DE2733233C3 - Verfahren zur Herstellung von trans-Phytol bzw. Vitamin K↓1↓ - Google Patents

Verfahren zur Herstellung von trans-Phytol bzw. Vitamin K↓1↓

Info

Publication number
DE2733233C3
DE2733233C3 DE2733233A DE2733233A DE2733233C3 DE 2733233 C3 DE2733233 C3 DE 2733233C3 DE 2733233 A DE2733233 A DE 2733233A DE 2733233 A DE2733233 A DE 2733233A DE 2733233 C3 DE2733233 C3 DE 2733233C3
Authority
DE
Germany
Prior art keywords
formula
methyl
trans
compound
ether
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE2733233A
Other languages
German (de)
English (en)
Other versions
DE2733233A1 (de
DE2733233B2 (de
Inventor
Max Dr. Zuerich Schmid
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AT548976A external-priority patent/AT360668B/de
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of DE2733233A1 publication Critical patent/DE2733233A1/de
Publication of DE2733233B2 publication Critical patent/DE2733233B2/de
Application granted granted Critical
Publication of DE2733233C3 publication Critical patent/DE2733233C3/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C46/00—Preparation of quinones
    • C07C46/02—Preparation of quinones by oxidation giving rise to quinoid structures
    • C07C46/06—Preparation of quinones by oxidation giving rise to quinoid structures of at least one hydroxy group on a six-membered aromatic ring
    • C07C46/08—Preparation of quinones by oxidation giving rise to quinoid structures of at least one hydroxy group on a six-membered aromatic ring with molecular oxygen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C17/00—Preparation of halogenated hydrocarbons
    • C07C17/26—Preparation of halogenated hydrocarbons by reactions involving an increase in the number of carbon atoms in the skeleton
    • C07C17/263—Preparation of halogenated hydrocarbons by reactions involving an increase in the number of carbon atoms in the skeleton by condensation reactions
    • C07C17/2632—Preparation of halogenated hydrocarbons by reactions involving an increase in the number of carbon atoms in the skeleton by condensation reactions involving an organo-magnesium compound, e.g. Grignard synthesis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/09—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by hydrolysis
    • C07C29/10—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by hydrolysis of ethers, including cyclic ethers, e.g. oxiranes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C41/00—Preparation of ethers; Preparation of compounds having groups, groups or groups
    • C07C41/48—Preparation of compounds having groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/30—Compounds having groups
    • C07C43/315—Compounds having groups containing oxygen atoms singly bound to carbon atoms not being acetal carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/51—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition
    • C07C45/511—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition involving transformation of singly bound oxygen functional groups to >C = O groups
    • C07C45/515—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition involving transformation of singly bound oxygen functional groups to >C = O groups the singly bound functional group being an acetalised, ketalised hemi-acetalised, or hemi-ketalised hydroxyl group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C47/00—Compounds having —CHO groups
    • C07C47/20—Unsaturated compounds having —CHO groups bound to acyclic carbon atoms
    • C07C47/277—Unsaturated compounds having —CHO groups bound to acyclic carbon atoms containing ether groups, groups, groups, or groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/10—Oxygen atoms
    • C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/09—Geometrical isomers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE2733233A 1976-07-26 1977-07-22 Verfahren zur Herstellung von trans-Phytol bzw. Vitamin K↓1↓ Expired DE2733233C3 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AT548976A AT360668B (de) 1976-07-26 1976-07-26 Verfahren zur herstellung von vitamin k1
CH735877 1977-06-15

Publications (3)

Publication Number Publication Date
DE2733233A1 DE2733233A1 (de) 1978-02-02
DE2733233B2 DE2733233B2 (de) 1979-05-17
DE2733233C3 true DE2733233C3 (de) 1985-07-18

Family

ID=25602223

Family Applications (1)

Application Number Title Priority Date Filing Date
DE2733233A Expired DE2733233C3 (de) 1976-07-26 1977-07-22 Verfahren zur Herstellung von trans-Phytol bzw. Vitamin K↓1↓

Country Status (4)

Country Link
DE (1) DE2733233C3 (OSRAM)
FR (1) FR2359808A1 (OSRAM)
GB (1) GB1575946A (OSRAM)
NL (1) NL7708281A (OSRAM)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0015436B1 (de) 1979-03-08 1982-02-03 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Verfahren zur stereospezifischen Herstellung von Verbindungen der Vitamin K1- und K2-Reihe sowie neue Ausgangsprodukte in diesem Verfahren

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK59702C (da) * 1939-08-31 1942-04-27 Hoffmann La Roche Fremgangsmaade til Fremstilling af Forbindelser med K-Vitaminvirkning.
US2839570A (en) * 1953-08-12 1958-06-17 Hoffmann La Roche Process for the production of 1-acyloxy-2-methyl-3-phytyl-4-hydroxy naphtalenes

Also Published As

Publication number Publication date
FR2359808B1 (OSRAM) 1979-06-01
FR2359808A1 (fr) 1978-02-24
DE2733233A1 (de) 1978-02-02
DE2733233B2 (de) 1979-05-17
NL7708281A (nl) 1978-01-30
GB1575946A (en) 1980-10-01

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Legal Events

Date Code Title Description
OAP Request for examination filed
OD Request for examination
8225 Change of the main classification

Ipc: C07C 50/14

8281 Inventor (new situation)

Free format text: SCHMID, MAX, DR., ZUERICH, CH

C3 Grant after two publication steps (3rd publication)
8339 Ceased/non-payment of the annual fee