DE2327901A1 - Halocyclopropane - Google Patents
HalocyclopropaneInfo
- Publication number
- DE2327901A1 DE2327901A1 DE19732327901 DE2327901A DE2327901A1 DE 2327901 A1 DE2327901 A1 DE 2327901A1 DE 19732327901 DE19732327901 DE 19732327901 DE 2327901 A DE2327901 A DE 2327901A DE 2327901 A1 DE2327901 A1 DE 2327901A1
- Authority
- DE
- Germany
- Prior art keywords
- compound
- anesthetic
- general formula
- compounds
- anesthetics
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 150000001875 compounds Chemical class 0.000 claims description 20
- 230000003444 anaesthetic effect Effects 0.000 claims description 10
- 239000000203 mixture Substances 0.000 claims description 8
- 229910052731 fluorine Inorganic materials 0.000 claims description 5
- 238000000034 method Methods 0.000 claims description 5
- 229910052801 chlorine Inorganic materials 0.000 claims description 4
- 125000001309 chloro group Chemical group Cl* 0.000 claims description 4
- 125000001153 fluoro group Chemical group F* 0.000 claims description 4
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims description 3
- 239000001301 oxygen Substances 0.000 claims description 3
- 229910052760 oxygen Inorganic materials 0.000 claims description 3
- -1 difluorocarbene Chemical class 0.000 claims description 2
- WCYWZMWISLQXQU-UHFFFAOYSA-N methyl Chemical compound [CH3] WCYWZMWISLQXQU-UHFFFAOYSA-N 0.000 claims description 2
- 238000002360 preparation method Methods 0.000 claims description 2
- YCKRFDGAMUMZLT-UHFFFAOYSA-N Fluorine atom Chemical compound [F] YCKRFDGAMUMZLT-UHFFFAOYSA-N 0.000 claims 1
- 239000011737 fluorine Substances 0.000 claims 1
- 238000009835 boiling Methods 0.000 description 7
- 239000003193 general anesthetic agent Substances 0.000 description 7
- 229940035674 anesthetics Drugs 0.000 description 6
- 206010002091 Anaesthesia Diseases 0.000 description 4
- 230000037005 anaesthesia Effects 0.000 description 4
- 238000001816 cooling Methods 0.000 description 3
- BCQZXOMGPXTTIC-UHFFFAOYSA-N halothane Chemical compound FC(F)(F)C(Cl)Br BCQZXOMGPXTTIC-UHFFFAOYSA-N 0.000 description 3
- PGFXOWRDDHCDTE-UHFFFAOYSA-N hexafluoropropylene oxide Chemical compound FC(F)(F)C1(F)OC1(F)F PGFXOWRDDHCDTE-UHFFFAOYSA-N 0.000 description 3
- 239000003983 inhalation anesthetic agent Substances 0.000 description 3
- 238000003822 preparative gas chromatography Methods 0.000 description 3
- 230000011514 reflex Effects 0.000 description 3
- 238000012360 testing method Methods 0.000 description 3
- HEDRZPFGACZZDS-UHFFFAOYSA-N Chloroform Chemical compound ClC(Cl)Cl HEDRZPFGACZZDS-UHFFFAOYSA-N 0.000 description 2
- LVZWSLJZHVFIQJ-UHFFFAOYSA-N Cyclopropane Chemical compound C1CC1 LVZWSLJZHVFIQJ-UHFFFAOYSA-N 0.000 description 2
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 2
- 241000124008 Mammalia Species 0.000 description 2
- 241001465754 Metazoa Species 0.000 description 2
- 241000699670 Mus sp. Species 0.000 description 2
- GQPLMRYTRLFLPF-UHFFFAOYSA-N Nitrous Oxide Chemical compound [O-][N+]#N GQPLMRYTRLFLPF-UHFFFAOYSA-N 0.000 description 2
- 239000000470 constituent Substances 0.000 description 2
- 229960003132 halothane Drugs 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- HZVOZRGWRWCICA-UHFFFAOYSA-N methanediyl Chemical compound [CH2] HZVOZRGWRWCICA-UHFFFAOYSA-N 0.000 description 2
- 230000029058 respiratory gaseous exchange Effects 0.000 description 2
- 238000007363 ring formation reaction Methods 0.000 description 2
- MGSRCZKZVOBKFT-UHFFFAOYSA-N thymol Chemical compound CC(C)C1=CC=C(C)C=C1O MGSRCZKZVOBKFT-UHFFFAOYSA-N 0.000 description 2
- MSESDIYDWPAQBL-UHFFFAOYSA-N 1-chloro-1,2,2-trifluorocyclopropane Chemical compound FC1(F)CC1(F)Cl MSESDIYDWPAQBL-UHFFFAOYSA-N 0.000 description 1
- FPBWSPZHCJXUBL-UHFFFAOYSA-N 1-chloro-1-fluoroethene Chemical group FC(Cl)=C FPBWSPZHCJXUBL-UHFFFAOYSA-N 0.000 description 1
- VJOAJCOCCYFXPR-UHFFFAOYSA-N 3,3,3-trifluoro-2-methylprop-1-ene Chemical compound CC(=C)C(F)(F)F VJOAJCOCCYFXPR-UHFFFAOYSA-N 0.000 description 1
- XESZUVZBAMCAEJ-UHFFFAOYSA-N 4-tert-butylcatechol Chemical compound CC(C)(C)C1=CC=C(O)C(O)=C1 XESZUVZBAMCAEJ-UHFFFAOYSA-N 0.000 description 1
- WZKSXHQDXQKIQJ-UHFFFAOYSA-N F[C](F)F Chemical group F[C](F)F WZKSXHQDXQKIQJ-UHFFFAOYSA-N 0.000 description 1
- 239000005844 Thymol Substances 0.000 description 1
- 150000001336 alkenes Chemical class 0.000 description 1
- 229940035676 analgesics Drugs 0.000 description 1
- 239000000730 antalgic agent Substances 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 238000003776 cleavage reaction Methods 0.000 description 1
- 150000001923 cyclic compounds Chemical class 0.000 description 1
- 150000001942 cyclopropanes Chemical class 0.000 description 1
- 239000003085 diluting agent Substances 0.000 description 1
- 238000011156 evaluation Methods 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 239000007789 gas Substances 0.000 description 1
- 229940052308 general anesthetics halogenated hydrocarbons Drugs 0.000 description 1
- 150000008282 halocarbons Chemical class 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 230000010534 mechanism of action Effects 0.000 description 1
- XMSZANIMCDLNKA-UHFFFAOYSA-N methyl hypofluorite Chemical compound COF XMSZANIMCDLNKA-UHFFFAOYSA-N 0.000 description 1
- 239000001272 nitrous oxide Substances 0.000 description 1
- JRZJOMJEPLMPRA-UHFFFAOYSA-N olefin Natural products CCCCCCCC=C JRZJOMJEPLMPRA-UHFFFAOYSA-N 0.000 description 1
- 230000001766 physiological effect Effects 0.000 description 1
- 230000007017 scission Effects 0.000 description 1
- 239000003381 stabilizer Substances 0.000 description 1
- 229910001220 stainless steel Inorganic materials 0.000 description 1
- 239000010935 stainless steel Substances 0.000 description 1
- 238000010561 standard procedure Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 229960000790 thymol Drugs 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C17/00—Preparation of halogenated hydrocarbons
- C07C17/26—Preparation of halogenated hydrocarbons by reactions involving an increase in the number of carbon atoms in the skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C17/00—Preparation of halogenated hydrocarbons
- C07C17/26—Preparation of halogenated hydrocarbons by reactions involving an increase in the number of carbon atoms in the skeleton
- C07C17/263—Preparation of halogenated hydrocarbons by reactions involving an increase in the number of carbon atoms in the skeleton by condensation reactions
- C07C17/2637—Preparation of halogenated hydrocarbons by reactions involving an increase in the number of carbon atoms in the skeleton by condensation reactions between a compound containing only oxygen and possibly halogen as hetero-atoms and a halogenated hydrocarbon
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C23/00—Compounds containing at least one halogen atom bound to a ring other than a six-membered aromatic ring
- C07C23/02—Monocyclic halogenated hydrocarbons
- C07C23/04—Monocyclic halogenated hydrocarbons with a three-membered ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US25925372A | 1972-06-02 | 1972-06-02 | |
| US00258957A US3825606A (en) | 1972-06-02 | 1972-06-02 | Fluorocyclopropanes as inhalation anesthetics |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE2327901A1 true DE2327901A1 (de) | 1973-12-20 |
Family
ID=26946981
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE19732327901 Pending DE2327901A1 (de) | 1972-06-02 | 1973-06-01 | Halocyclopropane |
Country Status (7)
| Country | Link |
|---|---|
| JP (1) | JPS4948636A (enExample) |
| AR (1) | AR198835A1 (enExample) |
| AU (1) | AU5644173A (enExample) |
| DE (1) | DE2327901A1 (enExample) |
| FR (1) | FR2186224A1 (enExample) |
| IT (1) | IT1048124B (enExample) |
| NL (1) | NL7307559A (enExample) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5266895A (en) * | 1975-11-29 | 1977-06-02 | Asahi Carbon Co Ltd | Method of pelletizing carbon black |
| JP2016507590A (ja) * | 2013-02-27 | 2016-03-10 | ブルー キューブ アイピー エルエルシー | 塩素化プロペンを生成するための方法 |
-
1973
- 1973-05-29 IT IT2473573A patent/IT1048124B/it active
- 1973-05-30 AR AR24831373A patent/AR198835A1/es active
- 1973-05-30 NL NL7307559A patent/NL7307559A/xx unknown
- 1973-06-01 AU AU56441/73A patent/AU5644173A/en not_active Expired
- 1973-06-01 DE DE19732327901 patent/DE2327901A1/de active Pending
- 1973-06-01 JP JP6100573A patent/JPS4948636A/ja active Pending
- 1973-06-01 FR FR7320086A patent/FR2186224A1/fr active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| IT1048124B (it) | 1980-11-20 |
| JPS4948636A (enExample) | 1974-05-11 |
| AU5644173A (en) | 1974-12-05 |
| FR2186224B1 (enExample) | 1976-07-02 |
| AR198835A1 (es) | 1974-07-24 |
| NL7307559A (enExample) | 1973-12-04 |
| FR2186224A1 (en) | 1974-01-11 |
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