DE2700697B2 - - Google Patents
Info
- Publication number
- DE2700697B2 DE2700697B2 DE19772700697 DE2700697A DE2700697B2 DE 2700697 B2 DE2700697 B2 DE 2700697B2 DE 19772700697 DE19772700697 DE 19772700697 DE 2700697 A DE2700697 A DE 2700697A DE 2700697 B2 DE2700697 B2 DE 2700697B2
- Authority
- DE
- Germany
- Prior art keywords
- fermenter
- heat exchanger
- oxygen
- entering
- culture medium
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims description 16
- 239000007789 gas Substances 0.000 claims description 16
- 239000001301 oxygen Substances 0.000 claims description 16
- 229910052760 oxygen Inorganic materials 0.000 claims description 16
- 238000007872 degassing Methods 0.000 claims description 14
- 239000007788 liquid Substances 0.000 claims description 14
- 235000015097 nutrients Nutrition 0.000 claims description 14
- 239000001963 growth medium Substances 0.000 claims description 11
- 239000002028 Biomass Substances 0.000 claims description 8
- 238000004519 manufacturing process Methods 0.000 claims description 8
- 239000000463 material Substances 0.000 claims description 5
- 239000011148 porous material Substances 0.000 claims description 5
- 108010027322 single cell proteins Proteins 0.000 claims description 4
- 102000004190 Enzymes Human genes 0.000 claims description 3
- 108090000790 Enzymes Proteins 0.000 claims description 3
- 239000003242 anti bacterial agent Substances 0.000 claims description 3
- 229940088710 antibiotic agent Drugs 0.000 claims description 3
- 238000000605 extraction Methods 0.000 claims description 3
- 238000011081 inoculation Methods 0.000 claims description 3
- 238000004065 wastewater treatment Methods 0.000 claims description 3
- 239000003517 fume Substances 0.000 claims description 2
- 238000005086 pumping Methods 0.000 claims description 2
- 238000005070 sampling Methods 0.000 claims description 2
- 101150029610 asun gene Proteins 0.000 claims 1
- 101150017817 ints13 gene Proteins 0.000 claims 1
- 238000000855 fermentation Methods 0.000 description 12
- 230000004151 fermentation Effects 0.000 description 12
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 10
- 239000000498 cooling water Substances 0.000 description 7
- 239000006260 foam Substances 0.000 description 7
- 244000286779 Hansenula anomala Species 0.000 description 6
- 244000005700 microbiome Species 0.000 description 6
- 238000000034 method Methods 0.000 description 5
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 4
- 230000015572 biosynthetic process Effects 0.000 description 4
- 239000000758 substrate Substances 0.000 description 4
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 3
- 229930195733 hydrocarbon Natural products 0.000 description 3
- 150000002430 hydrocarbons Chemical class 0.000 description 3
- 239000000203 mixture Substances 0.000 description 3
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 2
- MYMOFIZGZYHOMD-UHFFFAOYSA-N Dioxygen Chemical compound O=O MYMOFIZGZYHOMD-UHFFFAOYSA-N 0.000 description 2
- CSNNHWWHGAXBCP-UHFFFAOYSA-L Magnesium sulfate Chemical compound [Mg+2].[O-][S+2]([O-])([O-])[O-] CSNNHWWHGAXBCP-UHFFFAOYSA-L 0.000 description 2
- NBIIXXVUZAFLBC-UHFFFAOYSA-N Phosphoric acid Chemical compound OP(O)(O)=O NBIIXXVUZAFLBC-UHFFFAOYSA-N 0.000 description 2
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 description 2
- BFNBIHQBYMNNAN-UHFFFAOYSA-N ammonium sulfate Chemical compound N.N.OS(O)(=O)=O BFNBIHQBYMNNAN-UHFFFAOYSA-N 0.000 description 2
- 229910052921 ammonium sulfate Inorganic materials 0.000 description 2
- 235000011130 ammonium sulphate Nutrition 0.000 description 2
- 239000004202 carbamide Substances 0.000 description 2
- 229910052799 carbon Inorganic materials 0.000 description 2
- 239000007795 chemical reaction product Substances 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 238000005187 foaming Methods 0.000 description 2
- 230000017525 heat dissipation Effects 0.000 description 2
- 230000002503 metabolic effect Effects 0.000 description 2
- 238000002156 mixing Methods 0.000 description 2
- 229910052757 nitrogen Inorganic materials 0.000 description 2
- 230000002265 prevention Effects 0.000 description 2
- 239000000047 product Substances 0.000 description 2
- 108090000623 proteins and genes Proteins 0.000 description 2
- 102000004169 proteins and genes Human genes 0.000 description 2
- 239000007787 solid Substances 0.000 description 2
- LWIHDJKSTIGBAC-UHFFFAOYSA-K tripotassium phosphate Chemical compound [K+].[K+].[K+].[O-]P([O-])([O-])=O LWIHDJKSTIGBAC-UHFFFAOYSA-K 0.000 description 2
- 241000894006 Bacteria Species 0.000 description 1
- 239000004215 Carbon black (E152) Substances 0.000 description 1
- 241000233866 Fungi Species 0.000 description 1
- 229910000831 Steel Inorganic materials 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 239000013543 active substance Substances 0.000 description 1
- 238000010564 aerobic fermentation Methods 0.000 description 1
- 239000003570 air Substances 0.000 description 1
- 150000001298 alcohols Chemical class 0.000 description 1
- 229910000147 aluminium phosphate Inorganic materials 0.000 description 1
- 239000008346 aqueous phase Substances 0.000 description 1
- 230000000052 comparative effect Effects 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 238000012258 culturing Methods 0.000 description 1
- 230000006378 damage Effects 0.000 description 1
- 230000001419 dependent effect Effects 0.000 description 1
- 230000001066 destructive effect Effects 0.000 description 1
- 239000000284 extract Substances 0.000 description 1
- 230000002349 favourable effect Effects 0.000 description 1
- 239000003102 growth factor Substances 0.000 description 1
- 238000009630 liquid culture Methods 0.000 description 1
- 229910052943 magnesium sulfate Inorganic materials 0.000 description 1
- 235000019341 magnesium sulphate Nutrition 0.000 description 1
- 229910052751 metal Inorganic materials 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 238000010327 methods by industry Methods 0.000 description 1
- 230000000813 microbial effect Effects 0.000 description 1
- 230000002906 microbiologic effect Effects 0.000 description 1
- 239000012071 phase Substances 0.000 description 1
- 229910000160 potassium phosphate Inorganic materials 0.000 description 1
- 235000011009 potassium phosphates Nutrition 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 230000033764 rhythmic process Effects 0.000 description 1
- 230000000630 rising effect Effects 0.000 description 1
- 239000008247 solid mixture Substances 0.000 description 1
- 239000007921 spray Substances 0.000 description 1
- 238000005507 spraying Methods 0.000 description 1
- 229910001220 stainless steel Inorganic materials 0.000 description 1
- 239000010935 stainless steel Substances 0.000 description 1
- 239000010959 steel Substances 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 230000002459 sustained effect Effects 0.000 description 1
- 230000014616 translation Effects 0.000 description 1
- 238000011144 upstream manufacturing Methods 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/32—Processes using, or culture media containing, lower alkanols, i.e. C1 to C6
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
- C12M29/18—External loop; Means for reintroduction of fermented biomass or liquid percolate
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
- C12M29/20—Degassing; Venting; Bubble traps
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M47/00—Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
- C12M47/02—Separating microorganisms from the culture medium; Concentration of biomass
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M47/00—Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
- C12M47/14—Drying
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Sustainable Development (AREA)
- Virology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Medicinal Chemistry (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Priority Applications (16)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19772700697 DE2700697C3 (de) | 1977-01-10 | 1977-01-10 | Vorrichtung zur Gewinnung von mikrowellen Produkten |
| IN21/CAL/78A IN147215B (enrdf_load_stackoverflow) | 1977-01-10 | 1978-01-05 | |
| BE184134A BE862675A (fr) | 1977-01-10 | 1978-01-05 | Procede et installation pour la production microbiologique de proteines d'unicellulaires a partir d'ethanol |
| NL7800251A NL7800251A (nl) | 1977-01-10 | 1978-01-09 | Werkwijze en inrichting voor de microbiologische winning van eencellige proteine op basis van ethanol. |
| GB678/78A GB1579012A (en) | 1977-01-10 | 1978-01-09 | Method and apparatus for micro biological production of single cell protein |
| IT12413/78A IT1106734B (it) | 1977-01-10 | 1978-01-09 | Metodo e dispositivo per la produzione microbiologica di proteinada organisni unicellulari mediante l impiego di alcool etilico |
| FR7800436A FR2376898A1 (fr) | 1977-01-10 | 1978-01-09 | Procede et installation pour la production microbiologique de proteines d'unicellulaires a partir d'ethanol |
| BR7800143A BR7800143A (pt) | 1977-01-10 | 1978-01-10 | Processo para a obtencao microbiologica de proteina unicelular destinada a alimentacao de animais,e dispositivo para sua execucao |
| MX786765U MX7165E (es) | 1977-01-10 | 1978-01-10 | Procedimiento mejorado para la obtencion microbiologica de proteinas unicelulares a partir del etanol |
| JP91678A JPS53113089A (en) | 1977-01-10 | 1978-01-10 | Method and apparatus for producing mono cellular protein microbiologically by using ethanol as base material |
| AT16378A AT356616B (de) | 1977-01-10 | 1978-01-10 | Verfahren und vorrichtung zur mikrobiologischen gewinnung von einzellerprotein auf basis von aethanol |
| ES465852A ES465852A1 (es) | 1977-01-10 | 1978-01-10 | Un procedimiento para la obtencion microbiologica de protei-nas unicelulares a partir de etanol |
| MX1063978U MX7254E (es) | 1977-01-10 | 1978-01-10 | Aparato mejorado para la obtencion microbiologico de proteinas unicelulares a partir del etanol |
| AR270693A AR214660A1 (es) | 1977-01-10 | 1978-01-11 | Procedimiento y dispositivo para para la obtencion microbiologica de proteinas de microorganismos unicelulares a partir de etanol |
| ES474112A ES474112A1 (es) | 1977-01-10 | 1978-10-11 | Un dispositivo para la obtencion microbiologica de proteinasunicelulares a partir de etanol. |
| US06/885,957 US4808534A (en) | 1977-01-10 | 1986-07-15 | Method and apparatus for the microbiological production of single-cell protein |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19772700697 DE2700697C3 (de) | 1977-01-10 | 1977-01-10 | Vorrichtung zur Gewinnung von mikrowellen Produkten |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| DE2700697A1 DE2700697A1 (de) | 1978-07-20 |
| DE2700697B2 true DE2700697B2 (enrdf_load_stackoverflow) | 1980-04-03 |
| DE2700697C3 DE2700697C3 (de) | 1980-12-04 |
Family
ID=5998365
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE19772700697 Expired DE2700697C3 (de) | 1977-01-10 | 1977-01-10 | Vorrichtung zur Gewinnung von mikrowellen Produkten |
Country Status (3)
| Country | Link |
|---|---|
| BE (1) | BE862675A (enrdf_load_stackoverflow) |
| DE (1) | DE2700697C3 (enrdf_load_stackoverflow) |
| IN (1) | IN147215B (enrdf_load_stackoverflow) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3127335A1 (de) * | 1980-07-11 | 1982-06-09 | Centralen Institut po chimičeska promišlenost, Sofija | Verfahren und vorrichtung zum zuechten von aeroben mikroorganismen |
-
1977
- 1977-01-10 DE DE19772700697 patent/DE2700697C3/de not_active Expired
-
1978
- 1978-01-05 BE BE184134A patent/BE862675A/xx not_active IP Right Cessation
- 1978-01-05 IN IN21/CAL/78A patent/IN147215B/en unknown
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3127335A1 (de) * | 1980-07-11 | 1982-06-09 | Centralen Institut po chimičeska promišlenost, Sofija | Verfahren und vorrichtung zum zuechten von aeroben mikroorganismen |
Also Published As
| Publication number | Publication date |
|---|---|
| DE2700697A1 (de) | 1978-07-20 |
| DE2700697C3 (de) | 1980-12-04 |
| BE862675A (fr) | 1978-05-02 |
| IN147215B (enrdf_load_stackoverflow) | 1979-12-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| OAM | Search report available | ||
| OC | Search report available | ||
| OD | Request for examination | ||
| BI | Miscellaneous see part 2 | ||
| C3 | Grant after two publication steps (3rd publication) | ||
| 8339 | Ceased/non-payment of the annual fee |