DE3070508D1 - Ubidecarenone composition enhancing the absorption - Google Patents
Ubidecarenone composition enhancing the absorptionInfo
- Publication number
- DE3070508D1 DE3070508D1 DE8080104371T DE3070508T DE3070508D1 DE 3070508 D1 DE3070508 D1 DE 3070508D1 DE 8080104371 T DE8080104371 T DE 8080104371T DE 3070508 T DE3070508 T DE 3070508T DE 3070508 D1 DE3070508 D1 DE 3070508D1
- Authority
- DE
- Germany
- Prior art keywords
- absorption
- composition enhancing
- ubidecarenone
- ubidecarenone composition
- enhancing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- ACTIUHUUMQJHFO-UHFFFAOYSA-N Coenzym Q10 Natural products COC1=C(OC)C(=O)C(CC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)C)=C(C)C1=O ACTIUHUUMQJHFO-UHFFFAOYSA-N 0.000 title 1
- 238000010521 absorption reaction Methods 0.000 title 1
- ACTIUHUUMQJHFO-UPTCCGCDSA-N coenzyme Q10 Chemical compound COC1=C(OC)C(=O)C(C\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CCC=C(C)C)=C(C)C1=O ACTIUHUUMQJHFO-UPTCCGCDSA-N 0.000 title 1
- 235000017471 coenzyme Q10 Nutrition 0.000 title 1
- 230000002708 enhancing effect Effects 0.000 title 1
- 229960004747 ubidecarenone Drugs 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/12—Ketones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Emergency Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP9363679A JPS5618914A (en) | 1979-07-25 | 1979-07-25 | Ubidecarenone composition having good absorbability |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE3070508D1 true DE3070508D1 (en) | 1985-05-23 |
Family
ID=14087821
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE8080104371T Expired DE3070508D1 (en) | 1979-07-25 | 1980-07-24 | Ubidecarenone composition enhancing the absorption |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US4325942A (enExample) |
| EP (1) | EP0023349B1 (enExample) |
| JP (1) | JPS5618914A (enExample) |
| CA (1) | CA1159767A (enExample) |
| DE (1) | DE3070508D1 (enExample) |
| ES (1) | ES8106408A1 (enExample) |
| PH (1) | PH16762A (enExample) |
Families Citing this family (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS58113127A (ja) * | 1981-12-28 | 1983-07-05 | Ajinomoto Co Inc | ユビデカレノン含有水性液 |
| IT1157269B (it) * | 1982-03-19 | 1987-02-11 | Seuref Ag | Nuove formulazioni farmaceutiche contenenti il coenzima q10 adatte per la somministrazione topica |
| JPS5913710A (ja) * | 1982-07-15 | 1984-01-24 | Shiseido Co Ltd | 養毛料 |
| EP0104043A3 (en) * | 1982-09-20 | 1984-06-06 | Ajinomoto Co., Inc. | Foodstuffs and pharmaceuticals |
| IT1191608B (it) * | 1985-02-01 | 1988-03-23 | Zambon Spa | Composizione farmaceutica e forme farmaceutiche che la contengono |
| JPS61221131A (ja) * | 1985-03-28 | 1986-10-01 | Eisai Co Ltd | 吸収促進したユビデカレノン含有組成物 |
| IE59067B1 (en) * | 1985-04-02 | 1993-12-15 | Yesair David W | Composition for delivery of orally administered drugs and other substances |
| US4874795A (en) * | 1985-04-02 | 1989-10-17 | Yesair David W | Composition for delivery of orally administered drugs and other substances |
| US4824669A (en) * | 1985-04-11 | 1989-04-25 | Board Of Regents, The University Of Texas System | Formulations of coenzyme Q10 for intravenous use |
| JPH0629180B2 (ja) * | 1986-06-16 | 1994-04-20 | エーザイ株式会社 | 吸収性の改良されたメナテトレノン含有組成物 |
| JPH01501153A (ja) * | 1986-10-23 | 1989-04-20 | アルバル・エッセ・ピ・ア | ユビデカレノン類を含有する化粧品 |
| JPS63188623A (ja) * | 1987-01-31 | 1988-08-04 | Taisho Pharmaceut Co Ltd | 吸収改善ユビデカレノン製剤 |
| US5641504A (en) * | 1988-06-09 | 1997-06-24 | Alza Corporation | Skin permeation enhancer compositions using glycerol monolinoleate |
| US5189066A (en) * | 1989-11-22 | 1993-02-23 | The Procter & Gamble Company | Pharmaceutical compositions of tebufelone |
| CA2038744C (en) * | 1990-03-23 | 2002-01-08 | Yoshitomi Pharmaceutical Industries Ltd. | Pharmaceutical composition containing slightly water-soluble drug |
| US5891466A (en) * | 1990-08-13 | 1999-04-06 | Yesair; David W. | Mixed Liped-Bicarbonate colloidal particles for delivering drugs or calories |
| EP0543943B1 (en) * | 1990-08-13 | 1995-04-26 | YESAIR, David W. | Mixed lipid-bicarbonate colloidal particles for delivering drugs or calories |
| US5571517A (en) * | 1990-08-13 | 1996-11-05 | Yesair; David W. | Mixed lipid-bicarbonate colloidal particles for delivering drugs or calories |
| PT100502A (pt) * | 1991-05-20 | 1993-08-31 | Alza Corp | Composicoes farmaceuticas para aumentar a capacidade de permeacao na pele utilizando monolinoleato de glicerol |
| US5281420A (en) * | 1992-05-19 | 1994-01-25 | The Procter & Gamble Company | Solid dispersion compositions of tebufelone |
| JP3106820B2 (ja) * | 1993-12-08 | 2000-11-06 | アールティーエー・アソシエーツ有限会社 | 畜肉、魚肉およびこれらの加工品の鮮度保持剤並びに生産性改善剤 |
| US5447729A (en) * | 1994-04-07 | 1995-09-05 | Pharmavene, Inc. | Multilamellar drug delivery systems |
| AU728695B2 (en) * | 1997-07-29 | 2001-01-18 | Boehringer Ingelheim International Gmbh | Self-emulsifying formulation for lipophilic compounds |
| IT1304406B1 (it) * | 1998-10-21 | 2001-03-19 | Danital Italia S R L | Preparazione per la veicolazione di principi attivi basata su acidigrassi polinsaturi del gruppo omega 3. |
| US7179483B2 (en) | 2000-04-26 | 2007-02-20 | Watson Pharmaceuticals, Inc. | Compositions and methods for transdermal oxybutynin therapy |
| DE10133305B4 (de) | 2001-07-12 | 2004-06-03 | Aquanova German Solubilisate Technologies (Agt) Gmbh | Ubichinon Konzentrat |
| JP2003055204A (ja) * | 2001-08-21 | 2003-02-26 | Sansho Iyaku Kk | ユビデカレノン組成物及び同組成物を内容物とするカプセル |
| KR100533458B1 (ko) * | 2002-07-20 | 2005-12-07 | 대화제약 주식회사 | 파클리탁셀의 가용화용 조성물 및 그의 제조 방법 |
| WO2004064543A1 (ja) * | 2003-01-17 | 2004-08-05 | Taiyo Kagaku Co., Ltd. | コエンザイムq10含有組成物 |
| JP4567945B2 (ja) * | 2003-01-17 | 2010-10-27 | 太陽化学株式会社 | ユビデカレノン製剤 |
| US20050260752A1 (en) * | 2003-04-01 | 2005-11-24 | Wilding Martin G | Culture medium containing enhancers of oxidative phosphorylation |
| JP5258144B2 (ja) * | 2004-12-21 | 2013-08-07 | 株式会社分子生理化学研究所 | 吸収性の改善された固形状のコエンザイムq10経口製剤の製造方法 |
| US8491888B2 (en) * | 2006-05-05 | 2013-07-23 | Softgel Formulators, Inc. | Highly absorbable coenzyme Q10 composition and method of producing same |
| JP5181497B2 (ja) * | 2007-03-05 | 2013-04-10 | 大正製薬株式会社 | ユビデカレノン含有固形製剤用組成物 |
| PL2544663T3 (pl) | 2010-03-12 | 2018-09-28 | Berg Llc | Dożylne formulacje koenzymu Q10 (CoQ10) i sposoby ich zastosowania |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3317381A (en) * | 1965-10-04 | 1967-05-02 | Takeda Chemical Industries Ltd | Method for treating peptic ulcer |
| US3426125A (en) * | 1965-04-07 | 1969-02-04 | Yukio Shigeta | Method of treating diabetes mellitus |
| US3534137A (en) * | 1965-09-30 | 1970-10-13 | Takeda Chemical Industries Ltd | Method of systemic therapy for severe early destructive periodontal disease |
| US3452144A (en) * | 1966-03-26 | 1969-06-24 | Takeda Chemical Industries Ltd | Method for treatment of congestive heart failure with coenzyme qn |
| US3808330A (en) * | 1972-07-13 | 1974-04-30 | Eisai Co Ltd | Method for treatment of hypertensive disease |
| DE2631282A1 (de) * | 1976-07-12 | 1978-01-19 | Kali Chemie Pharma Gmbh | Verfahren zur erhoehung der loeslichkeit und des dispersitaetsgrades von schwerloeslichen arzneistoffen zum zwecke deren applikation in gelatinekapseln |
| DE2700501A1 (de) * | 1977-01-07 | 1978-07-20 | Kali Chemie Pharma Gmbh | Verfahren zur herstellung fester und fluessiger loesungen von arzneistoffen zur oralen applikation |
| DE2700371A1 (de) * | 1977-01-07 | 1978-07-13 | Kali Chemie Pharma Gmbh | Verfahren zur herstellung fester und fluessiger loesungen von arzneistoffen zur oralen applikation |
| DE2700433A1 (de) * | 1977-01-07 | 1978-07-20 | Kali Chemie Pharma Gmbh | Arzneimittelzubereitungen mit verbesserten resorptionseigenschaften |
-
1979
- 1979-07-25 JP JP9363679A patent/JPS5618914A/ja active Granted
-
1980
- 1980-07-15 US US06/169,194 patent/US4325942A/en not_active Expired - Lifetime
- 1980-07-24 DE DE8080104371T patent/DE3070508D1/de not_active Expired
- 1980-07-24 ES ES493679A patent/ES8106408A1/es not_active Expired
- 1980-07-24 CA CA000356975A patent/CA1159767A/en not_active Expired
- 1980-07-24 EP EP80104371A patent/EP0023349B1/en not_active Expired
- 1980-07-25 PH PH24335A patent/PH16762A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JPS5618914A (en) | 1981-02-23 |
| US4325942A (en) | 1982-04-20 |
| EP0023349A2 (en) | 1981-02-04 |
| CA1159767A (en) | 1984-01-03 |
| JPS6410494B2 (enExample) | 1989-02-22 |
| EP0023349B1 (en) | 1985-04-17 |
| ES493679A0 (es) | 1981-07-01 |
| EP0023349A3 (en) | 1982-03-10 |
| PH16762A (en) | 1984-02-15 |
| ES8106408A1 (es) | 1981-07-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8339 | Ceased/non-payment of the annual fee |