DE3361013D1 - A novel ester of the 1-methyl-5-p-toluoylpyrrolyl-2-acetic acid having antiinflammatory, mucolytic and antitussive properties, process for its preparation and pharmaceutical compositions containing them - Google Patents

A novel ester of the 1-methyl-5-p-toluoylpyrrolyl-2-acetic acid having antiinflammatory, mucolytic and antitussive properties, process for its preparation and pharmaceutical compositions containing them

Info

Publication number
DE3361013D1
DE3361013D1 DE8383830046T DE3361013T DE3361013D1 DE 3361013 D1 DE3361013 D1 DE 3361013D1 DE 8383830046 T DE8383830046 T DE 8383830046T DE 3361013 T DE3361013 T DE 3361013T DE 3361013 D1 DE3361013 D1 DE 3361013D1
Authority
DE
Germany
Prior art keywords
methyl
acetic acid
mucolytic
antiinflammatory
toluoylpyrrolyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8383830046T
Other languages
English (en)
Inventor
Alessandro Baglioni
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Medosan Industrie Biochimiche Riunite SpA
Original Assignee
Medosan Industrie Biochimiche Riunite SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medosan Industrie Biochimiche Riunite SpA filed Critical Medosan Industrie Biochimiche Riunite SpA
Application granted granted Critical
Publication of DE3361013D1 publication Critical patent/DE3361013D1/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/33—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/337—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyrrole Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Hydrogenated Pyridines (AREA)
DE8383830046T 1982-03-05 1983-03-02 A novel ester of the 1-methyl-5-p-toluoylpyrrolyl-2-acetic acid having antiinflammatory, mucolytic and antitussive properties, process for its preparation and pharmaceutical compositions containing them Expired DE3361013D1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT47938/82A IT1148117B (it) 1982-03-05 1982-03-05 Attivita'antiflogistica,analgesica,antipiretica,mucolitica e seda tiva della tosse dell'1 metil-5-p-tolilpirrol-2-acetato di 2'metossi-fenile

Publications (1)

Publication Number Publication Date
DE3361013D1 true DE3361013D1 (en) 1985-11-21

Family

ID=11263480

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8383830046T Expired DE3361013D1 (en) 1982-03-05 1983-03-02 A novel ester of the 1-methyl-5-p-toluoylpyrrolyl-2-acetic acid having antiinflammatory, mucolytic and antitussive properties, process for its preparation and pharmaceutical compositions containing them

Country Status (6)

Country Link
US (1) US4521538A (de)
EP (1) EP0088734B1 (de)
AT (1) ATE16100T1 (de)
DE (1) DE3361013D1 (de)
ES (1) ES8404326A1 (de)
IT (1) IT1148117B (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1210673B (it) * 1982-02-26 1989-09-20 Medosan Ind Biochimi Antinfiammatoria amidi pirrolacetiche ad attivita'
IT1197688B (it) * 1983-07-29 1988-12-06 Medosan Ind Biochimi Attivita' antiflogistica,analgesica,antipiretica ed antiaggregante piastrinica di 1-metil-5-metilbenzoilpirrol-2-acetamido acetanilidi
US5648358A (en) * 1996-03-05 1997-07-15 Mitra; Sekhar Compositions and methods for treating respiratory disorders
IT1297140B1 (it) 1997-12-24 1999-08-03 Sigma Tau Ind Farmaceuti Forma cristallina del guaiacil estere dell'acido l-metil-5-p-toluoil- pirrol-2-acetammidoacetico, procedimento per la sua preparazione e
JP4143218B2 (ja) * 1999-04-23 2008-09-03 株式会社日本触媒 薄膜式蒸発装置における重合防止方法および薄膜式蒸発装置
WO2003043968A1 (en) * 2001-11-20 2003-05-30 Mitsubishi Chemical Corporation Process for producing (meth)acrylic acid compounds

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3752826A (en) * 1970-01-26 1973-08-14 Mcneilab Inc Aroyl substituted pyrroles
EP0006845B1 (de) * 1978-07-10 1982-02-03 McNeilab, Inc. Ein pharmazeutisches Präparat enthaltend ein Derivat einer 5-Aroyl-1-C1-5 alkyl-pyrrol-2-Essigsäure und Acetaminophen oder Acetylsalicylsäure
US4284785A (en) * 1979-12-19 1981-08-18 American Cyanamid Company Substituted phenyl esters of isoxazolecarboxylic acids
US4396626A (en) * 1980-10-09 1983-08-02 Beecham Group Limited Cyclic compounds and their use
ES8200092A1 (es) * 1980-11-11 1981-10-16 Calzada & Co Procedimiento para la sintesis de esteres de la n-(4'hidro- xifenil) acetamida con acidos 5-benzoil-1-metilpirrol-2-ace-tico

Also Published As

Publication number Publication date
IT1148117B (it) 1986-11-26
IT8247938A0 (it) 1982-03-05
US4521538A (en) 1985-06-04
ES520319A0 (es) 1984-04-16
ES8404326A1 (es) 1984-04-16
EP0088734B1 (de) 1985-10-16
ATE16100T1 (de) 1985-11-15
EP0088734A1 (de) 1983-09-14

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee