DE3271829D1 - An allergen dry powder composition and process for its preparation - Google Patents

An allergen dry powder composition and process for its preparation

Info

Publication number
DE3271829D1
DE3271829D1 DE8282830117T DE3271829T DE3271829D1 DE 3271829 D1 DE3271829 D1 DE 3271829D1 DE 8282830117 T DE8282830117 T DE 8282830117T DE 3271829 T DE3271829 T DE 3271829T DE 3271829 D1 DE3271829 D1 DE 3271829D1
Authority
DE
Germany
Prior art keywords
allergen
preparation
dry powder
powder composition
choconstritive
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8282830117T
Other languages
German (de)
English (en)
Inventor
Gaetano Melillo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Lofarma SpA
Original Assignee
Laboratorio Farmaceutico Lofarma Sas
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratorio Farmaceutico Lofarma Sas filed Critical Laboratorio Farmaceutico Lofarma Sas
Application granted granted Critical
Publication of DE3271829D1 publication Critical patent/DE3271829D1/de
Expired legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/35Allergens

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Immunology (AREA)
  • Otolaryngology (AREA)
  • Pulmonology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DE8282830117T 1981-06-04 1982-04-29 An allergen dry powder composition and process for its preparation Expired DE3271829D1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT22136/81A IT1220979B (it) 1981-06-04 1981-06-04 Capsule contenenti un allergene e procedimento per la loro preparazione

Publications (1)

Publication Number Publication Date
DE3271829D1 true DE3271829D1 (en) 1986-07-31

Family

ID=11192020

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8282830117T Expired DE3271829D1 (en) 1981-06-04 1982-04-29 An allergen dry powder composition and process for its preparation

Country Status (13)

Country Link
US (1) US4681752A (enExample)
EP (1) EP0067130B1 (enExample)
JP (1) JPS57212114A (enExample)
AT (1) ATE20518T1 (enExample)
CA (1) CA1207663A (enExample)
CH (1) CH650925A5 (enExample)
DE (1) DE3271829D1 (enExample)
DK (1) DK153920C (enExample)
FR (1) FR2512670B1 (enExample)
GR (1) GR76810B (enExample)
IL (1) IL65875A (enExample)
IT (1) IT1220979B (enExample)
NO (1) NO156275C (enExample)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5075109A (en) * 1986-10-24 1991-12-24 Southern Research Institute Method of potentiating an immune response
US6024983A (en) * 1986-10-24 2000-02-15 Southern Research Institute Composition for delivering bioactive agents for immune response and its preparation
US5204113A (en) * 1987-04-09 1993-04-20 Fisons Plc Pharmaceutical compositions containing pentamidine
JP2770970B2 (ja) * 1987-04-09 1998-07-02 フアイソンズ・ピーエルシー ペンタミジンを含有する医薬組成物
US5021554A (en) * 1989-02-24 1991-06-04 Eli Lilly And Company Process for protein particle size reduction using a fluid-energy mill
WO1992016554A1 (en) * 1991-03-14 1992-10-01 The University Of Melbourne Protein allergens of the species cynodon dactylon
WO1993006862A1 (en) * 1991-10-11 1993-04-15 Toray Industries, Inc. Antibody composition
US5641510A (en) * 1994-07-01 1997-06-24 Genentech, Inc. Method for treating capsules used for drug storage
EP0711804A3 (de) 1994-11-14 1999-09-22 Ciba SC Holding AG Kryptolichtschutzmittel
ATE247948T1 (de) * 1996-04-29 2003-09-15 Dura Pharma Inc Verfahren zum inhalieren trockener pulver
US9006175B2 (en) 1999-06-29 2015-04-14 Mannkind Corporation Potentiation of glucose elimination
WO2003080149A2 (en) 2002-03-20 2003-10-02 Mannkind Corporation Inhalation apparatus
RU2216353C1 (ru) * 2002-10-16 2003-11-20 Научно-исследовательский институт вакцин и сывороток им. И.И. Мечникова РАМН Способ получения гранулированной лекарственной формы из аллергена клещей рода dermatophagoides farinae
ATE486064T1 (de) 2004-08-20 2010-11-15 Mannkind Corp Katalyse der diketopiperazinsynthese
HUE025151T2 (en) 2004-08-23 2016-01-28 Mannkind Corp Diceto-piperazine salts for drug delivery
KR101486397B1 (ko) 2005-09-14 2015-01-28 맨카인드 코포레이션 활성제에 대한 결정질 미립자 표면의 친화력의 증가를 기반으로 하는 약물 제제화의 방법
KR20080096809A (ko) 2006-02-22 2008-11-03 맨카인드 코포레이션 디케토피페라진 및 활성제를 포함하는 마이크로입자의 약학특성의 개선 방법
ES2929343T3 (es) 2008-06-13 2022-11-28 Mannkind Corp Inhalador de polvo seco accionado por aspiración para la administración de fármacos
US8485180B2 (en) * 2008-06-13 2013-07-16 Mannkind Corporation Dry powder drug delivery system
MX2010014240A (es) 2008-06-20 2011-03-25 Mankind Corp Un metodo y aparato interactivo para perfilar en tiempo real esfuerzos de inhalacion.
TWI494123B (zh) 2008-08-11 2015-08-01 Mannkind Corp 超快起作用胰島素之用途
US8314106B2 (en) 2008-12-29 2012-11-20 Mannkind Corporation Substituted diketopiperazine analogs for use as drug delivery agents
WO2010105094A1 (en) 2009-03-11 2010-09-16 Mannkind Corporation Apparatus, system and method for measuring resistance of an inhaler
MY157166A (en) 2009-06-12 2016-05-13 Mankind Corp Diketopiperazine microparticles with defined specific surface areas
WO2011056889A1 (en) 2009-11-03 2011-05-12 Mannkind Corporation An apparatus and method for simulating inhalation efforts
BR112012033060A2 (pt) 2010-06-21 2018-02-27 Mannkind Corp métodos de sistema de liberação de fármaco em pó seco
AU2012236150B2 (en) 2011-04-01 2016-03-31 Mannkind Corporation Blister package for pharmaceutical cartridges
WO2012174472A1 (en) 2011-06-17 2012-12-20 Mannkind Corporation High capacity diketopiperazine microparticles
BR112014009686A2 (pt) 2011-10-24 2018-08-07 Mannkind Corp composição analgésica inalável, pó seco e método para tratar dor
AU2013289957B2 (en) 2012-07-12 2017-02-23 Mannkind Corporation Dry powder drug delivery systems and methods
WO2014066856A1 (en) 2012-10-26 2014-05-01 Mannkind Corporation Inhalable influenza vaccine compositions and methods
KR102246914B1 (ko) 2013-03-15 2021-04-30 맨카인드 코포레이션 미세결정성 디케토피페라진 조성물 및 방법
CN114848614A (zh) 2013-07-18 2022-08-05 曼金德公司 热稳定性干粉药物组合物和方法
EP3030294B1 (en) 2013-08-05 2020-10-07 MannKind Corporation Insufflation apparatus
US10307464B2 (en) 2014-03-28 2019-06-04 Mannkind Corporation Use of ultrarapid acting insulin
US10561806B2 (en) 2014-10-02 2020-02-18 Mannkind Corporation Mouthpiece cover for an inhaler

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3148121A (en) * 1960-01-27 1964-09-08 Miles Lab Water-insoluble whole inhalant complex and method of making same
GB1055465A (en) * 1962-09-27 1967-01-18 Vantorex Ltd Allergenic aerosol compositions
GB1182779A (en) * 1966-09-17 1970-03-04 Fisons Pharmaceuticals Ltd Inhalation Device
GB1247614A (en) * 1969-06-20 1971-09-29 Miles Lab Improved therapeutic and diagnostic allergenic extract and process for preparing same
BR6915418D0 (pt) * 1969-10-13 1973-03-13 Synergistics Inc Processo de preparacao de um composto antigeno de acaros e de seu soro e sua titulacao
GB1381872A (en) * 1971-06-22 1975-01-29 Fisons Ltd Pharmaceutical compositions for inhalation
NL7316346A (enExample) * 1972-12-11 1974-06-13
US3995023A (en) * 1972-12-11 1976-11-30 Merck Patent Gesellschaft Mit Beschrankter Haftung Process for the production of allergen-containing extracts
FR2466991A1 (fr) * 1979-10-08 1981-04-17 Pasteur Institut Perfectionnement a la preparation d'allergene

Also Published As

Publication number Publication date
FR2512670B1 (fr) 1986-12-19
JPH0575726B2 (enExample) 1993-10-21
CH650925A5 (it) 1985-08-30
NO821832L (no) 1982-12-06
US4681752A (en) 1987-07-21
IT8122136A0 (it) 1981-06-04
ATE20518T1 (de) 1986-07-15
NO156275B (no) 1987-05-18
DK153920C (da) 1989-02-06
EP0067130A3 (en) 1984-01-11
IT1220979B (it) 1990-06-21
DK153920B (da) 1988-09-26
CA1207663A (en) 1986-07-15
EP0067130B1 (en) 1986-06-25
NO156275C (no) 1987-08-26
IL65875A0 (en) 1982-08-31
EP0067130A2 (en) 1982-12-15
FR2512670A1 (fr) 1983-03-18
DK239782A (da) 1982-12-05
GR76810B (enExample) 1984-09-04
IL65875A (en) 1986-09-30
JPS57212114A (en) 1982-12-27

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8328 Change in the person/name/address of the agent

Free format text: DERZEIT KEIN VERTRETER BESTELLT

8328 Change in the person/name/address of the agent

Free format text: LORENZ, W., DIPL.-ING., PAT.-ANW., 7920 HEIDENHEIM

8327 Change in the person/name/address of the patent owner

Owner name: LOFARMA S.P.A., MAILAND/MILANO, IT MELILLO, GAETAN

8328 Change in the person/name/address of the agent

Free format text: MITSCHERLICH & PARTNER, PATENT- UND RECHTSANWAELTE, 80331 MUENCHEN