DE3379043D1 - Spiro-3-hetero-azolones for treatment of diabetic complications - Google Patents
Spiro-3-hetero-azolones for treatment of diabetic complicationsInfo
- Publication number
- DE3379043D1 DE3379043D1 DE8383307340T DE3379043T DE3379043D1 DE 3379043 D1 DE3379043 D1 DE 3379043D1 DE 8383307340 T DE8383307340 T DE 8383307340T DE 3379043 T DE3379043 T DE 3379043T DE 3379043 D1 DE3379043 D1 DE 3379043D1
- Authority
- DE
- Germany
- Prior art keywords
- azolones
- spiro
- hetero
- treatment
- diabetic complications
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US44733782A | 1982-12-06 | 1982-12-06 | |
| US06/545,450 US4556670A (en) | 1982-12-06 | 1983-10-28 | Spiro-3-hetero-azolones for treatment of diabetic complications |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE3379043D1 true DE3379043D1 (en) | 1989-03-02 |
Family
ID=27034944
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE8383307340T Expired DE3379043D1 (en) | 1982-12-06 | 1983-12-02 | Spiro-3-hetero-azolones for treatment of diabetic complications |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US4556670A (fi) |
| EP (1) | EP0115133B1 (fi) |
| KR (1) | KR860001581B1 (fi) |
| AU (1) | AU545409B2 (fi) |
| BG (1) | BG44708A3 (fi) |
| CA (1) | CA1204763A (fi) |
| DD (1) | DD219482A5 (fi) |
| DE (1) | DE3379043D1 (fi) |
| DK (1) | DK558283A (fi) |
| ES (1) | ES8601912A1 (fi) |
| FI (1) | FI80267C (fi) |
| GR (1) | GR78787B (fi) |
| IE (1) | IE56345B1 (fi) |
| IL (1) | IL70379A (fi) |
| NO (1) | NO160001C (fi) |
| NZ (1) | NZ206484A (fi) |
| PH (1) | PH19622A (fi) |
| PL (1) | PL142143B1 (fi) |
| PT (1) | PT77760B (fi) |
| RO (1) | RO88202B (fi) |
| YU (1) | YU43557B (fi) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0159143B1 (en) * | 1984-03-23 | 1987-12-16 | Pfizer Inc. | Spiro-indenes and spiro-1,2-dihydro-naphthalenes for treatment of diabetic complications |
| US4575507A (en) | 1985-05-29 | 1986-03-11 | Pfizer Inc. | Spiro-imidazolidines as aldose reductase inhibitors and their pharmaceutical use |
| GB8601100D0 (en) * | 1986-01-17 | 1986-02-19 | Cosmas Damian Ltd | Drug delivery system |
| GB2355264A (en) | 1999-09-30 | 2001-04-18 | Merck & Co Inc | Spirohydantoin derivatives useful as alpha 1a adrenoceptor antagonists |
| WO2003088915A2 (en) | 2002-04-18 | 2003-10-30 | University Of Virginia Patent Foundation | Novel sodium channel blockers |
| US20060116366A1 (en) * | 2002-12-04 | 2006-06-01 | Parmee Emma R | Spirocyclic ureas, compositions containing such compounds and methods of use |
| JO3501B1 (ar) * | 2014-12-22 | 2020-07-05 | Servier Lab | مشتقات 5-{(بيبرازين - 1-يل)-3-أوكسو - بروبيل}- إيميدازوليدين-2، 4 - دايون كمثبطات ل adamts لمعالجة هشاشة العظام) |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2872454A (en) * | 1959-02-03 | Spiro-hydantoins from x-chloro- | ||
| GB796069A (en) * | 1955-12-23 | 1958-06-04 | Ici Ltd | Substituted hydantoins |
| GB818724A (en) * | 1956-10-18 | 1959-08-19 | Ici Ltd | Hydantoin derivatives |
| US3532744A (en) * | 1967-07-28 | 1970-10-06 | American Home Prod | 1- and 2-amino substituted indane and tetralene carboxylic acids |
| US3985888A (en) * | 1969-07-24 | 1976-10-12 | Richardson-Merrell Inc. | Methods of inducing sedation using certain spiroalkanone-imides |
| US3821383A (en) * | 1972-07-10 | 1974-06-28 | Ayerst Mckenna & Harrison | Compositions for and a method of treating diabetic complications |
| US4117230A (en) * | 1976-10-18 | 1978-09-26 | Pfizer Inc. | Hydantoin derivatives as therapeutic agents |
| US4130714A (en) * | 1977-05-23 | 1978-12-19 | Pfizer Inc. | Hydantoin therapeutic agents |
| US4200642A (en) * | 1978-08-21 | 1980-04-29 | Pfizer Inc. | Spiro-oxazolidindiones |
| US4181729A (en) * | 1979-03-21 | 1980-01-01 | Pfizer Inc. | Phenyl or phenoxy substituted spiro-imidazolidinedione derivatives |
| US4226875A (en) * | 1979-04-02 | 1980-10-07 | Pfizer Inc. | Novel spiro-oxazolidinediones |
| US4307108A (en) * | 1979-12-26 | 1981-12-22 | Pfizer Inc. | Method for lowering sorbitol levels using spiro-imides |
| US4248882A (en) * | 1980-02-12 | 1981-02-03 | Pfizer Inc. | Treating diabetes-associated complications with hydantoin amines |
| JPS5745185A (en) * | 1980-07-21 | 1982-03-13 | Eisai Co Ltd | Hydantoin derivative and its preparation |
-
1983
- 1983-10-28 US US06/545,450 patent/US4556670A/en not_active Expired - Fee Related
- 1983-11-30 PT PT77760A patent/PT77760B/pt not_active IP Right Cessation
- 1983-12-01 RO RO112721A patent/RO88202B/ro unknown
- 1983-12-02 NO NO834437A patent/NO160001C/no unknown
- 1983-12-02 DE DE8383307340T patent/DE3379043D1/de not_active Expired
- 1983-12-02 EP EP83307340A patent/EP0115133B1/en not_active Expired
- 1983-12-02 CA CA000442457A patent/CA1204763A/en not_active Expired
- 1983-12-05 ES ES527780A patent/ES8601912A1/es not_active Expired
- 1983-12-05 AU AU21968/83A patent/AU545409B2/en not_active Ceased
- 1983-12-05 BG BG063307A patent/BG44708A3/xx unknown
- 1983-12-05 IL IL70379A patent/IL70379A/xx unknown
- 1983-12-05 KR KR1019830005781A patent/KR860001581B1/ko not_active IP Right Cessation
- 1983-12-05 DK DK558283A patent/DK558283A/da not_active Application Discontinuation
- 1983-12-05 GR GR73158A patent/GR78787B/el unknown
- 1983-12-05 YU YU2371/83A patent/YU43557B/xx unknown
- 1983-12-05 PH PH29927A patent/PH19622A/en unknown
- 1983-12-05 NZ NZ206484A patent/NZ206484A/en unknown
- 1983-12-05 IE IE2854/83A patent/IE56345B1/en not_active IP Right Cessation
- 1983-12-05 FI FI834457A patent/FI80267C/fi not_active IP Right Cessation
- 1983-12-06 DD DD83257566A patent/DD219482A5/de not_active IP Right Cessation
- 1983-12-06 PL PL1983244966A patent/PL142143B1/pl unknown
Also Published As
| Publication number | Publication date |
|---|---|
| FI834457A (fi) | 1984-06-07 |
| CA1204763A (en) | 1986-05-20 |
| IE832854L (en) | 1984-06-06 |
| YU43557B (en) | 1989-08-31 |
| ES527780A0 (es) | 1985-11-16 |
| US4556670A (en) | 1985-12-03 |
| NO834437L (no) | 1984-06-07 |
| PL244966A1 (en) | 1985-05-21 |
| DK558283A (da) | 1984-07-11 |
| RO88202B (ro) | 1985-12-31 |
| GR78787B (fi) | 1984-10-02 |
| AU545409B2 (en) | 1985-07-11 |
| NZ206484A (en) | 1987-07-31 |
| NO160001B (no) | 1988-11-21 |
| EP0115133A1 (en) | 1984-08-08 |
| PL142143B1 (en) | 1987-09-30 |
| IL70379A0 (en) | 1984-03-30 |
| FI80267C (fi) | 1990-05-10 |
| YU237183A (en) | 1986-02-28 |
| FI80267B (fi) | 1990-01-31 |
| PT77760B (en) | 1986-05-30 |
| DD219482A5 (de) | 1985-03-06 |
| IL70379A (en) | 1988-10-31 |
| NO160001C (no) | 1989-03-01 |
| DK558283D0 (da) | 1983-12-05 |
| PH19622A (en) | 1986-05-30 |
| BG44708A3 (bg) | 1989-01-16 |
| KR860001581B1 (ko) | 1986-10-10 |
| IE56345B1 (en) | 1991-07-03 |
| EP0115133B1 (en) | 1989-01-25 |
| PT77760A (en) | 1983-12-01 |
| ES8601912A1 (es) | 1985-11-16 |
| KR840006975A (ko) | 1984-12-04 |
| FI834457A0 (fi) | 1983-12-05 |
| RO88202A (ro) | 1985-12-30 |
| AU2196883A (en) | 1984-06-14 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |