DE3063660D1 - Spirobenzofuranones, their production and pharmaceutical compositions containing them - Google Patents

Spirobenzofuranones, their production and pharmaceutical compositions containing them

Info

Publication number
DE3063660D1
DE3063660D1 DE8080301431T DE3063660T DE3063660D1 DE 3063660 D1 DE3063660 D1 DE 3063660D1 DE 8080301431 T DE8080301431 T DE 8080301431T DE 3063660 T DE3063660 T DE 3063660T DE 3063660 D1 DE3063660 D1 DE 3063660D1
Authority
DE
Germany
Prior art keywords
spirobenzofuranones
production
pharmaceutical compositions
compositions containing
pharmaceutical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8080301431T
Other languages
German (de)
English (en)
Inventor
Hirosada Sugihara
Masazumi Watanabe
Mitsuru Kawada
Isuke Imada
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Pharmaceutical Co Ltd
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP5508279A external-priority patent/JPS55147271A/ja
Priority claimed from JP8055179A external-priority patent/JPS5931511B2/ja
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Application granted granted Critical
Publication of DE3063660D1 publication Critical patent/DE3063660D1/de
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/26Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D307/30Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/32Oxygen atoms
    • C07D307/33Oxygen atoms in position 2, the oxygen atom being in its keto or unsubstituted enol form
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/94Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom spiro-condensed with carbocyclic rings or ring systems, e.g. griseofulvins
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D493/00Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/10Spiro-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DE8080301431T 1979-05-04 1980-05-01 Spirobenzofuranones, their production and pharmaceutical compositions containing them Expired DE3063660D1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP5508279A JPS55147271A (en) 1979-05-04 1979-05-04 Spiro compound and its preparation
JP8055179A JPS5931511B2 (ja) 1979-06-25 1979-06-25 スピロ化合物およびその製造方法

Publications (1)

Publication Number Publication Date
DE3063660D1 true DE3063660D1 (en) 1983-07-14

Family

ID=26395929

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8080301431T Expired DE3063660D1 (en) 1979-05-04 1980-05-01 Spirobenzofuranones, their production and pharmaceutical compositions containing them

Country Status (10)

Country Link
EP (3) EP0038576B1 (enExample)
AT (1) AT383122B (enExample)
AU (1) AU534940B2 (enExample)
CA (3) CA1150287A (enExample)
DE (1) DE3063660D1 (enExample)
DK (1) DK153551C (enExample)
ES (4) ES491150A0 (enExample)
GR (1) GR66729B (enExample)
NO (1) NO155053C (enExample)
SU (1) SU1022658A3 (enExample)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK149891C (da) * 1977-12-27 1987-06-15 Takeda Chemical Industries Ltd Analogifremgangsmaade til fremstilling af spirobenzofuranon-forbindelser eller salte deraf med uorganiske eller organiske syrer eller alkalimetaller

Also Published As

Publication number Publication date
ES8205405A1 (es) 1982-06-01
EP0038576B1 (en) 1984-04-11
NO155053C (no) 1987-02-04
ES8104996A1 (es) 1981-05-16
CA1150287A (en) 1983-07-19
GR66729B (enExample) 1981-04-17
AT383122B (de) 1987-05-25
SU1022658A3 (ru) 1983-06-07
EP0038576A3 (en) 1981-11-18
ES8203873A1 (es) 1982-04-01
EP0018830A2 (en) 1980-11-12
ES502178A0 (es) 1982-04-01
ATA233880A (de) 1986-10-15
DK153551C (da) 1988-12-05
EP0038576A2 (en) 1981-10-28
CA1140562A (en) 1983-02-01
NO155053B (no) 1986-10-27
EP0018830B1 (en) 1983-06-08
EP0039091A1 (en) 1981-11-04
EP0039091B1 (en) 1984-05-30
ES497669A0 (es) 1982-06-01
DK184680A (da) 1980-11-05
ES502179A0 (es) 1982-04-01
ES491150A0 (es) 1981-05-16
DK153551B (da) 1988-07-25
NO801290L (no) 1980-11-05
AU5790380A (en) 1980-11-06
EP0018830A3 (en) 1980-12-10
ES8203874A1 (es) 1982-04-01
AU534940B2 (en) 1984-02-23
CA1138469A (en) 1982-12-28

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Legal Events

Date Code Title Description
8339 Ceased/non-payment of the annual fee