DE3571974D1 - Substituted dihydroquinolone carboxylic acids, anti-bacterial compositions containing them - Google Patents

Substituted dihydroquinolone carboxylic acids, anti-bacterial compositions containing them

Info

Publication number
DE3571974D1
DE3571974D1 DE8585308651T DE3571974T DE3571974D1 DE 3571974 D1 DE3571974 D1 DE 3571974D1 DE 8585308651 T DE8585308651 T DE 8585308651T DE 3571974 T DE3571974 T DE 3571974T DE 3571974 D1 DE3571974 D1 DE 3571974D1
Authority
DE
Germany
Prior art keywords
dihydroquinolone
substituted
carboxylic acids
compositions containing
bacterial compositions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8585308651T
Other languages
English (en)
Inventor
Paul J Gilligan
Michael J Witty
Paul R Mcguirk
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Inc
Original Assignee
Pfizer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/679,150 external-priority patent/US4623650A/en
Application filed by Pfizer Inc filed Critical Pfizer Inc
Application granted granted Critical
Publication of DE3571974D1 publication Critical patent/DE3571974D1/de
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20Oxygen atoms
    • C07D215/22Oxygen atoms attached in position 2 or 4
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C07D215/56Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02Silicon compounds
    • C07F7/08Compounds having one or more C—Si linkages
    • C07F7/18Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804Compounds having Si-O-C linkages

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE8585308651T 1984-12-06 1985-11-28 Substituted dihydroquinolone carboxylic acids, anti-bacterial compositions containing them Expired DE3571974D1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US67914684A 1984-12-06 1984-12-06
US06/679,150 US4623650A (en) 1984-12-06 1984-12-06 Antibiotic derivatives of 7-phenyl-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids

Publications (1)

Publication Number Publication Date
DE3571974D1 true DE3571974D1 (en) 1989-09-07

Family

ID=27102160

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8585308651T Expired DE3571974D1 (en) 1984-12-06 1985-11-28 Substituted dihydroquinolone carboxylic acids, anti-bacterial compositions containing them

Country Status (13)

Country Link
EP (1) EP0184384B1 (de)
KR (1) KR880000429B1 (de)
AU (1) AU562237B2 (de)
CA (1) CA1262249A (de)
DE (1) DE3571974D1 (de)
DK (1) DK562985A (de)
ES (1) ES8704901A1 (de)
FI (1) FI83643C (de)
GR (1) GR852923B (de)
HU (1) HU195780B (de)
IE (1) IE58270B1 (de)
PH (1) PH23499A (de)
PT (1) PT81614B (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1196429B (it) * 1986-07-01 1988-11-16 Mediolanum Farmaceutici Srl Processo per la preparazione di pirido benzotiazine ad attivita' antibatterica e loro sali con acidi solfonici
US4929613A (en) * 1987-08-26 1990-05-29 Warner-Lambert Company Antibacterial agents
NO172846C (no) * 1987-12-25 1993-09-15 Daiichi Seiyaku Co Fremgangsmaate for fremstilling av 7,8-dihalogen-3-metyl-2,3-dihydro-2m-benzoksazinderivater og propoksybenzenderivater for utoevelse av fremgangsmaaten.
AU2325300A (en) * 1999-02-05 2000-08-25 Toyama Chemical Co. Ltd. Tricyclic quinolonecarboxylic acid derivatives or salts thereof
EP1340759A1 (de) * 2002-02-28 2003-09-03 Sanofi-Synthelabo 1-Alkyl, 1-(Heteroaryl)alkyl und 1-(Aryl)alkyl-7-pyrimidin-4-ylimidazo[1,2-a]pyrimidin-5(1H)-on Derivate
JO3002B1 (ar) 2009-08-28 2016-09-05 Irm Llc مركبات و تركيبات كمثبطات كيناز بروتين
CN118255716A (zh) * 2022-12-26 2024-06-28 深圳阿尔法分子科技有限责任公司 一种新型具有抗菌和抗癌功能的苯基喹诺酮类化合物及其制备
WO2024138292A1 (zh) * 2022-12-26 2024-07-04 深圳阿尔法分子科技有限责任公司 一种新型具有抗菌和抗癌功能的苯基喹诺酮类化合物及其制备

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3472859A (en) * 1966-11-01 1969-10-14 Sterling Drug Inc 1-alkyl-1,4-dihydro-4-oxo-3 quinoline-carboxylic acids and esters
CA1034124A (en) * 1973-05-11 1978-07-04 Ciba-Geigy Ag Process for the manufacture of new quinolines
DD136742B1 (de) * 1978-03-02 1981-05-27 Eberhard Schroetter Verfahren zur herstellung substituierter chinoline
JPS5746986A (en) * 1980-09-02 1982-03-17 Dai Ichi Seiyaku Co Ltd Pyrido(1,2,3-de)(1,4)benzoxazine derivative
JPS57145862A (en) * 1981-03-06 1982-09-09 Kyorin Pharmaceut Co Ltd Quinolinecarboxylic acid derivative

Also Published As

Publication number Publication date
DK562985A (da) 1986-06-07
PH23499A (en) 1989-08-16
FI854829A (fi) 1986-06-07
KR880000429B1 (ko) 1988-03-23
PT81614B (pt) 1988-04-21
FI83643B (fi) 1991-04-30
AU5079285A (en) 1986-06-12
HUT39162A (en) 1986-08-28
DK562985D0 (da) 1985-12-05
HU195780B (en) 1988-07-28
FI83643C (fi) 1991-08-12
IE853077L (en) 1986-06-06
ES8704901A1 (es) 1987-04-16
CA1262249A (en) 1989-10-10
KR860004857A (ko) 1986-07-14
GR852923B (de) 1986-04-07
AU562237B2 (en) 1987-06-04
ES549601A0 (es) 1987-04-16
FI854829A0 (fi) 1985-12-05
PT81614A (en) 1986-01-01
EP0184384A1 (de) 1986-06-11
EP0184384B1 (de) 1989-08-02
IE58270B1 (en) 1993-08-25

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee