DE2307827A1 - Diaethylpyrocarbonat enthaltender stoff fuer veterinaermedizinische oder kosmetische verwendungszwecke - Google Patents
Diaethylpyrocarbonat enthaltender stoff fuer veterinaermedizinische oder kosmetische verwendungszweckeInfo
- Publication number
- DE2307827A1 DE2307827A1 DE19732307827 DE2307827A DE2307827A1 DE 2307827 A1 DE2307827 A1 DE 2307827A1 DE 19732307827 DE19732307827 DE 19732307827 DE 2307827 A DE2307827 A DE 2307827A DE 2307827 A1 DE2307827 A1 DE 2307827A1
- Authority
- DE
- Germany
- Prior art keywords
- substance
- pyrocarbonate
- healing
- scarring
- human
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000126 substance Substances 0.000 title claims description 14
- ZFTFAPZRGNKQPU-UHFFFAOYSA-N dicarbonic acid Chemical compound OC(=O)OC(O)=O ZFTFAPZRGNKQPU-UHFFFAOYSA-N 0.000 title claims description 5
- 239000002537 cosmetic Substances 0.000 title description 3
- 230000035876 healing Effects 0.000 claims description 14
- FFYPMLJYZAEMQB-UHFFFAOYSA-N diethyl pyrocarbonate Chemical compound CCOC(=O)OC(=O)OCC FFYPMLJYZAEMQB-UHFFFAOYSA-N 0.000 claims description 12
- 239000002674 ointment Substances 0.000 claims description 10
- 206010061218 Inflammation Diseases 0.000 claims description 9
- 230000004054 inflammatory process Effects 0.000 claims description 9
- 238000011282 treatment Methods 0.000 claims description 9
- 238000000034 method Methods 0.000 claims description 8
- 208000015181 infectious disease Diseases 0.000 claims description 7
- 230000002458 infectious effect Effects 0.000 claims description 7
- 238000004519 manufacturing process Methods 0.000 claims description 6
- 230000037390 scarring Effects 0.000 claims description 6
- 229910052783 alkali metal Inorganic materials 0.000 claims description 4
- 239000011230 binding agent Substances 0.000 claims description 4
- 235000005911 diet Nutrition 0.000 claims description 4
- 230000000378 dietary effect Effects 0.000 claims description 4
- 210000005075 mammary gland Anatomy 0.000 claims description 4
- 238000002560 therapeutic procedure Methods 0.000 claims description 4
- 239000010775 animal oil Substances 0.000 claims description 3
- 150000001875 compounds Chemical class 0.000 claims description 3
- 239000003925 fat Substances 0.000 claims description 3
- 208000004396 mastitis Diseases 0.000 claims description 3
- 235000019271 petrolatum Nutrition 0.000 claims description 3
- 239000000243 solution Substances 0.000 claims description 3
- 239000002904 solvent Substances 0.000 claims description 3
- 239000008158 vegetable oil Substances 0.000 claims description 3
- 239000001993 wax Substances 0.000 claims description 3
- YGYAWVDWMABLBF-UHFFFAOYSA-N Phosgene Chemical compound ClC(Cl)=O YGYAWVDWMABLBF-UHFFFAOYSA-N 0.000 claims description 2
- 239000000443 aerosol Substances 0.000 claims description 2
- -1 alkali metal ethyl carbonate Chemical class 0.000 claims description 2
- 150000001340 alkali metals Chemical class 0.000 claims description 2
- 239000003814 drug Substances 0.000 claims description 2
- RIFGWPKJUGCATF-UHFFFAOYSA-N ethyl chloroformate Chemical compound CCOC(Cl)=O RIFGWPKJUGCATF-UHFFFAOYSA-N 0.000 claims description 2
- 238000011065 in-situ storage Methods 0.000 claims description 2
- 229940057995 liquid paraffin Drugs 0.000 claims description 2
- 239000006210 lotion Substances 0.000 claims description 2
- CQDGTJPVBWZJAZ-UHFFFAOYSA-N monoethyl carbonate Chemical compound CCOC(O)=O CQDGTJPVBWZJAZ-UHFFFAOYSA-N 0.000 claims description 2
- 239000003826 tablet Substances 0.000 claims description 2
- 229930195733 hydrocarbon Natural products 0.000 claims 3
- 150000002430 hydrocarbons Chemical class 0.000 claims 3
- 239000004215 Carbon black (E152) Substances 0.000 claims 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims 2
- 235000013311 vegetables Nutrition 0.000 claims 2
- 239000012895 dilution Substances 0.000 claims 1
- 238000010790 dilution Methods 0.000 claims 1
- 239000004744 fabric Substances 0.000 claims 1
- 230000001737 promoting effect Effects 0.000 claims 1
- 230000001225 therapeutic effect Effects 0.000 claims 1
- 206010052428 Wound Diseases 0.000 description 15
- 208000027418 Wounds and injury Diseases 0.000 description 15
- 239000000047 product Substances 0.000 description 12
- 208000033809 Suppuration Diseases 0.000 description 7
- 235000013336 milk Nutrition 0.000 description 7
- 239000008267 milk Substances 0.000 description 7
- 210000004080 milk Anatomy 0.000 description 7
- 241000283690 Bos taurus Species 0.000 description 6
- 210000000481 breast Anatomy 0.000 description 4
- 238000002360 preparation method Methods 0.000 description 4
- 210000001519 tissue Anatomy 0.000 description 4
- 241001465754 Metazoa Species 0.000 description 3
- 239000003242 anti bacterial agent Substances 0.000 description 3
- 229940088710 antibiotic agent Drugs 0.000 description 3
- 238000001035 drying Methods 0.000 description 3
- 210000004907 gland Anatomy 0.000 description 3
- 239000000203 mixture Substances 0.000 description 3
- 208000032544 Cicatrix Diseases 0.000 description 2
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Chemical compound OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 description 2
- 239000004264 Petrolatum Substances 0.000 description 2
- 230000000844 anti-bacterial effect Effects 0.000 description 2
- 230000036528 appetite Effects 0.000 description 2
- 235000019789 appetite Nutrition 0.000 description 2
- 230000015572 biosynthetic process Effects 0.000 description 2
- OSGAYBCDTDRGGQ-UHFFFAOYSA-L calcium sulfate Inorganic materials [Ca+2].[O-]S([O-])(=O)=O OSGAYBCDTDRGGQ-UHFFFAOYSA-L 0.000 description 2
- ZOMBKNNSYQHRCA-UHFFFAOYSA-J calcium sulfate hemihydrate Chemical compound O.[Ca+2].[Ca+2].[O-]S([O-])(=O)=O.[O-]S([O-])(=O)=O ZOMBKNNSYQHRCA-UHFFFAOYSA-J 0.000 description 2
- 238000006243 chemical reaction Methods 0.000 description 2
- 235000013365 dairy product Nutrition 0.000 description 2
- 239000002781 deodorant agent Substances 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 239000011507 gypsum plaster Substances 0.000 description 2
- 238000002347 injection Methods 0.000 description 2
- 239000007924 injection Substances 0.000 description 2
- 239000002085 irritant Substances 0.000 description 2
- 231100000021 irritant Toxicity 0.000 description 2
- 230000000622 irritating effect Effects 0.000 description 2
- 229940066842 petrolatum Drugs 0.000 description 2
- 231100000241 scar Toxicity 0.000 description 2
- 230000037387 scars Effects 0.000 description 2
- 230000001954 sterilising effect Effects 0.000 description 2
- 238000004659 sterilization and disinfection Methods 0.000 description 2
- 231100000027 toxicology Toxicity 0.000 description 2
- 210000000689 upper leg Anatomy 0.000 description 2
- 206010002091 Anaesthesia Diseases 0.000 description 1
- 208000031295 Animal disease Diseases 0.000 description 1
- 241000894006 Bacteria Species 0.000 description 1
- 241000272201 Columbiformes Species 0.000 description 1
- 241000101840 Ctenolophon parvifolius Species 0.000 description 1
- ASXBYYWOLISCLQ-UHFFFAOYSA-N Dihydrostreptomycin Natural products O1C(CO)C(O)C(O)C(NC)C1OC1C(CO)(O)C(C)OC1OC1C(N=C(N)N)C(O)C(N=C(N)N)C(O)C1O ASXBYYWOLISCLQ-UHFFFAOYSA-N 0.000 description 1
