ES546749A0 - Un proceso para la produccion de un compuesto de cefalospo- rina - Google Patents
Un proceso para la produccion de un compuesto de cefalospo- rinaInfo
- Publication number
- ES546749A0 ES546749A0 ES546749A ES546749A ES546749A0 ES 546749 A0 ES546749 A0 ES 546749A0 ES 546749 A ES546749 A ES 546749A ES 546749 A ES546749 A ES 546749A ES 546749 A0 ES546749 A0 ES 546749A0
- Authority
- ES
- Spain
- Prior art keywords
- cephalosporine
- compound
- production
- cephalosporine compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Cephalosporin Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP59186464A JPS61178991A (ja) | 1984-09-07 | 1984-09-07 | 新規セフアロスポリン化合物 |
JP60157005A JPS6219593A (ja) | 1985-07-18 | 1985-07-18 | 新規セフエム化合物 |
Publications (2)
Publication Number | Publication Date |
---|---|
ES546749A0 true ES546749A0 (es) | 1987-04-16 |
ES8704955A1 ES8704955A1 (es) | 1987-04-16 |
Family
ID=26484598
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES546749A Expired ES8704955A1 (es) | 1984-09-07 | 1985-09-06 | Un proceso para la produccion de un compuesto de cefalospo- rina |
Country Status (7)
Country | Link |
---|---|
US (1) | US4839350A (es) |
EP (1) | EP0175610B1 (es) |
KR (1) | KR890001196B1 (es) |
CA (1) | CA1272714A (es) |
DE (1) | DE3579399D1 (es) |
ES (1) | ES8704955A1 (es) |
IE (1) | IE58487B1 (es) |
Families Citing this family (30)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS62205088A (ja) * | 1986-03-03 | 1987-09-09 | Meiji Seika Kaisha Ltd | 新規セフエム化合物 |
US5073551A (en) * | 1988-03-30 | 1991-12-17 | Sagami Chemical Research Center | Cephalosporin compounds |
JPH0678234B2 (ja) | 1988-04-19 | 1994-10-05 | 明治製菓株式会社 | 経口投与用抗菌組成物 |
JPH0686463B2 (ja) * | 1988-07-01 | 1994-11-02 | 明治製菓株式会社 | 新規セフェム化合物、その製造法及び抗菌剤 |
JPH0635464B2 (ja) * | 1988-09-02 | 1994-05-11 | 明治製菓株式会社 | 新規セフェム化合物、その製造法及び抗菌剤 |
IL94946A0 (en) * | 1989-07-13 | 1991-06-10 | Eisai Co Ltd | 3-substituted vinyl cephalosporin derivatives,their preparation and pharmaceutical compositions containing them |
DE69427365T2 (de) * | 1993-09-29 | 2002-02-28 | Meiji Seika Kaisha Ltd., Tokio/Tokyo | Neue cephalosporinderivate |
ATE198892T1 (de) * | 1993-11-17 | 2001-02-15 | Biochemie Gmbh | Trennung von cephalosporinisomeren |
JPH0840907A (ja) * | 1994-08-03 | 1996-02-13 | Meiji Seika Kaisha Ltd | セファロスポリン注射剤 |
AR004014A1 (es) * | 1995-10-13 | 1998-09-30 | Meiji Seika Kaisha | Una composicion antibacteriana de cefditoren pivoxilo para administracion oral y metodo para obtener dicha composicion |
EP0937083B1 (en) * | 1996-09-20 | 2003-04-23 | Meiji Seika Kaisha Ltd. | A crystalline substance of cefditoren pivoxil and the production of the same |
ES2182330T3 (es) * | 1997-06-24 | 2003-03-01 | Meiji Seika Kaisha | Procedimiento para la preparacion selectiva de isomeros z de 3-(2-vinil-sustituido) cefalosporina. |
ES2277941T3 (es) * | 2000-09-22 | 2007-08-01 | Zenyaku Kogyo Kabushiki Kaisha | Compuestos cefem y reactivos para la deteccion de esbl que los contienen. |
CA2449002C (en) | 2001-05-29 | 2011-08-16 | Tap Pharmaceutical Products Inc. | Enhancement of oral bioavailability of non-emulsified formulation of prodrug esters with lecithin |
US20030060451A1 (en) * | 2001-05-29 | 2003-03-27 | Rajneesh Taneja | Enhancement of oral bioavailability of non-emulsified formulations of prodrug esters with lecithin |
KR20030066204A (ko) * | 2002-02-05 | 2003-08-09 | 씨제이 주식회사 | 세프디토렌 중간체의 제조방법 |
WO2005003141A2 (en) * | 2003-07-04 | 2005-01-13 | Orchid Chemicals & Pharmaceuticals Ltd | An improved process for the preparation of cefditoren |
EP1660505A2 (en) * | 2003-08-14 | 2006-05-31 | Ranbaxy Laboratories Limited | Process for selective preparation of z-isomer of cefditoren and pharmaceutically acceptable salts and esters thereof |
