DE3200766A1 - Praeparat mit ausgezeichneter absorptionseigenschaft - Google Patents

Praeparat mit ausgezeichneter absorptionseigenschaft

Info

Publication number
DE3200766A1
DE3200766A1 DE19823200766 DE3200766A DE3200766A1 DE 3200766 A1 DE3200766 A1 DE 3200766A1 DE 19823200766 DE19823200766 DE 19823200766 DE 3200766 A DE3200766 A DE 3200766A DE 3200766 A1 DE3200766 A1 DE 3200766A1
Authority
DE
Germany
Prior art keywords
acid
water
soluble
preparation according
chelating
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
DE19823200766
Other languages
German (de)
English (en)
Inventor
Renji Aikawa
Yasuyo Miyauchi
Masataka Morishita
Yoshiaki Yamamoto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Toyo Jozo KK
Original Assignee
Toyo Jozo KK
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP56003263A external-priority patent/JPS57118509A/ja
Priority claimed from JP56032951A external-priority patent/JPS57146722A/ja
Priority claimed from JP18150881A external-priority patent/JPS57146723A/ja
Priority claimed from JP56184861A external-priority patent/JPS5885813A/ja
Application filed by Toyo Jozo KK filed Critical Toyo Jozo KK
Publication of DE3200766A1 publication Critical patent/DE3200766A1/de
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0031—Rectum, anus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
    • B01F25/80—Falling particle mixers, e.g. with repeated agitation along a vertical axis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Inorganic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Gynecology & Obstetrics (AREA)
  • Reproductive Health (AREA)
  • Urology & Nephrology (AREA)
  • Biophysics (AREA)
  • Medicinal Preparation (AREA)
DE19823200766 1981-01-14 1982-01-13 Praeparat mit ausgezeichneter absorptionseigenschaft Pending DE3200766A1 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP56003263A JPS57118509A (en) 1981-01-14 1981-01-14 Novel preparation of high absorbability
JP56032951A JPS57146722A (en) 1981-03-06 1981-03-06 Pharmaceutical preparation having improved absorption
JP18150881A JPS57146723A (en) 1981-03-06 1981-11-11 Pharmaceutical preparation having improved absorption
JP56184861A JPS5885813A (ja) 1981-11-17 1981-11-17 吸収性良好な製剤

Publications (1)

Publication Number Publication Date
DE3200766A1 true DE3200766A1 (de) 1982-09-16

Family

ID=27453826

Family Applications (2)

Application Number Title Priority Date Filing Date
DE19823200766 Pending DE3200766A1 (de) 1981-01-14 1982-01-13 Praeparat mit ausgezeichneter absorptionseigenschaft
DE19823250023 Pending DE3250023T (enrdf_load_stackoverflow) 1981-01-14 1982-01-13

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE19823250023 Pending DE3250023T (enrdf_load_stackoverflow) 1981-01-14 1982-01-13

Country Status (2)

Country Link
CA (1) CA1184492A (enrdf_load_stackoverflow)
DE (2) DE3200766A1 (enrdf_load_stackoverflow)

Cited By (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2542616A1 (fr) * 1983-03-17 1984-09-21 Unilever Nv Composition pour le traitement des muqueuses a base d'un antibiotique et d'un hydrocolloide formateur de gel
EP0193287A3 (en) * 1985-02-19 1986-10-08 Nippon Kayaku Kabushiki Kaisha Etoposide preparations
EP0273202A3 (en) * 1986-12-23 1990-06-06 Eugene J. Dr. Van Scott Additives enhancing topical actions of therapeutic agents
WO1990009780A1 (en) * 1989-02-25 1990-09-07 Danbiosyst Uk Limited Drug delivery compositions
FR2650502A1 (fr) * 1989-08-07 1991-02-08 Delagrange Laboratoires Nouvelle forme galenique orale ameliorant la biodisponibilite
EP0326151A3 (en) * 1988-01-29 1991-03-13 Sumitomo Pharmaceuticals Company, Limited Improved controlled release formulation
WO1993025239A1 (en) * 1992-06-17 1993-12-23 Advanced Magnetics Inc. Arabinogalactan derivatives and uses thereof
US5554388A (en) * 1989-02-25 1996-09-10 Danbiosyst Uk Limited Systemic drug delivery compositions comprising a polycationi substance
US5554386A (en) * 1986-07-03 1996-09-10 Advanced Magnetics, Inc. Delivery of therapeutic agents to receptors using polysaccharides
WO2002057777A3 (de) * 2001-01-20 2003-05-08 Klaus-Dieter Kunze Verfahren zur reduzierung von nebenwirkungen bei arzneimitteln
US8013017B2 (en) 2001-05-31 2011-09-06 Upsher-Smith Laboratories, Inc. Dermatological compositions and methods
DE102010015350A1 (de) 2010-04-16 2011-10-20 Michael Zimmermann Vaginalapplikator

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB761809A (en) * 1953-09-02 1956-11-21 Merck & Co Inc Solid pharmaceutical preparation containing streptomycin and/or dihydrostreptomycin
GB1061426A (en) * 1964-05-22 1967-03-15 Olin Mathieson Water-soluble penicillin composition
US4024073A (en) * 1972-01-08 1977-05-17 Toray Industries, Inc. Hydrogel and production thereof
FR2455897A1 (fr) * 1979-05-10 1980-12-05 Kyoto Pharma Ind Adjuvant du type acide gras pour favoriser l'absorption de substances pharmacologiquement actives par le rectum, composition de base pour administration rectale comprenant cet adjuvant et composition pharmaceutique comprenant cet adjuvant
EP0031561A2 (en) * 1979-12-20 1981-07-08 Merck & Co. Inc. A rectally administered suppository comprising a drug and an adjuvant

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB761809A (en) * 1953-09-02 1956-11-21 Merck & Co Inc Solid pharmaceutical preparation containing streptomycin and/or dihydrostreptomycin
GB1061426A (en) * 1964-05-22 1967-03-15 Olin Mathieson Water-soluble penicillin composition
US4024073A (en) * 1972-01-08 1977-05-17 Toray Industries, Inc. Hydrogel and production thereof
FR2455897A1 (fr) * 1979-05-10 1980-12-05 Kyoto Pharma Ind Adjuvant du type acide gras pour favoriser l'absorption de substances pharmacologiquement actives par le rectum, composition de base pour administration rectale comprenant cet adjuvant et composition pharmaceutique comprenant cet adjuvant
EP0031561A2 (en) * 1979-12-20 1981-07-08 Merck & Co. Inc. A rectally administered suppository comprising a drug and an adjuvant

Cited By (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0125759A3 (en) * 1983-03-17 1986-06-25 Unilever Plc Topical composition of antibiotics for application to the mucosa
FR2542616A1 (fr) * 1983-03-17 1984-09-21 Unilever Nv Composition pour le traitement des muqueuses a base d'un antibiotique et d'un hydrocolloide formateur de gel
EP0193287A3 (en) * 1985-02-19 1986-10-08 Nippon Kayaku Kabushiki Kaisha Etoposide preparations
US5554386A (en) * 1986-07-03 1996-09-10 Advanced Magnetics, Inc. Delivery of therapeutic agents to receptors using polysaccharides
EP0273202A3 (en) * 1986-12-23 1990-06-06 Eugene J. Dr. Van Scott Additives enhancing topical actions of therapeutic agents
EP0326151A3 (en) * 1988-01-29 1991-03-13 Sumitomo Pharmaceuticals Company, Limited Improved controlled release formulation
US5554388A (en) * 1989-02-25 1996-09-10 Danbiosyst Uk Limited Systemic drug delivery compositions comprising a polycationi substance
WO1990009780A1 (en) * 1989-02-25 1990-09-07 Danbiosyst Uk Limited Drug delivery compositions
FR2650502A1 (fr) * 1989-08-07 1991-02-08 Delagrange Laboratoires Nouvelle forme galenique orale ameliorant la biodisponibilite
WO1993025239A1 (en) * 1992-06-17 1993-12-23 Advanced Magnetics Inc. Arabinogalactan derivatives and uses thereof
WO2002057777A3 (de) * 2001-01-20 2003-05-08 Klaus-Dieter Kunze Verfahren zur reduzierung von nebenwirkungen bei arzneimitteln
US8013017B2 (en) 2001-05-31 2011-09-06 Upsher-Smith Laboratories, Inc. Dermatological compositions and methods
US9456970B2 (en) 2001-05-31 2016-10-04 Upsher-Smith Laboratories, Inc. Dermatological compositions and methods
DE102010015350A1 (de) 2010-04-16 2011-10-20 Michael Zimmermann Vaginalapplikator
EP2389940A2 (de) 2010-04-16 2011-11-30 Michael Zimmermann Vaginalapplikator mit zwei Auslassöffnungen

Also Published As

Publication number Publication date
CA1184492A (en) 1985-03-26
DE3250023T (enrdf_load_stackoverflow) 1990-03-29

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