- 241000282326 Felis catus Species 0.000 description 1
- 206010020843 Hyperthermia Diseases 0.000 description 1
- 208000029549 Muscle injury Diseases 0.000 description 1
- 206010028980 Neoplasm Diseases 0.000 description 1
- 206010030113 Oedema Diseases 0.000 description 1
- 241000283973 Oryctolagus cuniculus Species 0.000 description 1
- 208000012868 Overgrowth Diseases 0.000 description 1
- 206010037888 Rash pustular Diseases 0.000 description 1
- 241000191967 Staphylococcus aureus Species 0.000 description 1
- 230000035508 accumulation Effects 0.000 description 1
- 238000009825 accumulation Methods 0.000 description 1
- 230000002378 acidificating effect Effects 0.000 description 1
- 235000013334 alcoholic beverage Nutrition 0.000 description 1
- 230000001476 alcoholic effect Effects 0.000 description 1
- 150000001338 aliphatic hydrocarbons Chemical class 0.000 description 1
- 230000037005 anaesthesia Effects 0.000 description 1
- 230000003385 bacteriostatic effect Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000037396 body weight Effects 0.000 description 1
- 244000309466 calf Species 0.000 description 1
- 239000000969 carrier Substances 0.000 description 1
- 239000003518 caustics Substances 0.000 description 1
- 235000013351 cheese Nutrition 0.000 description 1
- 239000007795 chemical reaction product Substances 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 229940110456 cocoa butter Drugs 0.000 description 1
- 235000019868 cocoa butter Nutrition 0.000 description 1
- 230000006378 damage Effects 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 230000018044 dehydration Effects 0.000 description 1
- 238000006297 dehydration reaction Methods 0.000 description 1
- 230000001877 deodorizing effect Effects 0.000 description 1
- ASXBYYWOLISCLQ-HZYVHMACSA-N dihydrostreptomycin Chemical compound CN[C@H]1[C@H](O)[C@@H](O)[C@H](CO)O[C@H]1O[C@@H]1[C@](CO)(O)[C@H](C)O[C@H]1O[C@@H]1[C@@H](NC(N)=N)[C@H](O)[C@@H](NC(N)=N)[C@H](O)[C@H]1O ASXBYYWOLISCLQ-HZYVHMACSA-N 0.000 description 1
- 229960002222 dihydrostreptomycin Drugs 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 238000009826 distribution Methods 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 210000003608 fece Anatomy 0.000 description 1
- 238000000855 fermentation Methods 0.000 description 1
- 230000004151 fermentation Effects 0.000 description 1
- 210000002082 fibula Anatomy 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 230000000855 fungicidal effect Effects 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 230000012010 growth Effects 0.000 description 1
- 230000036031 hyperthermia Effects 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 238000003780 insertion Methods 0.000 description 1
- 230000037431 insertion Effects 0.000 description 1
- 230000002045 lasting effect Effects 0.000 description 1
- 231100000636 lethal dose Toxicity 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 235000013372 meat Nutrition 0.000 description 1
- 230000003641 microbiacidal effect Effects 0.000 description 1
- 210000003097 mucus Anatomy 0.000 description 1
- 230000036407 pain Effects 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 230000035935 pregnancy Effects 0.000 description 1
- 208000029561 pustule Diseases 0.000 description 1
- 238000010517 secondary reaction Methods 0.000 description 1
- 238000009958 sewing Methods 0.000 description 1
- 239000010902 straw Substances 0.000 description 1
- 230000001629 suppression Effects 0.000 description 1
- 210000002303 tibia Anatomy 0.000 description 1
- 230000002110 toxicologic effect Effects 0.000 description 1
- 229940099259 vaseline Drugs 0.000 description 1
- 235000015112 vegetable and seed oil Nutrition 0.000 description 1
- 235000019871 vegetable fat Nutrition 0.000 description 1
- 239000003981 vehicle Substances 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/265—Esters, e.g. nitroglycerine, selenocyanates of carbonic, thiocarbonic, or thiocarboxylic acids, e.g. thioacetic acid, xanthogenic acid, trithiocarbonic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Dermatology (AREA)
- Emergency Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7205365A FR2171966B1 (enExample) | 1972-02-17 | 1972-02-17 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE2307827A1 true DE2307827A1 (de) | 1973-08-23 |
Family
ID=9093657
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE19732307827 Pending DE2307827A1 (de) | 1972-02-17 | 1973-02-16 | Diaethylpyrocarbonat enthaltender stoff fuer veterinaermedizinische oder kosmetische verwendungszwecke |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US3920847A (enExample) |
| BE (1) | BE795132A (enExample) |
| DE (1) | DE2307827A1 (enExample) |
| FR (1) | FR2171966B1 (enExample) |
| GB (1) | GB1392905A (enExample) |
| NL (1) | NL7301984A (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2506482C3 (de) * | 1975-02-15 | 1978-11-30 | Bayer Ag, 5090 Leverkusen | Organische Dicarbonate enthaltendes Mittel zur Bodendesinfektion und Bekämpfung von Pflanzenkrankheiten |
| US4080309A (en) * | 1975-04-25 | 1978-03-21 | Henkel Kommanditgesellschaft Auf Aktien (Henkel Kgaa) | Carbonic acid ester perfumes |
| DE3231397A1 (de) * | 1982-08-24 | 1984-03-01 | Bayer Ag, 5090 Leverkusen | Verwendung von carbonylverbindungen und/oder heteroanalogen carbonylverbindungen als stabilisierungsmittel fuer pyrokohlensaeuredialkylester enthaltende loesungen und, die genannten verbindungen enthaltende, polyisocyanat-zubereitungen |
| US20040033938A1 (en) * | 2000-09-12 | 2004-02-19 | Britten Nancy J. | Cyclooxygenase-2 inhibitor and antibacterial agent combination for intramammary treatment of mastitis |
| US20080153894A1 (en) * | 2002-12-19 | 2008-06-26 | Pharmacia Corporation | Cyclooxygenase-2 inhibitor and antibacterial agent combination for intramammary treatment of mastitis |
| WO2014121343A1 (en) * | 2013-02-08 | 2014-08-14 | Luoda Pharma Pty Limited | Methods of treating microbial infections, including mastitis |
| JP2016507532A (ja) * | 2013-02-08 | 2016-03-10 | ルオダ ファーマ ピーティーワイ リミテッド | 局所微生物感染を処置する方法 |
| GB2559369A (en) * | 2017-02-03 | 2018-08-08 | Vornagain Ltd | Pharmaceutical and cleaning compositions and their use in treatment |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2910400A (en) * | 1956-04-13 | 1959-10-27 | Bayer Ag | Process of preserving carbohydratecontaining perishable material |
-
1972
- 1972-02-17 FR FR7205365A patent/FR2171966B1/fr not_active Expired
-
1973
- 1973-02-08 BE BE795132D patent/BE795132A/xx unknown
- 1973-02-13 US US332171A patent/US3920847A/en not_active Expired - Lifetime
- 1973-02-13 NL NL7301984A patent/NL7301984A/xx unknown
- 1973-02-16 DE DE19732307827 patent/DE2307827A1/de active Pending
- 1973-02-19 GB GB800273A patent/GB1392905A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| FR2171966A1 (enExample) | 1973-09-28 |
| GB1392905A (en) | 1975-05-07 |
| NL7301984A (enExample) | 1973-08-21 |
| US3920847A (en) | 1975-11-18 |
| FR2171966B1 (enExample) | 1975-03-14 |
| BE795132A (fr) | 1973-05-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| OHW | Rejection |