DE3432584C2 - - Google Patents
Info
- Publication number
- DE3432584C2 DE3432584C2 DE19843432584 DE3432584A DE3432584C2 DE 3432584 C2 DE3432584 C2 DE 3432584C2 DE 19843432584 DE19843432584 DE 19843432584 DE 3432584 A DE3432584 A DE 3432584A DE 3432584 C2 DE3432584 C2 DE 3432584C2
- Authority
- DE
- Germany
- Prior art keywords
- ointment base
- agent
- use according
- acne
- cyproterone acetate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- UWFYSQMTEOIJJG-FDTZYFLXSA-N cyproterone acetate Chemical compound C1=C(Cl)C2=CC(=O)[C@@H]3C[C@@H]3[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@@](C(C)=O)(OC(=O)C)[C@@]1(C)CC2 UWFYSQMTEOIJJG-FDTZYFLXSA-N 0.000 claims description 19
- 229960000978 cyproterone acetate Drugs 0.000 claims description 14
- 239000003883 ointment base Substances 0.000 claims description 14
- 208000002874 Acne Vulgaris Diseases 0.000 claims description 12
- 206010000496 acne Diseases 0.000 claims description 12
- 239000003795 chemical substances by application Substances 0.000 claims description 12
- 239000004480 active ingredient Substances 0.000 claims description 8
- 230000000699 topical effect Effects 0.000 claims description 6
- 206010020112 Hirsutism Diseases 0.000 claims description 5
- 239000002674 ointment Substances 0.000 claims description 5
- SNPLKNRPJHDVJA-ZETCQYMHSA-N D-panthenol Chemical compound OCC(C)(C)[C@@H](O)C(=O)NCCCO SNPLKNRPJHDVJA-ZETCQYMHSA-N 0.000 claims description 4
- 229960003949 dexpanthenol Drugs 0.000 claims description 4
- 235000004866 D-panthenol Nutrition 0.000 claims description 3
- 239000011703 D-panthenol Substances 0.000 claims description 3
- 239000008312 unguentum emulsifican Substances 0.000 claims description 3
- 230000000694 effects Effects 0.000 description 5
- IAZDPXIOMUYVGZ-UHFFFAOYSA-N Dimethylsulphoxide Chemical compound CS(C)=O IAZDPXIOMUYVGZ-UHFFFAOYSA-N 0.000 description 4
- 238000002560 therapeutic procedure Methods 0.000 description 4
- 239000003981 vehicle Substances 0.000 description 4
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 description 3
- 229960003843 cyproterone Drugs 0.000 description 3
- 230000001225 therapeutic effect Effects 0.000 description 3
- 239000002202 Polyethylene glycol Substances 0.000 description 2
- 230000002280 anti-androgenic effect Effects 0.000 description 2
- 230000001815 facial effect Effects 0.000 description 2
- 238000000338 in vitro Methods 0.000 description 2
- 229920001223 polyethylene glycol Polymers 0.000 description 2
- 210000002374 sebum Anatomy 0.000 description 2
- 230000028327 secretion Effects 0.000 description 2
- 208000024891 symptom Diseases 0.000 description 2
- WILIRDQOEMCACO-BYZMTCBYSA-N (8s,9s,10r,13r,14s,17s)-17-ethyl-10,13-dimethyl-8,9,11,12,14,15,16,17-octahydro-3h-cyclopenta[a]phenanthrene Chemical compound C1=CC2=CCC=C[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H](CC)[C@@]1(C)CC2 WILIRDQOEMCACO-BYZMTCBYSA-N 0.000 description 1
- QTBSBXVTEAMEQO-UHFFFAOYSA-M Acetate Chemical compound CC([O-])=O QTBSBXVTEAMEQO-UHFFFAOYSA-M 0.000 description 1
- 239000004166 Lanolin Substances 0.000 description 1
- 206010039792 Seborrhoea Diseases 0.000 description 1
- 206010054786 Skin burning sensation Diseases 0.000 description 1
- 210000000577 adipose tissue Anatomy 0.000 description 1
- 239000000051 antiandrogen Substances 0.000 description 1
- 229940030495 antiandrogen sex hormone and modulator of the genital system Drugs 0.000 description 1
- 239000003433 contraceptive agent Substances 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 239000003995 emulsifying agent Substances 0.000 description 1
- 229940011871 estrogen Drugs 0.000 description 1
- 239000000262 estrogen Substances 0.000 description 1
- 230000003203 everyday effect Effects 0.000 description 1
- 235000013861 fat-free Nutrition 0.000 description 1
- 239000000499 gel Substances 0.000 description 1
- 229940088597 hormone Drugs 0.000 description 1
- 239000005556 hormone Substances 0.000 description 1
- 238000001727 in vivo Methods 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 231100000957 no side effect Toxicity 0.000 description 1
- 230000008506 pathogenesis Effects 0.000 description 1
- 230000035515 penetration Effects 0.000 description 1
- 235000019271 petrolatum Nutrition 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 208000008742 seborrheic dermatitis Diseases 0.000 description 1
- 150000003431 steroids Chemical class 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
- 229940124597 therapeutic agent Drugs 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/008—Preparations for oily skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/63—Steroids; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q7/00—Preparations for affecting hair growth
- A61Q7/02—Preparations for inhibiting or slowing hair growth
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Dermatology (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cosmetics (AREA)
Priority Applications (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19843432584 DE3432584A1 (de) | 1984-09-05 | 1984-09-05 | Mittel zur behandlung von hirsutismus und akne |
| PCT/DE1985/000307 WO1986001402A1 (en) | 1984-09-05 | 1985-08-30 | Means for handling androgenization phenomena and use of antiandrogens for the production thereof |
| AU48050/85A AU4805085A (en) | 1984-09-05 | 1985-08-30 | Mittel zur behandlung von androgenisierungserscheinungen und verwendung von antiandrogenen zur herstellung des mittels |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19843432584 DE3432584A1 (de) | 1984-09-05 | 1984-09-05 | Mittel zur behandlung von hirsutismus und akne |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE3432584A1 DE3432584A1 (de) | 1986-04-24 |
| DE3432584C2 true DE3432584C2 (enrdf_load_stackoverflow) | 1989-10-05 |
Family
ID=6244670
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE19843432584 Granted DE3432584A1 (de) | 1984-09-05 | 1984-09-05 | Mittel zur behandlung von hirsutismus und akne |
Country Status (1)
| Country | Link |
|---|---|
| DE (1) | DE3432584A1 (enrdf_load_stackoverflow) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19538555A1 (de) * | 1995-10-17 | 1997-04-24 | Beiersdorf Ag | Gegen Akne und entzündete Comedonen wirksame Wirkstoffkombinationen |
-
1984
- 1984-09-05 DE DE19843432584 patent/DE3432584A1/de active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| DE3432584A1 (de) | 1986-04-24 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE69518729T2 (de) | Stickstoffoxyd abgebendes präparat zur behandlung von analen erkrankungen | |
| DE3880769T2 (de) | Topische Behandlung von Störungen kranker Haut. | |
| EP0189738B1 (en) | Topical compositions for preventing or treating dry skin | |
| DE3621861A1 (de) | Verwendung von aryloxycarbonsaeure-derivaten gegen dermatologische erkrankungen | |
| EP0847279B1 (de) | Juckreizlindernde, kosmetische und/oder pharmazeutische zusammensetzungen bestehend aus einem oder mehreren leichten lokal anästhetika und einer oder mehreren adstringentien | |
| DE2747631C3 (de) | Salbe | |
| DE3836971C1 (enrdf_load_stackoverflow) | ||
| DE69822295T2 (de) | Verwendung von misoprostol und/oder misoprostolsäure zur behandlung von erektionsstörungen | |
| DE69430070T2 (de) | Topische pharmazeutische zusammensetzungen die (s)-2-(4-isobutylphenyl) propionsaeure enthalten | |
| DE19534209A1 (de) | Hormonales Mittel zur Behandlung der Haut | |
| CH695983A5 (de) | Tetraiodthyropropionsäure oder Tetraiodthyroessigsäure zur Herstellung eines dermatologischen Präparates. | |
| DE69804130T2 (de) | Verwendung eines gemischs aus einem diol und einer alpha-hydroxysäure zur behandlung hyperkeratotischer hauterkrankungen | |
| DE3411225C2 (enrdf_load_stackoverflow) | ||
| DE3603859A1 (de) | Abwaschbare topische zubereitung zur therapie der psoriasis | |
| DE1804801C3 (de) | Mittel zur Aknebehandlung | |
| WO1986001402A1 (en) | Means for handling androgenization phenomena and use of antiandrogens for the production thereof | |
| EP0316780B1 (de) | Verwendung von Ethisterone zur topischen Behandlung von Akne oder androgenetischer Alopezie | |
| EP1063998B1 (de) | Medikament zur prophylaxe und/oder behandlung des mammarkarzinoms enthaltend einen steroidalen aromataseinhibitor | |
| DE69300854T2 (de) | Mittel zur topischen Verabreichung von Spironolakton. | |
| WO1988000465A1 (en) | Use of dicarboxylic acids with 7-13 c atoms or their physiologically acceptable salts for the topical treatment of acne rosacea | |
| DE3432584C2 (enrdf_load_stackoverflow) | ||
| DE69005160T2 (de) | Verwendung von 5'-Deoxy-5'-methylthioadenosin, s-Adenylmethionin und deren Salzen zur Herstellung pharmazeutischer Präparate zur Förderung des Haarwuchses bei Patienten mit Kahlköpfigkeit. | |
| DD153759A5 (de) | Haarpflegemittel zur aeusseren anwendung | |
| EP0266303B1 (de) | Antigestagene zur Hemmung der uterinen Prostaglandinsynthese | |
| DE4319096C1 (de) | Hormonales Mittel zur Vorbeugung und Behandlung arterieller Erkrankungen beim Mann |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| OP8 | Request for examination as to paragraph 44 patent law | ||
| 8127 | New person/name/address of the applicant |
Owner name: ABDULLA, SOUHAIL, DR.MED., 2953 RHAUDERFEHN, DE |
|
| D2 | Grant after examination | ||
| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |