DE3361112D1 - Process and plant for fractionating mixtures by elution chromatography with a supercritical fluid phase - Google Patents

Process and plant for fractionating mixtures by elution chromatography with a supercritical fluid phase

Info

Publication number
DE3361112D1
DE3361112D1 DE8383401040T DE3361112T DE3361112D1 DE 3361112 D1 DE3361112 D1 DE 3361112D1 DE 8383401040 T DE8383401040 T DE 8383401040T DE 3361112 T DE3361112 T DE 3361112T DE 3361112 D1 DE3361112 D1 DE 3361112D1
Authority
DE
Germany
Prior art keywords
elution chromatography
plant
supercritical fluid
fluid phase
fractionating mixtures
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8383401040T
Other languages
German (de)
English (en)
Inventor
Michel Perrut
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Societe National Elf Aquitaine
Original Assignee
Societe National Elf Aquitaine
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Societe National Elf Aquitaine filed Critical Societe National Elf Aquitaine
Application granted granted Critical
Publication of DE3361112D1 publication Critical patent/DE3361112D1/de
Expired legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/40—Selective adsorption, e.g. chromatography characterised by the separation mechanism using supercritical fluid as mobile phase or eluent
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C7/00—Purification; Separation; Use of additives
    • C07C7/12—Purification; Separation; Use of additives by adsorption, i.e. purification or separation of hydrocarbons with the aid of solids, e.g. with ion-exchangers
    • C07C7/13—Purification; Separation; Use of additives by adsorption, i.e. purification or separation of hydrocarbons with the aid of solids, e.g. with ion-exchangers by molecular-sieve technique
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/26—Conditioning of the fluid carrier; Flow patterns
    • G01N30/28—Control of physical parameters of the fluid carrier
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/26—Conditioning of the fluid carrier; Flow patterns
    • G01N30/28—Control of physical parameters of the fluid carrier
    • G01N30/34—Control of physical parameters of the fluid carrier of fluid composition, e.g. gradient
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/62—Detectors specially adapted therefor
    • G01N2030/621—Detectors specially adapted therefor signal-to-noise ratio
    • G01N2030/623—Detectors specially adapted therefor signal-to-noise ratio by modulation of sample feed or detector response
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/26—Conditioning of the fluid carrier; Flow patterns
    • G01N30/38—Flow patterns
    • G01N30/44—Flow patterns using recycling of the fraction to be distributed
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/80—Fraction collectors
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/54—Improvements relating to the production of bulk chemicals using solvents, e.g. supercritical solvents or ionic liquids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Organic Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Water Supply & Treatment (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE8383401040T 1982-06-03 1983-05-25 Process and plant for fractionating mixtures by elution chromatography with a supercritical fluid phase Expired DE3361112D1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8209649A FR2527934A1 (fr) 1982-06-03 1982-06-03 Procede de fractionnement de melanges par chromatographie d'elution avec fluide en etat supercritique et installation pour sa mise en oeuvre

Publications (1)

Publication Number Publication Date
DE3361112D1 true DE3361112D1 (en) 1985-12-05

Family

ID=9274587

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8383401040T Expired DE3361112D1 (en) 1982-06-03 1983-05-25 Process and plant for fractionating mixtures by elution chromatography with a supercritical fluid phase

Country Status (7)

Country Link
US (1) US4478720A (enExample)
EP (1) EP0099765B1 (enExample)
JP (1) JPS5917157A (enExample)
AT (1) ATE16247T1 (enExample)
CA (1) CA1202913A (enExample)
DE (1) DE3361112D1 (enExample)
FR (1) FR2527934A1 (enExample)

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JPS60241908A (ja) * 1984-05-15 1985-11-30 Morinaga & Co Ltd 多成分系原料より精製成分を製造する方法
JPH0664032B2 (ja) * 1985-10-12 1994-08-22 出光石油化学株式会社 超臨界流体による混合物からの特定成分の分離方法
JPS62138753A (ja) * 1985-12-12 1987-06-22 Hitachi Ltd 液体クロマトグラフイによる分画・分取方法および装置
JPS62155908A (ja) * 1985-12-28 1987-07-10 Idemitsu Petrochem Co Ltd 超臨界流体による水／アルコ−ル混合物の分離方法
JPS62192028A (ja) * 1986-02-18 1987-08-22 Hitachi Maxell Ltd 磁気記録媒体
US4681678A (en) * 1986-10-10 1987-07-21 Combustion Engineering, Inc. Sample dilution system for supercritical fluid chromatography
US4684465A (en) * 1986-10-10 1987-08-04 Combustion Engineering, Inc. Supercritical fluid chromatograph with pneumatically controlled pump
US4859342A (en) * 1986-10-14 1989-08-22 Suntory Limited Process for industrially separating biopolymers
DE3717456C1 (de) * 1987-05-23 1988-07-21 Eberhard Gerstel Gaschromatograph und Verfahren zur gaschromatographischen Trennung
US4880543A (en) * 1987-08-31 1989-11-14 Aluminum Company Of America Supercritical fluid chromatography packing material containing alumina
US4816159A (en) * 1987-08-31 1989-03-28 Aluminum Company Of America Supercritical fluid chromatography packing material
US5180487A (en) * 1987-09-25 1993-01-19 Nihon Bunko Kogyo Kabushiki Kaisha Pump apparatus for transferring a liquified gas used in a recycle chromatograph
JPS6483152A (en) * 1987-09-25 1989-03-28 Japan Spectroscopic Co Recycling chromatograph
DE3863891D1 (de) * 1987-10-08 1991-08-29 Givaudan & Cie Sa Vorrichtung zum verzweigen von gasstroemen.
US5169522A (en) * 1990-09-25 1992-12-08 Ht Chemicals, Inc. Column slurry packing compressor
US5234599A (en) * 1990-10-09 1993-08-10 The Dow Chemical Company On-line multidimensional chromatographic system with large volume injection handling for supercritical fluid chromatography
ATE130209T1 (de) * 1990-10-09 1995-12-15 Dow Chemical Co Multidimensionales on-line chromatographiesystem für die überkritische fluidchromatographie.
US5139681A (en) * 1990-10-09 1992-08-18 The Dow Chemical Company On-line multidimensional chromatographic system with large volume injection handling for supercritical fluid chromatography
US5372716A (en) * 1991-02-28 1994-12-13 Suprex Corporation Supercritical fluid extraction coupled to analytical chromatography system
ATE151880T1 (de) * 1991-06-26 1997-05-15 Perseptive Biosystems Inc Verfahren und vorrichtung zum nachweis von kontaminationsspuren
FR2694208B1 (fr) * 1992-07-30 1994-09-23 Separex Sa Procédé et dispositif industriels de fractionnement de mélanges de composants par chromatographie.
FR2690630B1 (fr) * 1992-04-29 1994-07-22 Separex Sa Procede et dispositif de fractionnement de melanges de composants par voie chromatographique a l'aide d'un eluant a pression supercritique.
DE69323382T2 (de) * 1992-04-29 1999-06-10 Institut Francais Du Petrole, Rueil-Malmaison, Hauts-De-Seine Verfahren und vorrichtung zur chromatographischen fraktionierung einer mischung mittels eines simulierten fliessbetts in gegenwart eines komprimierten gases, eines überkritischem fluides oder einer unterkritischen flüssigkeit
US5458783A (en) * 1992-08-13 1995-10-17 Suprex Corporation Supercritical fluid extraction coupled to analytical chromatography system
US5346622A (en) * 1993-03-04 1994-09-13 Hewlett-Packard Company Hydrocarbon class separation and quantitation by split column effluent analysis
US5470377A (en) * 1993-03-08 1995-11-28 Whitlock; David R. Separation of solutes in gaseous solvents
JPH08512336A (ja) * 1993-04-29 1996-12-24 ノルスク・ヒドロ・アクシェセルスカープ 脂肪酸およびその誘導体のクロマトグラフィーによる分画方法
FI102758B (fi) * 1995-03-03 1999-02-15 Santen Pharmaceutical Co Ltd Menetelmä puhtaan syklosporiinimuodon valmistamiseksi
US5630943A (en) * 1995-11-30 1997-05-20 Merck Patent Gesellschaft Mit Beschrankter Haftung Discontinuous countercurrent chromatographic process and apparatus
US6063284A (en) * 1997-05-15 2000-05-16 Em Industries, Inc. Single column closed-loop recycling with periodic intra-profile injection
US6048369A (en) * 1998-06-03 2000-04-11 North Carolina State University Method of dyeing hydrophobic textile fibers with colorant materials in supercritical fluid carbon dioxide
US6413428B1 (en) 1999-09-16 2002-07-02 Berger Instruments, Inc. Apparatus and method for preparative supercritical fluid chromatography
US6685828B2 (en) 1999-09-16 2004-02-03 Berger Instruments, Inc. Automated sample collection in supercritical fluid chromatography
US6261326B1 (en) 2000-01-13 2001-07-17 North Carolina State University Method for introducing dyes and other chemicals into a textile treatment system
US6558540B2 (en) * 2000-06-26 2003-05-06 Berger Instruments, Inc. Exhaust gas collection system for supercritical fluid chromatography
US6632353B2 (en) 2000-06-26 2003-10-14 Berger Instruments, Inc. Rapid sample collection in supercritical fluid chromatography
US6676710B2 (en) 2000-10-18 2004-01-13 North Carolina State University Process for treating textile substrates
US6601438B2 (en) 2001-09-28 2003-08-05 Systec, Inc. Apparatus for conducting high-temperature liquid chromotography analysis
US6802967B2 (en) * 2002-03-06 2004-10-12 Shimadzu Corporation Multi-dimension liquid chromatography separation system
JP2003347624A (ja) * 2002-05-27 2003-12-05 Konica Minolta Holdings Inc 有機半導体材料の精製方法、該精製方法を用いて得られた有機半導体材料及びそれを用いた半導体素子
US6908557B2 (en) * 2002-06-25 2005-06-21 Thar Technologies, Inc. Collection system for chromatographic system
SE0202188D0 (sv) 2002-07-11 2002-07-11 Pronova Biocare As A process for decreasing environmental pollutants in an oil or a fat, a volatile fat or oil environmental pollutants decreasing working fluid, a health supplement, and an animal feed product
EP2295529B2 (en) 2002-07-11 2022-05-18 Basf As Use of a volatile environmental pollutants-decreasing working fluid for decreasing the amount of pollutants in a fat for alimentary or cosmetic use
DE60341314C5 (de) * 2003-12-09 2023-03-23 The Regents Of The University Of California Hocheffiziente leuchtdioden auf galliumnitridbasis mit oberflächenaufrauhung
JP4319551B2 (ja) 2004-01-05 2009-08-26 ダイセル化学工業株式会社 超臨界流体クロマトグラフィーによる物質の分離方法及びこれに用いられる気液分離装置
US20060188397A1 (en) * 2005-01-07 2006-08-24 Lalit Chordia Method and apparatus for fraction collection
FR2882528B1 (fr) * 2005-02-25 2007-05-25 Pic Solution Soc Par Actions S Procede mixte de chromatographie en phase supercritique et installation pour sa mise en oeuvre
FR2889665B1 (fr) 2005-08-12 2007-11-09 Pic Solution Soc Par Actions S Procede et installation pour la regulation du taux de modificateur dans une chromatographie ou extraction supercritique avec recyclage
FR2897277B1 (fr) * 2006-02-10 2008-04-18 Novasep Soc Par Actions Simpli Procede et dispositif de separation.
US20080053908A1 (en) * 2006-09-01 2008-03-06 Lalit Chordia High pressure flash chromatography
KR100925919B1 (ko) * 2008-01-04 2009-11-09 창원대학교 산학협력단 압축공기를 이용한 베어링의 가변예압장치 및 방법
US8215922B2 (en) 2008-06-24 2012-07-10 Aurora Sfc Systems, Inc. Compressible fluid pumping system for dynamically compensating compressible fluids over large pressure ranges
US9163618B2 (en) 2008-06-24 2015-10-20 Agilent Technologies, Inc. Automated conversion between SFC and HPLC
EP2344873B1 (en) * 2008-11-12 2018-05-30 Waters Technologies Corporation Collection system for purification flowstreams
US8419936B2 (en) 2010-03-23 2013-04-16 Agilent Technologies, Inc. Low noise back pressure regulator for supercritical fluid chromatography
US10376814B2 (en) 2015-01-30 2019-08-13 Agilent Technologies, Inc. Impact centrifugal separator and associated methods for fraction collection in supercritical fluid systems
WO2018073500A1 (fr) * 2016-10-21 2018-04-26 Novasep Process Utilisation de gaz comprimé pour le déplacement d'éluant appliqué à la chromatographie
US20230075933A1 (en) * 2021-09-09 2023-03-09 Dionex Corporation Check standard recycle setup for ion chromatography
CN114272646B (zh) * 2021-12-30 2025-09-09 江苏汉邦科技股份有限公司 一种高效率超临界设备

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GB1350580A (en) * 1970-05-28 1974-04-18 British Petroleum Co Gas chromatography
DE2729462A1 (de) * 1977-06-30 1979-01-18 Wolfgang Dr Hartmann Vorrichtung und verfahren zur chromatographischen trennung von substanzen geringen dampfdrucks

Also Published As

Publication number Publication date
JPS5917157A (ja) 1984-01-28
US4478720A (en) 1984-10-23
FR2527934A1 (fr) 1983-12-09
FR2527934B1 (enExample) 1984-12-07
ATE16247T1 (de) 1985-11-15
EP0099765A1 (fr) 1984-02-01
JPH0248061B2 (enExample) 1990-10-23
CA1202913A (en) 1986-04-08
EP0099765B1 (fr) 1985-10-30

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Legal Events

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