DE3479800D1 - A method for the preparation of isosorbide-5-nitrate and sodium isosorbide-5-nitrate hydrate as a precursor thereof - Google Patents

A method for the preparation of isosorbide-5-nitrate and sodium isosorbide-5-nitrate hydrate as a precursor thereof

Info

Publication number
DE3479800D1
DE3479800D1 DE8484304816T DE3479800T DE3479800D1 DE 3479800 D1 DE3479800 D1 DE 3479800D1 DE 8484304816 T DE8484304816 T DE 8484304816T DE 3479800 T DE3479800 T DE 3479800T DE 3479800 D1 DE3479800 D1 DE 3479800D1
Authority
DE
Germany
Prior art keywords
isosorbide
nitrate
precursor
sodium
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8484304816T
Other languages
English (en)
Inventor
Toshio Ito
Susumu Ishiguro
Fumitake Shimada
Kenichi Ishibashi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Toshin Chemical Co Ltd
Original Assignee
Toshin Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP58221476A external-priority patent/JPS60115587A/ja
Priority claimed from JP58221477A external-priority patent/JPS60115588A/ja
Application filed by Toshin Chemical Co Ltd filed Critical Toshin Chemical Co Ltd
Application granted granted Critical
Publication of DE3479800D1 publication Critical patent/DE3479800D1/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
DE8484304816T 1983-11-25 1984-07-13 A method for the preparation of isosorbide-5-nitrate and sodium isosorbide-5-nitrate hydrate as a precursor thereof Expired DE3479800D1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP58221476A JPS60115587A (ja) 1983-11-25 1983-11-25 イソソルビド−５−ニトレ−ト・ナトリウム水和物及びその製造方法
JP58221477A JPS60115588A (ja) 1983-11-25 1983-11-25 イソソルビド−５−ニトレ−トの製造方法

Publications (1)

Publication Number Publication Date
DE3479800D1 true DE3479800D1 (en) 1989-10-26

Family

ID=26524329

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8484304816T Expired DE3479800D1 (en) 1983-11-25 1984-07-13 A method for the preparation of isosorbide-5-nitrate and sodium isosorbide-5-nitrate hydrate as a precursor thereof

Country Status (3)

Country Link
US (1) US4584391A (de)
EP (1) EP0143507B1 (de)
DE (1) DE3479800D1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4410997A1 (de) * 1994-03-30 1995-10-26 Isis Pharma Gmbh Pharmazeutische Zubereitungen und Arzneistoffe zur Prävention und Behandlung endothelialer Dysfunktionen
DE102008050597A1 (de) 2008-10-09 2010-04-15 Actavis Deutschland Gmbh & Co. Kg Pharmazeutische Zubereitungen zur Anwendung in einem Verfahren zur therapeutischen Behandlung von Hörsturz
CN103641840B (zh) * 2013-11-28 2016-03-16 青岛黄海制药有限责任公司 一种5-单硝酸异山梨酯的合成与纯化方法
CN104876942B (zh) * 2015-05-08 2017-08-25 天津梅花生物医药科技有限公司 单硝酸异山梨酯半水化合物
US10703707B2 (en) 2018-11-07 2020-07-07 Industrial Technology Research Institute Method for preparing nitrate ester
CN113109494B (zh) * 2021-04-29 2023-03-31 南京威尔生物科技有限公司 一种油酸山梨坦的薄层色谱分析方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1356374A (en) * 1971-04-29 1974-06-12 American Home Prod Mononitrate esters of 1,3 3,6-dianhydro-d-glucitol
US3886186A (en) * 1971-04-29 1975-05-27 American Home Prod Mononitrate esters of 1,4:3,6-dianhydro-d-glucitol
DE3117612A1 (de) * 1981-05-05 1982-11-25 Cassella Ag, 6000 Frankfurt Verfahren zur herstellung von isosorbid-5-nitrat
DE3124410A1 (de) * 1981-06-22 1983-01-05 Heinrich Mack Nachf., 7918 Illertissen Verfahren zur herstellung von isosorbid-2-nitrat

Also Published As

Publication number Publication date
EP0143507A1 (de) 1985-06-05
EP0143507B1 (de) 1989-09-20
US4584391A (en) 1986-04-22

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee