DE3163877D1 - Membrane modified hydrogels, process for their manufacture and their use as active agent dispenser - Google Patents

Membrane modified hydrogels, process for their manufacture and their use as active agent dispenser

Info

Publication number
DE3163877D1
DE3163877D1 DE8181810300T DE3163877T DE3163877D1 DE 3163877 D1 DE3163877 D1 DE 3163877D1 DE 8181810300 T DE8181810300 T DE 8181810300T DE 3163877 T DE3163877 T DE 3163877T DE 3163877 D1 DE3163877 D1 DE 3163877D1
Authority
DE
Germany
Prior art keywords
manufacture
active agent
agent dispenser
membrane modified
modified hydrogels
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8181810300T
Other languages
English (en)
Inventor
Karl Friedrich Mueller
Sonia Jaworiw Heiber
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Application granted granted Critical
Publication of DE3163877D1 publication Critical patent/DE3163877D1/de
Expired legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L75/00—Compositions of polyureas or polyurethanes; Compositions of derivatives of such polymers
    • C08L75/04—Polyurethanes
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
    • A01N25/08—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests containing solids as carriers or diluents
    • A01N25/10—Macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L9/00—Disinfection, sterilisation or deodorisation of air
    • A61L9/015—Disinfection, sterilisation or deodorisation of air using gaseous or vaporous substances, e.g. ozone
    • A61L9/04—Disinfection, sterilisation or deodorisation of air using gaseous or vaporous substances, e.g. ozone using substances evaporated in the air without heating
    • A61L9/042—Disinfection, sterilisation or deodorisation of air using gaseous or vaporous substances, e.g. ozone using substances evaporated in the air without heating with the help of a macromolecular compound as a carrier or diluent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L9/00—Disinfection, sterilisation or deodorisation of air
    • A61L9/015—Disinfection, sterilisation or deodorisation of air using gaseous or vaporous substances, e.g. ozone
    • A61L9/04—Disinfection, sterilisation or deodorisation of air using gaseous or vaporous substances, e.g. ozone using substances evaporated in the air without heating
    • A61L9/12—Apparatus, e.g. holders, therefor
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D69/00—Semi-permeable membranes for separation processes or apparatus characterised by their form, structure or properties; Manufacturing processes specially adapted therefor
    • B01D69/14—Dynamic membranes
    • B01D69/141—Heterogeneous membranes, e.g. containing dispersed material; Mixed matrix membranes
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00—Polymeric products of isocyanates or isothiocyanates
    • C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/08—Processes
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J3/00—Processes of treating or compounding macromolecular substances
    • C08J3/005—Processes for mixing polymers
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L101/00—Compositions of unspecified macromolecular compounds
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L75/00—Compositions of polyureas or polyurethanes; Compositions of derivatives of such polymers
    • C08L75/04—Polyurethanes
    • C08L75/14—Polyurethanes having carbon-to-carbon unsaturated bonds
    • C08L75/16—Polyurethanes having carbon-to-carbon unsaturated bonds having terminal carbon-to-carbon unsaturated bonds
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
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    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
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    • C08L2205/04—Polymer mixtures characterised by other features containing interpenetrating networks
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    • Y10T428/1352—Polymer or resin containing [i.e., natural or synthetic]
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    • Y10T428/249995—Constituent is in liquid form
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Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pest Control & Pesticides (AREA)
  • Wood Science & Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Plant Pathology (AREA)
  • Toxicology (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • Agronomy & Crop Science (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
  • Cosmetics (AREA)
  • Materials For Medical Uses (AREA)
DE8181810300T 1980-07-28 1981-07-22 Membrane modified hydrogels, process for their manufacture and their use as active agent dispenser Expired DE3163877D1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/172,908 US4423099A (en) 1980-07-28 1980-07-28 Membrane modified hydrogels

Publications (1)

Publication Number Publication Date
DE3163877D1 true DE3163877D1 (en) 1984-07-05

Family

ID=22629698

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8181810300T Expired DE3163877D1 (en) 1980-07-28 1981-07-22 Membrane modified hydrogels, process for their manufacture and their use as active agent dispenser

Country Status (4)

Country Link
US (1) US4423099A (de)
EP (1) EP0046136B1 (de)
JP (1) JPS5755967A (de)
DE (1) DE3163877D1 (de)

Families Citing this family (107)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2513243B1 (de) * 1981-09-24 1983-11-18 Commissariat Energie Atomique
JPS58174310A (ja) * 1982-04-06 1983-10-13 Wakamoto Pharmaceut Co Ltd 抗炎症点眼剤
DE3214667C2 (de) * 1982-04-21 1985-07-18 Akzo Gmbh, 5600 Wuppertal Zusammengesetzter Körper für die Langzeitabgabe von Wirkstoffen
US4631188A (en) * 1983-08-31 1986-12-23 S.K.Y. Polymers, Ltd. (Kingston Technologies) Injectable physiologically-acceptable polymeric composition
US4693887A (en) * 1983-09-15 1987-09-15 The Kendall Company Microphase separated hydrogels for controlled release of bioactive materials
US5000957A (en) * 1984-03-19 1991-03-19 Alza Corporation Dispenser comprising hydrophilic osmopolymer
DE3566954D1 (en) * 1984-03-20 1989-02-02 Akzo Gmbh Cellulose dialysis membrane with improved biocompatibility
US4911691A (en) * 1984-09-21 1990-03-27 Menlo Care, Inc. Assembly for adminstering IV solution
US4883699A (en) * 1984-09-21 1989-11-28 Menlo Care, Inc. Polymeric article having high tensile energy to break when hydrated
US4546123A (en) * 1984-12-28 1985-10-08 Alcon Laboratories, Inc. Polymer hydrogels adapted for use as soft contact lenses, and method of preparing same
JPS62502123A (ja) * 1985-03-06 1987-08-20 メムテック・リミテッド 孔径分布の変更方法
US4575539A (en) * 1985-06-03 1986-03-11 E. R. Squibb & Sons, Inc. Drug delivery systems including novel interpenetrating polymer networks and method
US4717568A (en) * 1985-08-09 1988-01-05 Alza Corporation Laminar arrangement for increasing delivery of beneficial agent from dispenser
US4766036A (en) * 1985-09-16 1988-08-23 The Dow Chemical Company Process for producing porous fibers from orientable olefin polymers having cation-containing, pendent reactive side-groups and the resultant product
US5145675A (en) * 1986-03-31 1992-09-08 Advanced Polymer Systems, Inc. Two step method for preparation of controlled release formulations
US4668564A (en) * 1985-12-26 1987-05-26 Spenco Medical Corporation Hydrogel materials for hot and cold therapy and method for forming same
US4959217A (en) * 1986-05-22 1990-09-25 Syntex (U.S.A.) Inc. Delayed/sustained release of macromolecules
US4983400A (en) * 1986-06-16 1991-01-08 Merck & Co., Inc. Controlled release combination of carbidopa/levodopa
KR890003548B1 (ko) * 1986-08-29 1989-09-23 한국과학기술원 다성분계 고분자 분리막의 제조방법
US4908236A (en) * 1986-12-04 1990-03-13 Millipore Corporation Transparent porous membrane having hydrophilic surface and process
US4879316A (en) * 1987-02-26 1989-11-07 The University Of Tennessee Research Corporation Interpenetrating polymer network ion exchange membranes and method for preparing same
US4809912A (en) * 1987-03-27 1989-03-07 Delaire, Inc. Membrane-gel diffusion device
US4923934A (en) * 1987-05-29 1990-05-08 Werner Todd A Interpenetrating polymer network of blocked urethane prepolymer, polyol, epoxy resin and anhydride
US4789547A (en) * 1987-06-17 1988-12-06 Warner-Lambert Company Transdermal matrix system
US4891223A (en) * 1987-09-03 1990-01-02 Air Products And Chemicals, Inc. Controlled release delivery coating formulation for bioactive substances
US4837054A (en) * 1987-10-14 1989-06-06 Exxon Research And Engineering Company Thin film composite membrane prepared by deposition from a solution
US4921611A (en) * 1987-10-14 1990-05-01 Schucker Robert C Thin film composite membrane prepared by deposition from a solution
US4910015A (en) * 1987-10-19 1990-03-20 Massachusetts Institute Of Technology Surface-active polysiloxanes and drug releasing materials thereof
US4943618A (en) * 1987-12-18 1990-07-24 Kingston Technologies Limited Partnership Method for preparing polyacrylonitrile copolymers by heterogeneous reaction of polyacrylonitrile aquagel
US4939007A (en) * 1988-03-07 1990-07-03 Becton, Dickinson And Company Article having a hemocompatible surface
US4842761A (en) * 1988-03-23 1989-06-27 International Flavors & Fragrances, Inc. Compositions and methods for controlled release of fragrance-bearing substances
US5045354A (en) * 1989-12-19 1991-09-03 Exxon Research & Engineering Company Production of supported thin film membranes
NL9001274A (nl) * 1990-06-06 1992-01-02 X Flow Bv Semi-permeabel composietmembraan, alsmede werkwijze voor het vervaardigen ervan.
US5514379A (en) * 1992-08-07 1996-05-07 The General Hospital Corporation Hydrogel compositions and methods of use
US5480950A (en) * 1992-09-28 1996-01-02 Kabi Pharmacia Ophthalmics, Inc. High refractive index hydrogels and uses thereof
US6440457B1 (en) * 1993-05-27 2002-08-27 Alza Corporation Method of administering antidepressant dosage form
EP0773975A4 (de) * 1994-08-04 1998-06-10 Gordon George Wallace Leitfähige elektroaktive biomaterialien
US5830967A (en) * 1994-10-24 1998-11-03 Amcol International Corporation Process for producing an oil and water adsorbent polymer capable of entrapping solid particles and liquids and the product thereof
US6107429A (en) * 1994-10-24 2000-08-22 Amcol International Corporation Process for producing an oil and water adsorbent polymer capable of entrapping solid particles and liquids and the product thereof
US5837790A (en) 1994-10-24 1998-11-17 Amcol International Corporation Precipitation polymerization process for producing an oil adsorbent polymer capable of entrapping solid particles and liquids and the product thereof
US5712358A (en) * 1995-06-07 1998-01-27 Amcol International Corporation Process for producing an oil sorbent copolymer and the product thereof
US5855615A (en) * 1996-06-07 1999-01-05 Menlo Care, Inc. Controller expansion sphincter augmentation media
US5813411A (en) * 1996-08-20 1998-09-29 Menlo Care, Inc. Method of deforming tissue with a swollen hydrogel
US7049346B1 (en) * 1996-08-20 2006-05-23 Menlo Care Div Of Ethicon, Inc. Swollen hydrogel for sphincter augmentation
DE19654468C1 (de) * 1996-12-27 1998-01-22 Lohmann Therapie Syst Lts Extrem flexibles, dermal oder transdermal wirkendes Pflaster und Verfahren zu seiner Herstellung
US5843060A (en) * 1997-01-02 1998-12-01 Xomed Surgical Products, Inc. Non-adherent nasal, sinus and otic packing and method for processing sponge materials in fabrication of packings
US6265444B1 (en) * 1997-05-23 2001-07-24 Insite Vision Incorporated Ophthalmic composition
US6943204B2 (en) * 1997-06-02 2005-09-13 Advanced Medical Optics Uppsala Ab Process for the modification of elastomers with surface interpenetrating polymer networks and elastomers formed therefrom
US6011082A (en) * 1997-06-02 2000-01-04 Pharmacia & Upjohn Ab Process for the modification of elastomers with surface interpreting polymer networks and elastomers formed therefrom
US6146771A (en) * 1997-07-01 2000-11-14 Terumo Cardiovascular Systems Corporation Process for modifying surfaces using the reaction product of a water-insoluble polymer and a polyalkylene imine
GB9720506D0 (en) 1997-09-27 1997-11-26 Scimat Ltd Gel materials
US6331578B1 (en) 1998-11-18 2001-12-18 Josephine Turner Process for preparing interpenetrating polymer networks of controlled morphology
US6843071B1 (en) 1999-02-26 2005-01-18 Tempra Technology Inc. Preparation of refrigerant materials
EP1230855B1 (de) * 1999-11-19 2008-10-01 Nof Corporation Zubereitung vom wässrigen dispersionstyp mit verzögerter freigabe und verfahren zu ihrer herstellung
CA2394077A1 (en) * 1999-12-16 2001-06-21 Trident Technologies, Llc System and method for extended delivery of a therapeutic agent with its receptor loading dose
AU2001257359A1 (en) 2000-04-27 2001-11-07 Verion Inc. Zero order release and temperature-controlled microcapsules and process for the preparation thereof
US6423332B1 (en) 2000-05-26 2002-07-23 Ethicon, Inc. Method and composition for deforming soft tissues
GB0027357D0 (en) 2000-11-09 2000-12-27 Bradford Particle Design Plc Particle formation methods and their products
US6648911B1 (en) 2000-11-20 2003-11-18 Avantec Vascular Corporation Method and device for the treatment of vulnerable tissue site
GB0208742D0 (en) 2002-04-17 2002-05-29 Bradford Particle Design Ltd Particulate materials
US7582284B2 (en) 2002-04-17 2009-09-01 Nektar Therapeutics Particulate materials
GB0216562D0 (en) 2002-04-25 2002-08-28 Bradford Particle Design Ltd Particulate materials
US9339459B2 (en) 2003-04-24 2016-05-17 Nektar Therapeutics Particulate materials
US20040056371A1 (en) * 2002-09-25 2004-03-25 Medennium, Inc. Method of manufacturing ophthalmic lenses made from hydrophobic acrylic polymers
WO2004064757A2 (en) * 2003-01-23 2004-08-05 Shire Laboratories, Inc. Absorption enhancing agents
JP4773348B2 (ja) 2003-07-12 2011-09-14 アクセラー８ テクノロジー コーポレイション 高感度かつ迅速なバイオ検出法
US20120077206A1 (en) 2003-07-12 2012-03-29 Accelr8 Technology Corporation Rapid Microbial Detection and Antimicrobial Susceptibility Testing
JP4842567B2 (ja) * 2004-06-21 2011-12-21 日信化学工業株式会社 マイクロカプセルエマルジョン及びその製造方法
US20060045854A1 (en) 2004-08-27 2006-03-02 Lynette Zaidel Oral care composition with cross-linked polymer peroxide
US20090088846A1 (en) 2007-04-17 2009-04-02 David Myung Hydrogel arthroplasty device
US20060147394A1 (en) * 2004-12-30 2006-07-06 Ramachandra Shastry Tooth whitening composition containing cross-linked polymer-peroxides
US20070071695A1 (en) 2005-09-27 2007-03-29 Colgate-Palmolive Company Single phase whitening dentifrice
HUE032364T2 (en) 2006-02-01 2017-09-28 Hollister Inc Methods for Applying a Hydrophilic Coating to a Substrate and Substrates with Hydrophilic Coating
MY144201A (en) * 2006-05-01 2011-08-15 Colgate Palmolive Co Oral care composition with silicone composite
WO2008052568A1 (en) * 2006-11-03 2008-05-08 Nanon A/S A method of producing an article comprising an interpenetrating polymer network (ipn) and an article comprising an ipn
EP2425820B1 (de) 2007-02-11 2015-04-08 MAP Pharmaceuticals Inc Verfahren zur therapeutischen Verabreichung von DHE zur schnellen Linderung von Migräne bei gleichzeitiger Minimierung von Nebenwirkungsprofilen
KR100838809B1 (ko) * 2007-05-03 2008-06-17 성균관대학교산학협력단 겔강도가 우수한 온도 및 피에치 민감성 블록 공중합체 및이의 제조방법과 이를 이용한 약물전달체
PL2178931T3 (pl) * 2007-07-19 2012-08-31 Novartis Ag Materiały i soczewki o wysokim przepływie jonu i metabolitu
CN101801350A (zh) 2007-08-13 2010-08-11 阿巴斯迪特宁医药有限公司 抗滥用药物、使用方法和制备方法
EP2297217B1 (de) * 2008-07-07 2021-10-20 Hyalex Orthopaedics, Inc. Aus hydrophoben polymeren abgeleitete netzwerke aus interpenetrierenden hydrophilen polymeren
US20120209396A1 (en) 2008-07-07 2012-08-16 David Myung Orthopedic implants having gradient polymer alloys
KR20110040969A (ko) * 2008-08-05 2011-04-20 바이오미메디카, 인코포레이티드 폴리우레탄-그라프트된 하이드로겔
US20110223297A1 (en) * 2010-03-12 2011-09-15 Pepsico., Inc. Anti-Caking Agent for Flavored Products
US9993793B2 (en) 2010-04-28 2018-06-12 The Procter & Gamble Company Delivery particles
US9186642B2 (en) 2010-04-28 2015-11-17 The Procter & Gamble Company Delivery particle
US20130217829A1 (en) 2010-08-27 2013-08-22 David Myung "hydrophobic and hydrophilic interpenetrating polymer networks derived from hydrophobic polymers and methods of preparing the same"
US20130251961A1 (en) * 2010-12-16 2013-09-26 3M Innovative Properties Company Interpenetrated Polymer Layer
MX350838B (es) 2011-02-11 2017-09-18 Grain Proc Corporation * Composicion de sal.
US10254204B2 (en) 2011-03-07 2019-04-09 Accelerate Diagnostics, Inc. Membrane-assisted purification
ES2551922T3 (es) 2011-03-07 2015-11-24 Accelerate Diagnostics, Inc. Sistemas rápidos de purificación celular
MX2013010980A (es) 2011-04-07 2013-10-30 Procter & Gamble Composiciones de limpieza personal con deposito mejorado de microcapsulas de poliacrilato.
CN103458871B (zh) 2011-04-07 2015-05-13 宝洁公司 具有增强的聚丙烯酸酯微胶囊的沉积的调理剂组合物
CN103458858B (zh) 2011-04-07 2016-04-27 宝洁公司 具有增强的聚丙烯酸酯微胶囊的沉积的洗发剂组合物
CA2885996A1 (en) 2011-10-03 2013-04-11 Biomimedica, Inc. Polymeric adhesive for anchoring compliant materials to another surface
CA2856512A1 (en) 2011-11-21 2013-05-30 Biomimedica, Inc. Systems, devices, and methods for anchoring orthopaedic implants to bone
US8952105B2 (en) * 2012-05-23 2015-02-10 Baker Hughes Incorporated Variable TG article, method of making, and use of same
CA2907428A1 (en) 2013-03-15 2014-09-18 Inspirion Delivery Technologies, Llc Abuse deterrent compositions and methods of use
US9677109B2 (en) 2013-03-15 2017-06-13 Accelerate Diagnostics, Inc. Rapid determination of microbial growth and antimicrobial susceptibility
US9512279B2 (en) * 2013-12-18 2016-12-06 Universite Cegy-Pontoise Interpenetrating polymer network
US10729685B2 (en) 2014-09-15 2020-08-04 Ohemo Life Sciences Inc. Orally administrable compositions and methods of deterring abuse by intranasal administration
US10253355B2 (en) 2015-03-30 2019-04-09 Accelerate Diagnostics, Inc. Instrument and system for rapid microorganism identification and antimicrobial agent susceptibility testing
AU2016243656A1 (en) 2015-03-30 2017-11-09 Accelerate Diagnostics, Inc. Instrument and system for rapid microorganism identification and antimicrobial agent susceptibility testing
US9636641B2 (en) * 2015-03-31 2017-05-02 Pall Corporation Hydrophilically modified fluorinated membrane (I)
US11077228B2 (en) 2015-08-10 2021-08-03 Hyalex Orthopaedics, Inc. Interpenetrating polymer networks
BR112018010516B1 (pt) 2015-12-02 2021-01-05 Colgate-Palmolive Company gel de clareamento dental oralmente aceitável
EP3219381A1 (de) * 2016-03-16 2017-09-20 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Poröse dünnschichtmembran, verfahren zu ihrer herstellung sowie verwendungsmöglichkeiten
US10869950B2 (en) 2018-07-17 2020-12-22 Hyalex Orthopaedics, Inc. Ionic polymer compositions

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3496251A (en) * 1964-01-24 1970-02-17 Showa Denko Kk Chlorinated polyethylene graft copolymer and blends containing same
US3885078A (en) * 1968-03-06 1975-05-20 Ceskoslovenska Akademie Ved Hydrogel laminates and method of manufacturing thereof
GB1246179A (en) * 1968-03-06 1971-09-15 Ceskoslovenska Akademie Ved Hydrogel laminates and method of manufacture
US3578545A (en) * 1968-08-19 1971-05-11 Carson Saeks Inc Flexible odor-liberating laminate
US3764363A (en) * 1969-07-22 1973-10-09 Inmont Corp Surface treatment of microporous surface of sheet material and product produced
US4302553A (en) * 1970-10-30 1981-11-24 Harry L. Frisch Interpenetrating polymeric networks
US3948254A (en) * 1971-11-08 1976-04-06 Alza Corporation Novel drug delivery device
US4181694A (en) * 1972-04-28 1980-01-01 Asahi Kasei Kogyo Kabushiki Kaisha Method for producing hollow fibers of acrylonitrile polymers for ultrafilter
US4204018A (en) * 1972-05-19 1980-05-20 Bernstein Bruce S Activated polymer materials and process for making same
US3810814A (en) * 1972-12-18 1974-05-14 Gen Electric Asymmetric polymer membranes of reduced elastic modulus
US3940469A (en) * 1973-11-26 1976-02-24 Standard Oil Company Process for forming hollow fibers
GB1461445A (en) * 1974-02-20 1977-01-13 Shell Int Research Slow-release composition
US3954666A (en) * 1974-07-11 1976-05-04 E. I. Du Pont De Nemours And Company Semipermeable microcapsules containing heterogeneous catalysts and ferromagnetic materials
US4051159A (en) * 1976-01-12 1977-09-27 Avon Products, Inc. Transparent fragrance releasing composition and method of making same
US4164560A (en) * 1977-01-05 1979-08-14 Folkman Moses J Systems for the controlled release of macromolecules
US4265959A (en) * 1977-01-12 1981-05-05 Sumitomo Chemical Company, Limited Process for producing semipermeable membranes
US4154818A (en) * 1977-06-09 1979-05-15 Katayama Chemical Works Co., Ltd. Gel product for destroying harmful marine organisms and method of applying the same
US4224427A (en) * 1978-06-01 1980-09-23 Ciba-Geigy Corporation Process for preparing hydrogels as spherical beads of large size
US4274965A (en) * 1978-06-06 1981-06-23 Monsanto Company Lactam terpolymer membranes
DE2935097A1 (de) * 1978-09-07 1980-03-20 Kuraray Co Aethylen/vinylalkohol-copolymermembran
GB2042888B (en) * 1979-03-05 1983-09-28 Teijin Ltd Preparation for administration to the mucosa of the oral or nasal cavity
US4245420A (en) * 1979-03-13 1981-01-20 Carr William E S Artificial bait for aquatic species

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EP0046136A2 (de) 1982-02-17
EP0046136A3 (en) 1982-05-26

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