DE3361013D1 - A novel ester of the 1-methyl-5-p-toluoylpyrrolyl-2-acetic acid having antiinflammatory, mucolytic and antitussive properties, process for its preparation and pharmaceutical compositions containing them - Google Patents
A novel ester of the 1-methyl-5-p-toluoylpyrrolyl-2-acetic acid having antiinflammatory, mucolytic and antitussive properties, process for its preparation and pharmaceutical compositions containing themInfo
- Publication number
- DE3361013D1 DE3361013D1 DE8383830046T DE3361013T DE3361013D1 DE 3361013 D1 DE3361013 D1 DE 3361013D1 DE 8383830046 T DE8383830046 T DE 8383830046T DE 3361013 T DE3361013 T DE 3361013T DE 3361013 D1 DE3361013 D1 DE 3361013D1
- Authority
- DE
- Germany
- Prior art keywords
- methyl
- acetic acid
- mucolytic
- antiinflammatory
- toluoylpyrrolyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/33—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/337—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pyrrole Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT47938/82A IT1148117B (it) | 1982-03-05 | 1982-03-05 | Attivita'antiflogistica,analgesica,antipiretica,mucolitica e seda tiva della tosse dell'1 metil-5-p-tolilpirrol-2-acetato di 2'metossi-fenile |
Publications (1)
Publication Number | Publication Date |
---|---|
DE3361013D1 true DE3361013D1 (en) | 1985-11-21 |
Family
ID=11263480
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE8383830046T Expired DE3361013D1 (en) | 1982-03-05 | 1983-03-02 | A novel ester of the 1-methyl-5-p-toluoylpyrrolyl-2-acetic acid having antiinflammatory, mucolytic and antitussive properties, process for its preparation and pharmaceutical compositions containing them |
Country Status (6)
Country | Link |
---|---|
US (1) | US4521538A (de) |
EP (1) | EP0088734B1 (de) |
AT (1) | ATE16100T1 (de) |
DE (1) | DE3361013D1 (de) |
ES (1) | ES8404326A1 (de) |
IT (1) | IT1148117B (de) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1210673B (it) * | 1982-02-26 | 1989-09-20 | Medosan Ind Biochimi | Antinfiammatoria amidi pirrolacetiche ad attivita' |
IT1197688B (it) * | 1983-07-29 | 1988-12-06 | Medosan Ind Biochimi | Attivita' antiflogistica,analgesica,antipiretica ed antiaggregante piastrinica di 1-metil-5-metilbenzoilpirrol-2-acetamido acetanilidi |
US5648358A (en) * | 1996-03-05 | 1997-07-15 | Mitra; Sekhar | Compositions and methods for treating respiratory disorders |
IT1297140B1 (it) | 1997-12-24 | 1999-08-03 | Sigma Tau Ind Farmaceuti | Forma cristallina del guaiacil estere dell'acido l-metil-5-p-toluoil- pirrol-2-acetammidoacetico, procedimento per la sua preparazione e |
JP4143218B2 (ja) * | 1999-04-23 | 2008-09-03 | 株式会社日本触媒 | 薄膜式蒸発装置における重合防止方法および薄膜式蒸発装置 |
WO2003043968A1 (en) * | 2001-11-20 | 2003-05-30 | Mitsubishi Chemical Corporation | Process for producing (meth)acrylic acid compounds |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3752826A (en) * | 1970-01-26 | 1973-08-14 | Mcneilab Inc | Aroyl substituted pyrroles |
EP0006845B1 (de) * | 1978-07-10 | 1982-02-03 | McNeilab, Inc. | Ein pharmazeutisches Präparat enthaltend ein Derivat einer 5-Aroyl-1-C1-5 alkyl-pyrrol-2-Essigsäure und Acetaminophen oder Acetylsalicylsäure |
US4284785A (en) * | 1979-12-19 | 1981-08-18 | American Cyanamid Company | Substituted phenyl esters of isoxazolecarboxylic acids |
US4396626A (en) * | 1980-10-09 | 1983-08-02 | Beecham Group Limited | Cyclic compounds and their use |
ES8200092A1 (es) * | 1980-11-11 | 1981-10-16 | Calzada & Co | Procedimiento para la sintesis de esteres de la n-(4'hidro- xifenil) acetamida con acidos 5-benzoil-1-metilpirrol-2-ace-tico |
-
1982
- 1982-03-05 IT IT47938/82A patent/IT1148117B/it active
-
1983
- 1983-03-02 EP EP83830046A patent/EP0088734B1/de not_active Expired
- 1983-03-02 AT AT83830046T patent/ATE16100T1/de not_active IP Right Cessation
- 1983-03-02 DE DE8383830046T patent/DE3361013D1/de not_active Expired
- 1983-03-04 US US06/472,255 patent/US4521538A/en not_active Expired - Fee Related
- 1983-03-04 ES ES520319A patent/ES8404326A1/es not_active Expired
Also Published As
Publication number | Publication date |
---|---|
IT1148117B (it) | 1986-11-26 |
IT8247938A0 (it) | 1982-03-05 |
US4521538A (en) | 1985-06-04 |
ES520319A0 (es) | 1984-04-16 |
ES8404326A1 (es) | 1984-04-16 |
EP0088734B1 (de) | 1985-10-16 |
ATE16100T1 (de) | 1985-11-15 |
EP0088734A1 (de) | 1983-09-14 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |