7459550B2 (en) | 2003-07-04 | 2008-12-02 | Orchid Chemicals & Pharmaceuticals Ltd. | Process for the preparation of Cefditoren |
EP1660505A2 (de) * | 2003-08-14 | 2006-05-31 | Ranbaxy Laboratories Limited | Verfahren zur selektiven herstellung des z-isomers von cefditoren und dessen pharmazeutisch unbedenklichen salzen und estern |
ES2379631T3 (es) * | 2003-10-08 | 2012-04-30 | Meiji Seika Pharma Co., Ltd. | Composición antibacteriana no cristalina que contiene cefditoren pivoxilo |
WO2005100367A1 (en) * | 2004-04-13 | 2005-10-27 | Ranbaxy Laboratories Limited | Intermediates useful in the synthesis of 3-(2-substituted vinyl) cephalosporins |
JP4064948B2 (ja) * | 2004-06-04 | 2008-03-19 | 明治製菓株式会社 | 3−アルケニルセフェム化合物及び製造方法 |
EP1954253A4 (de) | 2005-06-08 | 2011-07-27 | Elan Pharma Int Ltd | Nanoteilchenförmige und kontrolliert freigesetzte zusammensetzungen mit cefditoren |
US20080069879A1 (en) * | 2006-05-02 | 2008-03-20 | Ravishekhar Bhiwgade | Stable solid dosage form containing amorphous cefditoren pivoxil and process for preparation thereof |
CA2935651A1 (en) | 2007-10-09 | 2009-04-16 | Gladius Pharmaceuticals Corporation | Broad spectrum beta-lactamase inhibitors |
EP2566451B1 (de) | 2010-05-04 | 2014-09-10 | Mahmut Bilgic | Pharmazeutische zubereitung enthaltend cefditoren pivoxil |
EP2520578A1 (de) | 2011-05-06 | 2012-11-07 | Lupin Limited | Verfahren zur Reinigung von Cephalosporinen |
WO2013109203A1 (en) | 2012-01-18 | 2013-07-25 | Mahmut Bilgic | Tablet formulations comprising cefditoren pivoxil |
DK2968352T3 (da) | 2013-03-12 | 2019-01-02 | Gladius Pharmaceuticals Corp | Derivatiserede 3-styryl-cephalosporiner |
WO2016114727A1 (en) | 2015-01-16 | 2016-07-21 | Öğün Yusuf Toktamiş | Cefditoren pivoxil compositions with improved stability and production methods thereof |
CN105622636B (zh) * | 2016-02-05 | 2017-08-25 | 河南理工大学 | 一种头孢妥仑匹酯中间体的制备方法 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1399086A (en) * | 1971-05-14 | 1975-06-25 | Glaxo Lab Ltd | Cephalosporin compounds |
US4255423A (en) * | 1977-07-27 | 1981-03-10 | Merck & Co., Inc. | Cephalosporin compounds |
CH645117A5 (fr) * | 1979-05-23 | 1984-09-14 | Rhone Poulenc Ind | Thiovinyl-3 cephalosporines, leur preparation et les compositions pharmaceutiques qui les contiennent. |
US4482551A (en) * | 1980-06-26 | 1984-11-13 | Hoffmann-La Roche Inc. | Cephalosporin derivatives |
FR2494280A1 (fr) * | 1980-11-20 | 1982-05-21 | Rhone Poulenc Ind | Nouveaux derives de la cephalosporine et leur preparation |
US4546101A (en) * | 1982-09-10 | 1985-10-08 | Fujisawa Pharmaceutical Co., Ltd. | New cephem compounds useful for treating infectious diseases in human being and animals and processes for preparation thereof |
-
1985
- 1985-08-22 IE IE207185A patent/IE58487B1/en not_active IP Right Cessation
- 1985-08-27 CA CA000489473A patent/CA1272714A/en not_active Expired - Lifetime
- 1985-09-06 KR KR1019850006526A patent/KR890001196B1/ko not_active IP Right Cessation
- 1985-09-06 EP EP85401741A patent/EP0175610B1/de not_active Expired - Lifetime
- 1985-09-06 ES ES546749A patent/ES8704955A1/es not_active Expired
- 1985-09-06 DE DE8585401741T patent/DE3579399D1/de not_active Expired - Lifetime
-
1987
- 1987-04-07 US US07/036,124 patent/US4839350A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
IE852071L (en) | 1986-03-07 |
ES546749A0 (es) | 1987-04-16 |
KR860002511A (ko) | 1986-04-26 |
IE58487B1 (en) | 1993-09-22 |
US4839350A (en) | 1989-06-13 |
CA1272714A (en) | 1990-08-14 |
EP0175610A2 (de) | 1986-03-26 |
ES8704955A1 (es) | 1987-04-16 |
KR890001196B1 (ko) | 1989-04-27 |
EP0175610B1 (de) | 1990-08-29 |
EP0175610A3 (en) | 1987-06-03 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8328 | Change in the person/name/address of the agent |
Free format text: STREHL, P., DIPL.-ING. DIPL.-WIRTSCH.-ING. SCHUEBEL-HOPF, U., DIPL.-CHEM. DR.RER.NAT. GROENING, H., DIPL.-ING., PAT.-ANWAELTE, 8000 MUENCHEN |
|
8364 | No opposition during term of opposition | ||
8327 | Change in the person/name/address of the patent owner |
Owner name: MEIJI SEIKA KAISHA LTD., TOKIO/TOKYO, JP |