PT1671635E (pt) * | 2003-10-08 | 2012-01-17 | Meiji Seika Pharma Co Ltd | Composição de antibiótico amorfo contendo cefditoreno pivoxil |
WO2005100367A1 (en) * | 2004-04-13 | 2005-10-27 | Ranbaxy Laboratories Limited | Intermediates useful in the synthesis of 3-(2-substituted vinyl) cephalosporins |
JP4064948B2 (ja) * | 2004-06-04 | 2008-03-19 | 明治製菓株式会社 | 3−アルケニルセフェム化合物及び製造方法 |
DE112006001606T5 (de) | 2005-06-08 | 2009-07-09 | Elan Pharma International Ltd., Athlone | Nanopartikuläre und eine kontrollierte Freisetzung aufweisende Zusammensetzung, die Cefditoren umfassen |
US20080069879A1 (en) * | 2006-05-02 | 2008-03-20 | Ravishekhar Bhiwgade | Stable solid dosage form containing amorphous cefditoren pivoxil and process for preparation thereof |
CA2935651A1 (en) | 2007-10-09 | 2009-04-16 | Gladius Pharmaceuticals Corporation | Broad spectrum beta-lactamase inhibitors |
WO2011139251A1 (en) | 2010-05-04 | 2011-11-10 | Mahmut Bilgic | Pharmaceutical compositions comprising cefditoren pivoxil |
EP2520578A1 (en) | 2011-05-06 | 2012-11-07 | Lupin Limited | Process for purification of cephalosporins |
WO2013109203A1 (en) | 2012-01-18 | 2013-07-25 | Mahmut Bilgic | Tablet formulations comprising cefditoren pivoxil |
EP2968352B1 (en) | 2013-03-12 | 2018-09-26 | Gladius Pharmaceuticals Corporation | Derivatized 3-styryl-cephalosporins |
EP3244879A1 (en) | 2015-01-16 | 2017-11-22 | Ögün, Yusuf Toktamis | Cefditoren pivoxil compositions with improved stability and production methods thereof |
CN105622636B (zh) * | 2016-02-05 | 2017-08-25 | 河南理工大学 | 一种头孢妥仑匹酯中间体的制备方法 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1399086A (en) * | 1971-05-14 | 1975-06-25 | Glaxo Lab Ltd | Cephalosporin compounds |
US4255423A (en) * | 1977-07-27 | 1981-03-10 | Merck & Co., Inc. | Cephalosporin compounds |
HU184771B (en) * | 1979-05-23 | 1984-10-29 | Rhone Poulenc Ind | Process for producing new 3-thiovinyl-cepheme-carboxylic acid derivatives |
US4482551A (en) * | 1980-06-26 | 1984-11-13 | Hoffmann-La Roche Inc. | Cephalosporin derivatives |
FR2494280A1 (fr) * | 1980-11-20 | 1982-05-21 | Rhone Poulenc Ind | Nouveaux derives de la cephalosporine et leur preparation |
US4546101A (en) * | 1982-09-10 | 1985-10-08 | Fujisawa Pharmaceutical Co., Ltd. | New cephem compounds useful for treating infectious diseases in human being and animals and processes for preparation thereof |
-
1985
- 1985-08-22 IE IE207185A patent/IE58487B1/en not_active IP Right Cessation
- 1985-08-27 CA CA000489473A patent/CA1272714A/en not_active Expired - Lifetime
- 1985-09-06 EP EP85401741A patent/EP0175610B1/en not_active Expired - Lifetime
- 1985-09-06 DE DE8585401741T patent/DE3579399D1/de not_active Expired - Lifetime
- 1985-09-06 KR KR1019850006526A patent/KR890001196B1/ko not_active IP Right Cessation
- 1985-09-06 ES ES546749A patent/ES8704955A1/es not_active Expired
-
1987
- 1987-04-07 US US07/036,124 patent/US4839350A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
IE58487B1 (en) | 1993-09-22 |
US4839350A (en) | 1989-06-13 |
ES8704955A1 (es) | 1987-04-16 |
EP0175610A2 (en) | 1986-03-26 |
EP0175610A3 (en) | 1987-06-03 |
CA1272714A (en) | 1990-08-14 |
IE852071L (en) | 1986-03-07 |
DE3579399D1 (de) | 1990-10-04 |
EP0175610B1 (en) | 1990-08-29 |
KR890001196B1 (ko) | 1989-04-27 |
KR860002511A (ko) | 1986-04-26 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
SPCF | Request for supplementary protection certificate filed |
Free format text: PRODUCT NAME: CEFDITOREN PIVOXIL (SPECTRACEF), REGISTRY NO/DATE: 65942 20040322 Spc suppl protection certif: C200400020 Filing date: 20040830 |
|
SPCG | Supplementary protection certificate granted |
Free format text: PRODUCT NAME: CEFDITOREN PIVOXIL (SPECTRACEF), REGISTRY NO/DATE: 65942 20040322 Spc suppl protection certif: C200400020 Filing date: 20040830 |
|
FD2A | Announcement of lapse in spain |
Effective date: 20151230 |