ATE44035T1 - Derivate des neocarzinostatins und verfahren zu deren herstellung. - Google Patents

Derivate des neocarzinostatins und verfahren zu deren herstellung.

Info

Publication number
ATE44035T1
ATE44035T1 AT84305414T AT84305414T ATE44035T1 AT E44035 T1 ATE44035 T1 AT E44035T1 AT 84305414 T AT84305414 T AT 84305414T AT 84305414 T AT84305414 T AT 84305414T AT E44035 T1 ATE44035 T1 AT E44035T1
Authority
AT
Austria
Prior art keywords
residue
neocarzinostatin
maleic acid
sma
chem
Prior art date
Application number
AT84305414T
Other languages
German (de)
English (en)
Inventor
Hiroshi Maeda
Ryunosuke Kanamaru
Nakao Ishida
Toshihiko Yoshitake
Minoru Ueda
Original Assignee
Kuraray Co
Yamanouchi Pharma Co Ltd
Kayaku Also Trading As Kayaku
Hiroshi Maeda
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kuraray Co, Yamanouchi Pharma Co Ltd, Kayaku Also Trading As Kayaku, Hiroshi Maeda filed Critical Kuraray Co
Application granted granted Critical
Publication of ATE44035T1 publication Critical patent/ATE44035T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
AT84305414T 1983-08-08 1984-08-08 Derivate des neocarzinostatins und verfahren zu deren herstellung. ATE44035T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP58145419A JPS6075499A (ja) 1983-08-08 1983-08-08 ネオカルチノスタチン誘導体及びその製造法
EP84305414A EP0136792B1 (en) 1983-08-08 1984-08-08 Neocarzinostatin derivatives and a process for manufacturing the same

Publications (1)

Publication Number Publication Date
ATE44035T1 true ATE44035T1 (de) 1989-06-15

Family

ID=15384811

Family Applications (1)

Application Number Title Priority Date Filing Date
AT84305414T ATE44035T1 (de) 1983-08-08 1984-08-08 Derivate des neocarzinostatins und verfahren zu deren herstellung.

Country Status (6)

Country Link
US (1) US4762885A (https=)
EP (1) EP0136792B1 (https=)
JP (1) JPS6075499A (https=)
AT (1) ATE44035T1 (https=)
CA (1) CA1241640A (https=)
DE (1) DE3478689D1 (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2556865B2 (ja) * 1986-09-19 1996-11-27 山之内製薬株式会社 ネオカルチノスタチン誘導体の非注射投与用組成物
US5389366A (en) * 1986-09-19 1995-02-14 Yamanouchi Pharmaceutical Co., Ltd. Neocarzinostatin derivative composition for oral administration
CA1327161C (en) * 1987-09-01 1994-02-22 Mitsugu Kobayashi Lyophilized pharmaceutical composition of neocarzinostatin derivative
EP1627645B1 (en) * 2003-05-26 2017-08-23 Hiroshi Maeda Antitumor agent and process for producing the same
JPWO2006080171A1 (ja) 2005-01-31 2008-06-19 株式会社 エフェクター細胞研究所 免疫増強剤
EP3072910A4 (en) 2013-11-19 2018-02-21 Hiroshi Maeda Derivative of styrene-maleic acid copolymer

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3085994A (en) * 1959-10-30 1963-04-16 Sinclair Research Inc Chain terminated copolymer of styrene and maleic anhydride of low solution viscosity
US3121043A (en) * 1960-05-11 1964-02-11 Scient Associates Inc Sustained release pharmaceutical preparation and methods for making same
US3245933A (en) * 1960-05-19 1966-04-12 Sinclair Research Inc Styrene-maleic anhydride copolymers cross-linked with aliphatic polyhydroxy compounds
JPS6017206B2 (ja) * 1977-03-24 1985-05-01 浩 前田 ネオカルチノスタチン誘導体の製造法
EP0087957B1 (en) * 1982-02-27 1986-11-26 Kuraray Co., Ltd. Neocarzinostatin complexes, a method for producing the same, and an antitumor agent containing said complexes as an active component

Also Published As

Publication number Publication date
EP0136792A2 (en) 1985-04-10
EP0136792B1 (en) 1989-06-14
DE3478689D1 (en) 1989-07-20
US4762885A (en) 1988-08-09
CA1241640A (en) 1988-09-06
EP0136792A3 (en) 1985-12-18
JPH0133120B2 (https=) 1989-07-11
JPS6075499A (ja) 1985-04-27

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee