DE261460C - - Google Patents
Info
- Publication number
- DE261460C DE261460C DENDAT261460D DE261460DA DE261460C DE 261460 C DE261460 C DE 261460C DE NDAT261460 D DENDAT261460 D DE NDAT261460D DE 261460D A DE261460D A DE 261460DA DE 261460 C DE261460 C DE 261460C
- Authority
- DE
- Germany
- Prior art keywords
- mercury
- solution
- alkali
- acid
- water
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- HEMHJVSKTPXQMS-UHFFFAOYSA-M sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 claims description 12
- IIACRCGMVDHOTQ-UHFFFAOYSA-N Sulfamic acid Chemical compound NS(O)(=O)=O IIACRCGMVDHOTQ-UHFFFAOYSA-N 0.000 claims description 8
- UKWHYYKOEPRTIC-UHFFFAOYSA-N Mercury(II) oxide Chemical compound [Hg]=O UKWHYYKOEPRTIC-UHFFFAOYSA-N 0.000 claims description 6
- 229910000474 mercury oxide Inorganic materials 0.000 claims description 5
- 239000000344 soap Substances 0.000 claims description 4
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 4
- 150000002731 mercury compounds Chemical class 0.000 claims description 3
- 229940100892 mercury compounds Drugs 0.000 claims description 3
- 239000003513 alkali Substances 0.000 claims description 2
- 150000001447 alkali salts Chemical class 0.000 claims description 2
- RCTYPNKXASFOBE-UHFFFAOYSA-M chloromercury Chemical compound [Hg]Cl RCTYPNKXASFOBE-UHFFFAOYSA-M 0.000 claims description 2
- 150000001875 compounds Chemical class 0.000 claims description 2
- 150000002730 mercury Chemical class 0.000 claims description 2
- 238000000034 method Methods 0.000 claims description 2
- 238000002360 preparation method Methods 0.000 claims description 2
- 239000002253 acid Substances 0.000 claims 2
- 230000005591 charge neutralization Effects 0.000 claims 1
- 230000001264 neutralization Effects 0.000 claims 1
- 238000006386 neutralization reaction Methods 0.000 claims 1
- KWYUFKZDYYNOTN-UHFFFAOYSA-M potassium hydroxide Chemical compound [OH-].[K+] KWYUFKZDYYNOTN-UHFFFAOYSA-M 0.000 description 9
- 239000000243 solution Substances 0.000 description 7
- WMFOQBRAJBCJND-UHFFFAOYSA-M lithium hydroxide Chemical compound [Li+].[OH-] WMFOQBRAJBCJND-UHFFFAOYSA-M 0.000 description 3
- 235000011121 sodium hydroxide Nutrition 0.000 description 3
- CPRMKOQKXYSDML-UHFFFAOYSA-M Rubidium hydroxide Chemical compound [OH-].[Rb+] CPRMKOQKXYSDML-UHFFFAOYSA-M 0.000 description 2
- QSHDDOUJBYECFT-UHFFFAOYSA-N mercury Chemical compound [Hg] QSHDDOUJBYECFT-UHFFFAOYSA-N 0.000 description 2
- 229910052753 mercury Inorganic materials 0.000 description 2
- 229910001987 mercury nitrate Inorganic materials 0.000 description 2
- DRXYRSRECMWYAV-UHFFFAOYSA-N nitrooxymercury Chemical compound [Hg+].[O-][N+]([O-])=O DRXYRSRECMWYAV-UHFFFAOYSA-N 0.000 description 2
- 150000003839 salts Chemical class 0.000 description 2
- 239000011780 sodium chloride Substances 0.000 description 2
- BVKZGUZCCUSVTD-UHFFFAOYSA-N Carbonic acid Chemical compound OC(O)=O BVKZGUZCCUSVTD-UHFFFAOYSA-N 0.000 description 1
- 239000003929 acidic solution Substances 0.000 description 1
- 239000012141 concentrate Substances 0.000 description 1
- 230000000249 desinfective Effects 0.000 description 1
- 239000000706 filtrate Substances 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- -1 mercury amido sulfonic acid salts Chemical class 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- GRYLNZFGIOXLOG-UHFFFAOYSA-N nitric acid Chemical compound O[N+]([O-])=O GRYLNZFGIOXLOG-UHFFFAOYSA-N 0.000 description 1
- 159000000001 potassium salts Chemical class 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 159000000000 sodium salts Chemical class 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C01—INORGANIC CHEMISTRY
- C01G—COMPOUNDS CONTAINING METALS NOT COVERED BY SUBCLASSES C01D OR C01F
- C01G13/00—Compounds of mercury
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Inorganic Chemistry (AREA)
- Detergent Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Description
KAISERLICHESIMPERIAL
PATENTAMT.PATENT OFFICE.
PATENTSCHRIFTPATENT LETTERING
- M 261460 - KLASSE 12/i. GRUPPE - M 261460 - CLASS 12 / i. GROUP
der Amidosulfonsäure.of sulfamic acid.
Patentiert im Deutschen Reiche vom 8. Mai 1912 ab.Patented in the German Empire on May 8, 1912.
Das vorliegende Verfahren bezweckt die Herstellung wasserlöslicher und alkalibesiändiger Quecksilberverbindungen der Amidosulfonsäure für den pharmazeutisch-medizinischen Gebrauch.The present process aims to produce water-soluble and alkali-resistant Mercury compounds of amidosulfonic acid for the pharmaceutical-medical Use.
Bekanntlich bildet die Amidosulfonsäure H2NSO3H mit Quecksilberoxyd oder Quecksilbernitrat eine Verbindung von der FormelAs is known, the sulfamic acid H 2 NSO 3 H forms a compound of the formula with mercury oxide or mercury nitrate
(H2NSO3HgO)2Hg^H2O(H 2 NSO 3 HgO) 2 Hg ^ H 2 O
Hg3N2(SO3H)2(OH)2^H2O,Hg 3 N 2 (SO 3 H) 2 (OH) 2 ^ H 2 O,
wenn man Amidosulfonsäure und Merkurinitrat bzw. Merkurioxyd in saurer Lösung fällt (vgl.
Chem. News, Vol. 74 [1896], S. 277,1. Sp. Mitte).
Dieses Salz ist in Wasser und selbst in verdünnter Salpetersäure nicht löslich und deshalb
medizinisch nicht brauchbar.
Es wurde nun gefunden, daß man schon in fast neutraler Lösung leicht lösliche, gegen
Alkalien und Seifen beständige Quecksilberverbindungen der Zusammensetzung HgNSO3K
bzw. HgNSO3Na erhält, wenn man die Alkalisalze der Amidosulfonsäure in alkalischer
Lösung mit Quecksilberoxyd oder mit einem Quecksilbersalz behandelt.when amidosulfonic acid and mercury nitrate or mercury oxide are precipitated in acidic solution (cf. Chem. News, Vol. 74 [1896], p. 277, 1. Col. middle). This salt is insoluble in water and even in dilute nitric acid and is therefore not medically useful.
It has now been found that easily soluble mercury compounds of the composition HgNSO 3 K or HgNSO 3 Na which are resistant to alkalis and soaps are obtained if the alkali salts of sulfamic acid are treated in alkaline solution with mercury oxide or with a mercury salt.
40 Teile Amidosulfonsäure werden mit Kalilauge stark alkalisch gemacht und dann mit 60 Teilen gefälltem Quecksilberoxyd erwärmt. Aus dem Filtrat scheidet sich nach geeignetem Einengen das weiße Kaliumsalz40 parts of sulfamic acid are made strongly alkaline with potassium hydroxide and then with 60 parts of precipitated mercury oxide are heated. The filtrate separates according to a suitable one Concentrate the white potassium salt
OC KO3SNHgH2O OC KO 3 SNHgH 2 O
ab. Dieses löst sich in warmem Wasser, besonders in Gegenwart von freier Kalilauge leicht auf und ist dann gegen Soda oder Seife beständig.away. This dissolves in warm water, especially in the presence of free potassium hydroxide easily and is then resistant to soda or soap.
40 Teile Amidosulfonsäure werden mit 10 prozentiger Natronlauge neutralisiert, dann mit der doppelten Menge derselben Natronlauge stark alkalisch gemacht und mit der warmen Lösung von 80 Teilen Quecksilberchlorid in 800 Teilen Wasser vermischt. Aus der alkalischen Lösung scheidet sich bei längerem Stehen das schön kristallisierte Natronsalz in einer Ausbeute von 140 Teilen ab.40 parts of sulfamic acid are 10 percent Sodium hydroxide solution neutralized, then made strongly alkaline with twice the amount of the same sodium hydroxide solution and with the warm one Solution of 80 parts of mercury chloride mixed in 800 parts of water. From the alkaline When standing for a long time, the nicely crystallized sodium salt separates into a solution Yield of 140 parts.
