DE2966364D1 - Phenyl-alkanoic acid derivatives, the preparation thereof and pharmaceutical compositions containing them - Google Patents

Phenyl-alkanoic acid derivatives, the preparation thereof and pharmaceutical compositions containing them

Info

Publication number
DE2966364D1
DE2966364D1 DE7979301600T DE2966364T DE2966364D1 DE 2966364 D1 DE2966364 D1 DE 2966364D1 DE 7979301600 T DE7979301600 T DE 7979301600T DE 2966364 T DE2966364 T DE 2966364T DE 2966364 D1 DE2966364 D1 DE 2966364D1
Authority
DE
Germany
Prior art keywords
phenyl
preparation
pharmaceutical compositions
compositions containing
acid derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE7979301600T
Other languages
English (en)
Inventor
Ikuo Ueda
Yoshihiko Kitaura
Nobukiyo Konishi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fujisawa Pharmaceutical Co Ltd
Original Assignee
Fujisawa Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fujisawa Pharmaceutical Co Ltd filed Critical Fujisawa Pharmaceutical Co Ltd
Application granted granted Critical
Publication of DE2966364D1 publication Critical patent/DE2966364D1/de
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62Oxygen or sulfur atoms
    • C07D213/63One oxygen atom
    • C07D213/64One oxygen atom attached in position 2 or 6
    • C07D213/6432-Phenoxypyridines; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/49Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups
    • C07C205/56Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups bound to carbon atoms of six-membered aromatic rings and carboxyl groups bound to acyclic carbon atoms of the carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C253/00Preparation of carboxylic acid nitriles
    • C07C253/14Preparation of carboxylic acid nitriles by reaction of cyanides with halogen-containing compounds with replacement of halogen atoms by cyano groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/30Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/32Oxygen atoms
    • C07D209/34Oxygen atoms in position 2
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182Radicals derived from carboxylic acids
    • C07D295/185Radicals derived from carboxylic acids from aliphatic carboxylic acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Toxicology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyridine Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
DE7979301600T 1978-08-08 1979-08-07 Phenyl-alkanoic acid derivatives, the preparation thereof and pharmaceutical compositions containing them Expired DE2966364D1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB7832609 1978-08-08

Publications (1)

Publication Number Publication Date
DE2966364D1 true DE2966364D1 (en) 1983-12-08

Family

ID=10498927

Family Applications (1)

Application Number Title Priority Date Filing Date
DE7979301600T Expired DE2966364D1 (en) 1978-08-08 1979-08-07 Phenyl-alkanoic acid derivatives, the preparation thereof and pharmaceutical compositions containing them

Country Status (15)

Country Link
US (1) US4472433A (de)
EP (1) EP0008226B1 (de)
JP (1) JPS5551041A (de)
AR (2) AR228019A1 (de)
AT (1) ATE5188T1 (de)
AU (1) AU526877B2 (de)
CA (1) CA1127160A (de)
DE (1) DE2966364D1 (de)
DK (1) DK331679A (de)
ES (3) ES483252A1 (de)
GR (1) GR68102B (de)
HU (1) HU184114B (de)
IE (1) IE48676B1 (de)
PH (1) PH22340A (de)
SU (2) SU1199197A3 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4333951A (en) * 1977-11-15 1982-06-08 A. H. Robins Company, Inc. 2-Amino-6-biphenylacetic acids
US4477556A (en) * 1982-08-18 1984-10-16 E. I. Du Pont De Nemours And Company Acidic o-nitroaromatics as photoinhibitors of polymerization in positive working films
JPS61206716A (ja) * 1985-03-12 1986-09-13 Sato Hisao 搬送ロ−ル
US4911754A (en) * 1987-07-16 1990-03-27 American Cyanamid Company Herbicidally active aryloxy saturated 5-membered benzo fused hetero-cyclic compounds
ES2058024B1 (es) * 1992-11-10 1995-05-01 Menarini Lab Nuevo derivado arilpropionico, procedimiento de fabricacion del mismo y su utilizacion como analgesico.
JPH08511011A (ja) * 1993-06-07 1996-11-19 ゼネカ・リミテッド アニリン誘導体
TWI249519B (en) 2000-08-29 2006-02-21 Nobex Corp Immunoregulatory compounds and derivatives and methods of treating diseases therewith
US7186745B2 (en) 2001-03-06 2007-03-06 Astrazeneca Ab Indolone derivatives having vascular damaging activity
US8048924B2 (en) 2001-08-29 2011-11-01 Biocon Limited Methods and compositions employing 4-aminophenylacetic acid compounds
EP1773767B1 (de) 2004-07-07 2016-03-09 Biocon Limited Synthese von azogebundenen, das immunsystem regulierenden verbindungen
US10980807B2 (en) * 2016-02-09 2021-04-20 Inventisbio Llc Inhibitor of indoleamine-2,3-dioxygenase (IDO)

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1072998B (de) * 1960-01-14 Farbwerke Hoechst Aktiengesellschaft vormals Meister Lucius &. Brüning, Frankfurt/M Verfahren zur Herstellung von substituierten Diphenyläthern
FR1657M (fr) * 1961-01-14 1963-02-15 Merck Ag E 5-aleoxy-oxindoles
FR1516142A (fr) * 1967-01-24 1968-03-08 Rhone Poulenc Sa Nouveau procédé de préparation de dérivés de la phénothiazine
US3981905A (en) * 1970-03-16 1976-09-21 Boots Pure Drug Company Limited 2-(Substituted phenyl) propionic acids
JPS512358Y2 (de) * 1971-05-08 1976-01-23
BE795159A (fr) * 1972-02-08 1973-08-08 Thomae Gmbh Dr K Nouveaux acides butendiques, sels et derives de ces acides et procedes pour les preparer
CH569013A5 (de) * 1972-07-21 1975-11-14 Hoffmann La Roche
US4006161A (en) * 1973-12-26 1977-02-01 Eli Lilly And Company Thio-substituted 2-oxo-indolines
JPS511441A (ja) * 1974-06-19 1976-01-08 Fujisawa Pharmaceutical Co Fuenokishifuenirusakusanjudotaino seizoho
JPS511442A (ja) * 1974-06-19 1976-01-08 Fujisawa Pharmaceutical Co Fuenokishifuenirusakusanruino seizoho
JPS5487136A (en) * 1977-12-23 1979-07-11 Fujitsu Ltd Coupler between channels

Also Published As

Publication number Publication date
GR68102B (de) 1981-10-30
IE48676B1 (en) 1985-04-17
SU1053743A3 (ru) 1983-11-07
CA1127160A (en) 1982-07-06
EP0008226B1 (de) 1983-11-02
ES8106482A1 (es) 1981-07-01
ES483252A1 (es) 1980-09-01
PH22340A (en) 1988-08-12
SU1199197A3 (ru) 1985-12-15
ES492955A0 (es) 1981-07-01
HU184114B (en) 1984-07-30
IE791490L (en) 1980-02-08
EP0008226A3 (en) 1980-03-05
DK331679A (da) 1980-02-09
JPS5551041A (en) 1980-04-14
AR226446A1 (es) 1982-07-15
ES492954A0 (es) 1981-06-16
AU4946179A (en) 1981-02-05
EP0008226A2 (de) 1980-02-20
US4472433A (en) 1984-09-18
JPS6256861B2 (de) 1987-11-27
AR228019A1 (es) 1983-01-14
AU526877B2 (en) 1983-02-03
ATE5188T1 (de) 1983-11-15
ES8105690A1 (es) 1981-06-16

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Legal Events

Date Code Title Description
8328 Change in the person/name/address of the agent

Free format text: TUERK, D., DIPL.-CHEM. DR.RER.NAT. GILLE, C., DIPL.-ING., PAT.-ANW., 4000 DUESSELDORF

8339 Ceased/non-payment of the annual fee