DE3064485D1 - Anthracycline glycosides, process for their preparation and therapeutical composition containing them - Google Patents

Anthracycline glycosides, process for their preparation and therapeutical composition containing them

Info

Publication number
DE3064485D1
DE3064485D1 DE8080103743T DE3064485T DE3064485D1 DE 3064485 D1 DE3064485 D1 DE 3064485D1 DE 8080103743 T DE8080103743 T DE 8080103743T DE 3064485 T DE3064485 T DE 3064485T DE 3064485 D1 DE3064485 D1 DE 3064485D1
Authority
DE
Germany
Prior art keywords
composition containing
compounds
hydrogen atom
preparation
therapeutical composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8080103743T
Other languages
German (de)
English (en)
Inventor
Giuseppe Cassinelli
Salvatore Forenza
Maria Clara Ripamonti
Daniela Ruggieri
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Italia SRL
Original Assignee
Farmitalia Carlo Erba SRL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Farmitalia Carlo Erba SRL filed Critical Farmitalia Carlo Erba SRL
Application granted granted Critical
Publication of DE3064485D1 publication Critical patent/DE3064485D1/de
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20Carbocyclic rings
    • C07H15/24Condensed ring systems having three or more rings
    • C07H15/252Naphthacene radicals, e.g. daunomycins, adriamycins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DE8080103743T 1979-07-04 1980-07-01 Anthracycline glycosides, process for their preparation and therapeutical composition containing them Expired DE3064485D1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB7923225 1979-07-04

Publications (1)

Publication Number Publication Date
DE3064485D1 true DE3064485D1 (en) 1983-09-08

Family

ID=10506282

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8080103743T Expired DE3064485D1 (en) 1979-07-04 1980-07-01 Anthracycline glycosides, process for their preparation and therapeutical composition containing them

Country Status (9)

Country Link
US (1) US4322412A (it)
EP (1) EP0022515B1 (it)
JP (1) JPS5610200A (it)
AT (1) ATE4387T1 (it)
CA (1) CA1154012A (it)
DE (1) DE3064485D1 (it)
DK (1) DK152053C (it)
IT (1) IT1131887B (it)
SU (1) SU1017173A3 (it)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS56156300A (en) * 1980-04-26 1981-12-02 Microbial Chem Res Found Novel preparative method of anthracyclin derivative
NL8300150A (nl) * 1982-01-26 1983-08-16 Erba Farmitalia Daunorubicine en doxorubicine-analoga, hun bereiding en toepassing.
GB8708927D0 (en) * 1987-04-14 1987-05-20 Erba Farmitalia Chiral synthesis of anthracyclines
US5177091A (en) * 1990-12-06 1993-01-05 Ciba-Geigy Corporation Use of carbazones as novel active ingredients in medicaments
AU658175B2 (en) * 1991-04-12 1995-04-06 Novartis Ag Use of 2-iminothiazolidin-4-one derivatives as novel pharmaceutical active ingredients
PL380561A1 (pl) * 2006-09-05 2008-03-17 Szeja Wiesław Prochem Szeja Sposób otrzymywania pochodnych antracyklin
US8357785B2 (en) * 2008-01-08 2013-01-22 Solux Corporation Method of aralkylation of 4′-hydroxyl group of anthracylins
CN104151376B (zh) * 2014-06-23 2017-02-08 天津药物研究院新药评价有限公司 一种抗肿瘤药物及其合成方法和用途

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4039663A (en) * 1975-03-19 1977-08-02 Societa' Farmaceutici Italia S.P.A. Daunomycins, process for their uses and intermediates
GB1550879A (en) * 1976-12-22 1979-08-22 Farmaceutici Italia Antitumour glycosides
GB1573037A (en) * 1977-05-05 1980-08-13 Farmaceutici Italia Anthracyclines
BE864336A (fr) * 1977-05-05 1978-06-16 Farmaceutici Italia Nouveaux derives d'anthracyclines
NL7900869A (nl) * 1978-02-09 1979-08-13 Erba Farmitalia Anthracyclinenantibiotica.
BE883759A (fr) * 1979-06-16 1980-10-01 Erba Farmitalia Glycosides d'anthracycline

Also Published As

Publication number Publication date
IT1131887B (it) 1986-06-25
JPS6328076B2 (it) 1988-06-07
US4322412A (en) 1982-03-30
EP0022515A1 (en) 1981-01-21
DK152053C (da) 1988-08-29
SU1017173A3 (ru) 1983-05-07
DK152053B (da) 1988-01-25
ATE4387T1 (de) 1983-08-15
EP0022515B1 (en) 1983-08-03
JPS5610200A (en) 1981-02-02
DK287980A (da) 1981-01-05
CA1154012A (en) 1983-09-20
IT8023190A0 (it) 1980-07-02

Similar Documents

Publication Publication Date Title
EP0163599A3 (en) Pyrimidopyrimidine derivatives, processes for producing them, pharmaceutical compositions containing them and their use as anti-allergic agents
NZ227877A (en) Anthracycline glycosides and pharmaceutical compositions; process of preparation
AU580728B2 (en) Novel carbacyclins, process for their manufacture and their use as medicaments
PT76298B (en) Process for preparing 4"-epi erythromycin a and derivatives thereof as useful antibacterial agents
DE3064485D1 (en) Anthracycline glycosides, process for their preparation and therapeutical composition containing them
JPS55157569A (en) 33aryll7*88dihydroxyy66haloo11*44hydroxyphenyl** 2*3*4*55tetrahydroo1hh33benzazepine derivative
DE3164763D1 (en) Anthracycline glycosides, process for the preparation thereof, intermediate compounds and their preparation and pharmaceutical compositions
HUT44803A (en) Process for producing antracycline derivatives and pharmaceutical compositions containing them
MY102186A (en) Antitumor anthracycline glycosides, their preparation intermediate thereof, and compositions and use thereof
ES8306765A1 (es) "un procedimiento para preparar un derivado de antraciclina".
DE3064109D1 (en) Pseudotrisaccharides, their preparation and use as medicaments
DE69029781D1 (de) Anthracyclinglycosid-Derivate und Verfahren zu ihrer Herstellung
IL66028A0 (en) Saturated aminocyclitol derivatives,their preparation and pharmaceutical compositions containing them
DE3062340D1 (en) 1-n-alkylsisomicin derivatives, process for their preparation and their use as medicines
DE3060481D1 (en) Anthracycline glycosides, methods for the production thereof and therapeutical compositions containing same
ES529810A0 (es) Procedimiento para preparar compuestos complejos de (1, 2-difeniletilendiamina)-platino (ii)
IL91100A0 (en) 4-substituted anthracyclinones and anthracycline glycosides,their preparation and pharmaceutical compositions containing them
ES8203350A1 (es) Procedimiento para la fabricacion de derivados del pirazol
ES8203328A1 (es) Un procedimiento para la preparacion de 6-fluordihidroxifenilalaninas.
JPS55108889A (en) 4-o-methylaclacinomycin a and its preparation

Legal Events

Date Code Title Description
8339 Ceased/non-payment of the annual fee