An Stelle von Kalilauge oder Natronlauge kann auch eine Lösung von Rubidiumhydroxyd oder Lithiumhydroxyd oder anderen stark basischen Stoffen verwendet werden.Instead of potassium hydroxide or caustic soda, a solution of rubidium hydroxide can also be used or lithium hydroxide or other strongly basic substances can be used.
Die quecksilberamidosulfonsauren Salze eignen sich zur Herstellung von desinfizierenden Lösungen oder anderen wegen ihres Quecksilbergehaltes wirksamen Präparaten in den Fällen, wo alkalische Reaktion zulässig ist.The mercury amido sulfonic acid salts are suitable for the production of disinfectant Solutions or other preparations that are effective because of their mercury content in the Cases where alkaline reaction is allowed.
Man braucht indessen zu diesem Zweck die reinen Salze nicht zu isolieren, sondern kann z. B. eine Quecksilberseife erhalten nach folgender Vorschrift:For this purpose, however, one does not need to isolate the pure salts, but can z. B. get a mercury soap according to the following rule:
Claims (1)
Verfahren zur Herstellung wasserlöslicher und alkalibeständiger Quecksilberverbindungen der Amidosulfonsäure, dadurch gekennzeichnet, daß man die Alkalisalze der Amidosulfonsäure in alkalischer Lösung mit Quecksilberoxyd oder einem Quecksilbersalz behandelt. Godfather τ-An saying:
Process for the preparation of water-soluble and alkali-resistant mercury compounds of amidosulphonic acid, characterized in that the alkali salts of amidosulphonic acid are treated in an alkaline solution with mercury oxide or a mercury salt.
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE261460C true DE261460C (en) |
Family
ID=519020
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DENDAT261460D Active DE261460C (en) |
Country Status (1)
| Country | Link |
|---|---|
| DE (1) | DE261460C (en) |
-
0
- DE DENDAT261460D patent/DE261460C/de active Active
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE3615348A1 (en) | METHOD FOR PRODUCING BASIC ZINC CARBONATE | |
| DE261460C (en) | ||
| DE708009C (en) | Process for the production of copper hydroxide | |
| DE495789C (en) | Process for the preparation of concentrated solutions of Trimercuri-diacetone hydrate | |
| DE399904C (en) | Process for the production of organic mercury compounds | |
| AT153216B (en) | Process for the preparation of complex gold keratin compounds. | |
| DE662648C (en) | Process for the production of metal sulfhydryl compounds from sulfur-rich keratin breakdown products | |
| DE267083C (en) | ||
| DE859458C (en) | Process for the preparation of disulfides | |
| DE710308C (en) | Process for the production of sodium-calcium-gold-generation compounds | |
| DE249726C (en) | ||
| DE514094C (en) | Process for the preparation of alkali salts of aromatic sulfonic halogenamides | |
| DE272517C (en) | ||
| DE228139C (en) | ||
| DE513205C (en) | Process for the preparation of derivatives of the aminoarylantimony compounds | |
| DE545693C (en) | Process for the production of oxidation products of sulfur-containing derivatives of higher fatty acids | |
| DE607291C (en) | Production of soluble compounds of sulfamic acid with mercury and alkali metals | |
| DE605074C (en) | Process for the preparation of compounds of sulfhydryl keratinic acid and similar reduced degradation products of keratin with organic compounds containing arsenic | |
| DE318625C (en) | ||
| DE716832C (en) | Process for the production of alkali thiosulfate | |
| DE491405C (en) | Process for the preparation of concentrated solutions of Trimercuri-diacetone hydrate | |
| DE956945C (en) | Process for the refining of arylalkanes in order to improve their oxidizability | |
| DE657975C (en) | Process for the production of hyposulfites | |
| DE629373C (en) | Process for the production of C, C-disubstituted compounds of barbituric acid | |
| DE689373C (en) | Process for the production of a sulfur-containing soap |