DE3485386D1 - Chemisches verfahren zur herstellung von antibiotikum l 17392 (deglucoteicoplanin) und dessen salzen. - Google Patents
Chemisches verfahren zur herstellung von antibiotikum l 17392 (deglucoteicoplanin) und dessen salzen.Info
- Publication number
- DE3485386D1 DE3485386D1 DE8484114558T DE3485386T DE3485386D1 DE 3485386 D1 DE3485386 D1 DE 3485386D1 DE 8484114558 T DE8484114558 T DE 8484114558T DE 3485386 T DE3485386 T DE 3485386T DE 3485386 D1 DE3485386 D1 DE 3485386D1
- Authority
- DE
- Germany
- Prior art keywords
- deglucoteicoplanin
- salt
- chemical method
- producing antibiotic
- antibiotic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 238000004519 manufacturing process Methods 0.000 title 1
- 150000003839 salts Chemical class 0.000 title 1
- DKVBOUDTNWVDEP-NJCHZNEYSA-N teicoplanin aglycone Chemical compound N([C@H](C(N[C@@H](C1=CC(O)=CC(O)=C1C=1C(O)=CC=C2C=1)C(O)=O)=O)[C@H](O)C1=CC=C(C(=C1)Cl)OC=1C=C3C=C(C=1O)OC1=CC=C(C=C1Cl)C[C@H](C(=O)N1)NC([C@H](N)C=4C=C(O5)C(O)=CC=4)=O)C(=O)[C@@H]2NC(=O)[C@@H]3NC(=O)[C@@H]1C1=CC5=CC(O)=C1 DKVBOUDTNWVDEP-NJCHZNEYSA-N 0.000 title 1
- DKVBOUDTNWVDEP-ZCVCDMNQSA-N teicoplanin aglycone Chemical compound N([C@H](C(N[C@@H](C1=CC(O)=CC(O)=C1C=1C(O)=CC=C2C=1)C(O)=O)=O)[C@H](O)C1=CC=C(C(=C1)Cl)OC=1C=C3C=C(C=1O)OC1=CC=C(C=C1Cl)C[C@H](C(=O)N1)NC([C@H](N)C=4C=C(O5)C(O)=CC=4)=O)C(=O)C2NC(=O)[C@@H]3NC(=O)[C@@H]1C1=CC5=CC(O)=C1 DKVBOUDTNWVDEP-ZCVCDMNQSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
- C07K9/006—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure
- C07K9/008—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure directly attached to a hetero atom of the saccharide radical, e.g. actaplanin, avoparcin, ristomycin, vancomycin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S930/00—Peptide or protein sequence
- Y10S930/01—Peptide or protein sequence
- Y10S930/19—Antibiotic
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S930/00—Peptide or protein sequence
- Y10S930/01—Peptide or protein sequence
- Y10S930/27—Cyclic peptide or cyclic protein
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB838333624A GB8333624D0 (en) | 1983-12-16 | 1983-12-16 | Antibiotics l 17054 and l 17392 |
GB848415091A GB8415091D0 (en) | 1984-06-13 | 1984-06-13 | Deglutcoteicoplanin and acids |
Publications (1)
Publication Number | Publication Date |
---|---|
DE3485386D1 true DE3485386D1 (de) | 1992-02-06 |
Family
ID=26287114
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE8484114558T Expired - Fee Related DE3485386D1 (de) | 1983-12-16 | 1984-11-30 | Chemisches verfahren zur herstellung von antibiotikum l 17392 (deglucoteicoplanin) und dessen salzen. |
Country Status (19)
Country | Link |
---|---|
US (1) | US4629781A (de) |
EP (1) | EP0146053B1 (de) |
JP (1) | JPH0653746B2 (de) |
KR (1) | KR920001691B1 (de) |
AR (1) | AR242224A1 (de) |
AU (1) | AU579120B2 (de) |
CA (1) | CA1250093A (de) |
DE (1) | DE3485386D1 (de) |
DK (1) | DK584384A (de) |
ES (1) | ES538618A0 (de) |
FI (1) | FI87079C (de) |
GR (1) | GR81032B (de) |
HU (1) | HU194281B (de) |
IE (1) | IE57697B1 (de) |
IL (1) | IL73805A (de) |
NO (1) | NO170019C (de) |
NZ (1) | NZ210543A (de) |
PH (1) | PH20212A (de) |
PT (1) | PT79683B (de) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1173329B (it) * | 1984-02-21 | 1987-06-24 | Lepetit Spa | Procedimento per la trasformazione quantitativa di teicoplanina a2 fattore 1 in teicoplanina a2 fattore 3 |
GB8415092D0 (en) * | 1984-06-13 | 1984-07-18 | Lepetit Spa | Ester derivatives |
GB8420405D0 (en) * | 1984-08-10 | 1984-09-12 | Lepetit Spa | Preparing antibiotic l 17046 |
GB8522574D0 (en) * | 1985-09-12 | 1985-10-16 | Lepetit Spa | Amides of teicoplanin compounds |
GB8608809D0 (en) * | 1986-04-11 | 1986-05-14 | Lepetit Spa | Antibiotic |
GB8701872D0 (en) * | 1987-01-28 | 1987-03-04 | Lepetit Spa | N15-alkyl & n15,n15-dialkyl derivatives |
GB8704847D0 (en) * | 1987-03-02 | 1987-04-08 | Lepetit Spa | Substituted alkylamides of teicoplanin compounds |
GB8711066D0 (en) * | 1987-05-11 | 1987-06-17 | Lepetit Spa | Teicoplanin derivatives |
GB8715735D0 (en) * | 1987-07-03 | 1987-08-12 | Lepetit Spa | De-mannosyl teicoplanin derivatives |
EP0376042B1 (de) * | 1988-12-27 | 1996-03-13 | GRUPPO LEPETIT S.p.A. | Chemisches Verfahren zur Herstellung des Antibiotikums L 17392 (Deglukoteicoplanin) und dessen Salze |
US5500410A (en) * | 1989-03-29 | 1996-03-19 | Gruppo Lepetit S.P.A. | Substituted alkylamide derivatives of teicoplanin |
US5185320A (en) * | 1989-04-03 | 1993-02-09 | Gruppo Lepetit S.P.A. | O56 -alkyl derivatives of aglycone and pseudo aglycones of teicoplanin |
DE69127645T2 (de) | 1990-03-28 | 1998-02-12 | Lepetit Spa | Verfahren zur Herstellung von Mannosylteicoplaninderivaten und Mannosylteicoplaninaglykon |
HUT63860A (en) * | 1990-12-05 | 1993-10-28 | Lepetit Spa | Process for producing 39-decarboxy-38-(hydroxymethyl) derivatives of teikoplanin antibiotics |
WO1997040067A1 (en) | 1996-04-23 | 1997-10-30 | Biosearch Italia S.P.A. | Improved chemical process for preparing amide derivatives of antibiotic a 40926 |
KR100554481B1 (ko) * | 2004-06-30 | 2006-03-03 | 씨제이 주식회사 | 반코마이신 염산염의 정제방법 |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1496386A (en) * | 1975-03-05 | 1977-12-30 | Lepetit Spa | Antibiotics |
US4322406A (en) * | 1980-12-18 | 1982-03-30 | Eli Lilly And Company | Antibiotic A-4696 factors B1, B2, B3, C1a, C3 and E1 |
FI75190C (fi) * | 1982-03-24 | 1988-05-09 | Lilly Co Eli | Foerfarande foer framstaellning av ett antibiotikum a41030-komplex eller dess faktorer a, b, c, d, e, f och g. |
US4462942A (en) * | 1982-07-30 | 1984-07-31 | Eli Lilly And Company | A47934 Antibiotic and process for production thereof |
GB8307847D0 (en) * | 1983-03-22 | 1983-04-27 | Lepetit Spa | Antibiotics l 17054 and l 17046 |
US4521335A (en) * | 1983-07-13 | 1985-06-04 | Smithkline Beckman Corporation | Aglycone and pseudo-aglycones of the AAD 216 antibiotics |
US4497802A (en) * | 1983-10-21 | 1985-02-05 | Eli Lilly And Company | N-Acyl glycopeptide derivatives |
GB8415092D0 (en) * | 1984-06-13 | 1984-07-18 | Lepetit Spa | Ester derivatives |
GB8415093D0 (en) * | 1984-06-13 | 1984-07-18 | Lepetit Spa | Antibiotic l 17392 |
-
1984
- 1984-11-21 AU AU35734/84A patent/AU579120B2/en not_active Ceased
- 1984-11-23 GR GR81032A patent/GR81032B/el unknown
- 1984-11-30 EP EP84114558A patent/EP0146053B1/de not_active Expired
- 1984-11-30 DE DE8484114558T patent/DE3485386D1/de not_active Expired - Fee Related
- 1984-12-05 PH PH31530A patent/PH20212A/en unknown
- 1984-12-07 DK DK584384A patent/DK584384A/da not_active Application Discontinuation
- 1984-12-11 US US06/680,435 patent/US4629781A/en not_active Expired - Lifetime
- 1984-12-12 IL IL73805A patent/IL73805A/xx unknown
- 1984-12-13 NZ NZ210543A patent/NZ210543A/xx unknown
- 1984-12-13 NO NO845005A patent/NO170019C/no unknown
- 1984-12-14 JP JP59263081A patent/JPH0653746B2/ja not_active Expired - Lifetime
- 1984-12-14 KR KR1019840007973A patent/KR920001691B1/ko not_active IP Right Cessation
- 1984-12-14 CA CA000470136A patent/CA1250093A/en not_active Expired
- 1984-12-14 AR AR84298965A patent/AR242224A1/es active
- 1984-12-14 HU HU844673A patent/HU194281B/hu not_active IP Right Cessation
- 1984-12-14 FI FI844963A patent/FI87079C/fi not_active IP Right Cessation
- 1984-12-14 ES ES538618A patent/ES538618A0/es active Granted
- 1984-12-14 IE IE3218/84A patent/IE57697B1/en not_active IP Right Cessation
- 1984-12-14 PT PT79683A patent/PT79683B/pt not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
AR242224A1 (es) | 1993-03-31 |
DK584384A (da) | 1985-06-17 |
PT79683A (en) | 1985-01-01 |
JPS60243091A (ja) | 1985-12-03 |
IL73805A (en) | 1988-05-31 |
US4629781A (en) | 1986-12-16 |
NO170019B (no) | 1992-05-25 |
NZ210543A (en) | 1988-07-28 |
FI87079C (fi) | 1992-11-25 |
NO170019C (no) | 1992-09-02 |
AU3573484A (en) | 1985-06-20 |
EP0146053B1 (de) | 1991-12-27 |
EP0146053A3 (en) | 1987-05-13 |
EP0146053A2 (de) | 1985-06-26 |
NO845005L (no) | 1985-06-17 |
PT79683B (en) | 1986-12-10 |
HUT36838A (en) | 1985-10-28 |
KR850004496A (ko) | 1985-07-15 |
ES8507569A1 (es) | 1985-09-01 |
IE57697B1 (en) | 1993-03-10 |
GR81032B (en) | 1985-02-27 |
HU194281B (en) | 1988-01-28 |
KR920001691B1 (ko) | 1992-02-22 |
CA1250093A (en) | 1989-02-14 |
IL73805A0 (en) | 1985-03-31 |
ES538618A0 (es) | 1985-09-01 |
FI844963L (fi) | 1985-06-17 |
PH20212A (en) | 1986-10-21 |
JPH0653746B2 (ja) | 1994-07-20 |
IE843218L (en) | 1985-06-16 |
FI844963A0 (fi) | 1984-12-14 |
DK584384D0 (da) | 1984-12-07 |
FI87079B (fi) | 1992-08-14 |
AU579120B2 (en) | 1988-11-17 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |