DE3366505D1 - Glycosides isolated from the euphorbiaceae genus phyllanthus and their anti-tumour use - Google Patents

Glycosides isolated from the euphorbiaceae genus phyllanthus and their anti-tumour use

Info

Publication number
DE3366505D1
DE3366505D1 DE8383300600T DE3366505T DE3366505D1 DE 3366505 D1 DE3366505 D1 DE 3366505D1 DE 8383300600 T DE8383300600 T DE 8383300600T DE 3366505 T DE3366505 T DE 3366505T DE 3366505 D1 DE3366505 D1 DE 3366505D1
Authority
DE
Germany
Prior art keywords
euphorbiaceae
glycosides isolated
genus phyllanthus
tumour
tumour use
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8383300600T
Other languages
German (de)
English (en)
Inventor
George Robert Pettit
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University Patents Inc
Original Assignee
University Patents Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University Patents Inc filed Critical University Patents Inc
Application granted granted Critical
Publication of DE3366505D1 publication Critical patent/DE3366505D1/de
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/47—Euphorbiaceae (Spurge family), e.g. Ricinus (castorbean)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/10—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals directly attached to heterocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/01—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing oxygen

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Mycology (AREA)
  • Botany (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Medical Informatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
DE8383300600T 1982-02-11 1983-02-07 Glycosides isolated from the euphorbiaceae genus phyllanthus and their anti-tumour use Expired DE3366505D1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/348,114 US4388457A (en) 1982-02-11 1982-02-11 Phyllanthostatin compounds

Publications (1)

Publication Number Publication Date
DE3366505D1 true DE3366505D1 (en) 1986-11-06

Family

ID=23366697

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8383300600T Expired DE3366505D1 (en) 1982-02-11 1983-02-07 Glycosides isolated from the euphorbiaceae genus phyllanthus and their anti-tumour use

Country Status (4)

Country Link
US (1) US4388457A (enExample)
EP (1) EP0087861B1 (enExample)
JP (1) JPS58148891A (enExample)
DE (1) DE3366505D1 (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0173480A3 (en) * 1984-08-30 1987-09-16 The Upjohn Company The antiviral use of phyllanthostatins
CA1291036C (en) * 1986-04-23 1991-10-22 Edwin I. Stoltz Nasal administration of drugs
DE3705151A1 (de) * 1987-02-18 1988-09-01 Brigitte Luenemann Warzenmittel
US4997817A (en) * 1990-01-19 1991-03-05 Arizona Board Of Reagents Phyllanthostatin A
DE19919585A1 (de) 1999-04-29 2000-12-07 Cmi Ag Verwendung von Phyllanthus zur Behandlung von oxidativem Streß und anderen Symptomen
DE10030139A1 (de) * 2000-06-20 2002-01-10 Cmi Ag Verwendung von Phyllanthusbesandteilen zur Behandlung oder Prophylaxe von Infekten durch Flaviviridae
ATE275413T1 (de) * 2000-10-06 2004-09-15 Phytrix Ag Verfahren zur herstellung von phyllanthusextrakten
EP1333848B1 (en) * 2000-10-06 2006-04-05 Phytrix AG Phyllanthus-derived compounds for the prevention and/or treatment of diseases associated with a retrovirus
DE10120627A1 (de) * 2001-04-26 2002-10-31 Cmi Ag Verwendung von Phyllanthusbestandteilen zur Behandlung oder Prophylaxe von Infekten durch Hepatitis B-Viren
CN103880856B (zh) * 2014-04-11 2017-01-04 中国科学院昆明植物研究所 没药烷型倍半萜类衍生物及其药物组合物和其在制药中的应用
US20180030095A1 (en) 2015-02-13 2018-02-01 George Robert Pettit Silstatin compounds
WO2019094709A1 (en) 2017-11-09 2019-05-16 Pettit George R Betulastatin compounds

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1451798A (en) * 1973-08-02 1976-10-06 Ici Ltd Prostanoic acid derivatives
FI67386C (fi) * 1979-06-21 1985-03-11 Hoffmann La Roche Foerfarande foer framstaellning av nya terapeutiskt anvaendbara sockerderivat

Also Published As

Publication number Publication date
JPH0457678B2 (enExample) 1992-09-14
JPS58148891A (ja) 1983-09-05
US4388457A (en) 1983-06-14
EP0087861A1 (en) 1983-09-07
EP0087861B1 (en) 1986-10-01

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee