DE2840910A1 - 7-dialkylamino-6-halogen-4-oxo-1,4- dihydro-3-chinolin-carbonsaeuren, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische mittel - Google Patents
7-dialkylamino-6-halogen-4-oxo-1,4- dihydro-3-chinolin-carbonsaeuren, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische mittelInfo
- Publication number
- DE2840910A1 DE2840910A1 DE19782840910 DE2840910A DE2840910A1 DE 2840910 A1 DE2840910 A1 DE 2840910A1 DE 19782840910 DE19782840910 DE 19782840910 DE 2840910 A DE2840910 A DE 2840910A DE 2840910 A1 DE2840910 A1 DE 2840910A1
- Authority
- DE
- Germany
- Prior art keywords
- oxo
- dihydro
- quinoline
- piperazinyl
- fluoro
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
- C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB39197/77A GB1598915A (en) | 1977-09-20 | 1977-09-20 | 1,4-dihydro-quinoline-3-carboxylic acid derivatives process for their preparation and composition containing them |
GB1298378 | 1978-04-03 |
Publications (1)
Publication Number | Publication Date |
---|---|
DE2840910A1 true DE2840910A1 (de) | 1979-04-05 |
Family
ID=26249396
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE19782840910 Granted DE2840910A1 (de) | 1977-09-20 | 1978-09-20 | 7-dialkylamino-6-halogen-4-oxo-1,4- dihydro-3-chinolin-carbonsaeuren, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische mittel |
Country Status (5)
Country | Link |
---|---|
DE (1) | DE2840910A1 (sv) |
ES (1) | ES473486A1 (sv) |
FR (2) | FR2403339A1 (sv) |
NL (1) | NL190520C (sv) |
SE (1) | SE444566B (sv) |
Cited By (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2939786A1 (de) * | 1978-09-29 | 1980-04-10 | Kyorin Seiyaku Kk | Chinolincarbonsaeurederivate und ihre verwendung |
EP0049355A1 (de) * | 1980-09-03 | 1982-04-14 | Bayer Ag | 7-Amino-1-cyclopropyl-4-oxo-1,4-dihydro-(naphthyridin oder chinolin)-3-carbonsäuren, Verfahren zu ihrer Herstellung und sie enthaltende Arzneimittel |
EP0117474A1 (de) * | 1983-02-25 | 1984-09-05 | Bayer Ag | Chinoloncarbonsäuren, Verfahren zu ihrer Herstellung sowie diese enthaltende antibakterielle Mittel |
EP0117473A1 (de) * | 1983-02-25 | 1984-09-05 | Bayer Ag | Chinoloncarbonsäuren, Verfahren zu ihrer Herstellung sowie diese enthaltende antibakterielle Mittel |
EP0126355A1 (de) * | 1983-05-18 | 1984-11-28 | Bayer Ag | 7-Amino-1-cyclopropyl-6,8-difluor-1,4-dihydro-4-oxo-3-chinolincarbonsäuren, Verfahren zu ihrer Herstellung sowie diese enthaltende antibakterielle Mittel |
EP0131839A1 (en) * | 1983-07-18 | 1985-01-23 | Abbott Laboratories | Quinoline antibacterial compounds |
WO1987003595A1 (en) | 1985-12-09 | 1987-06-18 | Chinoin Gyógyszer és Vegyészeti Termékek Gyára Rt. | Norfloxacin intermediate |
US4758567A (en) * | 1985-11-19 | 1988-07-19 | Rottapharm S.P.A. | 7-(4-amino-piperazinyl)- or 7-(4-chloro-piperazinyl)quinolinone and azaquinolinone derivatives and pharmaceutical compositions containing them |
LT3084B (en) | 1992-12-11 | 1994-11-25 | Krka Tovarna Zdravil | Process for preparing 1-substituted-6-fluoro-4-oxo-7-(1-piperazinyl)-1,4-dihydroquinoline-3-carboxylic acid,a novel intermediate useful in said process, and a process for preparing said intermediate |
LT3274B (en) | 1987-12-31 | 1995-05-25 | Krka Tovarna Zdravil | Process for preparing 1-substituted 6-fluoro-4-oxo-7-(1-piperazinyl)-1,4-dihydroquinoline-3-carboxylic acid |
WO2010131054A1 (en) | 2009-05-15 | 2010-11-18 | Bradford Pharma Limited | Redox drug derivatives |
WO2013068948A1 (en) | 2011-11-08 | 2013-05-16 | Actelion Pharmaceuticals Ltd | 2-oxo-oxazolidin-3,5-diyl antibiotic derivatives |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1979001144A1 (en) * | 1978-05-30 | 1979-12-27 | Fosroc International Ltd | Anchoring cartridges |
JPS5649382A (en) * | 1979-09-28 | 1981-05-02 | Dainippon Pharmaceut Co Ltd | 6-fluoro-7-cyclic amino-1,8-naphthylidine derivative and its salt |
SE440354B (sv) * | 1981-02-19 | 1985-07-29 | Kyorin Seiyaku Kk | Kinolinkarboxylsyraderivat |
DE3713672A1 (de) * | 1987-04-24 | 1988-11-17 | Bayer Ag | Verfahren zur herstellung von parenteral verabreichbaren chinoloncarbonsaeuren |
ES2186550B2 (es) * | 2001-06-27 | 2003-11-16 | Vita Lab | Nuevos derivados de oxazolidinonas como antibacterianos. |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4017622A (en) * | 1972-12-18 | 1977-04-12 | Dainippon Pharmaceutical Co., Ltd. | Piperazine derivatives |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5049286A (sv) * | 1973-09-04 | 1975-05-01 | ||
JPS5365887A (en) * | 1976-11-22 | 1978-06-12 | Kyorin Seiyaku Kk | Substituted quinoline*arboxylate and process for preparing same |
JPS53141286A (en) * | 1977-05-16 | 1978-12-08 | Kyorin Seiyaku Kk | Novel substituted quinolinecarboxylic acid |
FR2424919B1 (fr) * | 1978-05-03 | 1980-10-31 | Kyorin Seiyaku Kk | Acide quinoleinecarboxylique substitue et ses derives et leur utilisation comme agents antibacteriens |
-
1978
- 1978-09-07 SE SE7809411A patent/SE444566B/sv not_active IP Right Cessation
- 1978-09-08 FR FR7825937A patent/FR2403339A1/fr active Granted
- 1978-09-19 ES ES473486A patent/ES473486A1/es not_active Expired
- 1978-09-20 NL NLAANVRAGE7809591,A patent/NL190520C/xx not_active IP Right Cessation
- 1978-09-20 DE DE19782840910 patent/DE2840910A1/de active Granted
-
1981
- 1981-10-29 FR FR8120346A patent/FR2498931A1/fr active Granted
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4017622A (en) * | 1972-12-18 | 1977-04-12 | Dainippon Pharmaceutical Co., Ltd. | Piperazine derivatives |
Cited By (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2939786A1 (de) * | 1978-09-29 | 1980-04-10 | Kyorin Seiyaku Kk | Chinolincarbonsaeurederivate und ihre verwendung |
DE2939786C2 (de) * | 1978-09-29 | 1986-10-09 | Kyorin Seiyaku K.K., Tokio/Tokyo | Chinolincarbonsäure- und Naphthyridincarbonsäurederivate und ihre Verwendung |
EP0049355A1 (de) * | 1980-09-03 | 1982-04-14 | Bayer Ag | 7-Amino-1-cyclopropyl-4-oxo-1,4-dihydro-(naphthyridin oder chinolin)-3-carbonsäuren, Verfahren zu ihrer Herstellung und sie enthaltende Arzneimittel |
EP0117473A1 (de) * | 1983-02-25 | 1984-09-05 | Bayer Ag | Chinoloncarbonsäuren, Verfahren zu ihrer Herstellung sowie diese enthaltende antibakterielle Mittel |
EP0117474A1 (de) * | 1983-02-25 | 1984-09-05 | Bayer Ag | Chinoloncarbonsäuren, Verfahren zu ihrer Herstellung sowie diese enthaltende antibakterielle Mittel |
EP0126355A1 (de) * | 1983-05-18 | 1984-11-28 | Bayer Ag | 7-Amino-1-cyclopropyl-6,8-difluor-1,4-dihydro-4-oxo-3-chinolincarbonsäuren, Verfahren zu ihrer Herstellung sowie diese enthaltende antibakterielle Mittel |
EP0131839A1 (en) * | 1983-07-18 | 1985-01-23 | Abbott Laboratories | Quinoline antibacterial compounds |
US4758567A (en) * | 1985-11-19 | 1988-07-19 | Rottapharm S.P.A. | 7-(4-amino-piperazinyl)- or 7-(4-chloro-piperazinyl)quinolinone and azaquinolinone derivatives and pharmaceutical compositions containing them |
WO1987003595A1 (en) | 1985-12-09 | 1987-06-18 | Chinoin Gyógyszer és Vegyészeti Termékek Gyára Rt. | Norfloxacin intermediate |
LT3274B (en) | 1987-12-31 | 1995-05-25 | Krka Tovarna Zdravil | Process for preparing 1-substituted 6-fluoro-4-oxo-7-(1-piperazinyl)-1,4-dihydroquinoline-3-carboxylic acid |
LT3084B (en) | 1992-12-11 | 1994-11-25 | Krka Tovarna Zdravil | Process for preparing 1-substituted-6-fluoro-4-oxo-7-(1-piperazinyl)-1,4-dihydroquinoline-3-carboxylic acid,a novel intermediate useful in said process, and a process for preparing said intermediate |
WO2010131054A1 (en) | 2009-05-15 | 2010-11-18 | Bradford Pharma Limited | Redox drug derivatives |
WO2013068948A1 (en) | 2011-11-08 | 2013-05-16 | Actelion Pharmaceuticals Ltd | 2-oxo-oxazolidin-3,5-diyl antibiotic derivatives |
US9079922B2 (en) | 2011-11-08 | 2015-07-14 | Actelion Pharmaceuticals Ltd | 2-oxo-oxazolidin-3,5-diyl antibiotic derivatives |
Also Published As
Publication number | Publication date |
---|---|
NL190520C (nl) | 1994-04-05 |
FR2498931B1 (sv) | 1984-02-10 |
NL190520B (nl) | 1993-11-01 |
ES473486A1 (es) | 1979-11-01 |
SE444566B (sv) | 1986-04-21 |
NL7809591A (nl) | 1979-03-22 |
SE7809411L (sv) | 1979-03-21 |
FR2403339B1 (sv) | 1982-09-17 |
FR2403339A1 (fr) | 1979-04-13 |
FR2498931A1 (fr) | 1982-08-06 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DE3433924C2 (sv) | ||
AT393383B (de) | Verfahren zur herstellung von neuen benzoheterozyklischen verbindungen | |
DE2840910A1 (de) | 7-dialkylamino-6-halogen-4-oxo-1,4- dihydro-3-chinolin-carbonsaeuren, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische mittel | |
DE2939786C2 (de) | Chinolincarbonsäure- und Naphthyridincarbonsäurederivate und ihre Verwendung | |
US4292317A (en) | 1,4-Dihydro-quinoline-3-carboxylic acid derivatives, process for their preparation and compositions containing them | |
EP0049355B1 (de) | 7-Amino-1-cyclopropyl-4-oxo-1,4-dihydro-(naphthyridin oder chinolin)-3-carbonsäuren, Verfahren zu ihrer Herstellung und sie enthaltende Arzneimittel | |
DE69904333T2 (de) | Chinolinderivate | |
EP0259804B1 (de) | Pyrido [3,2,1-ij]-1,3,4-benzoxadiazinderivate, Verfahren zu deren Herstellung, entsprechende pharmazeutische Präparate und im Verfahren verwendbare Zwischenprodukte | |
DE3031767A1 (de) | Chinolincarbonsaeurederivate, verfahren zu ihrer herstellung und ihre verwendung | |
DE3786843T2 (de) | Chinolincarbonsäurederivate. | |
EP0126355A1 (de) | 7-Amino-1-cyclopropyl-6,8-difluor-1,4-dihydro-4-oxo-3-chinolincarbonsäuren, Verfahren zu ihrer Herstellung sowie diese enthaltende antibakterielle Mittel | |
DE69019859T2 (de) | Chinolon-Derivate und deren Salze, Verfahren zu deren Herstellung und diese enthaltende antibakterielle Wirkstoffe. | |
EP0276700A1 (de) | 8-Cyano-1-cyclopropyl-1,4-dihydro-4-oxo-3-chinolincarbonsäuren, Verfahren zu ihrer Herstellung und diese enthaltende antibakterielle Mittel | |
EP0206101A1 (de) | Verfahren zur Herstellung von 1,8-verbrückten 4-Chinolon-3-carbonsäuren | |
DE3205655C2 (sv) | ||
EP0155587B1 (de) | 1,7-Diamino-1,4-dihydro-4-oxo-3-(aza) chinolincarbonsäuren, Verfahren zu ihrer Herstellung sowie ihre Verwendung bei der Bekämpfung bakterieller Erkrankungen | |
EP0224178B1 (de) | 1-Cyclopropyl-6-fluor-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-chinolincarbonsäuren, Verfahren zu ihrer Herstellung sowie diese enthaltende antibakterielle Mittel | |
DE69004815T2 (de) | 1,8-Benzonaphthyridinderivate, ihre Herstellung und diese enthaltende Zusammensetzungen. | |
EP0253235B1 (de) | 1,8-verbrückte 4-Chinoloncarbonsäuren und diese enthaltende Arzneimittel | |
EP0235676B1 (de) | 7-(1-Pyrrolidinyl)-chinoloncarbonsaeure-Derivate | |
DE3880953T2 (de) | Chinolinderivate, Verfahren zur Herstellung davon und diese enthaltendes antibakterielles Mittel. | |
GB1598915A (en) | 1,4-dihydro-quinoline-3-carboxylic acid derivatives process for their preparation and composition containing them | |
DE3686201T2 (de) | Benzo(i,j)chinolizin-2-carbonsaeurederivate, ihre salze und hydrate, diese enthaltende pharmazeutische zubereitungen und verfahren zu ihrer herstellung. | |
DE1620151B1 (de) | 10-Piperazino-dibenzo(a,d)cycloheptadienderivate und Verfahren zu ihrer Herstellung | |
DE2043817C3 (de) | 1,4-Dihydro-3-carboxy-cyclopentano-(h)-chinolon-(4)-derivate, Verfahren zu deren Herstellung sowie deren Verwendung zur Bekämpfung antibakterieller Erkrankungen |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
8110 | Request for examination paragraph 44 | ||
D2 | Grant after examination | ||
8364 | No opposition during term of opposition | ||
8310 | Action for declaration of annulment | ||
8313 | Request for invalidation rejected/withdrawn |