DE2243014C2 - Verfahren zur Herstellung eines homogenen, gefriergetrockneten Serum- oder Plasmaproduktes - Google Patents

Verfahren zur Herstellung eines homogenen, gefriergetrockneten Serum- oder Plasmaproduktes

Info

Publication number
DE2243014C2
DE2243014C2 DE2243014A DE2243014A DE2243014C2 DE 2243014 C2 DE2243014 C2 DE 2243014C2 DE 2243014 A DE2243014 A DE 2243014A DE 2243014 A DE2243014 A DE 2243014A DE 2243014 C2 DE2243014 C2 DE 2243014C2
Authority
DE
Germany
Prior art keywords
serum
plasma
product
particles
freezing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE2243014A
Other languages
German (de)
English (en)
Other versions
DE2243014A1 (de
Inventor
Anglis Ray Wilmington Del. Briggs
Thomas John Havertown Pa. Maxwell
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
EIDP Inc
Original Assignee
EI Du Pont de Nemours and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by EI Du Pont de Nemours and Co filed Critical EI Du Pont de Nemours and Co
Publication of DE2243014A1 publication Critical patent/DE2243014A1/de
Application granted granted Critical
Publication of DE2243014C2 publication Critical patent/DE2243014C2/de
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10—Preservation of living parts
    • A01N1/12—Chemical aspects of preservation
    • A01N1/122—Preservation or perfusion media
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10—Preservation of living parts
    • A01N1/12—Chemical aspects of preservation
    • A01N1/122—Preservation or perfusion media
    • A01N1/125—Freeze protecting agents, e.g. cryoprotectants or osmolarity regulators
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10—Preservation of living parts
    • A01N1/16—Physical preservation processes
    • A01N1/162—Temperature processes, e.g. following predefined temperature changes over time
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/96—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood or serum control standard
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2496/00—Reference solutions for assays of biological material
    • G01N2496/05—Reference solutions for assays of biological material containing blood cells or plasma

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Wood Science & Technology (AREA)
  • Cell Biology (AREA)
  • Dentistry (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • Environmental Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Zoology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DE2243014A 1971-09-03 1972-09-01 Verfahren zur Herstellung eines homogenen, gefriergetrockneten Serum- oder Plasmaproduktes Expired DE2243014C2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US17783471A 1971-09-03 1971-09-03

Publications (2)

Publication Number Publication Date
DE2243014A1 DE2243014A1 (de) 1973-03-08
DE2243014C2 true DE2243014C2 (de) 1986-05-28

Family

ID=22650148

Family Applications (1)

Application Number Title Priority Date Filing Date
DE2243014A Expired DE2243014C2 (de) 1971-09-03 1972-09-01 Verfahren zur Herstellung eines homogenen, gefriergetrockneten Serum- oder Plasmaproduktes

Country Status (9)

Country Link
JP (1) JPS5727422B2 (enExample)
CA (1) CA980249A (enExample)
CH (1) CH574590A5 (enExample)
DE (1) DE2243014C2 (enExample)
FR (1) FR2154452B1 (enExample)
GB (1) GB1395651A (enExample)
IT (1) IT1043886B (enExample)
NL (1) NL174429C (enExample)
SE (1) SE425461B (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5143185U (enExample) * 1974-09-27 1976-03-30
JPS5350668U (enExample) * 1976-10-02 1978-04-28
US4211015A (en) * 1978-01-18 1980-07-08 Baxter Travenol Laboratories, Inc. Method and apparatus for making novel particulate compositions
DE3107060A1 (de) * 1981-02-25 1982-09-09 Boehringer Mannheim Gmbh, 6800 Mannheim Kontroll- oder eichserum und verfahren zu seiner herstellung
JPS61111909U (enExample) * 1984-12-24 1986-07-15
DE69534151T2 (de) * 1994-02-22 2006-01-12 Nippon Telegraph And Telephone Corp. Gefriergetrocknete Blutzellen, Stammzellen und Plättchen und Verfahren zu deren Herstellung
IL120202A (en) * 1996-03-07 2001-03-19 Akzo Nobel Nv Container with freeze-dried vaccine components
CN1685210A (zh) * 2001-01-02 2005-10-19 苏帕契勒技术控股有限公司 为组织学和病理学检验制备组织样品的方法和系统
US6656380B2 (en) 2001-10-16 2003-12-02 Supachill Technologies Pty. Ltd. Super-coolable composition having long-duration phase change capability, process for preparation of same, process for super-cooling same and articles comprising same
GB0305133D0 (en) * 2003-03-06 2003-04-09 Sinvent As Product
WO2021158759A2 (en) * 2020-02-04 2021-08-12 Regeneron Pharmaceuticals, Inc. Target residual moisture content for lyophilized drug product
WO2024053643A1 (ja) * 2022-09-06 2024-03-14 株式会社アルバック 乾燥血漿

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3228838A (en) * 1959-04-23 1966-01-11 Union Carbide Corp Preservation of biological substances
US3177117A (en) * 1961-12-26 1965-04-06 Joseph F Saunders Process for freezing blood
US3281950A (en) * 1964-10-05 1966-11-01 Kautz Kurt Freeze-drying process

Also Published As

Publication number Publication date
NL174429C (nl) 1984-06-18
JPS5727422B2 (enExample) 1982-06-10
FR2154452A1 (enExample) 1973-05-11
CH574590A5 (enExample) 1976-04-15
GB1395651A (en) 1975-05-29
NL174429B (nl) 1984-01-16
NL7211923A (enExample) 1973-03-06
CA980249A (en) 1975-12-23
IT1043886B (it) 1980-02-29
JPS4835027A (enExample) 1973-05-23
DE2243014A1 (de) 1973-03-08
FR2154452B1 (enExample) 1976-03-05
SE425461B (sv) 1982-10-04

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Legal Events

Date Code Title Description
OD Request for examination
D2 Grant after examination
8364 No opposition during term of opposition