DE3478689D1 - Neocarzinostatin derivatives and a process for manufacturing the same - Google Patents

Neocarzinostatin derivatives and a process for manufacturing the same

Info

Publication number
DE3478689D1
DE3478689D1 DE8484305414T DE3478689T DE3478689D1 DE 3478689 D1 DE3478689 D1 DE 3478689D1 DE 8484305414 T DE8484305414 T DE 8484305414T DE 3478689 T DE3478689 T DE 3478689T DE 3478689 D1 DE3478689 D1 DE 3478689D1
Authority
DE
Germany
Prior art keywords
residue
neocarzinostatin
maleic acid
sma
chem
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8484305414T
Other languages
German (de)
English (en)
Inventor
Hiroshi Maeda
Ryunosuke Kanamaru
Nakao Ishida
Toshihiko Yoshitake
Minoru Ueda
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
KAYAKU ALSO TRADING AS KAYAKU
Kuraray Co Ltd
Yamanouchi Pharmaceutical Co Ltd
Original Assignee
KAYAKU ALSO TRADING AS KAYAKU
Kuraray Co Ltd
Yamanouchi Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by KAYAKU ALSO TRADING AS KAYAKU, Kuraray Co Ltd, Yamanouchi Pharmaceutical Co Ltd filed Critical KAYAKU ALSO TRADING AS KAYAKU
Application granted granted Critical
Publication of DE3478689D1 publication Critical patent/DE3478689D1/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
DE8484305414T 1983-08-08 1984-08-08 Neocarzinostatin derivatives and a process for manufacturing the same Expired DE3478689D1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP58145419A JPS6075499A (ja) 1983-08-08 1983-08-08 ネオカルチノスタチン誘導体及びその製造法

Publications (1)

Publication Number Publication Date
DE3478689D1 true DE3478689D1 (en) 1989-07-20

Family

ID=15384811

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8484305414T Expired DE3478689D1 (en) 1983-08-08 1984-08-08 Neocarzinostatin derivatives and a process for manufacturing the same

Country Status (6)

Country Link
US (1) US4762885A (https=)
EP (1) EP0136792B1 (https=)
JP (1) JPS6075499A (https=)
AT (1) ATE44035T1 (https=)
CA (1) CA1241640A (https=)
DE (1) DE3478689D1 (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2556865B2 (ja) * 1986-09-19 1996-11-27 山之内製薬株式会社 ネオカルチノスタチン誘導体の非注射投与用組成物
US5389366A (en) * 1986-09-19 1995-02-14 Yamanouchi Pharmaceutical Co., Ltd. Neocarzinostatin derivative composition for oral administration
CA1327161C (en) * 1987-09-01 1994-02-22 Mitsugu Kobayashi Lyophilized pharmaceutical composition of neocarzinostatin derivative
EP1627645B1 (en) * 2003-05-26 2017-08-23 Hiroshi Maeda Antitumor agent and process for producing the same
JPWO2006080171A1 (ja) 2005-01-31 2008-06-19 株式会社 エフェクター細胞研究所 免疫増強剤
EP3072910A4 (en) 2013-11-19 2018-02-21 Hiroshi Maeda Derivative of styrene-maleic acid copolymer

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3085994A (en) * 1959-10-30 1963-04-16 Sinclair Research Inc Chain terminated copolymer of styrene and maleic anhydride of low solution viscosity
US3121043A (en) * 1960-05-11 1964-02-11 Scient Associates Inc Sustained release pharmaceutical preparation and methods for making same
US3245933A (en) * 1960-05-19 1966-04-12 Sinclair Research Inc Styrene-maleic anhydride copolymers cross-linked with aliphatic polyhydroxy compounds
JPS6017206B2 (ja) * 1977-03-24 1985-05-01 浩 前田 ネオカルチノスタチン誘導体の製造法
EP0087957B1 (en) * 1982-02-27 1986-11-26 Kuraray Co., Ltd. Neocarzinostatin complexes, a method for producing the same, and an antitumor agent containing said complexes as an active component

Also Published As

Publication number Publication date
ATE44035T1 (de) 1989-06-15
EP0136792A2 (en) 1985-04-10
EP0136792B1 (en) 1989-06-14
US4762885A (en) 1988-08-09
CA1241640A (en) 1988-09-06
EP0136792A3 (en) 1985-12-18
JPH0133120B2 (https=) 1989-07-11
JPS6075499A (ja) 1985-04-27

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee