DE3261007D1 - 4-(n-(hydroxybenzyl)aminomethyl)cyclohexane-1-carboxylic acids - Google Patents

4-(n-(hydroxybenzyl)aminomethyl)cyclohexane-1-carboxylic acids

Info

Publication number
DE3261007D1
DE3261007D1 DE8282306157T DE3261007T DE3261007D1 DE 3261007 D1 DE3261007 D1 DE 3261007D1 DE 8282306157 T DE8282306157 T DE 8282306157T DE 3261007 T DE3261007 T DE 3261007T DE 3261007 D1 DE3261007 D1 DE 3261007D1
Authority
DE
Germany
Prior art keywords
hydroxybenzyl
aminomethyl
cyclohexane
carboxylic acids
carboxylic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8282306157T
Other languages
English (en)
Inventor
Hitoshi Takita
Yutaka Mukaida
Sakuo Noda
Hidetoshi Kobayashi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kureha Corp
Original Assignee
Kureha Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kureha Corp filed Critical Kureha Corp
Application granted granted Critical
Publication of DE3261007D1 publication Critical patent/DE3261007D1/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/04—Formation of amino groups in compounds containing carboxyl groups
    • C07C227/06—Formation of amino groups in compounds containing carboxyl groups by addition or substitution reactions, without increasing the number of carbon atoms in the carbon skeleton of the acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/46—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino or carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/14—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof
    • C07C227/18—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof by reactions involving amino or carboxyl groups, e.g. hydrolysis of esters or amides, by formation of halides, salts or esters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/46—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino or carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C229/48—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino or carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups and carboxyl groups bound to carbon atoms of the same non-condensed ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Pulmonology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE8282306157T 1981-11-20 1982-11-18 4-(n-(hydroxybenzyl)aminomethyl)cyclohexane-1-carboxylic acids Expired DE3261007D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP56186691A JPS58109455A (ja) 1981-11-20 1981-11-20 Ｎ−ベンジルアミノ酸誘導体及びその製造法

Publications (1)

Publication Number Publication Date
DE3261007D1 true DE3261007D1 (de) 1984-11-22

Family

ID=16192941

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8282306157T Expired DE3261007D1 (de) 1981-11-20 1982-11-18 4-(n-(hydroxybenzyl)aminomethyl)cyclohexane-1-carboxylic acids

Country Status (6)

Country Link
US (1) US4464396A (de)
EP (1) EP0080334B1 (de)
JP (1) JPS58109455A (de)
KR (1) KR870001086B1 (de)
CA (1) CA1193280A (de)
DE (1) DE3261007D1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59193822A (ja) * 1983-04-15 1984-11-02 Kureha Chem Ind Co Ltd 腎炎治療剤
US4758591A (en) * 1983-12-26 1988-07-19 Kureha Kagaku Kogyo Kabushiki Kaisha Dialkanoyloxybenzylidene dialkanoate
EP2601950A1 (de) * 2011-12-06 2013-06-12 Sanofi Cycloalkancarbonsäure Derivate als CXCR3 Rezeptor Antagonisten

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3268405A (en) * 1961-05-08 1966-08-23 Mitsubishi Chem Ind 4-aminomethyl-cyclohexane-1-carboxylic acid for inhibiting the activation of plasmin
US4163060A (en) * 1974-04-08 1979-07-31 U.S. Philips Corporation Aralkylamino carboxylic acids and derivatives having spasmolytic activity
US4055580A (en) * 1975-08-22 1977-10-25 Rorer Italiana S.P.A. Derivatives of aminomethylcyclohexanecarboxylic acid
EP0021636B1 (de) * 1979-06-16 1982-12-01 Beecham Group Plc Sekundäre Amine, ihre Herstellung und Verwendung in pharmazeutischen Zusammensetzungen
DK330880A (da) * 1979-08-03 1981-02-04 Beecham Group Ltd Fremgangsmaade til fremstilling af clavulansyrederivater
US4382955A (en) * 1980-06-04 1983-05-10 Kureha Kagaku Kogyo Kabushiki Kaisha Derivative of 4-(N-(3,4-dihydroxybenzylidene) aminomethyl cyclohexane-1-carboxylic acid
JPS5759848A (en) * 1980-09-29 1982-04-10 Hisamitsu Pharmaceut Co Inc Cyclohexanecarboxylic acid derivative

Also Published As

Publication number Publication date
JPH0155267B2 (de) 1989-11-22
KR870001086B1 (ko) 1987-06-04
KR840002344A (ko) 1984-06-25
US4464396A (en) 1984-08-07
EP0080334A1 (de) 1983-06-01
JPS58109455A (ja) 1983-06-29
EP0080334B1 (de) 1984-10-17
CA1193280A (en) 1985-09-10

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Legal Events

Date Code Title Description
8328 Change in the person/name/address of the agent

Free format text: KADOR, U., DIPL.-CHEM. DR.RER.NAT., PAT.-ANW., 8000 MUENCHEN

8339 Ceased/non-payment of the annual fee