DE2143614A1 - 2-substituierte benzimidazole und verfahren zu deren herstellung - Google Patents

2-substituierte benzimidazole und verfahren zu deren herstellung

Info

Publication number
DE2143614A1
DE2143614A1 DE2143614A DE2143614A DE2143614A1 DE 2143614 A1 DE2143614 A1 DE 2143614A1 DE 2143614 A DE2143614 A DE 2143614A DE 2143614 A DE2143614 A DE 2143614A DE 2143614 A1 DE2143614 A1 DE 2143614A1
Authority
DE
Germany
Prior art keywords
alkyl
phenyl
benzimidazole
pyrrolidinyl
general formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
DE2143614A
Other languages
German (de)
English (en)
Inventor
Grover Cleveland Helsley
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AH Robins Co Inc
Original Assignee
AH Robins Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by AH Robins Co Inc filed Critical AH Robins Co Inc
Publication of DE2143614A1 publication Critical patent/DE2143614A1/de
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DE2143614A 1970-08-31 1971-08-31 2-substituierte benzimidazole und verfahren zu deren herstellung Pending DE2143614A1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US6854970A 1970-08-31 1970-08-31

Publications (1)

Publication Number Publication Date
DE2143614A1 true DE2143614A1 (de) 1973-04-05

Family

ID=22083267

Family Applications (1)

Application Number Title Priority Date Filing Date
DE2143614A Pending DE2143614A1 (de) 1970-08-31 1971-08-31 2-substituierte benzimidazole und verfahren zu deren herstellung

Country Status (4)

Country Link
AU (1) AU448887B2 (enExample)
DE (1) DE2143614A1 (enExample)
FR (1) FR2103639B1 (enExample)
GB (1) GB1354554A (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE59911249D1 (de) 1998-11-03 2005-01-13 Abbott Gmbh & Co Kg Substituierte 2-phenylbenzimidazole, deren herstellung und anwendung
JP2003525207A (ja) * 1999-06-02 2003-08-26 ワーナー−ランバート・カンパニー、リミテッド、ライアビリティ、カンパニー 薬剤として有用なアミノ複素環
US7244847B2 (en) * 2002-02-06 2007-07-17 Isis Pharmaceuticals, Inc. Benzimidazole compounds
US6939877B2 (en) 2002-09-12 2005-09-06 Wyeth Antidepressant piperidine derivatives of heterocycle-fused benzodioxans
AU2003298839A1 (en) 2002-12-03 2004-06-23 Isis Pharmaceuticals, Inc. Benzimidazoles and analogs thereof as antivirals
TWI375673B (en) 2005-04-11 2012-11-01 Abbott Lab 1h-benzimidazole-4-carboxamides substituted with a quaternary carbon at the 2-position are potent parp inhibitors
WO2006110683A1 (en) 2005-04-11 2006-10-19 Abbott Laboratories 2-substituted-1h-benzimidazole-4-carboxamides are parp inhibitors
CA2628461C (en) 2005-11-15 2013-09-24 Abbott Laboratories Substituted 1h-benzimidazole-4-carboxamides are potent parp inhibitors
EP2012780B1 (en) 2006-05-02 2012-04-11 Abbott Laboratories Substituted 1h-benzimidazole-4-carboxamides are potent parp inhibitors
US8067613B2 (en) 2007-07-16 2011-11-29 Abbott Laboratories Benzimidazole poly(ADP ribose)polymerase inhibitors
WO2010083199A1 (en) 2009-01-19 2010-07-22 Abbott Laboratories Benzthiazole inhibitors of poly(adp-ribose)polymerase
CN103896915A (zh) * 2014-04-01 2014-07-02 中国药科大学 苯并咪唑类衍生物、其制备方法及其在医药上的应用

Also Published As

Publication number Publication date
GB1354554A (en) 1974-06-05
FR2103639B1 (enExample) 1975-08-01
AU448887B2 (en) 1974-05-30
FR2103639A1 (enExample) 1972-04-14
AU3271371A (en) 1973-03-01

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